Re: Re: Exercise, body mass index and heart disease survival

[Guest guest]

Hi All,

When comparing the values for P in the tables 3 and 4:

> †Adjusted for age and examination year (P value for trend, <.001).

with:

> ‡Adjusted for age, examination year, fasting glucose level,

systolic blood pressure,

> parental history of premature cardiovascular disease, total

cholesterol level,

> cigarette smoking, abnormal resting, and exercise

electrocardiograms

the little difference that is seen may suggest that what you say, Rodney, may

not

apply.

--- Rodney <perspect1111@...> wrote:

> Hi folks:

>

> Two comments on this study:

>

> 1) It is BLAIR. AGAIN!!!

>

> 2) Have they really demonstrated that exercise reduces the risk of

> death from CVD in diabetics in proportion to how much they exercise?

> (Which is what they would like us to believe they have

> demonstrated). Or have they, rather, demonstrated that the more

> occluded the subjects' arteries are (and therefore the closer they

> are to infarction and death) the less capable they are of exercise

> and so, in consequence, they perform less well on the tests done by

> the investigators to determine their fitness level?

>

> IMO the latter is obviously true. Whether the former is true or not

> I really have no idea, and from what I have seen of it I do not think

> this study helps elucidate the issue. But Dr. Henry has an

> opinion, lol.

--- In , Al Pater <old542000@y...>

wrote:

> ... Table 3. Rates and Hazard Ratios of Cardiovascular Disease

Death by Body Mass

> Index and Cardiorespiratory Fitness Level

> ===============

> Cardiorespiratory fitness No. Man-years deaths Rate* HR† (95% CI)

Ptrend HR‡ (95%

> CI) Ptrend

> ===============

> BMI, 18.5-24.9 – – – <.001 – – – <.001

> Low 116 2111.7 17 79.0 4.2 (2.0-8.6) 2.7 (1.3-5.7)

> Moderate 279 5319.4 27 51.3 2.7 (1.4-5.3) 2.3 (1.2-4.6)

> High 354 6143.4 13 18.9 1.0 (Reference) 1.0 (Reference)

> BMI, 25.0-29.9 – – – <.001 – – – .07

> Low 339 5730.5 44 80.7 4.3 (2.3-7.9) 2.7 (1.4-5.1)

> Moderate 519 8068.3 31 34.9 1.9 (0.9-3.6) 1.6 (0.9-3.2)

> High 247 3408.8 12 32.5 1.7 (0.8-3.8) 1.5 (0.7-3.4)

> BMI, 30.0-34.9 – – – <.001 – – – .02

> Low 256 3622.4 27 84.2 4.5 (2.3-8.7) <.001 2.8 (1.4-5.6)

> Moderate/high 206 2305.7 8 32.2 1.7 (0.7-4.1) 1.5 (0.6-3.6)

> ===============

> Abbreviations: BMI, body mass index (calculated as weight in

kilograms divided by

> the square of height in meters); CI, confidence interval; HR,

hazard ratio from

> proportional hazard models.

> *Per 10,000 man-years with adjustment for age and examination year.

> †Adjusted for age and examination year.

> ‡Adjusted for age, examination year, fasting glucose level,

systolic blood pressure,

> parental history of premature CVD, total cholesterol level,

cigarette smoking,

> abnormal resting, and exercise electrocardiograms.

>

> ... Table 4. Rates and Hazard Ratios of Cardiovascular Disease

Death by

> Cardiorespiratory Fitness Level Quantified in 1-MET Increments

Obtained During a

> Maximal Treadmill Test

> =============

> METs No. Man-Yyars No. of deaths Rate* HR (95% CI)† HR (95% CI)‡

> =============

> <7.0 126 1602 31 142.8 2.8 (1.6-4.7) 1.6 (0.9-2.8)

> 7.0-7.9 205 3117 35 110.8 2.1 (1.3-3.5) 1.7 (1.0-2.8)

> 8.0-8.9 293 4159 35 91.7 1.8 (1.1-2.9) 1.6 (0.9-2.6)

> 9.0-9.9 415 6450 27 51.8 1.0 (Reference) 1.0 (Reference)

> 10.0-10.9 486 8078 26 41.8 0.8 (0.5-1.4) 0.9 (0.5-1.5)

> 11.0-11.9 299 5014 14 40.6 0.8 (0.4-1.5) 0.9 (0.5-1.8)

> 12.0-12.9 242 4168 5 17.1 0.3 (0.1-0.9) 0.3 (0.1-0.9)

> =/>13.0 250 4118 6 23.1 0.4 (0.2-1.1) 0.6 (0.3-1.4)

> ==============

> Abbreviations: CI, confidence interval; HR, hazard ratio from

proportional

> hazard models; METs, metabolic equivalents (1 MET = 3.5 mL of

oxygen uptake/kg -1

> per minute -1 ).

> *Per 10,000 man-years with adjustment for age and examination year.

> †Adjusted for age and examination year (P value for trend, <.001).

> ‡Adjusted for age, examination year, fasting glucose level,

systolic blood pressure,

> parental history of premature cardiovascular disease, total

cholesterol level,

> cigarette smoking, abnormal resting, and exercise

electrocardiograms (P value for

> trend, <.001).

Al Pater, PhD; email: old542000@...

__________________________________

Start your day with - Make it your home page!

http://www./r/hs

[Guest guest]

Hi All,

When comparing the values for P in the tables 3 and 4:

> †Adjusted for age and examination year (P value for trend, <.001).

with:

> ‡Adjusted for age, examination year, fasting glucose level,

systolic blood pressure,

> parental history of premature cardiovascular disease, total

cholesterol level,

> cigarette smoking, abnormal resting, and exercise

electrocardiograms

the little difference that is seen may suggest that what you say, Rodney, may

not

apply.

--- Rodney <perspect1111@...> wrote:

> Hi folks:

>

> Two comments on this study:

>

> 1) It is BLAIR. AGAIN!!!

>

> 2) Have they really demonstrated that exercise reduces the risk of

> death from CVD in diabetics in proportion to how much they exercise?

> (Which is what they would like us to believe they have

> demonstrated). Or have they, rather, demonstrated that the more

> occluded the subjects' arteries are (and therefore the closer they

> are to infarction and death) the less capable they are of exercise

> and so, in consequence, they perform less well on the tests done by

> the investigators to determine their fitness level?

>

> IMO the latter is obviously true. Whether the former is true or not

> I really have no idea, and from what I have seen of it I do not think

> this study helps elucidate the issue. But Dr. Henry has an

> opinion, lol.

--- In , Al Pater <old542000@y...>

wrote:

> ... Table 3. Rates and Hazard Ratios of Cardiovascular Disease

Death by Body Mass

> Index and Cardiorespiratory Fitness Level

> ===============

> Cardiorespiratory fitness No. Man-years deaths Rate* HR† (95% CI)

Ptrend HR‡ (95%

> CI) Ptrend

> ===============

> BMI, 18.5-24.9 – – – <.001 – – – <.001

> Low 116 2111.7 17 79.0 4.2 (2.0-8.6) 2.7 (1.3-5.7)

> Moderate 279 5319.4 27 51.3 2.7 (1.4-5.3) 2.3 (1.2-4.6)

> High 354 6143.4 13 18.9 1.0 (Reference) 1.0 (Reference)

> BMI, 25.0-29.9 – – – <.001 – – – .07

> Low 339 5730.5 44 80.7 4.3 (2.3-7.9) 2.7 (1.4-5.1)

> Moderate 519 8068.3 31 34.9 1.9 (0.9-3.6) 1.6 (0.9-3.2)

> High 247 3408.8 12 32.5 1.7 (0.8-3.8) 1.5 (0.7-3.4)

> BMI, 30.0-34.9 – – – <.001 – – – .02

> Low 256 3622.4 27 84.2 4.5 (2.3-8.7) <.001 2.8 (1.4-5.6)

> Moderate/high 206 2305.7 8 32.2 1.7 (0.7-4.1) 1.5 (0.6-3.6)

> ===============

> Abbreviations: BMI, body mass index (calculated as weight in

kilograms divided by

> the square of height in meters); CI, confidence interval; HR,

hazard ratio from

> proportional hazard models.

> *Per 10,000 man-years with adjustment for age and examination year.

> †Adjusted for age and examination year.

> ‡Adjusted for age, examination year, fasting glucose level,

systolic blood pressure,

> parental history of premature CVD, total cholesterol level,

cigarette smoking,

> abnormal resting, and exercise electrocardiograms.

>

> ... Table 4. Rates and Hazard Ratios of Cardiovascular Disease

Death by

> Cardiorespiratory Fitness Level Quantified in 1-MET Increments

Obtained During a

> Maximal Treadmill Test

> =============

> METs No. Man-Yyars No. of deaths Rate* HR (95% CI)† HR (95% CI)‡

> =============

> <7.0 126 1602 31 142.8 2.8 (1.6-4.7) 1.6 (0.9-2.8)

> 7.0-7.9 205 3117 35 110.8 2.1 (1.3-3.5) 1.7 (1.0-2.8)

> 8.0-8.9 293 4159 35 91.7 1.8 (1.1-2.9) 1.6 (0.9-2.6)

> 9.0-9.9 415 6450 27 51.8 1.0 (Reference) 1.0 (Reference)

> 10.0-10.9 486 8078 26 41.8 0.8 (0.5-1.4) 0.9 (0.5-1.5)

> 11.0-11.9 299 5014 14 40.6 0.8 (0.4-1.5) 0.9 (0.5-1.8)

> 12.0-12.9 242 4168 5 17.1 0.3 (0.1-0.9) 0.3 (0.1-0.9)

> =/>13.0 250 4118 6 23.1 0.4 (0.2-1.1) 0.6 (0.3-1.4)

> ==============

> Abbreviations: CI, confidence interval; HR, hazard ratio from

proportional

> hazard models; METs, metabolic equivalents (1 MET = 3.5 mL of

oxygen uptake/kg -1

> per minute -1 ).

> *Per 10,000 man-years with adjustment for age and examination year.

> †Adjusted for age and examination year (P value for trend, <.001).

> ‡Adjusted for age, examination year, fasting glucose level,

systolic blood pressure,

> parental history of premature cardiovascular disease, total

cholesterol level,

> cigarette smoking, abnormal resting, and exercise

electrocardiograms (P value for

> trend, <.001).

Al Pater, PhD; email: old542000@...

__________________________________

Start your day with - Make it your home page!

http://www./r/hs