Re: Zinc and prostate cancer

[Guest guest]

Well, Radio, I've done much the same for the same reasons in the last 6 months.

I did a comprehensive review of a new vitamin which megadosed the B's and I came to the conclusion I needed to quit the MV's.

I now just take a 1/2 sp of cod liver oil for DHA/EPA.

My BP is lower with no weight loss. I do eat things like carrots (raw), tomatoes (raw), walnuts (raw), papaya (fresh), orange (fresh), prune juice (canned), broccoli, romaine, etc, for nutrients.

And I've been looking for a supplement that would provide just the selenium - some eat brazil nuts.

I also use ginger, fresh ginger, a slice in my tea or coffee. It effects my digestion and gut.

There is on thing, magnesium, which is hard to get in foods, so I take a Mg oxide tablet containing 125% RDA.

And no Vitamin D supplements. That means I dropped milk, in favor of plain low fat yogurt, buttermilk. I get plenty of sun.

One thing I've taken for a long time is l-carnitine. Seems to help with fat metabolism and transport.

FWIW, I've a lot of "Foods rich in zinc include chicken, eggs, cheese, oysters, beef, and peanuts. "

And I never had PCa yet (ha, ha, ha). I've also lived mostly in the south U.S. and never Georgia.

Another point is I have very little morning soreness now without the NSAID, and the funny thing is I can only relate that to the -MV or the -milk.

Regards.

[ ] Zinc and prostate cancer

Here is a well written and balanced article on the effects of zinc on reducing the risk of prostate cancer.http://health.msn.com/healthnews/ArticlePage.aspx?cp-documentid=100127820The article quotes a number of studies that suggest that modest levels of zinc supplementation has no effect either way. However, large zinc supplementation may actually promote prostate growth.Over the years, I have been reducing my intake of dietary supplements.Beta-carotene supplements were the first to go in the early 1990's.And then iron soon thereafter.This caused me to stop taking general supplements, since all general supplements contain beta-carotene and iron.Recently, I stopped taking folate acid which I have been taking since 1999 to reduce homoceistiene levels. Studies, well-documented in this support group, show that folate supplementation has no benefit in reducing heart disease. Instead, I am making sure that I receive sufficient folate acid from dietary sources instead of through supplementation sources.Now, I am dropping zinc from my supplementation use as a result of this article.I am now left with selenium (for cancer in general and prostate health in specific), ginger tablets (for inflammation), baker's yeast (for the 10 essential amino acids after weight training, as well as chromium), and vitamin D (about 1000 IU's per day).I am now taking all the essential minerals and vitamins etc. from dietary sources instead of from supplementation.Furthermore, I am picking foods where the essential minerals etc. are naturally occuring, and not added through supplementation.

[Guest guest]

Well, Radio, I've done much the same for the same reasons in the last 6 months.

I did a comprehensive review of a new vitamin which megadosed the B's and I came to the conclusion I needed to quit the MV's.

I now just take a 1/2 sp of cod liver oil for DHA/EPA.

My BP is lower with no weight loss. I do eat things like carrots (raw), tomatoes (raw), walnuts (raw), papaya (fresh), orange (fresh), prune juice (canned), broccoli, romaine, etc, for nutrients.

And I've been looking for a supplement that would provide just the selenium - some eat brazil nuts.

I also use ginger, fresh ginger, a slice in my tea or coffee. It effects my digestion and gut.

There is on thing, magnesium, which is hard to get in foods, so I take a Mg oxide tablet containing 125% RDA.

And no Vitamin D supplements. That means I dropped milk, in favor of plain low fat yogurt, buttermilk. I get plenty of sun.

One thing I've taken for a long time is l-carnitine. Seems to help with fat metabolism and transport.

FWIW, I've a lot of "Foods rich in zinc include chicken, eggs, cheese, oysters, beef, and peanuts. "

And I never had PCa yet (ha, ha, ha). I've also lived mostly in the south U.S. and never Georgia.

Another point is I have very little morning soreness now without the NSAID, and the funny thing is I can only relate that to the -MV or the -milk.

Regards.

[ ] Zinc and prostate cancer

Here is a well written and balanced article on the effects of zinc on reducing the risk of prostate cancer.http://health.msn.com/healthnews/ArticlePage.aspx?cp-documentid=100127820The article quotes a number of studies that suggest that modest levels of zinc supplementation has no effect either way. However, large zinc supplementation may actually promote prostate growth.Over the years, I have been reducing my intake of dietary supplements.Beta-carotene supplements were the first to go in the early 1990's.And then iron soon thereafter.This caused me to stop taking general supplements, since all general supplements contain beta-carotene and iron.Recently, I stopped taking folate acid which I have been taking since 1999 to reduce homoceistiene levels. Studies, well-documented in this support group, show that folate supplementation has no benefit in reducing heart disease. Instead, I am making sure that I receive sufficient folate acid from dietary sources instead of through supplementation sources.Now, I am dropping zinc from my supplementation use as a result of this article.I am now left with selenium (for cancer in general and prostate health in specific), ginger tablets (for inflammation), baker's yeast (for the 10 essential amino acids after weight training, as well as chromium), and vitamin D (about 1000 IU's per day).I am now taking all the essential minerals and vitamins etc. from dietary sources instead of from supplementation.Furthermore, I am picking foods where the essential minerals etc. are naturally occuring, and not added through supplementation.

[Guest guest]

Hi Rad:

Jftr .......... that article says that people in north America get

enough zinc from their diet.

BUT **WE** ARE NOT ON THE SAD DIET!!!! For a start, we are eating

much less in total. And also very much less of certain things that

the SADDISTAS eat lots of (which for all I know may contain lots of

zinc).

When I logged everything I ate for a month into Fitday (at a time I

was consuming an average of 1500 calories daily) it told me my zinc

intake was 50% below the RDA. Not only did Fitday say that, but in

addition a nutritionist at a drug store (only the second intelligent

nutritionist I have ever encountered, the other one posts here!)

PREDICTED what my deficiencies would be after I told her the kind of

diet I was eating - one of which she predicted would be zinc.

SO ......... my suggestion is to not take this article's word for

it that you are getting plenty of zinc. Check for yourself to make

sure. And you do not want too much, either. I have brought my

intake up to the RDA by taking one zinc tablet a week.

Looking at the list of problems a zinc deficiency is supposed to

cause, one sure would to fix a deficiency if one had one.

Rodney.

>

> Here is a well written and balanced article on the effects of zinc

on

> reducing the risk of prostate cancer.

>

> http://health.msn.com/healthnews/ArticlePage.aspx?cp-

> documentid=100127820

>

> The article quotes a number of studies that suggest that modest

> levels of zinc supplementation has no effect either way. However,

> large zinc supplementation may actually promote prostate growth.

>

> Over the years, I have been reducing my intake of dietary

supplements.

>

> Beta-carotene supplements were the first to go in the early 1990's.

>

> And then iron soon thereafter.

>

> This caused me to stop taking general supplements, since all

general

> supplements contain beta-carotene and iron.

>

> Recently, I stopped taking folate acid which I have been taking

since

> 1999 to reduce homoceistiene levels. Studies, well-documented in

> this support group, show that folate supplementation has no benefit

> in reducing heart disease. Instead, I am making sure that I

receive

> sufficient folate acid from dietary sources instead of through

> supplementation sources.

>

> Now, I am dropping zinc from my supplementation use as a result of

> this article.

>

> I am now left with selenium (for cancer in general and prostate

> health in specific), ginger tablets (for inflammation), baker's

yeast

> (for the 10 essential amino acids after weight training, as well as

> chromium), and vitamin D (about 1000 IU's per day).

>

> I am now taking all the essential minerals and vitamins etc. from

> dietary sources instead of from supplementation.

>

> Furthermore, I am picking foods where the essential minerals etc.

are

> naturally occuring, and not added through supplementation.

>

[Guest guest]

Hi Rad:

Jftr .......... that article says that people in north America get

enough zinc from their diet.

BUT **WE** ARE NOT ON THE SAD DIET!!!! For a start, we are eating

much less in total. And also very much less of certain things that

the SADDISTAS eat lots of (which for all I know may contain lots of

zinc).

When I logged everything I ate for a month into Fitday (at a time I

was consuming an average of 1500 calories daily) it told me my zinc

intake was 50% below the RDA. Not only did Fitday say that, but in

addition a nutritionist at a drug store (only the second intelligent

nutritionist I have ever encountered, the other one posts here!)

PREDICTED what my deficiencies would be after I told her the kind of

diet I was eating - one of which she predicted would be zinc.

SO ......... my suggestion is to not take this article's word for

it that you are getting plenty of zinc. Check for yourself to make

sure. And you do not want too much, either. I have brought my

intake up to the RDA by taking one zinc tablet a week.

Looking at the list of problems a zinc deficiency is supposed to

cause, one sure would to fix a deficiency if one had one.

Rodney.

>

> Here is a well written and balanced article on the effects of zinc

on

> reducing the risk of prostate cancer.

>

> http://health.msn.com/healthnews/ArticlePage.aspx?cp-

> documentid=100127820

>

> The article quotes a number of studies that suggest that modest

> levels of zinc supplementation has no effect either way. However,

> large zinc supplementation may actually promote prostate growth.

>

> Over the years, I have been reducing my intake of dietary

supplements.

>

> Beta-carotene supplements were the first to go in the early 1990's.

>

> And then iron soon thereafter.

>

> This caused me to stop taking general supplements, since all

general

> supplements contain beta-carotene and iron.

>

> Recently, I stopped taking folate acid which I have been taking

since

> 1999 to reduce homoceistiene levels. Studies, well-documented in

> this support group, show that folate supplementation has no benefit

> in reducing heart disease. Instead, I am making sure that I

receive

> sufficient folate acid from dietary sources instead of through

> supplementation sources.

>

> Now, I am dropping zinc from my supplementation use as a result of

> this article.

>

> I am now left with selenium (for cancer in general and prostate

> health in specific), ginger tablets (for inflammation), baker's

yeast

> (for the 10 essential amino acids after weight training, as well as

> chromium), and vitamin D (about 1000 IU's per day).

>

> I am now taking all the essential minerals and vitamins etc. from

> dietary sources instead of from supplementation.

>

> Furthermore, I am picking foods where the essential minerals etc.

are

> naturally occuring, and not added through supplementation.

>

[Guest guest]

Rodney,

You say: " at a time I was consuming an average of 1500 calories

daily " . Are you still on this regimen? That is approximately 25%-30%

CR for you.

I ask because I consider you to be my age-matched control. From your

BMI in the database (22.2) you weigh about 4 pounds less than I do,

yet I eat about 2000 calories per day.

I am wondering if you are losing weight or not. If I don't eat my

2000 calories, my weight starts to drop fairly fast with my level of

activity.

Tony

>

> Hi Rad:

>

> Jftr .......... that article says that people in north America get

> enough zinc from their diet.

>

> BUT **WE** ARE NOT ON THE SAD DIET!!!! For a start, we are eating

> much less in total. And also very much less of certain things that

> the SADDISTAS eat lots of (which for all I know may contain lots of

> zinc).

>

> When I logged everything I ate for a month into Fitday (at a time I

> was consuming an average of 1500 calories daily) it told me my zinc

> intake was 50% below the RDA. Not only did Fitday say that, but in

> addition a nutritionist at a drug store (only the second intelligent

> nutritionist I have ever encountered, the other one posts here!)

> PREDICTED what my deficiencies would be after I told her the kind of

> diet I was eating - one of which she predicted would be zinc.

>

> SO ......... my suggestion is to not take this article's word for

> it that you are getting plenty of zinc. Check for yourself to make

> sure. And you do not want too much, either. I have brought my

> intake up to the RDA by taking one zinc tablet a week.

>

> Looking at the list of problems a zinc deficiency is supposed to

> cause, one sure would to fix a deficiency if one had one.

>

> Rodney.

>

[Guest guest]

Rodney,

You say: " at a time I was consuming an average of 1500 calories

daily " . Are you still on this regimen? That is approximately 25%-30%

CR for you.

I ask because I consider you to be my age-matched control. From your

BMI in the database (22.2) you weigh about 4 pounds less than I do,

yet I eat about 2000 calories per day.

I am wondering if you are losing weight or not. If I don't eat my

2000 calories, my weight starts to drop fairly fast with my level of

activity.

Tony

>

> Hi Rad:

>

> Jftr .......... that article says that people in north America get

> enough zinc from their diet.

>

> BUT **WE** ARE NOT ON THE SAD DIET!!!! For a start, we are eating

> much less in total. And also very much less of certain things that

> the SADDISTAS eat lots of (which for all I know may contain lots of

> zinc).

>

> When I logged everything I ate for a month into Fitday (at a time I

> was consuming an average of 1500 calories daily) it told me my zinc

> intake was 50% below the RDA. Not only did Fitday say that, but in

> addition a nutritionist at a drug store (only the second intelligent

> nutritionist I have ever encountered, the other one posts here!)

> PREDICTED what my deficiencies would be after I told her the kind of

> diet I was eating - one of which she predicted would be zinc.

>

> SO ......... my suggestion is to not take this article's word for

> it that you are getting plenty of zinc. Check for yourself to make

> sure. And you do not want too much, either. I have brought my

> intake up to the RDA by taking one zinc tablet a week.

>

> Looking at the list of problems a zinc deficiency is supposed to

> cause, one sure would to fix a deficiency if one had one.

>

> Rodney.

>

[Guest guest]

Hi Tony:

No. I am eating more now than I was then. I mentioned that amount

to make the point that at that time my pretty low caloric intake

would in part account for nutrient deficiencies.

Over the past six months I have been losing weight VERY slowly (the

trend is only just discernible (!) in the chart with all the

gyrations from week to week). In the six months prior to that I had

been gaining at an equally slow pace. So there has been no material

net change the past twelve months. And I have not measured my

caloric intake accurately for quite some time. If I had to guess I

would say my current intake is definitely above 1500 and definitely

below 2000. Perhaps 1800. But that is approximate.

I am planning (plans can go awry!) to lower my BMI to 21 over the

coming six to eighteen months. Then stabilize there and think very

carefully before making any further changes. Part of the long think

will be to have a whole lot of tests done again when I get there,

compare my key biomarkers with those of others here who I regard as

being " as close to established CRON status as matters " , and then

perhaps decide, largely on the basis of those comparisons, what if

anything I should do next. Doing another full month assessment of my

nutrient intake will also be part of this process.

This is one reason I suggested a couple of weeks ago we might put

together an analysis of people's biomarkers, to calculate a 'percent

degreee of CRON'. We could then each compare our own data with the

range among the rest of us and come to some conclusion about whether

we need to raise our caloric intake say fifty calories, or nudge it

down another fifty calories.

For example, if I found my biomarkers, on average, as measured

by 'percentage degree of CRON' were considerably less good than those

of the group I would regard as fully CRONized, then it would suggest

I need to do more - cut intake a little more. But if I were to find

my biomarkers showed me to be at 110% of full CRON status even when

consuming 2000 calories, say, then I might consider instead that I

was overdoing it and should ease up by eating a little more and

bringing my number down from 110% of CRON to 100%, or 95% or whatever.

But not many people have so far asked me to do their assessment.

***So, guys and gals, feel free to send me your current biomarkers

data if you want a 'percentage degree of CRON' assessment done. I

will never release any of your data without specific written (email)

approval from you. There is the potential for us all to learn a lot

from this if we have a large enough sample to draw conclusions from.

Thirty people would be enough I think.***

[since, Tony, you did ask ; ^ )))]

Rodney.

>

> Rodney,

>

> You say: " at a time I was consuming an average of 1500 calories

> daily " . Are you still on this regimen? That is approximately 25%-

30%

> CR for you.

>

> I ask because I consider you to be my age-matched control. From

your

> BMI in the database (22.2) you weigh about 4 pounds less than I do,

> yet I eat about 2000 calories per day.

>

> I am wondering if you are losing weight or not. If I don't eat my

> 2000 calories, my weight starts to drop fairly fast with my level of

> activity.

>

> Tony

>

>

> --- In , " Rodney " <perspect1111@>

wrote:

> >

> > Hi Rad:

> >

> > Jftr .......... that article says that people in north America

get

> > enough zinc from their diet.

> >

> > BUT **WE** ARE NOT ON THE SAD DIET!!!! For a start, we are

eating

> > much less in total. And also very much less of certain things

that

> > the SADDISTAS eat lots of (which for all I know may contain lots

of

> > zinc).

> >

> > When I logged everything I ate for a month into Fitday (at a time

I

> > was consuming an average of 1500 calories daily) it told me my

zinc

> > intake was 50% below the RDA. Not only did Fitday say that, but

in

> > addition a nutritionist at a drug store (only the second

intelligent

> > nutritionist I have ever encountered, the other one posts here!)

> > PREDICTED what my deficiencies would be after I told her the kind

of

> > diet I was eating - one of which she predicted would be zinc.

> >

> > SO ......... my suggestion is to not take this article's word

for

> > it that you are getting plenty of zinc. Check for yourself to

make

> > sure. And you do not want too much, either. I have brought my

> > intake up to the RDA by taking one zinc tablet a week.

> >

> > Looking at the list of problems a zinc deficiency is supposed to

> > cause, one sure would to fix a deficiency if one had one.

> >

> > Rodney.

> >

>

[Guest guest]

Hi Tony:

No. I am eating more now than I was then. I mentioned that amount

to make the point that at that time my pretty low caloric intake

would in part account for nutrient deficiencies.

Over the past six months I have been losing weight VERY slowly (the

trend is only just discernible (!) in the chart with all the

gyrations from week to week). In the six months prior to that I had

been gaining at an equally slow pace. So there has been no material

net change the past twelve months. And I have not measured my

caloric intake accurately for quite some time. If I had to guess I

would say my current intake is definitely above 1500 and definitely

below 2000. Perhaps 1800. But that is approximate.

I am planning (plans can go awry!) to lower my BMI to 21 over the

coming six to eighteen months. Then stabilize there and think very

carefully before making any further changes. Part of the long think

will be to have a whole lot of tests done again when I get there,

compare my key biomarkers with those of others here who I regard as

being " as close to established CRON status as matters " , and then

perhaps decide, largely on the basis of those comparisons, what if

anything I should do next. Doing another full month assessment of my

nutrient intake will also be part of this process.

This is one reason I suggested a couple of weeks ago we might put

together an analysis of people's biomarkers, to calculate a 'percent

degreee of CRON'. We could then each compare our own data with the

range among the rest of us and come to some conclusion about whether

we need to raise our caloric intake say fifty calories, or nudge it

down another fifty calories.

For example, if I found my biomarkers, on average, as measured

by 'percentage degree of CRON' were considerably less good than those

of the group I would regard as fully CRONized, then it would suggest

I need to do more - cut intake a little more. But if I were to find

my biomarkers showed me to be at 110% of full CRON status even when

consuming 2000 calories, say, then I might consider instead that I

was overdoing it and should ease up by eating a little more and

bringing my number down from 110% of CRON to 100%, or 95% or whatever.

But not many people have so far asked me to do their assessment.

***So, guys and gals, feel free to send me your current biomarkers

data if you want a 'percentage degree of CRON' assessment done. I

will never release any of your data without specific written (email)

approval from you. There is the potential for us all to learn a lot

from this if we have a large enough sample to draw conclusions from.

Thirty people would be enough I think.***

[since, Tony, you did ask ; ^ )))]

Rodney.

>

> Rodney,

>

> You say: " at a time I was consuming an average of 1500 calories

> daily " . Are you still on this regimen? That is approximately 25%-

30%

> CR for you.

>

> I ask because I consider you to be my age-matched control. From

your

> BMI in the database (22.2) you weigh about 4 pounds less than I do,

> yet I eat about 2000 calories per day.

>

> I am wondering if you are losing weight or not. If I don't eat my

> 2000 calories, my weight starts to drop fairly fast with my level of

> activity.

>

> Tony

>

>

> --- In , " Rodney " <perspect1111@>

wrote:

> >

> > Hi Rad:

> >

> > Jftr .......... that article says that people in north America

get

> > enough zinc from their diet.

> >

> > BUT **WE** ARE NOT ON THE SAD DIET!!!! For a start, we are

eating

> > much less in total. And also very much less of certain things

that

> > the SADDISTAS eat lots of (which for all I know may contain lots

of

> > zinc).

> >

> > When I logged everything I ate for a month into Fitday (at a time

I

> > was consuming an average of 1500 calories daily) it told me my

zinc

> > intake was 50% below the RDA. Not only did Fitday say that, but

in

> > addition a nutritionist at a drug store (only the second

intelligent

> > nutritionist I have ever encountered, the other one posts here!)

> > PREDICTED what my deficiencies would be after I told her the kind

of

> > diet I was eating - one of which she predicted would be zinc.

> >

> > SO ......... my suggestion is to not take this article's word

for

> > it that you are getting plenty of zinc. Check for yourself to

make

> > sure. And you do not want too much, either. I have brought my

> > intake up to the RDA by taking one zinc tablet a week.

> >

> > Looking at the list of problems a zinc deficiency is supposed to

> > cause, one sure would to fix a deficiency if one had one.

> >

> > Rodney.

> >

>

[Guest guest]

What textbooks do the nutritionists trained in CR use?

Is fitday a CR product?

Regards.

[ ] Re: Zinc and prostate cancer

Hi Rad:Jftr .......... that article says that people in north America get enough zinc from their diet.BUT **WE** ARE NOT ON THE SAD DIET!!!! For a start, we are eating much less in total. And also very much less of certain things that the SADDISTAS eat lots of (which for all I know may contain lots of zinc).When I logged everything I ate for a month into Fitday (at a time I was consuming an average of 1500 calories daily) it told me my zinc intake was 50% below the RDA. Not only did Fitday say that, but in addition a nutritionist at a drug store (only the second intelligent nutritionist I have ever encountered, the other one posts here!) PREDICTED what my deficiencies would be after I told her the kind of diet I was eating - one of which she predicted would be zinc. SO ......... my suggestion is to not take this article's word for it that you are getting plenty of zinc. Check for yourself to make sure. And you do not want too much, either. I have brought my intake up to the RDA by taking one zinc tablet a week. Looking at the list of problems a zinc deficiency is supposed to cause, one sure would to fix a deficiency if one had one. Rodney. >> Here is a well written and balanced article on the effects of zinc on > reducing the risk of prostate cancer.> > http://health.msn.com/healthnews/ArticlePage.aspx?cp-> documentid=100127820> > The article quotes a number of studies that suggest that modest > levels of zinc supplementation has no effect either way. However, > large zinc supplementation may actually promote prostate growth.> > Over the years, I have been reducing my intake of dietary supplements.> > Beta-carotene supplements were the first to go in the early 1990's.> > And then iron soon thereafter.> > This caused me to stop taking general supplements, since all general > supplements contain beta-carotene and iron.> > Recently, I stopped taking folate acid which I have been taking since > 1999 to reduce homoceistiene levels. Studies, well-documented in > this support group, show that folate supplementation has no benefit > in reducing heart disease. Instead, I am making sure that I receive > sufficient folate acid from dietary sources instead of through > supplementation sources.> > Now, I am dropping zinc from my supplementation use as a result of > this article.> > I am now left with selenium (for cancer in general and prostate > health in specific), ginger tablets (for inflammation), baker's yeast > (for the 10 essential amino acids after weight training, as well as > chromium), and vitamin D (about 1000 IU's per day).> > I am now taking all the essential minerals and vitamins etc. from > dietary sources instead of from supplementation.> > Furthermore, I am picking foods where the essential minerals etc. are > naturally occuring, and not added through supplementation.>

[Guest guest]

What textbooks do the nutritionists trained in CR use?

Is fitday a CR product?

Regards.

[ ] Re: Zinc and prostate cancer

Hi Rad:Jftr .......... that article says that people in north America get enough zinc from their diet.BUT **WE** ARE NOT ON THE SAD DIET!!!! For a start, we are eating much less in total. And also very much less of certain things that the SADDISTAS eat lots of (which for all I know may contain lots of zinc).When I logged everything I ate for a month into Fitday (at a time I was consuming an average of 1500 calories daily) it told me my zinc intake was 50% below the RDA. Not only did Fitday say that, but in addition a nutritionist at a drug store (only the second intelligent nutritionist I have ever encountered, the other one posts here!) PREDICTED what my deficiencies would be after I told her the kind of diet I was eating - one of which she predicted would be zinc. SO ......... my suggestion is to not take this article's word for it that you are getting plenty of zinc. Check for yourself to make sure. And you do not want too much, either. I have brought my intake up to the RDA by taking one zinc tablet a week. Looking at the list of problems a zinc deficiency is supposed to cause, one sure would to fix a deficiency if one had one. Rodney. >> Here is a well written and balanced article on the effects of zinc on > reducing the risk of prostate cancer.> > http://health.msn.com/healthnews/ArticlePage.aspx?cp-> documentid=100127820> > The article quotes a number of studies that suggest that modest > levels of zinc supplementation has no effect either way. However, > large zinc supplementation may actually promote prostate growth.> > Over the years, I have been reducing my intake of dietary supplements.> > Beta-carotene supplements were the first to go in the early 1990's.> > And then iron soon thereafter.> > This caused me to stop taking general supplements, since all general > supplements contain beta-carotene and iron.> > Recently, I stopped taking folate acid which I have been taking since > 1999 to reduce homoceistiene levels. Studies, well-documented in > this support group, show that folate supplementation has no benefit > in reducing heart disease. Instead, I am making sure that I receive > sufficient folate acid from dietary sources instead of through > supplementation sources.> > Now, I am dropping zinc from my supplementation use as a result of > this article.> > I am now left with selenium (for cancer in general and prostate > health in specific), ginger tablets (for inflammation), baker's yeast > (for the 10 essential amino acids after weight training, as well as > chromium), and vitamin D (about 1000 IU's per day).> > I am now taking all the essential minerals and vitamins etc. from > dietary sources instead of from supplementation.> > Furthermore, I am picking foods where the essential minerals etc. are > naturally occuring, and not added through supplementation.>

[Guest guest]

> " Acute toxicity

>

> " Isolated outbreaks of acute zinc toxicity have occurred as a result of

> the consumption of food or beverages contaminated with zinc released

> from galvanized containers. Signs of acute zinc toxicity are abdominal

> pain, diarrhea, nausea, and vomiting. Single doses of 225 to 450 mg of

> zinc usually induce vomiting. Milder gastrointestinal distress has been

> reported at doses of 50 to 150 mg/day of supplemental zinc. Metal fume

> fever has been reported after the inhalation of zinc oxide fumes.

> Specifically, profuse sweating, weakness, and rapid breathing may

> develop within eight hours of zinc oxide inhalation and persist 12-24

> hours after exposure is terminated.

>

> " Adverse effects

>

> " The major consequence of long-term consumption of excessive zinc is

> copper deficiency. Total zinc intakes of 60 mg/day (50 mg supplemental

> and 10 mg dietary zinc) have been found to result in signs of copper

> deficiency. In order to prevent copper deficiency, the U.S. Food and

> Nutrition Board set the tolerable upper level of intake (UL) for adults

> at 40 mg/day, including dietary and supplemental zinc " .

>

> The current RDA for zinc is 11mg/day. The upper safe limit 40mg daily.

> One 50mg zinc pill a week brings me up to the RDA. Alternatively, napa

> cabbage is an excellent source of zinc. Just ~35 calories of it daily

> (or 245 calories once a week) would provide the entire requirement.

>

> On the other side of the argument, 120 calories of napa every day and

> you would be in danger of overdosing zinc. For that matter just one

> 50mg zinc tablet daily would put me well over the upper safe limit when

> zinc from food is included.

>

> I give this simply as an example. These kinds of numbers suggest to me

> that everyone should track their usual daily food intake for a full week

> occasionally to determine if they may be going wrong somewhere

> ......... on the upside or the downside. When I do this I have

> consistently found I am deficient four micronutrients. But with rather

> minor adjustments to what I habitually eat I could easily be overdosing

> nutrients like selenium or zinc, and no doubt others.

>

> So the widespread belief about maximization of nutrients in the CRON

> community needs to be approached cautiously. Especially when we see

> evidence suggesting that in the case of some essential nutrients

> (methionine, for example, and how do we know there aren't others?) the

> smallest amount we can get away with may, possibly, turn out to be the

> best for longevity.

Then there's the PMID: 17292532

Eur Urol. 2007 Oct;52(4):1052-6. Epub 2007 Feb 5.

Dietary zinc and prostate cancer risk: a case-control study from Italy.

Gallus S, Foschi R, Negri E, Talamini R, Franceschi S, Montella M, Ramazzotti V,

Tavani A, Dal Maso L, La Vecchia C.

" CONCLUSIONS: In this large study we found a direct association between high

zinc intake

and prostate cancer risk, particularly for advanced cancers. Our findings allow

one to

exclude a favourable effect of zinc on prostate carcinogenesis. "

Thanks,

Todd

[Guest guest]

Hi Todd:

Thank you. And this one also:

Zinc supplement use and risk of prostate cancer.

Leitzmann MF, Stampfer MJ, Wu K, Colditz GA, Willett WC, Giovannucci EL.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA. leitzmann@...

The high concentration of zinc in the prostate suggests that zinc may play a role in prostate health. We examined the association between supplemental zinc intake and prostate cancer risk among 46 974 U.S. men participating in the Health Professionals Follow-Up Study. During 14 years of follow-up from 1986 through 2000, 2901 new cases of prostate cancer were ascertained, of which 434 cases were diagnosed as advanced cancer. Supplemental zinc intake at doses of up to 100 mg/day was not associated with prostate cancer risk. However, compared with nonusers, men who consumed more than 100 mg/day of supplemental zinc had a relative risk of advanced prostate cancer of 2.29 (95% confidence interval = 1.06 to 4.95; P(trend) =.003), and men who took supplemental zinc for 10 or more years had a relative risk of 2.37 (95% confidence interval = 1.42 to 3.95; P(trend)<.001). Although we cannot rule out residual confounding by supplemental calcium intake or some unmeasured correlate of zinc supplement use, our findings, that chronic zinc oversupply may play a role in prostate carcinogenesis, warrant further investigation.

PMID: 12837837

Rodney.

> > > "Acute toxicity> > > > "Isolated outbreaks of acute zinc toxicity have occurred as a result of> > the consumption of food or beverages contaminated with zinc released> > from galvanized containers. Signs of acute zinc toxicity are abdominal> > pain, diarrhea, nausea, and vomiting. Single doses of 225 to 450 mg of> > zinc usually induce vomiting. Milder gastrointestinal distress has been> > reported at doses of 50 to 150 mg/day of supplemental zinc. Metal fume> > fever has been reported after the inhalation of zinc oxide fumes.> > Specifically, profuse sweating, weakness, and rapid breathing may> > develop within eight hours of zinc oxide inhalation and persist 12-24> > hours after exposure is terminated.> > > > "Adverse effects> > > > "The major consequence of long-term consumption of excessive zinc is> > copper deficiency. Total zinc intakes of 60 mg/day (50 mg supplemental> > and 10 mg dietary zinc) have been found to result in signs of copper> > deficiency. In order to prevent copper deficiency, the U.S. Food and> > Nutrition Board set the tolerable upper level of intake (UL) for adults> > at 40 mg/day, including dietary and supplemental zinc".> > > > The current RDA for zinc is 11mg/day. The upper safe limit 40mg daily. > > One 50mg zinc pill a week brings me up to the RDA. Alternatively, napa> > cabbage is an excellent source of zinc. Just ~35 calories of it daily> > (or 245 calories once a week) would provide the entire requirement.> > > > On the other side of the argument, 120 calories of napa every day and> > you would be in danger of overdosing zinc. For that matter just one> > 50mg zinc tablet daily would put me well over the upper safe limit when> > zinc from food is included.> > > > I give this simply as an example. These kinds of numbers suggest to me> > that everyone should track their usual daily food intake for a full week> > occasionally to determine if they may be going wrong somewhere > > ......... on the upside or the downside. When I do this I have> > consistently found I am deficient four micronutrients. But with rather> > minor adjustments to what I habitually eat I could easily be overdosing> > nutrients like selenium or zinc, and no doubt others.> > > > So the widespread belief about maximization of nutrients in the CRON> > community needs to be approached cautiously. Especially when we see> > evidence suggesting that in the case of some essential nutrients> > (methionine, for example, and how do we know there aren't others?) the> > smallest amount we can get away with may, possibly, turn out to be the> > best for longevity.> > Then there's the PMID: 17292532> Eur Urol. 2007 Oct;52(4):1052-6. Epub 2007 Feb 5.> Dietary zinc and prostate cancer risk: a case-control study from Italy.> > Gallus S, Foschi R, Negri E, Talamini R, Franceschi S, Montella M, Ramazzotti V, > Tavani A, Dal Maso L, La Vecchia C.> > "CONCLUSIONS: In this large study we found a direct association between high zinc intake > and prostate cancer risk, particularly for advanced cancers. Our findings allow one to > exclude a favourable effect of zinc on prostate carcinogenesis."> > Thanks,> Todd>

[Guest guest]

If we need a lot of zinc we won't get it in plants.

I doubt we'll get much in oysters.

I can't believe a relationship between zinc and cancer unless overdosing supplements cause it.

Duke's lists:

Biological Activities (partial list)

Antialzheimeran Dosage: 50 mg/day; Reference: WER Anticoronary Dosage: 30 mg/day; Reference: SYN-X Antidiabetic Dosage: 30 mg/day; Reference: SYN-X Antiprostatitic Dosage: 50 mg/man/day/orl; Reference: PAM Antirheumatic Reference: DAS Immunosuppressant Dosage: 300 mg/day/6 wks/orl/man; Reference: M29 Spermigenic Dosage: 60 mg/day; Reference: WER Testosteronigenic Dosage: 60 mg/day; Reference: WER

TOZAL is ~56 mg (for ARMD) tested 15 yrs in AREDS study.

Strikes me, if these levels, 3x RDA, are required then we should have a much higher incidences.

Also there are large ethnic variations.

Regards

[ ] Re: Zinc and prostate cancerHi Todd:Thank you. And this one also:Zinc supplement use and risk of prostate cancer.

[Guest guest]

JW: who is this guy? I googled him and if it’s the same guy, he’s a botanist. A botanist studies plantlife. That doesn’t sound like much in the way of credentials.

From: jwwright <jwwright@...>

Reply-< >

Date: Fri, 29 Feb 2008 10:41:42 -0800

< >

Subject: Re: [ ] Re: Zinc and prostate cancer

If we need a lot of zinc we won't get it in plants.

I doubt we'll get much in oysters.

I can't believe a relationship between zinc and cancer unless overdosing supplements cause it.

Duke's lists:

Biological Activities (partial list)

Antialzheimeran <http://www.ars-grin.gov/cgi-bin/duke/chemical_activity.pl?Antialzheimeran> Dosage: 50 mg/day; Reference: WER <http://www.ars-grin.gov/cgi-bin/duke/refs.pl?+WER> Anticoronary <http://www.ars-grin.gov/cgi-bin/duke/chemical_activity.pl?Anticoronary> Dosage: 30 mg/day; Reference: SYN-X <http://www.ars-grin.gov/cgi-bin/duke/refs.pl?+SYN-X> Antidiabetic <http://www.ars-grin.gov/cgi-bin/duke/chemical_activity.pl?Antidiabetic> Dosage: 30 mg/day; Reference: SYN-X <http://www.ars-grin.gov/cgi-bin/duke/refs.pl?+SYN-X> Antiprostatitic <http://www.ars-grin.gov/cgi-bin/duke/chemical_activity.pl?Antiprostatitic> Dosage: 50 mg/man/day/orl; Reference: PAM <http://www.ars-grin.gov/cgi-bin/duke/refs.pl?+PAM> Antirheumatic <http://www.ars-grin.gov/cgi-bin/duke/chemical_activity.pl?Antirheumatic> Reference: DAS <http://www.ars-grin.gov/cgi-bin/duke/refs.pl?+DAS> Immunosuppressant <http://www.ars-grin.gov/cgi-bin/duke/chemical_activity.pl?Immunosuppressant> Dosage: 300 mg/day/6 wks/orl/man; Reference: M29 <http://www.ars-grin.gov/cgi-bin/duke/refs.pl?+M29> Spermigenic <http://www.ars-grin.gov/cgi-bin/duke/chemical_activity.pl?Spermigenic> Dosage: 60 mg/day; Reference: WER <http://www.ars-grin.gov/cgi-bin/duke/refs.pl?+WER> Testosteronigenic <http://www.ars-grin.gov/cgi-bin/duke/chemical_activity.pl?Testosteronigenic> Dosage: 60 mg/day; Reference: WER <http://www.ars-grin.gov/cgi-bin/duke/refs.pl?+WER>

TOZAL is ~56 mg (for ARMD) tested 15 yrs in AREDS study.

Strikes me, if these levels, 3x RDA, are required then we should have a much higher incidences.

Also there are large ethnic variations.

Regards

[ ] Re: Zinc and prostate cancer

Hi Todd:

Thank you. And this one also:

Zinc supplement use and risk of prostate cancer.

[Guest guest]

Does zinc supplementation or in the diet counter aging, aging symptoms, anyway? The below paper is pdf-availed. http://en.wikipedia.org/wiki/Fluorescent-activated_cell_sorting#Fluorescence-activated_cell_sorting (FACS) was used. Putics A, Vödrös D, Malavolta M, Mocchegiani E, Csermely P, Sõti C.Zinc supplementation boosts the stress response in the elderly: Hsp70 status is linked to zinc availability in peripheral lymphocytes.Exp Gerontol. 2008 Jan 15; [Epub ahead of print] PMID: 18304769 Chaperones and zinc are indispensable for proper immune function. All the zinc status, the immune function and the stress response decline during aging. Here we studied the effect of nutritional zinc and zinc homeostasis on the stress

response in healthy old subjects recruited during the ZincAge European Union project that either underwent or not a 48-day zinc supplementation. Inducible Hsp70 levels were determined at basal conditions as well as after heat shock in the CD3+ and CD3- subset of lymphocytes by a two-color FACS analysis. Short term zinc supplementation resulted in a marked increase in both basal as well as stress-induced Hsp70 levels in lymphocytes from healthy elderly donors with a higher impact on CD3+ cells. Heat inducibility showed a strong correlation with basal Hsp70 level, and both basal as well as stress-induced Hsp70 highly correlated with intracellular zinc availability. In conclusion, short term oral supplementation with zinc safely and efficiently induces the stress response in lymphocytes of old donors. The stress response may be a candidate pathway connecting zinc deficiency with aging and immunosenescence. Thus,

proper dietary zinc intake may emerge as a chaperone inducer and an anti-aging mechanism in the immune system. +++++++++++++++++++++++++++++++ ... Both a single heat shock as well as transgenic Hsp70 induces longevity (Tatar et al., 1997) ... ... Table 1. Age of the subjects and zinc status before and after zinc supplementation.================================================= Age (years) Plasma Zn (µM) Zn availability ---MFI at 37°C MFI at 43°C Ind. (fold)=================================================Before Zn suppl. 74.7±2.0 12.1±0.7 1.26±0.03After Zn

suppl. - 13.5±1.5 1.39±0.02P - 0.367 0.013================================================= Data (n = 7) were obtained as described in Subjects and methods and shown as mean±SEM. p values were calculated using the Student’s paired samples t-test. Ind., induced. MFI, mean fluorescence intensity. ... Table 2. Relationship between the zinc status and the stress response.================================================= Group (n) Plasma Zn (µM) Zn availability---Hsp70 status ---MFI at 37°C MFI at 43°C Ind. (fold)================================================= Low Zn (10) 11.8±0.5 1.21±0.02 9.4±1.1 26.5±4.8

2.7±0.4High Zn (10) 13.1±1.1 1.39±0.02 16.7±1.5 97.4±14.3 5.9±0.7P 0.068 < 0.0001 0.001 0.001 0.001================================================= Subjects were grouped according to their zinc availability (high Zn > 1.30 =/> low Zn). Data were obtained as described in Subjects and methods and shown as mean±SEM. Basal (37°C) and heat-induced Hsp70 (43°C) levels are indicated as the mean fluorescence intensity (MFI), Hsp70 inducibility (Ind.) is given as the 43°C/37°C ratio. p values were calculated using the Student’s independent samples t-test. MFI, mean fluorescence intensity. ... Discussion Loss of adaptation to stress is a hallmark of aging. A major molecular mechanism behind is a decrease in heat shock response, a fundamental cytoprotective and survival mechanism in several models (Sõti and Csermely, 2003; Arslan

et al., 2006), including human blood cells and extracellular chaperones of the elderly (Njemini et al., 2002; Rea et al., 2001; Singh et al., 2006). Since molecular chaperones are intimately involved in signaling and proliferation, a less robust stress response may not only cause limited survival, but may also contribute to the compromised reactivity of old lymphocytes to various inflammatory stimuli, a phenomenon called immune cell anergy (Pawelec, 2006). ... ... Stress tolerance, the adaptation to an environmental noxa depends on the robustness of the stress response, i.e. the inducibility of stress proteins by the heat shock transcription factor (Voellmy, 2004). Preconditioning (exposure to a mild stress, like hormesis [Verbeke et al., 2001; Rattan, 2004]) results in elevations in Hsp70 and other stress proteins, a more robust stress response and a better adaptation with implications in longevity. However,

large elevation in Hsp70 is only transient and the remaining protein level is insufficient to meet the increased demand during stress. To our knowledge, no molecular mechanism has been associated with a better mounting of the stress response after a previous/chronic mild stress. ... ... As a conclusion, we provided evidence that dietary zinc is a chaperone inducer and a major determinant of the stress response in human lymphocytes in the elderly. Since the stress response is a conserved and universal phenomenon, and the effect of zinc in vitro is fairly general, these findings may have wider implications in other bodily tissues as a possible anti aging mechanism. However, whether this is a proof of principle or a special exception will be a subject of future studies. -- Al Pater, alpater@...

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