Guest guest Posted October 12, 2005 Report Share Posted October 12, 2005 Hi All, See the pdf-available below. 10 Oct 2005 22:27:36 -0000 Subject: [ ] Eat fish once a week Two studies show that eating fish once a week may delay dementia, while obesity doubles the risk. http://news./s/nm/20051010/hl_nm/dementia_dc EARLY RELEASE Fish Consumption and Cognitive Decline -------------------------------------------------------------------------------- and colleagues studied whether dietary intake of fish and the & #969;-3 fatty acids associated with lower risk of Alzheimer disease and stroke also are associated with slower cognitive decline. Compared with a decline rate in score of -0.100 SU/y among persons who consumed fish less than weekly, the rate was 10% slower (-0.090 SU/y) among persons who consumed 1 fish meal per week and 13% slower (-0.088 SU/y) among persons who consumed 2+ fish meals per week. FREE ARTICLE http://archneur.ama-assn.org.qe2a-proxy.mun.ca/cgi/reprint/62.12.noc50161v1 Fish Consumption and Cognitive Decline With Age in a Large Community Study Martha Clare , ScD; Denis A. , MD; C. Tangney, PhD; L. Bienias, ScD; S. , PhD Arch Neurol. 2005;62:(doi:10.1001/archneur.62.12.noc50161). ABSTRACT Background Dietary intake of fish and the -3 fatty acids have been associated with lower risk of Alzheimer disease and stroke. Objective To examine whether intakes of fish and the -3 fatty acids protect against age-related cognitive decline. Design Prospective cohort study. Setting Geographically defined Chicago, Ill, community. Participants Residents, 65 years and older, who participated in the Chicago Health and Aging Project. Main Outcome Measure Change in a global cognitive score estimated from mixed models. The global score was computed by summing scores of 4 standardized tests. In-home cognitive assessments were performed 3 times over 6 years of follow-up. Results Cognitive scores declined on average at a rate of 0.04 standardized units per year (SU/y). Fish intake was associated with a slower rate of cognitive decline in mixed models adjusted for age, sex, race, education, cognitive activity, physical activity, alcohol consumption, and total energy intake. Compared with a decline rate in score of –0.100 SU/y among persons who consumed fish less than weekly, the rate was 10% slower (–0.090 SU/y) among persons who consumed 1 fish meal per week and 13% slower (–0.088 SU/y) among persons who consumed 2 or more fish meals per week. The fish association was not accounted for by cardiovascular-related conditions or fruit and vegetable consumption but was modified after adjustment for intakes of saturated, polyunsaturated, and trans fats. There was little evidence that the -3 polyunsaturated fatty acids were associated with cognitive change. Conclusions Fish consumption may be associated with slower cognitive decline with age. Further study is needed to determine whether fat composition is the relevant dietary constituent. Obesity and Vascular Risk Factors at Midlife and the Risk of Dementia and Alzheimer Disease Miia Kivipelto; Tiia Ngandu; Fratiglioni; Matti Viitanen; Ingemar Kåreholt; Bengt Winblad; Eeva-Liisa Helkala; Jaakko Tuomilehto; Hilkka Soininen; Aulikki Nissinen Arch Neurol. 2005;62:1556-1560. ABSTRACT Background Vascular risk factors play a role in the development of dementia, including Alzheimer disease (AD). However, little is known about the effect of body mass index and clustering of vascular risk factors on the development of dementia. Objective To investigate the relation between midlife body mass index and clustering of vascular risk factors and subsequent dementia and AD. Design and Setting Participants of the Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) study were derived from random, population-based samples previously studied in a survey carried out in 1972, 1977, 1982, or 1987. After an average follow-up of 21 years, 1449 individuals (73%) aged 65 to 79 years participated in the reexamination in 1998. Main Outcome Measures Dementia and AD. Results Obesity at midlife (body mass index>30 kg/m2) was associated with the risk of dementia and AD even after adjusting for sociodemographic variables (odds ratio [OR], 2.4 [95% confidence interval (CI), 1.2-5.1]). The association was somewhat modified by further adjusting for midlife blood pressure, total cholesterol level, and smoking (OR, 2.1 [95% CI, 1.0-4.6]) and also for apolipoprotein E genotype and history of vascular disorders (OR, 1.9 [95% CI, 0.8-4.6]). Midlife obesity, high total cholesterol level, and high systolic blood pressure were all significant risk factors for dementia with ORs of around 2 for each factor, and they increased the risk additively (OR, 6.2 for the combination). Conclusions Obesity at midlife is associated with an increased risk of dementia and AD later in life. Clustering of vascular risk factors increases the risk in an additive manner. The role of weight reduction for the prevention of dementia needs to be further investigated. --- Diane Walter <dianepwalter@...> wrote: > Two studies show that eating fish once a week may delay dementia, > while obesity doubles the risk. > > http://news./s/nm/20051010/hl_nm/dementia_dc Al Pater, PhD; email: old542000@... __________________________________ Music Unlimited Access over 1 million songs. Try it free. http://music./unlimited/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 12, 2005 Report Share Posted October 12, 2005 Hi All, See the pdf-available below. 10 Oct 2005 22:27:36 -0000 Subject: [ ] Eat fish once a week Two studies show that eating fish once a week may delay dementia, while obesity doubles the risk. http://news./s/nm/20051010/hl_nm/dementia_dc EARLY RELEASE Fish Consumption and Cognitive Decline -------------------------------------------------------------------------------- and colleagues studied whether dietary intake of fish and the & #969;-3 fatty acids associated with lower risk of Alzheimer disease and stroke also are associated with slower cognitive decline. Compared with a decline rate in score of -0.100 SU/y among persons who consumed fish less than weekly, the rate was 10% slower (-0.090 SU/y) among persons who consumed 1 fish meal per week and 13% slower (-0.088 SU/y) among persons who consumed 2+ fish meals per week. FREE ARTICLE http://archneur.ama-assn.org.qe2a-proxy.mun.ca/cgi/reprint/62.12.noc50161v1 Fish Consumption and Cognitive Decline With Age in a Large Community Study Martha Clare , ScD; Denis A. , MD; C. Tangney, PhD; L. Bienias, ScD; S. , PhD Arch Neurol. 2005;62:(doi:10.1001/archneur.62.12.noc50161). ABSTRACT Background Dietary intake of fish and the -3 fatty acids have been associated with lower risk of Alzheimer disease and stroke. Objective To examine whether intakes of fish and the -3 fatty acids protect against age-related cognitive decline. Design Prospective cohort study. Setting Geographically defined Chicago, Ill, community. Participants Residents, 65 years and older, who participated in the Chicago Health and Aging Project. Main Outcome Measure Change in a global cognitive score estimated from mixed models. The global score was computed by summing scores of 4 standardized tests. In-home cognitive assessments were performed 3 times over 6 years of follow-up. Results Cognitive scores declined on average at a rate of 0.04 standardized units per year (SU/y). Fish intake was associated with a slower rate of cognitive decline in mixed models adjusted for age, sex, race, education, cognitive activity, physical activity, alcohol consumption, and total energy intake. Compared with a decline rate in score of –0.100 SU/y among persons who consumed fish less than weekly, the rate was 10% slower (–0.090 SU/y) among persons who consumed 1 fish meal per week and 13% slower (–0.088 SU/y) among persons who consumed 2 or more fish meals per week. The fish association was not accounted for by cardiovascular-related conditions or fruit and vegetable consumption but was modified after adjustment for intakes of saturated, polyunsaturated, and trans fats. There was little evidence that the -3 polyunsaturated fatty acids were associated with cognitive change. Conclusions Fish consumption may be associated with slower cognitive decline with age. Further study is needed to determine whether fat composition is the relevant dietary constituent. Obesity and Vascular Risk Factors at Midlife and the Risk of Dementia and Alzheimer Disease Miia Kivipelto; Tiia Ngandu; Fratiglioni; Matti Viitanen; Ingemar Kåreholt; Bengt Winblad; Eeva-Liisa Helkala; Jaakko Tuomilehto; Hilkka Soininen; Aulikki Nissinen Arch Neurol. 2005;62:1556-1560. ABSTRACT Background Vascular risk factors play a role in the development of dementia, including Alzheimer disease (AD). However, little is known about the effect of body mass index and clustering of vascular risk factors on the development of dementia. Objective To investigate the relation between midlife body mass index and clustering of vascular risk factors and subsequent dementia and AD. Design and Setting Participants of the Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) study were derived from random, population-based samples previously studied in a survey carried out in 1972, 1977, 1982, or 1987. After an average follow-up of 21 years, 1449 individuals (73%) aged 65 to 79 years participated in the reexamination in 1998. Main Outcome Measures Dementia and AD. Results Obesity at midlife (body mass index>30 kg/m2) was associated with the risk of dementia and AD even after adjusting for sociodemographic variables (odds ratio [OR], 2.4 [95% confidence interval (CI), 1.2-5.1]). The association was somewhat modified by further adjusting for midlife blood pressure, total cholesterol level, and smoking (OR, 2.1 [95% CI, 1.0-4.6]) and also for apolipoprotein E genotype and history of vascular disorders (OR, 1.9 [95% CI, 0.8-4.6]). Midlife obesity, high total cholesterol level, and high systolic blood pressure were all significant risk factors for dementia with ORs of around 2 for each factor, and they increased the risk additively (OR, 6.2 for the combination). Conclusions Obesity at midlife is associated with an increased risk of dementia and AD later in life. Clustering of vascular risk factors increases the risk in an additive manner. The role of weight reduction for the prevention of dementia needs to be further investigated. --- Diane Walter <dianepwalter@...> wrote: > Two studies show that eating fish once a week may delay dementia, > while obesity doubles the risk. > > http://news./s/nm/20051010/hl_nm/dementia_dc Al Pater, PhD; email: old542000@... __________________________________ Music Unlimited Access over 1 million songs. Try it free. http://music./unlimited/ Quote Link to comment Share on other sites More sharing options...
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