Soy bad for Mice

[Guest guest]

I apologize if this has already been discussed.

Soy diet worsens heart disease in male mice -study

Wed Jan 4, 5:10 PM ET

WASHINGTON (Reuters) - Heart conditions became worse in

male mice carrying a genetic mutation for heart disease when

they were fed a soy diet, a study published on Wednesday

showed.

Male mice carrying the mutation for hypertrophic

cardiomyopathy or HCM, were severely affected by the soy diet,

showing enlarged heart muscles and eventual heart failure,

according to the University of Colorado at Boulder study

published in the Journal of Clinical Investigation.

HCM is the leading cause of death in young athletes and

affects about one in 500 people. Eighteen genes associated with

the disease have been identified, according to University of

Colorado professor Leinwand.

Soy foods and diet supplements are perceived to be a huge

health benefit to humans. Consumers spent an estimated $4.7

billion on them in 2005.

"We were shocked by the results," said Leinwand, noting

that when the mice in the study were switched to a diet of a

milk protein their condition improved markedly.

Female mice carrying the mutation for HCM were relatively

unaffected by the soy diet, according to the study. That led

the Colorado research team to believe that heart deterioration

in male mice was due at least in part to plant-based estrogens

in the soy food diet.

"To our knowledge this is the first report of significant

differences in cardiac muscle adaptation due to dietary

manipulation," researchers wrote.

Leinwand said: "I don't think normal, healthy people should

be alarmed by the results of this study.

"But we are seeing more cautionary reactions from the

medical community in recent years regarding the ingestion of

huge quantities of dietary supplements, including soy

phytoestrogens."

[Guest guest]

If anybody has the actual study, it would be nice to know just how much soy the mice ingested relative to the rest of their diet. Sometimes these studies are so skewed (example: equal to a few tons of soy per day in a human) as to be meaningless.

on 1/6/2006 8:21 AM, Dennis De Jarnette at positivedennis@... wrote:

I apologize if this has already been discussed.

Soy diet worsens heart disease in male mice -study

[Guest guest]

If anybody has the actual study, it would be nice to know just how much soy the mice ingested relative to the rest of their diet. Sometimes these studies are so skewed (example: equal to a few tons of soy per day in a human) as to be meaningless.

on 1/6/2006 8:21 AM, Dennis De Jarnette at positivedennis@... wrote:

I apologize if this has already been discussed.

Soy diet worsens heart disease in male mice -study