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Here in Africa ( Angola) Just changed from Streptokinse to TPA.

Brash

Senior Nurse Supervisor

Cabinda Gulf Oil Company

e-mail: Amed2@...

Telephone: CTN. 8 345 2696

Via London 020 74878100 Cabinda Ext. 2696

> Thrombolysing

>

> Any one on the list thrombolysing in the field?

>

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Excellent,

what are you using as diagnostic conformation?

Pain

ECG

Biochemistry

Any two will do. If you are just using pain and ECG what do you do about

false negatives? How do you confirm apositive ECG? Telemedicene? Have you

had to use it much? What is your pain to needle time average?

>From: " Brash, \\ Lines, Gavin (amed2) " <amed2@...>

>Reply-

> " ' ' "

>< >

>Subject: RE: Thrombolysing

>Date: Thu, 31 Jan 2002 09:31:10 -0800

>

>Here in Africa ( Angola) Just changed from Streptokinse to TPA.

>

>

>

> Brash

>Senior Nurse Supervisor

>Cabinda Gulf Oil Company

>e-mail: Amed2@...

>Telephone: CTN. 8 345 2696

>Via London 020 74878100 Cabinda Ext. 2696

>

> > Thrombolysing

> >

> > Any one on the list thrombolysing in the field?

> >

> > _________________________________________________________________

> > Join the world's largest e-mail service with MSN Hotmail.

> > http://www.hotmail.com

> >

> >

> >

> >

> > Member Information:

> >

> > List owner: Ian Sharpe Owner@...

> > Editor: Ross Boardman Editor@...

> >

> > Post message: egroups

> > Subscribe: -subscribeegroups

> > Unsubscribe: -unsubscribeegroups

> >

> > Thank you for supporting Remote Medics Online.

> >

> >

> >

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> >

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History,

Symptoms

St elevation in 2 leads

Biochemical Marker Tropinin

Confirmation is Tropinin test however History Typical Symptoms and ECG

changes are enough we don't usually wait for the biochemistry.

Less than 60 minutes onset to needle.

No used very often

Brash \ Gavin Lines

Senior Nurse Supervisor

Cabinda Gulf Oil Company

e-mail: Amed2@...

Telephone: CTN. 8 345 2696

Via London 020 74878100 Cabinda Ext. 2696

> Thrombolysing

> > >

> > > Any one on the list thrombolysing in the field?

> > >

> > > _________________________________________________________________

> > > Join the world's largest e-mail service with MSN Hotmail.

> > > http://www.hotmail.com

> > >

> > >

> > >

> > >

> > > Member Information:

> > >

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> > > Editor: Ross Boardman Editor@...

> > >

> > > Post message: egroups

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> > > Unsubscribe: -unsubscribeegroups

> > >

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Tropinin is a test which only requires a drop of blood or serum and comes

back pos or Neg about 30 Minutes....

Brash \ Gavin Lines

Senior Nurse Supervisor

Cabinda Gulf Oil Company

e-mail: Amed2@...

Telephone: CTN. 8 345 2696

Via London 020 74878100 Cabinda Ext. 2696

> Thrombolysing

> > > >

> > > > Any one on the list thrombolysing in the field?

> > > >

> > > > _________________________________________________________________

> > > > Join the world's largest e-mail service with MSN Hotmail.

> > > > http://www.hotmail.com

> > > >

> > > >

> > > >

> > > >

> > > > Member Information:

> > > >

> > > > List owner: Ian Sharpe Owner@...

> > > > Editor: Ross Boardman Editor@...

> > > >

> > > > Post message: egroups

> > > > Subscribe: -subscribeegroups

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Don't usually wait for bio chem, but send it off and will view it if ECG is

negative in case of a false negative? Who authorises? Doctor in country,

at home or yourself?

>From: " Brash, \\ Lines, Gavin (amed2) " <amed2@...>

>Reply-

> " ' ' "

>< >

>Subject: RE: Thrombolysing

>Date: Fri, 1 Feb 2002 06:06:44 -0600

>

>History,

>Symptoms

>St elevation in 2 leads

>Biochemical Marker Tropinin

>

>Confirmation is Tropinin test however History Typical Symptoms and ECG

>changes are enough we don't usually wait for the biochemistry.

>

>Less than 60 minutes onset to needle.

>

>No used very often

>

> Brash \ Gavin Lines

>Senior Nurse Supervisor

>Cabinda Gulf Oil Company

>e-mail: Amed2@...

>Telephone: CTN. 8 345 2696

>Via London 020 74878100 Cabinda Ext. 2696

>

> > Thrombolysing

> > > >

> > > > Any one on the list thrombolysing in the field?

> > > >

> > > > _________________________________________________________________

> > > > Join the world's largest e-mail service with MSN Hotmail.

> > > > http://www.hotmail.com

> > > >

> > > >

> > > >

> > > >

> > > > Member Information:

> > > >

> > > > List owner: Ian Sharpe Owner@...

> > > > Editor: Ross Boardman Editor@...

> > > >

> > > > Post message: egroups

> > > > Subscribe: -subscribeegroups

> > > > Unsubscribe: -unsubscribeegroups

> > > >

> > > > Thank you for supporting Remote Medics Online.

> > > >

> > > >

> > > >

> > > >

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Mike, (or Garry)

There is now available a Tropinin test that is much like a pregnancy test,

giving an almost instantaneous result, simple spot of blood on the marker I

think two lines indicate a pos and one line a neg. Only trouble is you need

to have venous access as the measured drop of blood has to be a bit more

specific.

First saw them a couple of weekends ago when out with Staffs Amb who are at

present trialing the idea. I can find out more details if you are

interested.....

Can't for the life of me remember what the test was called or who the

manufacturer was....

B. Rgs

Ian

Thrombolysing

> > >

> > > Any one on the list thrombolysing in the field?

> > >

> > > _________________________________________________________________

> > > Join the world's largest e-mail service with MSN Hotmail.

> > > http://www.hotmail.com

> > >

> > >

> > >

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> > >

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> > > Editor: Ross Boardman Editor@...

> > >

> > > Post message: egroups

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> > > Unsubscribe: -unsubscribeegroups

> > >

> > > Thank you for supporting Remote Medics Online.

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It's called Trop T made by Roche expensive comes in Boxes of 5

Brash \ Gavin Lines

Senior Nurse Supervisor

Cabinda Gulf Oil Company

e-mail: Amed2@...

Telephone: CTN. 8 345 2696

Via London 020 74878100 Cabinda Ext. 2696

> Thrombolysing

> > > >

> > > > Any one on the list thrombolysing in the field?

> > > >

> > > > _________________________________________________________________

> > > > Join the world's largest e-mail service with MSN Hotmail.

> > > > http://www.hotmail.com

> > > >

> > > >

> > > >

> > > >

> > > > Member Information:

> > > >

> > > > List owner: Ian Sharpe Owner@...

> > > > Editor: Ross Boardman Editor@...

> > > >

> > > > Post message: egroups

> > > > Subscribe: -subscribeegroups

> > > > Unsubscribe: -unsubscribeegroups

> > > >

> > > > Thank you for supporting Remote Medics Online.

> > > >

> > > >

> > > >

> > > >

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doc in country Authorises

Brash \ Gavin Lines

Senior Nurse Supervisor

Cabinda Gulf Oil Company

e-mail: Amed2@...

Telephone: CTN. 8 345 2696

Via London 020 74878100 Cabinda Ext. 2696

> Thrombolysing

> > > > >

> > > > > Any one on the list thrombolysing in the field?

> > > > >

> > > > > _________________________________________________________________

> > > > > Join the world's largest e-mail service with MSN Hotmail.

> > > > > http://www.hotmail.com

> > > > >

> > > > >

> > > > >

> > > > >

> > > > > Member Information:

> > > > >

> > > > > List owner: Ian Sharpe Owner@...

> > > > > Editor: Ross Boardman Editor@...

> > > > >

> > > > > Post message: egroups

> > > > > Subscribe: -subscribeegroups

> > > > > Unsubscribe: -unsubscribeegroups

> > > > >

> > > > > Thank you for supporting Remote Medics Online.

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >

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Would be interested

>From: <Owner@...>

>Reply-

>< >

>Subject: RE: Thrombolysing

>Date: Fri, 1 Feb 2002 14:38:46 -0000

>

>Mike, (or Garry)

>

>There is now available a Tropinin test that is much like a pregnancy test,

>giving an almost instantaneous result, simple spot of blood on the marker I

>think two lines indicate a pos and one line a neg. Only trouble is you need

>to have venous access as the measured drop of blood has to be a bit more

>specific.

>

>First saw them a couple of weekends ago when out with Staffs Amb who are at

>present trialing the idea. I can find out more details if you are

>interested.....

>

>Can't for the life of me remember what the test was called or who the

>manufacturer was....

>

>B. Rgs

>

>Ian

>

> Thrombolysing

> > > >

> > > > Any one on the list thrombolysing in the field?

> > > >

> > > > _________________________________________________________________

> > > > Join the world's largest e-mail service with MSN Hotmail.

> > > > http://www.hotmail.com

> > > >

> > > >

> > > >

> > > >

> > > > Member Information:

> > > >

> > > > List owner: Ian Sharpe Owner@...

> > > > Editor: Ross Boardman Editor@...

> > > >

> > > > Post message: egroups

> > > > Subscribe: -subscribeegroups

> > > > Unsubscribe: -unsubscribeegroups

> > > >

> > > > Thank you for supporting Remote Medics Online.

> > > >

> > > >

> > > >

> > > >

> > > >

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Sorry to be a pain and pick your brains like this. How robust is the bed

side test? Temp, humidity, travel, sensitivity, shelf life? There will be

data available from Roche but the comparison may well have been done against

traditional bio chem markers in hospital and not after it has traveled to

Angola and been with customs for a while.

Have you done any comparisons on your patients? Does Roche lay down strict

guidelines that they will not garantee the test if the conditions have not

been maintained?

travel, shelf life, sensitivity? There must be data on

>From: " Brash, \\ Lines, Gavin (amed2) " <amed2@...>

>Reply-

> " ' ' "

>< >

>Subject: RE: Thrombolysing

>Date: Fri, 1 Feb 2002 09:53:03 -0600

>

>doc in country Authorises

>

> Brash \ Gavin Lines

>Senior Nurse Supervisor

>Cabinda Gulf Oil Company

>e-mail: Amed2@...

>Telephone: CTN. 8 345 2696

>Via London 020 74878100 Cabinda Ext. 2696

>

> > Thrombolysing

> > > > > >

> > > > > > Any one on the list thrombolysing in the field?

> > > > > >

> > > > > >

>_________________________________________________________________

> > > > > > Join the world's largest e-mail service with MSN Hotmail.

> > > > > > http://www.hotmail.com

> > > > > >

> > > > > >

> > > > > >

> > > > > >

> > > > > > Member Information:

> > > > > >

> > > > > > List owner: Ian Sharpe Owner@...

> > > > > > Editor: Ross Boardman Editor@...

> > > > > >

> > > > > > Post message: egroups

> > > > > > Subscribe: -subscribeegroups

> > > > > > Unsubscribe: -unsubscribeegroups

> > > > > >

> > > > > > Thank you for supporting Remote Medics Online.

> > > > > >

> > > > > >

> > > > > >

> > > > > >

> > > > > >

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No terribly robust but accurate and sensitive it is temp. controlled so we

have it imported by a carrier that can guarantee the cold chain. ( +2 - 8

degrees).

Test kit needs to be brought to room temperature before use 15 - 20C.

Roche will only Guarantee till expiry date and if kept stored at said Temp.

Blood must be anticoagulated from either lithium heparin Tube or EDTA. the

test also comes with a small syringe marked to 15 ul for the test it is

extremely easy to use.

Troponin T is first released in the blood 2 hours after Myocardial pain so

may be negative if MI early.

That is about all I know, DHL now Guarantee Cold chain supplied ( as well as

lab specimens)

Brash \ Gavin Lines

Senior Nurse Supervisor

Cabinda Gulf Oil Company

e-mail: Amed2@...

Telephone: CTN. 8 345 2696

Via London 020 74878100 Cabinda Ext. 2696

> Thrombolysing

> > > > > > >

> > > > > > > Any one on the list thrombolysing in the field?

> > > > > > >

> > > > > > >

> >_________________________________________________________________

> > > > > > > Join the world's largest e-mail service with MSN Hotmail.

> > > > > > > http://www.hotmail.com

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > > Member Information:

> > > > > > >

> > > > > > > List owner: Ian Sharpe Owner@...

> > > > > > > Editor: Ross Boardman Editor@...

> > > > > > >

> > > > > > > Post message: egroups

> > > > > > > Subscribe: -subscribeegroups

> > > > > > > Unsubscribe: -unsubscribeegroups

> > > > > > >

> > > > > > > Thank you for supporting Remote Medics Online.

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >

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Ian

This is quite new stuff for me, further information on Tropinin would be

useful.

Regards Mike

Thrombolysing

> > >

> > > Any one on the list thrombolysing in the field?

> > >

> > > _________________________________________________________________

> > > Join the world's largest e-mail service with MSN Hotmail.

> > > http://www.hotmail.com

> > >

> > >

> > >

> > >

> > > Member Information:

> > >

> > > List owner: Ian Sharpe Owner@...

> > > Editor: Ross Boardman Editor@...

> > >

> > > Post message: egroups

> > > Subscribe: -subscribeegroups

> > > Unsubscribe: -unsubscribeegroups

> > >

> > > Thank you for supporting Remote Medics Online.

> > >

> > >

> > >

> > >

> > >

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Thanks !

Ian

Thrombolysing

> > > >

> > > > Any one on the list thrombolysing in the field?

> > > >

> > > > _________________________________________________________________

> > > > Join the world's largest e-mail service with MSN Hotmail.

> > > > http://www.hotmail.com

> > > >

> > > >

> > > >

> > > >

> > > > Member Information:

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> > > > List owner: Ian Sharpe Owner@...

> > > > Editor: Ross Boardman Editor@...

> > > >

> > > > Post message: egroups

> > > > Subscribe: -subscribeegroups

> > > > Unsubscribe: -unsubscribeegroups

> > > >

> > > > Thank you for supporting Remote Medics Online.

> > > >

> > > >

> > > >

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That is great, thanks for your help. Is there any other marker you are

using as Troponin I or T may not be picked up for 6 hours and some say

continue to test for up to 24hrs.

Do you know of any early marker bed side tests on the market that would

compliment Troponin T?

>From: " Brash, \\ Lines, Gavin (amed2) " <amed2@...>

>Reply-

> " ' ' "

>< >

>Subject: RE: Thrombolysing

>Date: Fri, 1 Feb 2002 08:39:46 -0800

>

>No terribly robust but accurate and sensitive it is temp. controlled so we

>have it imported by a carrier that can guarantee the cold chain. ( +2 - 8

>degrees).

>

>Test kit needs to be brought to room temperature before use 15 - 20C.

>

>Roche will only Guarantee till expiry date and if kept stored at said Temp.

>Blood must be anticoagulated from either lithium heparin Tube or EDTA.

>the

>test also comes with a small syringe marked to 15 ul for the test it is

>extremely easy to use.

>

>Tropin Tis first released in the blood 2 hours after Myocardial pain so

>may be negative if MI early.

>

>That is about all I know, DHL now Guarantee Cold chain supplied ( as well

>as

>lab specimens)

>

>

>

> Brash \ Gavin Lines

>Senior Nurse Supervisor

>Cabinda Gulf Oil Company

>e-mail: Amed2@...

>Telephone: CTN. 8 345 2696

>Via London 020 74878100 Cabinda Ext. 2696

>

> > Thrombolysing

> > > > > > > >

> > > > > > > > Any one on the list thrombolysing in the field?

> > > > > > > >

> > > > > > > >

> > >_________________________________________________________________

> > > > > > > > Join the world's largest e-mail service with MSN Hotmail.

> > > > > > > > http://www.hotmail.com

> > > > > > > >

> > > > > > > >

> > > > > > > >

> > > > > > > >

> > > > > > > > Member Information:

> > > > > > > >

> > > > > > > > List owner: Ian Sharpe Owner@...

> > > > > > > > Editor: Ross Boardman Editor@...

> > > > > > > >

> > > > > > > > Post message: egroups

> > > > > > > > Subscribe: -subscribeegroups

> > > > > > > > Unsubscribe: -unsubscribeegroups

> > > > > > > >

> > > > > > > > Thank you for supporting Remote Medics Online.

> > > > > > > >

> > > > > > > >

> > > > > > > >

> > > > > > > >

> > > > > > > >

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CK/MB is typical enzyme release with AMIs, and this test is run

concurrently with Troponin T. The CK/MB testing is pretty useful

although it's less specific that Troponin, and I don't know if a bedside

test is available. Troponin remains the " gold standard " in assessing

myocardial damage.

Larry

gordon scott wrote:

>

> That is great, thanks for your help. Is there any other marker you

> are

> using as Troponin I or T may not be picked up for 6 hours and some say

>

> continue to test for up to 24hrs.

>

> Do you know of any early marker bed side tests on the market that

> would

> compliment Troponin T?

>

> >From: " Brash, \\ Lines, Gavin (amed2) "

> <amed2@...>

> >Reply-

> > " ' ' "

> >< >

> >Subject: RE: Thrombolysing

> >Date: Fri, 1 Feb 2002 08:39:46 -0800

> >

> >No terribly robust but accurate and sensitive it is temp. controlled

> so we

> >have it imported by a carrier that can guarantee the cold chain. ( +2

> - 8

> >degrees).

> >

> >Test kit needs to be brought to room temperature before use 15 - 20C.

> >

> >Roche will only Guarantee till expiry date and if kept stored at said

> Temp.

> >Blood must be anticoagulated from either lithium heparin Tube or

> EDTA.

> >the

> >test also comes with a small syringe marked to 15 ul for the test it

> is

> >extremely easy to use.

> >

> >Tropin Tis first released in the blood 2 hours after Myocardial pain

> so

> >may be negative if MI early.

> >

> >That is about all I know, DHL now Guarantee Cold chain supplied ( as

> well

> >as

> >lab specimens)

> >

> >

> >

> > Brash \ Gavin Lines

> >Senior Nurse Supervisor

> >Cabinda Gulf Oil Company

> >e-mail: Amed2@...

> >Telephone: CTN. 8 345 2696

> >Via London 020 74878100 Cabinda Ext. 2696

> >

> > > Thrombolysing

> > > > > > > > >

> > > > > > > > > Any one on the list thrombolysing in the field?

> > > > > > > > >

> > > > > > > > >

> > > >_________________________________________________________________

> > > > > > > > > Join the world's largest e-mail service with MSN

> Hotmail.

> > > > > > > > > http://www.hotmail.com

> > > > > > > > >

> > > > > > > > >

> > > > > > > > >

> > > > > > > > >

> > > > > > > > > Member Information:

> > > > > > > > >

> > > > > > > > > List owner: Ian Sharpe Owner@...

> > > > > > > > > Editor: Ross Boardman Editor@...

> > > > > > > > >

> > > > > > > > > Post message: egroups

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> > > > > > > > > Unsubscribe:

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> > > > > > > > >

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> > > > > > > > >

> > > > > > > > >

> > > > > > > > >

> > > > > > > > >

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CK and it's ISO ENZYME MB ... CKmb as far as I know has no bedside test for

this... If your willing to shell out you could get a reflotron ( by Roche)

about 5 grand, This has test strips for CK and CKmb ( as well as about 30

other test strips for U's & E's LFT's etc) It's available from Roche or from

Porter Nash Wigmore street London.

Tropinin is the gold standard for bedside testing, However.. Again I stress

that with history Pain and ecg changes we do not wait for Enzymes, They are

handy for that Sigh of relief after you have given the thrombolitic.

Well Chaps, I am outta here soon back to old Blighty, Keep up the chit chat

as it annoys the hell out of my alternate :-)

Brash \ Gavin Lines

Senior Nurse Supervisor

Cabinda Gulf Oil Company

e-mail: Amed2@...

Telephone: CTN. 8 345 2696

Via London 020 74878100 Cabinda Ext. 2696

> Thrombolysing

> > > > > > > > > >

> > > > > > > > > > Any one on the list thrombolysing in the field?

> > > > > > > > > >

> > > > > > > > > >

> > > > >_________________________________________________________________

> > > > > > > > > > Join the world's largest e-mail service with MSN

> > Hotmail.

> > > > > > > > > > http://www.hotmail.com

> > > > > > > > > >

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> > > > > > > > > >

> > > > > > > > > > Member Information:

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> > > > > > > > > > List owner: Ian Sharpe Owner@...

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> > > > > > > > > > Post message: egroups

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> > > > > > > > > > Thank you for supporting Remote Medics Online.

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See you on the 18th , in sunny Arbroath, the preverbial armpit of the

North East, ( and I should know I used to work in A & E there!!)

Bring Beer tokens with you!!

I'm back to blighty later on today.

Regards

Nick Farrell

Thrombolysing

> > > > > > > > > >

> > > > > > > > > > Any one on the list thrombolysing in the field?

> > > > > > > > > >

> > > > > > > > > >

> > > > >_________________________________________________________________

> > > > > > > > > > Join the world's largest e-mail service with MSN

> > Hotmail.

> > > > > > > > > > http://www.hotmail.com

> > > > > > > > > >

> > > > > > > > > >

> > > > > > > > > >

> > > > > > > > > >

> > > > > > > > > > Member Information:

> > > > > > > > > >

> > > > > > > > > > List owner: Ian Sharpe Owner@...

> > > > > > > > > > Editor: Ross Boardman Editor@...

> > > > > > > > > >

> > > > > > > > > > Post message: egroups

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Nick,

No sweat would not dream of coming without an adequate supply of Beer

tokens, As your from that neck of the woods you should know some pretty good

watering holes. Staying at the Seaforth.... I hear it's not bad breakfast

is good and the bar is good too

Brash \ Gavin Lines

Senior Nurse Supervisor

Cabinda Gulf Oil Company

e-mail: Amed2@...

Telephone: CTN. 8 345 2696

Via London 020 74878100 Cabinda Ext. 2696

> Thrombolysing

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Cheers .

>From: " Brash, \\ Lines, Gavin (amed2) " <amed2@...>

>Reply-

> " ' ' "

>< >

>Subject: RE: Thrombolysing

>Date: Mon, 4 Feb 2002 21:07:09 -0800

>

>CK and it's ISO ENZYME MB ... CKmb as far as I know has no bedside test for

>this... If your willing to shell out you could get a reflotron ( by Roche)

>about 5 grand, This has test strips for CK and CKmb ( as well as about 30

>other test strips for U's & E's LFT's etc) It's available from Roche or

>from

>Porter Nash Wigmore street London.

>

>Tropinin is the gold standard for bedside testing, However.. Again I stress

>that with history Pain and ecg changes we do not wait for Enzymes, They are

>handy for that Sigh of relief after you have given the thrombolitic.

>

>Well Chaps, I am outta here soon back to old Blighty, Keep up the chit

>chat

>as it annoys the hell out of my alternate :-)

>

>

>

> Brash \ Gavin Lines

>Senior Nurse Supervisor

>Cabinda Gulf Oil Company

>e-mail: Amed2@...

>Telephone: CTN. 8 345 2696

>Via London 020 74878100 Cabinda Ext. 2696

>

> > Thrombolysing

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> > > > > > > > > > > Any one on the list thrombolysing in the field?

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I can check but I vaguely remember CK not being of much use in the initial

management as it can take upto 24 hours to show where as the Trop T is a lot

quicker indication??

Can't remember where I heard it but I'll check and come back to you,

Ian

Thrombolysing

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Yes... But CKmb is Cardiac specific

Brash \ Gavin Lines

Senior Nurse Supervisor

Cabinda Gulf Oil Company

e-mail: Amed2@...

Telephone: CTN. 8 345 2696

Via London 020 74878100 Cabinda Ext. 2696

> Re: Thrombolysing

>

> You 're right CK can take as long as 24hrs, Tropin is the way ahead for

> cardiac specific, as CK is released when any muscle tissue is damaged /

> dies.

>

> Ian H

>

>

>

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I used to work in A & E, and the cardiac enzyme that

would be asked for first would be Trophin levels. I

can't remember why. CK-MB will appear within 6hrs of

myocardial damage and stay raised for about 48hrs.

Leanne

--- Owner@... wrote:

> I can check but I vaguely remember CK not being of

> much use in the initial

> management as it can take upto 24 hours to show

> where as the Trop T is a lot

> quicker indication??

>

> Can't remember where I heard it but I'll check and

> come back to you,

>

> Ian

>

> RE:

> Thrombolysing

> > > > > >Date: Fri, 1 Feb 2002 09:53:03 -0600

> > > > > >

> > > > > >doc in country Authorises

> > > > > >

> > > > > > Brash \ Gavin Lines

> > > > > >Senior Nurse Supervisor

> > > > > >Cabinda Gulf Oil Company

> > > > > >e-mail: Amed2@...

> > > > > >Telephone: CTN. 8 345 2696

> > > > > >Via London 020 74878100 Cabinda Ext. 2696

> > > > > >

> > > > > > > -----Original Message-----

> > > > > > > From: gordon scott

> [sMTP:gordonscott18@...]

> > > > > > > Sent: 01 February, 2002 2:27 PM

> > > > > > > To:

>

>

=== message truncated ===

__________________________________________________

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CKMB (the cardiac specific enzyme, and not CK, the more general enzyme)

will show up earlier than Troponin T. CKMB will show in about 2 hours

while it takes Troponin T about 6 hours.

CKMB will show up earlier which is a good thing and is specific to

cardiac muscle, but it's less specific than Trop T. Trop T is more

sensitive, but shows up later. And on the other end of the time frames,

CKMB will return to normal in about 24-36 hours while Trop T stays

elevated for up to 2 weeks.

So...a positive Trop T can mean an MI that is between 6 hours and 14

days old. Add CKMB and, if positive, you can narrow it down to a 6-36

hour window. A positive CKMB and a negative Trop can mean an MI that it

2-6 hours old.

Obviously the EKG and clinical picture have to be considered in all of

this.

Larry

http://home.maine.rr.com/lat/serum-markers.jpg

Owner@... wrote:

>

> I can check but I vaguely remember CK not being of much use in the

> initial

> management as it can take upto 24 hours to show where as the Trop T is

> a lot

> quicker indication??

>

> Can't remember where I heard it but I'll check and come back to you,

>

> Ian

>

> Thrombolysing

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