Re: Vioxx RX

[Guest guest]

Hello Jo hon *hug*

"She ordered 25mg a day - is that a logical dosage? What are others taking for the chronic daily migraine?"

I dont even know what it is!! LOL ... I know I have not been on it. I am on preventatives (amitriptyline 100mg and metopropol 100mg) but when I get the hormone migraine from hell nothing seems to stop it. So let me know how you go on this one! If it helps I'll ask my neuro. I'm collecting names of migraine meds. 25mg sounds like a low dose to me, but then again I know nothing of it. Perhaps its the starting dose and you build up to a higher dose? When in doubt ask your dr hon.

"Although the Tolectin did nothing for my migraines I was pleasantly surprised (thrilled is the word) that it actually helped tremendously with my frozen shoulder - I have more range of motion than I have had in months. So let's hope the Vioxx keeps that going in the right direction."

Absolutely! Its like me and my migraine preventatives. They dont stop the migraines but help with the neuralgia and myoclonus! Whatever works is a blessing!

Good luck with it!! How is your sons hand?

Love Aisha.

[Guest guest]

In a message dated 8/19/00 1:09:58 AM Central Daylight Time,

aisha@... writes:

<< So let me know how you go on this one! If it helps I'll ask my neuro. I'm

collecting names of migraine meds. 25mg sounds like a low dose to me, but

then again I know nothing of it. Perhaps its the starting dose and you build

up to a higher dose? When in doubt ask your dr hon. >>

Aisha

She said that 25 is a stronger dosage but because of the constant migraine

she thought that it was warranted. I am just trying to get a handle on what

works for other migraine folks who take that. Actually I had a brain death

moment and sent to to the BS list as well as the migraine list.

Lord could I give you a list of migraine meds - I have been on 32 different

ones - well make that 34 now. I am not sure I can even remember all of them.

Can't take the triptans so have to do something.

Vioxx is brand name for Refobicob or some thing like that. LOL I am drugged

on codeine and compazine at the moment so my mind is not clear.

Hugs,

Jo

[Guest guest]

In a message dated 8/19/00 8:46:18 AM Central Daylight Time,

tulips3@... writes:

<<

The HMO requirements do sound pretty troublesome. have you tried other class

of meds? Have u tried Naramig? I have tried so many meds too.... almost every

class possible, for my headaches. Presently, Vioxx works the best for me. I

am supposed to take 25mg a day when necessary, although I can increase it to

50mg a day myself when the pain is really bad. My mum is also prescribed 25mg

for her leg pain. So, I guess this is a logical dose?

Vioxx does not work fantastically for me. If the pain gets intolerable, I

will normallly fix an appointment to see my doc. I hate pills actually,

especially after taking so many types which did not work. So if Vioxx does

not work, I just groan and shut myself down. >>

Ling,

I have never heard of Naramig. What type of med is it?

Neither my doctor or I expect that the Vioxx will stop the migraines. But I

have Chronic Daily Headache in addition to the migraines that happen 4-5 days

a week. So we are hoping to at least stop the CDH so that I can deal better

with the non-migraine days.

I take Compazine and Tylenol with Codeine for the migraines.

These things are truly exhausting. Right now I am so drugged I am working

with one eye shut.

Jo

[Guest guest]

Anne

Thanks for the drug info. I had already found and printed all of it, but I

hope others can benefit. My cousin is a doctor so she also gave me the info.

She even gave me a bunch of free samples so I could take what my doctor

prescribed while I waited for the authorization to go through.

I just goofed in my mailing and sent the post to this list as well as to my

migraine list. I was trying to get a handle on what dosage works for others

for the migraine/CDH thing since my doctor was not sure what would be most

beneficial. The literature does not really address the use for migraines.

Thanks for sharing what you found.

I hope I will be able to continue taking it.

Hugs,

Jo

[Guest guest]

Ling,

I have never heard of Naramig. What type of med is it?

Naramig

is the brand name Glaxo uses in Europe for Naratriptan (Amerge on the other

side of the pond). It has has a long time action (6 to 8 hours). I take

it before going to bed, and sometimes it helps me to suppress the

nighttime

attacks.

http://www.mapinc.org/drugnews/v98/n101/a07.html

Pubdate:

Wed, 11 Feb 1998

FDA

CLEARS NEW DRUG FOR MIGRAINE

WASHINGTON - Pharmaceutical giant Glaxo-Wellcome said Wednesday

it had won marketing clearance from the Food and Drug

Administration (FDA) for Amerge, a new, longer-acting migraine

medicine.

Amerge, known generically as naratriptan, is one of a newer class of

migraine drugs called triptans that act on a brain chemical known as

serotonin.

Scientists are not sure just how they work, but they can reduce the

pain of migraines and symptoms such as the auras that many

sufferers see around objects.

In clinical trials, between 60 and 66 percent of volunteers with

moderate to severe headache said Amerge helped their pain within

four hours, and the pain stayed away for a day in between 72 and 81

percent of the volunteers.

More than 26 million people in the U.S. suffer from migraine.

It

affects 585 million people worldwide or one in 10 of the world's

population.

Besides causing severe headache, migraines can also cause nausea,

vomiting, and sensitivity to light, sound and smell. Attacks can

last

from four to 72 hours.

Amerge is meant to have longer-lasting effects than Imitrex

(sumatriptan), Glaxo's other triptan.

``While Imitrex offers fast relief and efficacy, there are many

migraine sufferers for whom the long duration of their headaches is

of greatest concern,'' Dr Ninan Mathew of the Houston Headache

Clinic in Texas, who helped in trials of the drug, said in a statement.

"The introduction of Amerge provides another option for these

sufferers to be treated for this debilitating disease. This medication

is effective, long-lasting and well-tolerated in most patients."

People who have symptoms or signs of ischemic heart disease,

including chest pain or heart attack, stroke, high blood pressure or

other vascular problems, should not take Amerge or any other triptan

because it can constrict the arteries leading from the heart.

It also should not be taken with other migraine medications.

Many companies are racing to get new migraine drugs onto the

market.

In December the FDA approved a new nose-spray formulation of

Novartis Pharmaceuticals' Migranal, just after Glaxo won approval for

a nose-spray formulation of Imitrex.

There are also over-the-counter remedies. Last month the FDA said

Bristol-Myers Squibb could package its Excedrin Extra Strength as a

migraine medicine.

Analysts have estimated that Imitrex, sold as Imigran in Europe,

holds as much as 70 percent of the $1.1 billion global migraine

market. Naratriptan is already sold as Naramig in Europe.

Title:

DG DISPATCH - HEADACHE: Naratriptan Useful For Non-Severe Migraines

http://www.docguide.com/dg.nsf/PrintPrint/6B0D7D019DDE969E8525679F0048A98F

I take Compazine and Tylenol with Codeine for the

migraines.

Both of

the meds above... the compazine & the codeine I am allergic to!

I know

that compazine is a medication used often with migraines, but one dose

of this drug, and I was in BIG trouble!!!

The only

drug I can have for N/V is Vistaril (Hydroxyzine HCl)

I hope

this information about the Naramig / Amerge is helpful. I also sent

another description separately for this drug also!

These things are truly exhausting. Right now

I am so drugged I am working

with one eye shut.

Jo

I hope you

are able to get some sleep, so that the pain will get better!

Sweet

Dreams!

Anne

[Guest guest]

Hi Jo,

<<I have never heard of Naramig. What type of med is it?>>

Sorry for my slow reply, I only check my mails once a day. It is a special tablet mainly for migraine, produced by GlaxoWellcome. Another name for it is naratriptan.It is expensive, though. Another tablet that helped me a little apart from Vioxx is actually Tramadol.

Ling

[Guest guest]

In a message dated 8/20/00 5:39:57 PM Central Daylight Time,

unique@... writes:

<< I have been told by my doc that its a big no no when things going in to

the liver.

Anything that goes throught the liver and you have liver problems its a

Big No No

>>

This is true for any medication that is metabolized in the liver. If you

have problems with your liver, from a wide variety of ailments, then you must

be careful what medications you take, INCLUDING over the counter drugs.

I don't have any problems with my liver at this point. I had a severe

hepatitis as the result of mononucleosis when I was 30, but that finally

resolved itself and I think mow my liver is the only organ in my body that

seems to still be functioning normally so I can take the meds I need.

Jo

[Guest guest]

I have been told by my doc that its a big no no when things going in to the liver.

Anything that goes throught the liver and you have liver problems its a

Big No No

M