Re: One More For The Whole

[Guest guest]

How about someone FINALLY gets around to doing a study of the

relative benefit of: A) whole grains; refined grains, and C)

BRAN AND GERM WITHOUT THE STARCH?

Naturally, without the starch caloric intake would be appreciably

less and most of us here believe that alone would provide huge

benefits.

Sigh!

Rodney.

--- In , " Jeff Novick " <jnovick@...>

wrote:

>

> American Journal of Clinical Nutrition, Vol. 83, No. 1, 124-131,

January 2006

> © 2006 American Society for Clinical Nutrition

>

> ________________________________

>

>

> ORIGINAL RESEARCH COMMUNICATION

>

>

> Whole-grain intake is inversely associated with the metabolic

syndrome and mortality in older adults1,2,3

>

> Nadine R Sahyoun, F Jacques, Xinli L Zhang, Wenyen and

Nicola M McKeown

>

> 1 From the Department of Nutrition and Food Science, University of

land, College Park, MD (NRS and XLZ); the Mayer US

Department of Agriculture Human Nutrition Research Center on Aging,

Tufts University, Boston, MA (PFJ and NMM); and the Center for

Nutrition Policy and Promotion, US Department of Agriculture,

Arlington, VA (WJ)

>

> Background: Whole-grain intake has been inversely associated with

the metabolic syndrome in middle-aged populations, but the

association has not been investigated in older adults. The metabolic

consequence of consuming high whole-grain diets may differ in elderly

persons, who are prone to greater insulin resistance and impaired

glucose tolerance.

>

> Objective: The aim of the present study was to examine the cross-

sectional association between whole- and refined-grain intake,

cardiovascular disease risk factors, prevalence of the metabolic

syndrome, and the incidence of cardiovascular disease mortality in

the same cohort of older adults.

>

> Design: The nutritional status of 535 healthy persons aged 60-98 y

was determined from 1981 to 1984. The subjects kept a 3-d food record

and had their blood tested for metabolic risk factors. The metabolic

syndrome was defined based on criteria set by the third report of the

National Cholesterol Education Program. The vital status of the

subjects was identified in October 1995.

>

> Results: The results showed a significant inverse trend between

whole-grain intake and the metabolic syndrome (P for trend = 0.005)

and mortality from cardiovascular disease (P for trend = 0.04),

independent of demographic, lifestyle, and dietary factors. Fasting

glucose concentrations and body mass index decreased across

increasing quartile categories of whole-grain intake (P for trend =

0.01 and 0.03, respectively), independent of confounders, whereas

intake of refined grain was positively associated with higher fasting

glucose concentrations (P for trend = 0.04) and a higher prevalence

of the metabolic syndrome (P for trend = 0.01).

>

> Conclusion: Whole-grain intake is a modifiable dietary risk factor,

and older and young adults should be encouraged to increase their

daily intake to ?3 servings/d.

>

[Guest guest]

How about someone FINALLY gets around to doing a study of the

relative benefit of: A) whole grains; refined grains, and C)

BRAN AND GERM WITHOUT THE STARCH?

Naturally, without the starch caloric intake would be appreciably

less and most of us here believe that alone would provide huge

benefits.

Sigh!

Rodney.

--- In , " Jeff Novick " <jnovick@...>

wrote:

>

> American Journal of Clinical Nutrition, Vol. 83, No. 1, 124-131,

January 2006

> © 2006 American Society for Clinical Nutrition

>

> ________________________________

>

>

> ORIGINAL RESEARCH COMMUNICATION

>

>

> Whole-grain intake is inversely associated with the metabolic

syndrome and mortality in older adults1,2,3

>

> Nadine R Sahyoun, F Jacques, Xinli L Zhang, Wenyen and

Nicola M McKeown

>

> 1 From the Department of Nutrition and Food Science, University of

land, College Park, MD (NRS and XLZ); the Mayer US

Department of Agriculture Human Nutrition Research Center on Aging,

Tufts University, Boston, MA (PFJ and NMM); and the Center for

Nutrition Policy and Promotion, US Department of Agriculture,

Arlington, VA (WJ)

>

> Background: Whole-grain intake has been inversely associated with

the metabolic syndrome in middle-aged populations, but the

association has not been investigated in older adults. The metabolic

consequence of consuming high whole-grain diets may differ in elderly

persons, who are prone to greater insulin resistance and impaired

glucose tolerance.

>

> Objective: The aim of the present study was to examine the cross-

sectional association between whole- and refined-grain intake,

cardiovascular disease risk factors, prevalence of the metabolic

syndrome, and the incidence of cardiovascular disease mortality in

the same cohort of older adults.

>

> Design: The nutritional status of 535 healthy persons aged 60-98 y

was determined from 1981 to 1984. The subjects kept a 3-d food record

and had their blood tested for metabolic risk factors. The metabolic

syndrome was defined based on criteria set by the third report of the

National Cholesterol Education Program. The vital status of the

subjects was identified in October 1995.

>

> Results: The results showed a significant inverse trend between

whole-grain intake and the metabolic syndrome (P for trend = 0.005)

and mortality from cardiovascular disease (P for trend = 0.04),

independent of demographic, lifestyle, and dietary factors. Fasting

glucose concentrations and body mass index decreased across

increasing quartile categories of whole-grain intake (P for trend =

0.01 and 0.03, respectively), independent of confounders, whereas

intake of refined grain was positively associated with higher fasting

glucose concentrations (P for trend = 0.04) and a higher prevalence

of the metabolic syndrome (P for trend = 0.01).

>

> Conclusion: Whole-grain intake is a modifiable dietary risk factor,

and older and young adults should be encouraged to increase their

daily intake to ?3 servings/d.

>

[Guest guest]

It's nice to have the P for Trend numbers, but it would be more

interesting to see what the associated risk/benefits were and what the

regions of associated errors were.

If the trend is rock solid but shallow (1.1 associated risk for eating

processed grains, 0.95 [reduced] risk when consuming whole grains), then

this admonition is less compelling.

Maco

At 07:28 AM 2/7/2006, you wrote:

American Journal of Clinical

Nutrition, Vol. 83, No. 1, 124-131, January 2006

© 2006 American Society for Clinical Nutrition

________________________________

ORIGINAL RESEARCH COMMUNICATION

Whole-grain intake is inversely associated with the metabolic syndrome

and mortality in older adults1,2,3

Nadine R Sahyoun, F Jacques, Xinli L Zhang, Wenyen and Nicola M

McKeown

1 From the Department of Nutrition and Food Science, University of

land, College Park, MD (NRS and XLZ); the Mayer US Department of

Agriculture Human Nutrition Research Center on Aging, Tufts University,

Boston, MA (PFJ and NMM); and the Center for Nutrition Policy and

Promotion, US Department of Agriculture, Arlington, VA (WJ)

Background: Whole-grain intake has been inversely associated with the

metabolic syndrome in middle-aged populations, but the association has

not been investigated in older adults. The metabolic consequence of

consuming high whole-grain diets may differ in elderly persons, who are

prone to greater insulin resistance and impaired glucose tolerance.

Objective: The aim of the present study was to examine the

cross-sectional association between whole- and refined-grain intake,

cardiovascular disease risk factors, prevalence of the metabolic

syndrome, and the incidence of cardiovascular disease mortality in the

same cohort of older adults.

Design: The nutritional status of 535 healthy persons aged 60-98 y was

determined from 1981 to 1984. The subjects kept a 3-d food record and had

their blood tested for metabolic risk factors. The metabolic syndrome was

defined based on criteria set by the third report of the National

Cholesterol Education Program. The vital status of the subjects was

identified in October 1995.

Results: The results showed a significant inverse trend between

whole-grain intake and the metabolic syndrome (P for trend = 0.005) and

mortality from cardiovascular disease (P for trend = 0.04), independent

of demographic, lifestyle, and dietary factors. Fasting glucose

concentrations and body mass index decreased across increasing quartile

categories of whole-grain intake (P for trend = 0.01 and 0.03,

respectively), independent of confounders, whereas intake of refined

grain was positively associated with higher fasting glucose

concentrations (P for trend = 0.04) and a higher prevalence of the

metabolic syndrome (P for trend = 0.01).

Conclusion: Whole-grain intake is a modifiable dietary risk factor, and

older and young adults should be encouraged to increase their daily

intake to ?3 servings/d.

[Guest guest]

It's nice to have the P for Trend numbers, but it would be more

interesting to see what the associated risk/benefits were and what the

regions of associated errors were.

If the trend is rock solid but shallow (1.1 associated risk for eating

processed grains, 0.95 [reduced] risk when consuming whole grains), then

this admonition is less compelling.

Maco

At 07:28 AM 2/7/2006, you wrote:

American Journal of Clinical

Nutrition, Vol. 83, No. 1, 124-131, January 2006

© 2006 American Society for Clinical Nutrition

________________________________

ORIGINAL RESEARCH COMMUNICATION

Whole-grain intake is inversely associated with the metabolic syndrome

and mortality in older adults1,2,3

Nadine R Sahyoun, F Jacques, Xinli L Zhang, Wenyen and Nicola M

McKeown

1 From the Department of Nutrition and Food Science, University of

land, College Park, MD (NRS and XLZ); the Mayer US Department of

Agriculture Human Nutrition Research Center on Aging, Tufts University,

Boston, MA (PFJ and NMM); and the Center for Nutrition Policy and

Promotion, US Department of Agriculture, Arlington, VA (WJ)

Background: Whole-grain intake has been inversely associated with the

metabolic syndrome in middle-aged populations, but the association has

not been investigated in older adults. The metabolic consequence of

consuming high whole-grain diets may differ in elderly persons, who are

prone to greater insulin resistance and impaired glucose tolerance.

Objective: The aim of the present study was to examine the

cross-sectional association between whole- and refined-grain intake,

cardiovascular disease risk factors, prevalence of the metabolic

syndrome, and the incidence of cardiovascular disease mortality in the

same cohort of older adults.

Design: The nutritional status of 535 healthy persons aged 60-98 y was

determined from 1981 to 1984. The subjects kept a 3-d food record and had

their blood tested for metabolic risk factors. The metabolic syndrome was

defined based on criteria set by the third report of the National

Cholesterol Education Program. The vital status of the subjects was

identified in October 1995.

Results: The results showed a significant inverse trend between

whole-grain intake and the metabolic syndrome (P for trend = 0.005) and

mortality from cardiovascular disease (P for trend = 0.04), independent

of demographic, lifestyle, and dietary factors. Fasting glucose

concentrations and body mass index decreased across increasing quartile

categories of whole-grain intake (P for trend = 0.01 and 0.03,

respectively), independent of confounders, whereas intake of refined

grain was positively associated with higher fasting glucose

concentrations (P for trend = 0.04) and a higher prevalence of the

metabolic syndrome (P for trend = 0.01).

Conclusion: Whole-grain intake is a modifiable dietary risk factor, and

older and young adults should be encouraged to increase their daily

intake to ?3 servings/d.

[Guest guest]

Rodney,

This is only 2006. You'll have to wait until 2035.

medical? "science" does things slowly.

With any luck we'll be asking the same questions then, as we do now.

My doc does not know why I can't get rid of a few # of excess fat and she smiles that I would want to, because 65% of her patients are obese as in obbeeesee.

She perfectly content with my 180 - 185 #. So am I - perfectly content with my doc.

You just need to get the right doc.

Relax, if you don't want to eat starch, it's ok. the human body is an omnivore - we can eat anything that doesn't eat us first.

Assuming you eat just the bran and germ, you still get some starch, cause they can't quite get all of it off the bran. I bot some wheat bran once in a "health food" store and it looked like the brown stuff you'd shave off wheat kernels. The first question I asked was "why?". Who decided to go to that much trouble - to make white flour - WHY? The germ I can understand - it practically falls off and it's the first part to spoil. Does anyone know we can just cook whole grain wheat kernels in the microwave? Just buy a 100# bag and scoop out some. We don't need anyone to modify it and put it in boxes showing blueberries (which aren't in there).

Bran was pretty good cooked like a hot cereal. But I don't eat it any more and I don't remember exactly why. It wasn't that much fun I guess.

I do eat a slice or 2 of brown bread, mostly because I need the energy and it's there.

It doesn't bother my gut and it wraps around other stuff. So I can see the usefulness of a bread, but gee, if I only eat 1800 kcals, why does it matter so much?

I mean I'm not going to base my existence on some silly study article - you now how that goes - some guy working his PhD needs to show something for the grant, so he writes up something he knows about. Maybe something his advisor/mentor gives him?

Americans eat a LOT of wheat and it's mostly white, and we have a LOT of centenarians.

ly, I don't believe any food is inversely related to metabolic syndrome.

There's lotsa people that eat wheat that don't have it. Gotta study the whole set.

Regards.

[ ] Re: One More For The "Whole"

How about someone FINALLY gets around to doing a study of the relative benefit of: A) whole grains; refined grains, and C) BRAN AND GERM WITHOUT THE STARCH?Naturally, without the starch caloric intake would be appreciably less and most of us here believe that alone would provide huge benefits.Sigh!Rodney.>> American Journal of Clinical Nutrition, Vol. 83, No. 1, 124-131, January 2006> © 2006 American Society for Clinical Nutrition > > ________________________________> > > ORIGINAL RESEARCH COMMUNICATION> > > Whole-grain intake is inversely associated with the metabolic syndrome and mortality in older adults1,2,3 > > Nadine R Sahyoun, F Jacques, Xinli L Zhang, Wenyen and Nicola M McKeown > > 1 From the Department of Nutrition and Food Science, University of land, College Park, MD (NRS and XLZ); the Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA (PFJ and NMM); and the Center for Nutrition Policy and Promotion, US Department of Agriculture, Arlington, VA (WJ) > > Background: Whole-grain intake has been inversely associated with the metabolic syndrome in middle-aged populations, but the association has not been investigated in older adults. The metabolic consequence of consuming high whole-grain diets may differ in elderly persons, who are prone to greater insulin resistance and impaired glucose tolerance. > > Objective: The aim of the present study was to examine the cross-sectional association between whole- and refined-grain intake, cardiovascular disease risk factors, prevalence of the metabolic syndrome, and the incidence of cardiovascular disease mortality in the same cohort of older adults. > > Design: The nutritional status of 535 healthy persons aged 60-98 y was determined from 1981 to 1984. The subjects kept a 3-d food record and had their blood tested for metabolic risk factors. The metabolic syndrome was defined based on criteria set by the third report of the National Cholesterol Education Program. The vital status of the subjects was identified in October 1995. > > Results: The results showed a significant inverse trend between whole-grain intake and the metabolic syndrome (P for trend = 0.005) and mortality from cardiovascular disease (P for trend = 0.04), independent of demographic, lifestyle, and dietary factors. Fasting glucose concentrations and body mass index decreased across increasing quartile categories of whole-grain intake (P for trend = 0.01 and 0.03, respectively), independent of confounders, whereas intake of refined grain was positively associated with higher fasting glucose concentrations (P for trend = 0.04) and a higher prevalence of the metabolic syndrome (P for trend = 0.01). > > Conclusion: Whole-grain intake is a modifiable dietary risk factor, and older and young adults should be encouraged to increase their daily intake to ?3 servings/d.>

[Guest guest]

Rodney,

This is only 2006. You'll have to wait until 2035.

medical? "science" does things slowly.

With any luck we'll be asking the same questions then, as we do now.

My doc does not know why I can't get rid of a few # of excess fat and she smiles that I would want to, because 65% of her patients are obese as in obbeeesee.

She perfectly content with my 180 - 185 #. So am I - perfectly content with my doc.

You just need to get the right doc.

Relax, if you don't want to eat starch, it's ok. the human body is an omnivore - we can eat anything that doesn't eat us first.

Assuming you eat just the bran and germ, you still get some starch, cause they can't quite get all of it off the bran. I bot some wheat bran once in a "health food" store and it looked like the brown stuff you'd shave off wheat kernels. The first question I asked was "why?". Who decided to go to that much trouble - to make white flour - WHY? The germ I can understand - it practically falls off and it's the first part to spoil. Does anyone know we can just cook whole grain wheat kernels in the microwave? Just buy a 100# bag and scoop out some. We don't need anyone to modify it and put it in boxes showing blueberries (which aren't in there).

Bran was pretty good cooked like a hot cereal. But I don't eat it any more and I don't remember exactly why. It wasn't that much fun I guess.

I do eat a slice or 2 of brown bread, mostly because I need the energy and it's there.

It doesn't bother my gut and it wraps around other stuff. So I can see the usefulness of a bread, but gee, if I only eat 1800 kcals, why does it matter so much?

I mean I'm not going to base my existence on some silly study article - you now how that goes - some guy working his PhD needs to show something for the grant, so he writes up something he knows about. Maybe something his advisor/mentor gives him?

Americans eat a LOT of wheat and it's mostly white, and we have a LOT of centenarians.

ly, I don't believe any food is inversely related to metabolic syndrome.

There's lotsa people that eat wheat that don't have it. Gotta study the whole set.

Regards.

[ ] Re: One More For The "Whole"

How about someone FINALLY gets around to doing a study of the relative benefit of: A) whole grains; refined grains, and C) BRAN AND GERM WITHOUT THE STARCH?Naturally, without the starch caloric intake would be appreciably less and most of us here believe that alone would provide huge benefits.Sigh!Rodney.>> American Journal of Clinical Nutrition, Vol. 83, No. 1, 124-131, January 2006> © 2006 American Society for Clinical Nutrition > > ________________________________> > > ORIGINAL RESEARCH COMMUNICATION> > > Whole-grain intake is inversely associated with the metabolic syndrome and mortality in older adults1,2,3 > > Nadine R Sahyoun, F Jacques, Xinli L Zhang, Wenyen and Nicola M McKeown > > 1 From the Department of Nutrition and Food Science, University of land, College Park, MD (NRS and XLZ); the Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA (PFJ and NMM); and the Center for Nutrition Policy and Promotion, US Department of Agriculture, Arlington, VA (WJ) > > Background: Whole-grain intake has been inversely associated with the metabolic syndrome in middle-aged populations, but the association has not been investigated in older adults. The metabolic consequence of consuming high whole-grain diets may differ in elderly persons, who are prone to greater insulin resistance and impaired glucose tolerance. > > Objective: The aim of the present study was to examine the cross-sectional association between whole- and refined-grain intake, cardiovascular disease risk factors, prevalence of the metabolic syndrome, and the incidence of cardiovascular disease mortality in the same cohort of older adults. > > Design: The nutritional status of 535 healthy persons aged 60-98 y was determined from 1981 to 1984. The subjects kept a 3-d food record and had their blood tested for metabolic risk factors. The metabolic syndrome was defined based on criteria set by the third report of the National Cholesterol Education Program. The vital status of the subjects was identified in October 1995. > > Results: The results showed a significant inverse trend between whole-grain intake and the metabolic syndrome (P for trend = 0.005) and mortality from cardiovascular disease (P for trend = 0.04), independent of demographic, lifestyle, and dietary factors. Fasting glucose concentrations and body mass index decreased across increasing quartile categories of whole-grain intake (P for trend = 0.01 and 0.03, respectively), independent of confounders, whereas intake of refined grain was positively associated with higher fasting glucose concentrations (P for trend = 0.04) and a higher prevalence of the metabolic syndrome (P for trend = 0.01). > > Conclusion: Whole-grain intake is a modifiable dietary risk factor, and older and young adults should be encouraged to increase their daily intake to ?3 servings/d.>

[Guest guest]

The difficulty that I have with such studies may be that they overlook all

confounders. Whole grain intake was inversely related to refined grain intake,

for

example.

Here are the data from the paper, the pdf of which is available.

Mortality and intake of whole and refined grains

CVD was the cause of death in 89 subjects. A significant inverse trend was

observed

between whole-grain intake and mortality from CVD, even after control for

demographic and lifestyle factors (P for trend = 0.04). The risk of CVD death

for

the subjects in the highest quartile of whole-grain intake was significantly

lower

than for those in the lowest quartile of whole-grain intake [relative risk (RR):

0.48; CI: 0.25, 0.96] (Figure 1). No significant associations were found between

intake of whole grain and all cause mortality (P for trend = 0.65; data not

shown).

Compared with the lowest quartile of whole-grain intake, RRs (95% CIs) for

quartiles

2, 3, and 4, were 1.08 (0.71, 1.66), 1.24(0.83, 1.86), and 0.82 (0.52, 1.28),

respectively. No significant associations were found between intakes of refined

grains and all cause and CVD mortalities (P for trend = 0.69 and 0.41,

respectively;

data not shown).

FIGURE 1. Association between whole-grain intake quartile and cardiovascular

disease

(CVD) mortality. proportional regression analysis models were used to

examine

the association between mortality from CVD and whole-grain intake quartile (the

referent category was the lowest quartile). The model is adjusted for age, sex,

ethnicity, educational attainment, marital status, smoking, alcohol intake,

exercise, BMI, energy intake, percentage saturated fatty acid intake, history of

heart disease, and use of antihypertensive or lipid-lowering medication. Data

are

relative risks (RRs) and 95% CIs. P for trend = 0.04.

--- Maco <mstewart@...> wrote:

-------------------------------

It's nice to have the P for Trend numbers, but it would be moreinteresting to

see

what the associated risk/benefits were and what theregions of associated errors

were.

If the trend is rock solid but shallow (1.1 associated risk for eatingprocessed

grains, 0.95 [reduced] risk when consuming whole grains), thenthis admonition is

less compelling.

Sahyoun NR, Jacques PF, Zhang XL, W, McKeown NM.

Whole-grain intake is inversely associated with the metabolic syndrome and

mortality

in older adults.

Am J Clin Nutr. 2006 Jan;83(1):124-31.

PMID: 16400060

-- Al Pater, PhD; email: old542000@...

__________________________________________________

[Guest guest]

The difficulty that I have with such studies may be that they overlook all

confounders. Whole grain intake was inversely related to refined grain intake,

for

example.

Here are the data from the paper, the pdf of which is available.

Mortality and intake of whole and refined grains

CVD was the cause of death in 89 subjects. A significant inverse trend was

observed

between whole-grain intake and mortality from CVD, even after control for

demographic and lifestyle factors (P for trend = 0.04). The risk of CVD death

for

the subjects in the highest quartile of whole-grain intake was significantly

lower

than for those in the lowest quartile of whole-grain intake [relative risk (RR):

0.48; CI: 0.25, 0.96] (Figure 1). No significant associations were found between

intake of whole grain and all cause mortality (P for trend = 0.65; data not

shown).

Compared with the lowest quartile of whole-grain intake, RRs (95% CIs) for

quartiles

2, 3, and 4, were 1.08 (0.71, 1.66), 1.24(0.83, 1.86), and 0.82 (0.52, 1.28),

respectively. No significant associations were found between intakes of refined

grains and all cause and CVD mortalities (P for trend = 0.69 and 0.41,

respectively;

data not shown).

FIGURE 1. Association between whole-grain intake quartile and cardiovascular

disease

(CVD) mortality. proportional regression analysis models were used to

examine

the association between mortality from CVD and whole-grain intake quartile (the

referent category was the lowest quartile). The model is adjusted for age, sex,

ethnicity, educational attainment, marital status, smoking, alcohol intake,

exercise, BMI, energy intake, percentage saturated fatty acid intake, history of

heart disease, and use of antihypertensive or lipid-lowering medication. Data

are

relative risks (RRs) and 95% CIs. P for trend = 0.04.

--- Maco <mstewart@...> wrote:

-------------------------------

It's nice to have the P for Trend numbers, but it would be moreinteresting to

see

what the associated risk/benefits were and what theregions of associated errors

were.

If the trend is rock solid but shallow (1.1 associated risk for eatingprocessed

grains, 0.95 [reduced] risk when consuming whole grains), thenthis admonition is

less compelling.

Sahyoun NR, Jacques PF, Zhang XL, W, McKeown NM.

Whole-grain intake is inversely associated with the metabolic syndrome and

mortality

in older adults.

Am J Clin Nutr. 2006 Jan;83(1):124-31.

PMID: 16400060

-- Al Pater, PhD; email: old542000@...

__________________________________________________