Decline in cognitive function

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No mention of carnosine.

There's a conflict of ginkgo with anticoagulants.

Rakel: Integrative Medicine, 1st ed., Copyright © 2003 Saunders

PREVENTION PRESCRIPTION

• Daily routine

• AM: Patients are counseled to awaken at or around sunrise and to take a 20- to 30-minute walk and practice meditation.

• Lunch: Patients should make lunch the main meal of the day.

• PM: Patients should practice meditation, eat a light supper, and go to bed no later than 10:30.

• Exercise: A brisk 20- to 30-minute early-morning walk is a good way to get started. This can be increased or supplemented, depending on the patient’s fitness level. Weight training should also be considered if possible.

• Stress management: Regular use of 2 or 3 breathing exercises and practice of basic meditation 10 to 30 minutes twice daily are recommended.

• Nutrition: Some guidelines are presented in Table 73–2 .

• Basic supplements, included as preventive measure

• Multivitamin dosage ranges

Vitamin E as mixed tocopherols: 400 to 800 IU per day

Vitamin C: 500 mg per day in divided doses

Vitamin A: 10,000 IU per day

Vitamin B1 : 50 mg per day

Vitamin B6 : 50 mg per day

Vitamin B12 : 100 to 1000 µg per day

Folate: 400 µg per day

• Coenzyme Q10: 30 to 100 mg per day

• Advanced supplements, to be considered in patients who have some memory dysfunction

• Phosphatidyl serine: prevention: 100 mg per day; therapeutic: 100 mg 3 times a day

• Acetyl L-carnitine: prevention: 250 to 500 mg per day; therapeutic: 1500 to 3000 mg per day

• Possible synergistic effect of these supplements used in combination

• Botanicals

• Ginkgo biloba: prevention: 60 to 120 mg per day; therapeutic: 120 to 240 mg per day

• Ginseng: variable

• Huperzine A: prevention: 50 to 100 µg per day; therapeutic: 100 to 300 µg per day

TABLE 73-2 -- Nutritional Recommendations for Memory Protection

• Reduce total caloric consumption (2000–3000 calories per day)

• Reduce saturated fats; favor monounsaturated fats (olive oil)

• Avoid partially hydrogenated vegetable oils

• Increase omega-3 essential fatty acids (fish, nuts, flaxseed)

• Favor whole cereals and grains

• Increase fruit and vegetable consumption

• Reduce meat intake

• Avoid artificial sweeteners, additives, and preservatives