Guest guest Posted May 11, 2006 Report Share Posted May 11, 2006 This kinda changes some of the thoughts of Vitamin E having no effect in this arguement. Al, is there any other corresponding word coming out about this that I haven't caught? I'll definately pass this on to the person in my life that is at risk. Regards, Don White Seguin, Tx > >Message 3 > From: " Al Young " acyoung@... > Date: Wed May 10, 2006 1:26pm(PDT) >Subject: High Omega-3 Polyunsaturated Fatty Acid Intake May Reduce Risk for A > > >I hope this makes it to the list, I've been having trouble lately getting my >posts to show up (on both crcommunity & ) > >Al > >May 1, 2006 - A diet high in omega-3 polyunsaturated fatty acids (PUFAs) and >vitamin E reduces the risk for amyotrophic lateral sclerosis (ALS), >according to the results of a case-control study reported in the April 28 >Online First issue of the Journal of Neurology, Neurosurgery, and >Psychiatry. > > *message truncated for space considerations* Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2006 Report Share Posted May 12, 2006 Can you tell me how CR and ALS have a connection please? I've kinda come in half way through, I think! PP-G Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2006 Report Share Posted May 12, 2006 Hi Don. I'm not particularly familiar with the subject, I posted this Medscape article in light of Roy Walford and the related suspicion that ALS and CR may have some connections. However, I'll keep you in mind regarding ALS articles that I may run across. Al > This kinda changes some of the thoughts of Vitamin E having no effect in > this > arguement. Al, is there any other corresponding word coming out about this > that I haven't caught? I'll definately pass this on to the person in my > life that > is at risk. > > Regards, > Don White > Seguin, Tx Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2006 Report Share Posted May 12, 2006 > Can you tell me how CR and ALS have a connection please? I've kinda come > in > half way through, I think! > PP-G Roy Walford (author of Beyond the 120 Year Diet, a book that most everyone in this group has read) died of ALS at age 79. So, there's the suspicion among some that CR may have figured into the etiology of his disease. In addition (I had forgotten about this), ALS is apparently disproportionately represented among endurance athletes - that are often also (like CRONistas) very lean. Al Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2006 Report Share Posted May 12, 2006 Al Young and everyone: ALS and CR have no connection. First of all, Roy is only one mouse. S econdly, please read the extensive file (Dr Walford's Posts) that we have which discusses Dr W's illness and how he may have contracted it. Implying that there is some sort of connection is bad science. Please post only, facts, studies etc and refrain from speculation. People that speculate are warned that they will put on a " moderate " status. If you got this idea elsewhere, then show us the " proof " . on 5/12/2006 12:49 PM, Al Young at acyoung@... wrote: > Can you tell me how CR and ALS have a connection please? I've kinda come > in > half way through, I think! > PP-G Roy Walford (author of Beyond the 120 Year Diet, a book that most everyone in this group has read) died of ALS at age 79. So, there's the suspicion among some that CR may have figured into the etiology of his disease. In addition (I had forgotten about this), ALS is apparently disproportionately represented among endurance athletes - that are often also (like CRONistas) very lean. Al Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2006 Report Share Posted May 12, 2006 Hi folks: If anyone can find any serious information about any recognized risk factors for ALS I would be interested to see it. I did a quick search and found that there was pretty well nothing that any serious observers could say was *confirmed* as a risk factor for ALS. But all kinds of things were suspected - NOT including slimness or CRON, incidentally. Athletic activity was mentioned in one source, but then was followed by the comment that a recent dutch study had found no connection at all between athletic activity and ALS. There were many unusual things about Dr. Walford, just one of which was CRON. He was very active athletically. He had a history of not reacting well to low oxygen environments - at altitude for example - and Biosphere 2 was just such a situation. There is also a connection between certain types of edible plants (notably including sweet potatoes of which huge quantities were eaten in Biosphere 2) and toxins (cyanide, specifically) related to 'neurologic disorders'. But as regards CRON and ALS, if we begin to see a few more CRONistas come down with ALS then certainly we should then pay close attention. Or if more Biospherians get it similarly we should sit up and take note. But one mouse, out of a few thousand, who had many other unusual characteristics, " does not a summer make " . IMO, something to keep in the back of one's mind in case future cases turn up. But other than that, meaningless until that happens, or some persuasive evidence emerges. Risk factor information .......... for example: " Risk Factors Risk factors include an inherited genetic defect, which accounts for 5–10% of cases of familial ALS (FALS) in the United States. FALS is linked to a genetic defect on chromosome 21. This gene codes for an enzyme called superoxide dismutase (SOD), an antioxidant that protects motor neurons from free radical damage (i.e., molecules introduced to the body, or produced by body processes that interact and cause cellular damage). More than 60 different mutations that cause SOD to lose its antioxidant properties have been found. However, only 40% of familial ALS cases are linked to SOD mutations, so there may be other unknown genetic defects involved. In the United States, 90–95% of ALS cases are sporadic. Sporadic ALS appears to be increasing worldwide. The causes are not clear, yet some evidence suggests that the immune system may be involved. Excessive levels of glutamate can overstimulate motor neurons and cause them to die. Glutamate is one of the most important neurotransmitters for healthy brain function. Neurotransmitters are chemicals that transmit signals from one nerve to another. In Guamanian ALS, a dietary neurotoxin is the risk factor. The suspected neurotoxin is an amino acid (BMAA) found in the seed of the cycad Cyas cirinalis, a tropical plant found in Guam, which was used to make flour and was a major dietary component during the 1950s and the early 1960s, when this type of ALS had an exceptionally high incidence. Causes The cause of ALS is not completely understood. Researchers and physicians suspect viruses, neurotoxins (especially in Guamanian ALS), heavy metals, DNA defects (especially in familial ALS), immune system abnormalities, and enzyme abnormalities. " Source: http://www.neurologychannel.com/als/ Rodney. > > > > > > Can you tell me how CR and ALS have a connection please? I've kinda come > > in > > half way through, I think! > > PP-G > > Roy Walford (author of Beyond the 120 Year Diet, a book that most everyone > in this group has read) died of ALS at age 79. So, there's the suspicion > among some that CR may have figured into the etiology of his disease. > > In addition (I had forgotten about this), ALS is apparently > disproportionately represented among endurance athletes - that are often > also (like CRONistas) very lean. > > Al > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2006 Report Share Posted May 13, 2006 Here's an interesting look at body mass and athletics in ALS http://tinyurl.com/r3egu http://www.cumc.columbia.edu/dept/sergievsky/cnd/pdfs/Premorbidweight.pdf Al Quote Link to comment Share on other sites More sharing options...
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