Vaccinating children younger than age 2 with the pneumococcal vaccine linked to less hospitalizations

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Vaccinating children younger than age 2 with the pneumococcal vaccine linked

to less hospitalizations

Child Health News

Published: Tuesday, 4-Dec-2007

Vaccinating children younger than age 2 with the pneumococcal vaccine

appears to be associated with decreased hospitalizations from pneumonia and

reduced health care expenses, according to a report in the December issue of

Archives of Pediatrics & Adolescent Medicine.

Pneumonia is the leading cause of childhood illness and death worldwide,

accounting for 2 million childhood deaths per year, mainly in developing

countries, according to background information in the article. In 2000,

American children began receiving the 7-valent pneumococcal conjugate

vaccine (PCV7)-which protects against pneumococcal pneumonia, caused by the

Streptococcus pneumoniae bacteria-as part of the routine immunization

schedule. This vaccine is recommended for all children age 2 months to 23

months and children age 24 months to 59 months who are at increased risk for

pneumococcal disease. The number of children age 19 to 35 months receiving

three or more doses increased from 41 percent in 2002 to 83 percent in 2005.

Fangjun Zhou, Ph.D., and colleagues at the Centers for Disease Control and

Prevention, Atlanta, analyzed health records from a database of

approximately 40 large employers each year from 1997 to 2004. The

researchers used claims data and coding from hospitals and physician visits

to determine the number and cost of health care visits due to all-cause and

pneumococcal pneumonia. More than 40,000 children younger than age 2 are

represented in the database each year.

" Comparing the rates in 2004 with those in the baseline period of 1997 to

1999 among children younger than 2 years, hospitalizations due to all-cause

pneumonia declined from 11.5 to 5.5 per 1,000 children (52.4 percent

decline) and ambulatory [outpatient] visits due to all-cause pneumonia

declined from 99.3 to 58.5 per 1,000 children (41.1 percent decline), " the

authors write. " Rates of hospitalization due to pneumococcal pneumonia

declined from 0.6 to 0.3 per 1,000 children (57.6 percent decline) and rates

of ambulatory visits declined from 1.7 to 0.9 per 1,000 children (46.9

percent decline). "

" These results add to the growing evidence base of benefits of PCV7 vaccination

and suggest an important role for the vaccine in reducing the burden of

pneumonia and associated medical costs, " the authors conclude.