resistant denture stomatitis

[Guest guest]

thank you so much for a great answer:)

>

> the answer for angular cheilitis associated with denture stomatitis but

resistant to Nystatin is Miconazole gel. the reason is angular cheilitis can be

caused either by candida which is a commensal of the oral cavity or by

Staphylococcus aureus which resides in the nasal cavity(at the entrance). So a

possible cause for angular cheilitis could be this S. aureus which responds well

to fusidic acid powders and miconazole gel. Miconazole gel can act against both

candida and S.aureus. hope this helps

>

[Guest guest]

according to BNF;

for angular cheilitis:

While the underlying cause is being identified and treated, it is often helpful to apply miconazole cream or sodium fusidate ointment ; if the angular cheilitis is unresponsive to treatment, miconazole and hydrocortisone cream or ointment can be used.

in terms of denture stomatitis:

Drugs used in oropharyngeal candidiasis

Nystatin is not absorbed from the gastro-intestinal tract and is applied locally (as a suspension) to the mouth for treating local fungal infections. Miconazole is applied locally (as an oral gel) in the mouth but it is absorbed to the extent that potential interactions need to be considered. Miconazole also has some activity against Gram-positive bacteria including streptococci and staphylococci. Fluconazole (section 5.2.1) is given by mouth for infections that do not respond to topical therapy or when topical therapy cannot be used. It is reliably absorbed and effective. Itraconazole (section 5.2.1) can be used for fluconazole-resistant infections

hope that helps

From: Enigma <wiseguy944@...> Sent: Tuesday, 27 December 2011, 12:12Subject: resistant denture stomatitis

thank you so much for a great answer:)>> the answer for angular cheilitis associated with denture stomatitis but resistant to Nystatin is Miconazole gel. the reason is angular cheilitis can be caused either by candida which is a commensal of the oral cavity or by Staphylococcus aureus which resides in the nasal cavity(at the entrance). So a possible cause for angular cheilitis could be this S. aureus which responds well to fusidic acid powders and miconazole gel. Miconazole gel can act against both candida and S.aureus. hope this helps>