Re: Daily tomato juice lowers inflammation markers 34%

[Guest guest]

Hi Dave:

Purely a stab in the dark on my part. But here is my guess about

" Lyc-o-Mato " ..............

I believe the skin of tomato contains more lycopene than the rest of

it. Often the skins are discarded when canned tomatoes are processed.

My guess is that 'Lyc-o-Mato' is produced by adding ground up

discarded skins to regular tomato juice. Gets rid of a by-product it

would otherwise cost money to dispose of, and enhances the nutrient

content of the juice ..... perhaps.

Rodney.

>

> Hi All:

>

> Italian researchers claim a daily glass of tomato juice could lower

> inflammation by over 30 per cent. In the study they used " Lyc-o-Mato "

> branded juice. Not sure if this juice is supposed to have higher

> carotenoids (like lycopene) than regular tomato juice or not.

>

> Seems to me drinking any tomato juice would be cheap insurance, as I

> think an 8 ounce glass is only about 50 calories.

>

> Dave

>

> ++++++++++++++++++++++++

>

> link and full text:

>

>

http://www.nutraingredients-usa.com/news/ng.asp?n=66846 & m=1NIU404 & c=lqeudkujayvv\

lpc

>

> Tomato juice could lower inflammation

>

> 4/4/2006- Italian researchers have reported that a daily glass of

> tomato juice could lower markers for inflammation by over 30 per cent,

> but has no effect on the immune system, adding to the debate as to

> whether carotenoids can boost immune function.

>

> Researchers from the University of the Milan found that a daily intake

> of the commercial tomato drink, Lyc-o-Mato was linked to a drop in the

> inflammatory mediator TNF-alpha by 34 per cent after six weeks of

> supplementation of a normal diet.

>

> Inflammation is linked to hardening of the walls of the arteries

> (atherosclerosis), and cardiovascular disease (CVD) – the cause of

> almost 50 per cent of deaths in Europe.

>

> Tomato extract contains a mix of potent antioxidants including

> lycopene, beta-carotene, vitamin E and various other phytonutrients.

> The extract has been associated with lowering blood pressure and

> boosting immune function, although this last claim is hotly disputed

> by conflicting results.

>

> " We report modest effects of the regular uptake of a tomato drink

> providing small amounts of carotenoids on the production of

> inflammatory mediators such as TNF-alpha in young healthy volunteers, "

> said lead author Patrizio Riso in the Journal of Agricultural and Food

> Chemistry (Vol. 54, pp. 2563-2566).

>

> The placebo-controlled, double-blind crossover trial divided 26 young

> healthy volunteers into two groups. Group one (N=13) was assigned to

> the sequence placebo/wash-out/Lyc-o-Mato, while the second group was

> assigned the inverse, Lyc-o-Mato/washout/placebo. People with kidney,

> heart, and liver diseases, and pregnant women taking supplements, were

> excluded from the study

>

> The mediator for inflammation, TNF-alpha, and markers of immune

> response, the cytokine IFN-gamma, were measured by blood sample

> analysis. White blood cell DNA damage was also quantified.

>

> After 26 days of either placebo or Lyc-o-Mato, the researchers found

> that TNF-alpha levels were significantly decreased by 34 per cent

> after consumption of the tomato drink. No changes were observed after

> placebo.

>

> The authors suggest that the effects of the tomato juice are due to

> one of several mechanisms, including altering cytokine production, the

> boosting of T-lymphocyte function, or the inhibition of arachidonic

> acid metabolism that is catalysed by free radicals.

>

> However, the appropriate compounds to support the latter mechanism

> were not found in an analysis of the volunteers urine.

>

> Interestingly, levels of IFN-gamma increased after the placebo drink,

> a result that could not be explained by the researchers since the

> placebo drink was formulated to appear and taste like the tomato drink

> but did not contain any bioactive compounds. IFN-gamma levels after

> consuming the tomato drink were unchanged, indicating that the tomato

> drink had no effect on the immune system.

>

> " These data add to the controversy of whether lycopene, and the other

> carotenoids, affect immune response, " said Riso.

>

> DNA damage was also insignificant in both groups, a result that could

> have been due to the young, healthy subjects having little DNA damage

> at baseline.

>

> These results differ somewhat from other studies that have focused on

> predominantly elderly populations. Some have reported increases in

> immune function, and other have reported increases in inflammation

> mediators due to the tomato juice.

>

> " Further intervention trials will follow in subjects with low

> carotenoid status and/or compromised immune system, " said Riso.

>

> Israeli-company LycoRed, producers of Lyc-o-Mato, supplied the tomato

> juice drink.

>

[Guest guest]

Hi Dave:

Purely a stab in the dark on my part. But here is my guess about

" Lyc-o-Mato " ..............

I believe the skin of tomato contains more lycopene than the rest of

it. Often the skins are discarded when canned tomatoes are processed.

My guess is that 'Lyc-o-Mato' is produced by adding ground up

discarded skins to regular tomato juice. Gets rid of a by-product it

would otherwise cost money to dispose of, and enhances the nutrient

content of the juice ..... perhaps.

Rodney.

>

> Hi All:

>

> Italian researchers claim a daily glass of tomato juice could lower

> inflammation by over 30 per cent. In the study they used " Lyc-o-Mato "

> branded juice. Not sure if this juice is supposed to have higher

> carotenoids (like lycopene) than regular tomato juice or not.

>

> Seems to me drinking any tomato juice would be cheap insurance, as I

> think an 8 ounce glass is only about 50 calories.

>

> Dave

>

> ++++++++++++++++++++++++

>

> link and full text:

>

>

http://www.nutraingredients-usa.com/news/ng.asp?n=66846 & m=1NIU404 & c=lqeudkujayvv\

lpc

>

> Tomato juice could lower inflammation

>

> 4/4/2006- Italian researchers have reported that a daily glass of

> tomato juice could lower markers for inflammation by over 30 per cent,

> but has no effect on the immune system, adding to the debate as to

> whether carotenoids can boost immune function.

>

> Researchers from the University of the Milan found that a daily intake

> of the commercial tomato drink, Lyc-o-Mato was linked to a drop in the

> inflammatory mediator TNF-alpha by 34 per cent after six weeks of

> supplementation of a normal diet.

>

> Inflammation is linked to hardening of the walls of the arteries

> (atherosclerosis), and cardiovascular disease (CVD) – the cause of

> almost 50 per cent of deaths in Europe.

>

> Tomato extract contains a mix of potent antioxidants including

> lycopene, beta-carotene, vitamin E and various other phytonutrients.

> The extract has been associated with lowering blood pressure and

> boosting immune function, although this last claim is hotly disputed

> by conflicting results.

>

> " We report modest effects of the regular uptake of a tomato drink

> providing small amounts of carotenoids on the production of

> inflammatory mediators such as TNF-alpha in young healthy volunteers, "

> said lead author Patrizio Riso in the Journal of Agricultural and Food

> Chemistry (Vol. 54, pp. 2563-2566).

>

> The placebo-controlled, double-blind crossover trial divided 26 young

> healthy volunteers into two groups. Group one (N=13) was assigned to

> the sequence placebo/wash-out/Lyc-o-Mato, while the second group was

> assigned the inverse, Lyc-o-Mato/washout/placebo. People with kidney,

> heart, and liver diseases, and pregnant women taking supplements, were

> excluded from the study

>

> The mediator for inflammation, TNF-alpha, and markers of immune

> response, the cytokine IFN-gamma, were measured by blood sample

> analysis. White blood cell DNA damage was also quantified.

>

> After 26 days of either placebo or Lyc-o-Mato, the researchers found

> that TNF-alpha levels were significantly decreased by 34 per cent

> after consumption of the tomato drink. No changes were observed after

> placebo.

>

> The authors suggest that the effects of the tomato juice are due to

> one of several mechanisms, including altering cytokine production, the

> boosting of T-lymphocyte function, or the inhibition of arachidonic

> acid metabolism that is catalysed by free radicals.

>

> However, the appropriate compounds to support the latter mechanism

> were not found in an analysis of the volunteers urine.

>

> Interestingly, levels of IFN-gamma increased after the placebo drink,

> a result that could not be explained by the researchers since the

> placebo drink was formulated to appear and taste like the tomato drink

> but did not contain any bioactive compounds. IFN-gamma levels after

> consuming the tomato drink were unchanged, indicating that the tomato

> drink had no effect on the immune system.

>

> " These data add to the controversy of whether lycopene, and the other

> carotenoids, affect immune response, " said Riso.

>

> DNA damage was also insignificant in both groups, a result that could

> have been due to the young, healthy subjects having little DNA damage

> at baseline.

>

> These results differ somewhat from other studies that have focused on

> predominantly elderly populations. Some have reported increases in

> immune function, and other have reported increases in inflammation

> mediators due to the tomato juice.

>

> " Further intervention trials will follow in subjects with low

> carotenoid status and/or compromised immune system, " said Riso.

>

> Israeli-company LycoRed, producers of Lyc-o-Mato, supplied the tomato

> juice drink.

>