Guest guest Posted July 19, 2003 Report Share Posted July 19, 2003 In a message dated 7/19/03 8:52:12 PM Eastern Daylight Time, jafasum@... writes: > Ketogenic diets work very well for a large portion of epileptics, also. > Most are able to get off of their medications. There is quite a bit written up > on this on the web. And if you search medline too. When I did a search for " ketogenic diet " almost everything that came up was on epilepsy, so I narrowed it down by adding " cancer " into it. Chris Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 19, 2003 Report Share Posted July 19, 2003 In a message dated 7/19/03 10:17:53 PM Eastern Daylight Time, s.fisher22@... writes: > ---->why? is there some connection between carb consumption, or *grain* > consumption and epilepsy? It appears no one really knows. It has to do with detailed brain chemistry. It has different effectiveness with different people and different types of epilepsy, but a large majority improve and one study found around 30% had >90% improvement. In some people it appears it might have to do with a defect in transporting glucose to the brain, so ketones can replace the defectively transported glucose. There are more details that even the neuroscientists don't pretend to understand having to do with chemical imbalances int he brain and the way metabolic byproducts and whatnot effect them. Ketogenic diets are considered comparable to anti-eplieptic drugs, and one study found that while calorie restriction in itself could be anti-convulsant, ketogenic calorie-restricted diet was more effective and not only anti-convulsant, but " anti-epileptogenic. " I'm not sure what that means unless it means ketogenic diets can *prevent* epilepsy. Not sure how they tested that? Maybe administered to people identified as genetically predisposed before they developed it? Dunno, anyway, if you could get your hands on the full-text of the below article, it woudl probably best answer your question. Chris Nutr Neurosci. 2003 Apr;6(2):67-79. <A HREF= " http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed & cmd=Display & dopt=p\ ubmed_pubmed & from_uid=12722982 " >Related Articles,</A> >Links</A> The ketogenic diet for the treatment of epilepsy: a challenge for nutritional neuroscientists. Stafstrom CE, Bough KJ. Department of Neurology and the Neuroscience Training Program, University of Wisconsin, Madison, WI 53792, USA. The ketogenic diet (KD) is a high-fat, low-carbohydrate, adequate-protein diet that has been used for more than eight decades for the treatment of refractory epilepsy in children. Despite this long history, the mechanisms by which the KD exerts its anti-seizure action are not fully understood. Questions remain regarding several aspects of KD action, including its effects on brain biochemistry and energetics, neuronal membrane function and cellular network behavior. With the explosion of the KD use in the last 10 years, it is now imperative that we understand these factors in greater detail, in order to optimize the formulation, administration and fine-tuning of the diet. This review discusses what is known and what remains to be learned about the KD, with emphasis on clinical questions that can be approached in the laboratory. We encourage scientists with a primary interest in nutritional neuroscience to join with those of us in the epilepsy research community to address these urgent questions, for the benefit of children ravaged by intractable seizures. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 Ketogenic diets work very well for a large portion of epileptics, also. Most are able to get off of their medications. There is quite a bit written up on this on the web. Jafa ChrisMasterjohn@... wrote: Also worth looking into the following: " There have allso been reports in the peer-reviewed literature of cancer patients in the grips of apparently hopelessly fatal cancers who have experienced dramatic improvements and recoveries on a ketogenic diet. This diet provides energy through fats, not carbohydrates. Although this is a much stricter, more difficult diet to follow, it starves the cancer cells of the glucose they need to reproduce. It is the relentless reproduction of cancer cells and their displacement of healthy ones that is cancer's greatest threat. By slowing or halting this reproduction, the ketogenic diet allows the immune system a window of opportunity to battle these aberrant cells. " --Dangerous Grains, p 108, Brady MD and Hoggan, MA In a message dated 7/18/03 11:40:46 PM Eastern Daylight Time, toyotaokiec@... writes: > > >OK. I know the vegan recommendation for the above is a raw vegan > diet. But > >what do NT'ers suggest. I have read the article on WAP already. > Anything else? > >My aunt was just diagnosed with invasive breast cancer today. > > > >Marcella > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 > Ketogenic diets work very well for a large portion of epileptics, also. > Most are able to get off of their medications. There is quite a bit written up > on this on the web. >>And if you search medline too. When I did a search for " ketogenic diet " almost everything that came up was on epilepsy, so I narrowed it down by adding " cancer " into it. ---->why? is there some connection between carb consumption, or *grain* consumption and epilepsy? Suze Fisher Lapdog Design, Inc. Web Design & Development http://members.bellatlantic.net/~vze3shjg/ mailto:s.fisher22@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 >---->why? is there some connection between carb consumption, or *grain* >consumption and epilepsy? > >Suze Fisher It's an open question. So far it has been assumed it is carb consumption, but no one really knows why it works. Celiac is decidedly associated with seizures though, so it could be just that there are two different modes of inquiry. No one in this country tests epileptic kids for gluten intolerance. They seem to do that testing in Europe though: one member of the celiac group passed out on the stairs to a cathedral and was immediately blood-tested for celiac -- that's how she found out she had it! -- Heidi Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 >>> In some people it appears it might have to do with a defect in transporting glucose to the brain, so ketones can replace the defectively transported glucose. ------->hmmm...i was under the impression that the brain can use ONLY glucose as fuel. which, if true, in a ketogenic diet, would have to come from gluconeogenic amino acids, i'd imagine. Suze Fisher Lapdog Design, Inc. Web Design & Development http://members.bellatlantic.net/~vze3shjg/ mailto:s.fisher22@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 In a message dated 7/20/03 3:24:15 AM Eastern Daylight Time, heidis@... writes: > It's an open question. So far it has been assumed it is carb consumption, > but no one really knows why it works. Celiac is decidedly associated > with seizures though, so it could be just that there are two different > modes of inquiry. No one in this country tests epileptic kids for > gluten intolerance. They seem to do that testing in Europe though: > one member of the celiac group passed out on the stairs to a cathedral > and was immediately blood-tested for celiac -- that's how she found out > she had it! > Oh there's probably definitely something intestinal going on, and since the neuroscientists admit they have simply no clue at all, it's all the more likely. " There have been many babies with chronic diarrhea accompanied by epileptic seizures. One baby was on commercial formula and was eating some solid foods. When his diet was changed to the Specific Carbohydrate Diet, both diarrhea and the epileptic seizures cleared up. He continues to do well siz years later. Another baby with seizures was being breastfed and was also eating cereal. The mother went on the SCD, the baby was allowed only those foods on the diet, and the epilepsy disappeared. He has been free of seizures for five years. " --Gotschall, BVC, p41 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 In a message dated 7/20/03 8:58:17 AM Eastern Daylight Time, s.fisher22@... writes: > ------->hmmm...i was under the impression that the brain can use ONLY > glucose as fuel. which, if true, in a ketogenic diet, would have to come > from gluconeogenic amino acids, i'd imagine. I was under that impression too, but it's clearly wrong. There's no such thing as a ketogenic diet where glucose is the fuel-- that would be a glucogenic diet. Chris Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 Suze, >>---->why? is there some connection between carb consumption, or *grain* >>consumption and epilepsy? Dangerous Grains pg. 153 Epilepsy Published reports of food allergy induced seizures go all the way back to 1914. Although there were a few reports of the causative relationship between celiac disease and epilepsy prior to the late 1980's, the connection has received increasing attention over the last 15 years or so. Celiac associated epilepsy has been reported to occur in connection with migraine headaches, hyperactivity, calcium deposits in the brain and in cases of blood vessel abnormalities in the brain. Celiac disease is now well recognized as a factor in most cases of epilepsy where calcium deposits are found in certain regions of the brain. Theorizing from other bits malabsorption, leaky gut, magnesium deficiency (induced by gluten sensitivity, proven effective in reducing epileptic seizures) and phytates would be involved. The 11% reduction in human brain size (think thats from Biochemical Individuality) since the introduction of agriculture. Ketogenic diet study makes total sense here to me in that it eliminates gluten and gives the good fats that will feed the brain just like the hunter- gatherer diet. Wanita Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 Wanita, That's a very good point. Any grain or starch will contribute to magnesium deficiency regardless of gluten, because excessive insulin causes magnesium deficiency. See Ron Rosedale's lecture on insulin on Mercola's site for more info. If you do a search for " ron rosedale insulin " you'll find it. I believe it's called " Insulin and its metabolic effects. " So I think the results of the ketogenic diet are broader than gluten in that they basically eliminate starch from the diet, and and any carbs in the diet are, vis-a-vis insulin anyway, buffered by the large amount of fat. Chris In a message dated 7/20/03 10:31:58 AM Eastern Daylight Time, wanitawa@... writes: > Theorizing from other bits malabsorption, leaky gut, magnesium deficiency > (induced by gluten sensitivity, proven effective in reducing epileptic > seizures) and phytates would be involved. The 11% reduction in human brain > size > (think thats from Biochemical Individuality) since the introduction of > agriculture. Ketogenic diet study makes total sense here to me in that it > eliminates gluten and gives the good fats that will feed the brain just like > the hunter- gatherer diet. " To announce that there must be no criticism of the president, or that we are to stand by the president, right or wrong, is not only unpatriotic and servile, but is morally treasonable to the American public. " --Theodore Roosevelt Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 In a message dated 7/20/03 2:01:45 PM Eastern Daylight Time, jafasum@... writes: > I wasn't aware that the ketogenic diet is given mainly to children. And > that children have the best results with this type of diet. If this is the > case, it would seem that the digestive issues (ie celiac, etc.) do have a lot > of merit. But what about adult onset epilepsy? Why is the ketogenic diet not > as effective? If the person didn't have some sort of brain damage, the > cause appears to be something else in an adult. Jafa, I'm not aware of that either. I didn't read anything in the abstracts I've read that indicates that, though I did read several that specifically dealt with childhood epilepsy. The post you responded too was regarding the SCD, which is not ketogenic, but is designed to eliminate fermantable carbohydrates temporarily to allow the intestine to heal. Chris Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 In a message dated 7/20/03 2:36:57 PM Eastern Daylight Time, s.fisher22@... writes: > ------->so, it's been determined that the amino acids that serve as glucose > precursors are definitely not the fuel source for the brain on a ketogenic > diet? One of the main things they measure in the ketogenic diets are decreases in glucose levels and increases in ketone levels. Chris Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 Suze- IIRC Atkins says that the brain actually prefers ketones to glucose. >i was under the impression that the brain can use ONLY >glucose as fuel. which, if true, in a ketogenic diet, would have to come >from gluconeogenic amino acids, i'd imagine. - Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 I wasn't aware that the ketogenic diet is given mainly to children. And that children have the best results with this type of diet. If this is the case, it would seem that the digestive issues (ie celiac, etc.) do have a lot of merit. But what about adult onset epilepsy? Why is the ketogenic diet not as effective? If the person didn't have some sort of brain damage, the cause appears to be something else in an adult. Jafa ChrisMasterjohn@... wrote: In a message dated 7/20/03 3:24:15 AM Eastern Daylight Time, heidis@... writes: > It's an open question. So far it has been assumed it is carb consumption, > but no one really knows why it works. Celiac is decidedly associated > with seizures though, so it could be just that there are two different > modes of inquiry. No one in this country tests epileptic kids for > gluten intolerance. They seem to do that testing in Europe though: > one member of the celiac group passed out on the stairs to a cathedral > and was immediately blood-tested for celiac -- that's how she found out > she had it! > Oh there's probably definitely something intestinal going on, and since the neuroscientists admit they have simply no clue at all, it's all the more likely. " There have been many babies with chronic diarrhea accompanied by epileptic seizures. One baby was on commercial formula and was eating some solid foods. When his diet was changed to the Specific Carbohydrate Diet, both diarrhea and the epileptic seizures cleared up. He continues to do well siz years later. Another baby with seizures was being breastfed and was also eating cereal. The mother went on the SCD, the baby was allowed only those foods on the diet, and the epilepsy disappeared. He has been free of seizures for five years. " --Gotschall, BVC, p41 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 > ------->hmmm...i was under the impression that the brain can use ONLY > glucose as fuel. which, if true, in a ketogenic diet, would have to come > from gluconeogenic amino acids, i'd imagine. >>>>I was under that impression too, but it's clearly wrong. There's no such thing as a ketogenic diet where glucose is the fuel-- that would be a glucogenic diet. ------->so, it's been determined that the amino acids that serve as glucose precursors are definitely not the fuel source for the brain on a ketogenic diet? Suze Fisher Lapdog Design, Inc. Web Design & Development http://members.bellatlantic.net/~vze3shjg/ mailto:s.fisher22@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 Jafa, >I wasn't aware that the ketogenic diet is given mainly to children. And that children have the best results with this type of diet. If this is the case, it would seem that the digestive issues (ie celiac, etc.) do have a lot of merit. But what about adult onset epilepsy? Why is the ketogenic diet not as effective?  If the person didn't have some sort of brain damage, the cause appears to be something else in an adult. This may help. Just read in the Schwarzbein Principle pg. 13. When insulin levels are kept high too long, the result is a physiology that promotes excessive body-fat gain, a physiology prone to infections and all the chronic degenerative diseases of aging: osteoarthritis, different types of cancer, cholesterol abnormalities, coronary artery disease, less lean body mass with excess body fat, high blood pressure, osteoporosis, stroke and Type II diabetes. The medical establishment considers these degenerative diseases to be genetically transmitted. Again, I disagree. Consider the following: Genetic diseases manifest themselves and are diagnosed in childhood or early adolescence. Excessive body-fat gain and decreased lean body mass, as well as the diseases listed above, occur primarily in adults and are usually manifested after age thirty. By the time you are thirty years old, your cells do not utilize sugar as well as they did when younger; this is cellular aging. But time is not the only factor that causes cellular aging. What you have eaten and how you have lived your life will determine the actual age of your cells, and therefore the health of your metabolism at any given time. In other words, even though thirty year olds are the same chronological age, they are different metabolic ages. Wanita Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2003 Report Share Posted July 20, 2003 >I wasn't aware that the ketogenic diet is given mainly to children. And that children have the best results with this type of diet. If this is the case, it would seem that the digestive issues (ie celiac, etc.) do have a lot of merit. But what about adult onset epilepsy? Why is the ketogenic diet not as effective? If the person didn't have some sort of brain damage, the cause appears to be something else in an adult. > >Jafa I'm not sure that it *isn't* used on adults. My guess is that one reason the kids get it is that the adults force them to, and parents tend to do a lot of research for their kids. It is really, really hard to stick to a ketogenic diet -- people crave carbs! Some adults DO get lesions and calcium deposits and all those other things that have been mentioned, from gluten -- and there could well be problems from other starch issues -- but in *either* case the docs will mainly put the person on drugs, not try dietary interventions. Quote Link to comment Share on other sites More sharing options...
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