Dietary Fat and Breast Cancer

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Dietary fat and breast cancer in Saudi Arabia: a case-control study.

Alothaimeen A, Ezzat A, Mohamed G, Muammar T, Al-Madouj A.

Department of Biostatistics, Epidemiology and Scientific Computing,

Nutrition Research, Riyadh, Saudi Arabia.

A case-control study investigated the association between dietary fat

and breast cancer in Saudi Arabian women attending a specialist

hospital in Riyadh. Women with breast carcinoma (n= 499) newly

diagnosed between 1996-2002, and control women (n = 498) randomly

selected from patients' attendants and relatives, completed a food

frequency questionnaire. Serum levels of triglycerides and total

cholesterol were measured. A significant positive association was

found between risk of breast cancer and intake of fats, protein and

calories. Adjusted odds ratios for the highest quartile of intake

versus the lowest were 2.43 for saturated fat, 2.25 for animal

protein, 2.12 for polyunsaturated fat, 1.88 for cholesterol and 2.69

for total energy from dietary intake. For serum triglycerides the

adjusted odds ratio was 2.16 for the highest quartile.

PMID: 1633577