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Vaccines and Diabetes

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FYI.

Lyndon McGill, DC

Salem, Oregon

Childhood Vaccinations Are Not Associated With Risk of Type 1

Diabetes:

NEW YORK (Reuters Health) Dec 17 - There is no association between

routinely recommended childhood vaccines and an increased risk of type 1

diabetes, according to a report in the online December edition of

Pediatrics.

In a population-based, case-control study, Dr. DeStefano, of the

US Centers for Disease Control and Prevention, Atlanta, and colleagues

examined associations between childhood vaccinations, especially

against hepatitis B and Haemophilus influenza type b (Hib), and the risk

of developing diabetes. They also examined whether timing of vaccination

influenced risk.

Two hundred fifty-two subjects with confirmed diabetes and 768 matched

controls were included in the study. " The odds ratio for the association

with type 1 diabetes was 0.28 for whole cell pertussis vaccine...1.36

for measles-mumps-rubella, 1.14 for Hib, 0.81 for hepatitis B vaccine,

1.16 for varicella vaccine, and 0.92 for acellular pertussis-containing

vaccines, " the team notes.

Children who had received hepatitis B vaccine at birth had an odds ratio

for diabetes of 0.51 compared with those who had not been vaccinated.

Children first vaccinated at 2 months of age or later had an odds ratio

of

0.86 compared with those not vaccinated.

The investigators observed an independent association between race and

ethnicity and family history of diabetes and type 1 diabetes risk.

However, " adjustment for these factors did not materially alter the odds

ratios for any of the vaccines, " Dr. DeStefano and colleagues conclude.

Pediatrics 2001;108:00-00.

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