[Surveillance of acute flaccid paralysis in Belarus]

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Zh Mikrobiol Epidemiol Immunobiol. ; (2):24-31 17523475

[surveillance of acute flaccid paralysis in Belarus]

[My paper] E O Samoi(lovich , M A Ermolovich , I F Kotova , E Iu

Svirchevskaia , V P Shimanovich , A K Kozhemiakin , I I Protas , E V Fel'dman

The ten-years experience of acute flaccid paralysis (AFP) surveillance in

Belarus has been summarized. Among 456 AFP cases reported from 1996 to

2005, 11 were classified as vaccine-associated paralytic poliomyelitis

(VAPP), 445--as non-polio AFP. The risk of VAPP for the period 1996-2001

was 1 case per 745,000 used doses of oral poliovaccine (OPV). For the

recipients of OPV the risk was 1 case per 911,700 doses and for the

first-dose recipients--1 case per 96,000 doses. The high incidence of VAPP

was a reason for implementation of sequential polio vaccination schedule in

2000. Guillain-Barre syndrome dominated among non-polio AFP (39.3% of

cases); more rare were traumatic neuritis (27.9% of cases), transient

monoparalysis (12.1%), myelitis (7.6%). Non-polio AFP differed from VAPP by

following epidemiological and virological characteristics: predominance of

previously repeatedly vaccinated against poliomyelitis; development of

paralysis in long-term period after vaccination; isolation of non-polio

viruses belonged to three serotypes of sackie B viruses (B1, B4, B6) and

six serotypes of Echo viruses (6, 7, 11, 14, 24, 25) in 8.1% of cases;

absence of typical for polio residual paralyses in patients who excreted

vaccine polioviruses.

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Sheri Nakken, former R.N., MA, Hahnemannian Homeopath

Vaccination Information & Choice Network, Nevada City CA & Wales UK

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