Guest guest Posted July 9, 2006 Report Share Posted July 9, 2006 Hi, I'm a newbie post, so I hope my post is in compliance with your guidelines. Thanks for your patience. I'm wondering if Creatine could be used to help anti-aging? Let's consider the mitochondria for a moment -- they are what creates ATP for your body in the first place. And we know that the very respiration process that they use to make the ATP can also fry the genes floating around in the mitochondria. This gradual self-damage to the mitochondria is considered to be a significant source of aging. The Reactive Oxidative Species (ROS) produced by the normal operation of your mitochondria gradually damage not only the mitochondria themselves, but as damage becomes sufficient, the ROS can even leak out into the rest of your cell and damage it too. But suppose you were to regularly take an external supplement of ATP, in the form of Creatine. Then your mitochondria might not have to work so hard to make it. This means less mitochondrial respiration, and thus likely less damage to mitochondrial genes over time. People are used to only thinking of taking Creatine for workouts, track meets, swim meets, sports games, dance class, etc, where sudden bursts of energy demand are required. But what if you were to just take small amounts of Creatine on a regular basis, independent of any workout considerations. Will it help you to make your mitochondria last longer? Wouldn't taking Creatine still be consistent with Calorie Restriction, since you're bypassing your whole metabolism to get your ATP directly from external intake? The whole point of Caloric Restriction is to deprive your metabolism of work, since that work causes wear and tear on your cells. We've all heard about the animal studies on CR and their superior life-extending results. What if the same tests were to be done under CR but also including the intake of Creatine as a supplement to the regular CR diet? I began thinking about this after my thoughts on Chondroitin/GAGs. After all, if you ingest pre-made complex/energetic molecules through your diet, rather than forcing your own metabolic processes to generate them, then you are creating less work for your metabolism. Less work for your metabolism means less production of ROS. And less production of ROS means less damage to your genome and cellular components. Comments, please? Quote Link to comment Share on other sites More sharing options...
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