RE: Overeating increases BMR

January 31, 2006

I believe the changes in metabolic rate, either increased due to

overeating or decrease due to undereating are short term

adaptive/compensatory changes. Are there studies showing this is along

term change?

Also, the thermal effect of food, averaging about 10% for a mixed diet,

will change based on increases or decreases in calorie intake. so,

eating more or less would have an equivalent effect on TEF and hence

metabolic rate.

Jeff

January 31, 2006

I believe the changes in metabolic rate, either increased due to

overeating or decrease due to undereating are short term

adaptive/compensatory changes. Are there studies showing this is along

term change?

Also, the thermal effect of food, averaging about 10% for a mixed diet,

will change based on increases or decreases in calorie intake. so,

eating more or less would have an equivalent effect on TEF and hence

metabolic rate.

Jeff

January 31, 2006

Jeff,

I have looked more into the decrease in BMR associated with CR. The

changes seem to be permanent as long as the caloric level remains low.

Some CRONies, e.g., Liza May, who has been on CR for over 20 years

have substantially lower BMR than calculated with the Mifflin-St Jeor

equations.

I imagine that the opposite is also true. As long as you overeat,

your BMR will be higher.

The body adjusts BMR based on the availability of food. This fact

provides support for the concept of " set point " , but unfortunately not

enough to be able to quantify it. " Set point " would correspond to the

caloric intake where the BMR is neither increased nor decreased by a

corresponding deficit or surplus of food, i.e., Perfect Balance.

Tony

>

> I believe the changes in metabolic rate, either increased due to

> overeating or decrease due to undereating are short term

> adaptive/compensatory changes. Are there studies showing this is along

> term change?

>

> Also, the thermal effect of food, averaging about 10% for a mixed diet,

> will change based on increases or decreases in calorie intake. so,

> eating more or less would have an equivalent effect on TEF and hence

> metabolic rate.

>

> Jeff

>

January 31, 2006

Jeff,

I have looked more into the decrease in BMR associated with CR. The

changes seem to be permanent as long as the caloric level remains low.

Some CRONies, e.g., Liza May, who has been on CR for over 20 years

have substantially lower BMR than calculated with the Mifflin-St Jeor

equations.

I imagine that the opposite is also true. As long as you overeat,

your BMR will be higher.

The body adjusts BMR based on the availability of food. This fact

provides support for the concept of " set point " , but unfortunately not

enough to be able to quantify it. " Set point " would correspond to the

caloric intake where the BMR is neither increased nor decreased by a

corresponding deficit or surplus of food, i.e., Perfect Balance.

Tony

>

> I believe the changes in metabolic rate, either increased due to

> overeating or decrease due to undereating are short term

> adaptive/compensatory changes. Are there studies showing this is along

> term change?

>

> Also, the thermal effect of food, averaging about 10% for a mixed diet,

> will change based on increases or decreases in calorie intake. so,

> eating more or less would have an equivalent effect on TEF and hence

> metabolic rate.

>

> Jeff

>

January 31, 2006

Hi folks:

It looks like it is permanent. Energy expenditure in rhesus monkeys

on CR for eleven years:

" Energy expenditure of rhesus monkeys subjected to 11 years of

dietary restriction.

Blanc S, Schoeller D, Kemnitz J, Weindruch R, Colman R, Newton W,

Wink K, Baum S, Ramsey J.

Department of Nutritional Sciences, University of Wisconsin-Madison,

Madison, Wisconsin 53706-1571, USA.

Dietary restriction (DR) is currently the only paradigm that has

consistently extended maximal life span and reduced the onset of age-

related chronic diseases in all of the nonprimate species tested.

Although it is controversial, some investigators have suggested that

the underlying mechanisms may be mediated by adaptations in energy

expenditure. We evaluated the extent to which DR alters energy

metabolism in a unique cohort of rhesus monkeys submitted to DR for

11 yr. Total energy expenditure (doubly labeled water), resting

energy expenditure (REE; indirect calorimetry), and nonbasal energy

expenditure (calculated by difference) were measured in DR (n = 12)

and control (n = 11) animals. Body composition was determined by dual

energy x-ray absorptiometry. Both fat mass and fat-free mass were

lower in the restricted animals (56 and 12%, respectively). DR

induced a 17% lower total energy expenditure that was attributable to

a 20% decrease in REE without changes in the nonbasal energy

expenditure. Adjusted for fat-free mass, REE was 13% lower with DR (-

250 kJ/d). Taken together with a reanalysis of previous DR

experiments published in humans, rodents, and monkeys, these results

suggest that DR may lower REE independent of the DR-induced changes

in body composition. Whether this reduction in REE contributes to the

life-extending properties of DR warrants further analysis, but it

suggests that the long-standing debate regarding DR effects on

metabolic rates may derive from the lack of consensus on how to

adjust for body size and composition. "

PMID: 12519821

Rodney.

>

> Jeff,

>

> I have looked more into the decrease in BMR associated with CR. The

> changes seem to be permanent as long as the caloric level remains

low.

> Some CRONies, e.g., Liza May, who has been on CR for over 20 years

> have substantially lower BMR than calculated with the Mifflin-St

Jeor

> equations.

>

> I imagine that the opposite is also true. As long as you overeat,

> your BMR will be higher.

>

> The body adjusts BMR based on the availability of food. This fact

> provides support for the concept of " set point " , but unfortunately

not

> enough to be able to quantify it. " Set point " would correspond to

the

> caloric intake where the BMR is neither increased nor decreased by a

> corresponding deficit or surplus of food, i.e., Perfect Balance.

>

> Tony

>

> --- In , " Jeff Novick " <jnovick@p...>

wrote:

> >

> > I believe the changes in metabolic rate, either increased due to

> > overeating or decrease due to undereating are short term

> > adaptive/compensatory changes. Are there studies showing this

is along

> > term change?

> >

> > Also, the thermal effect of food, averaging about 10% for a mixed

diet,

> > will change based on increases or decreases in calorie intake.

so,

> > eating more or less would have an equivalent effect on TEF and

hence

> > metabolic rate.

> >

> > Jeff

> >

>

January 31, 2006