PLAIN water for POTS, Orthostatic Intolerance or dysautonomia

[Guest guest]

I was doing a little research today preparing for a doctor's appt and I ran

across this article which discusses PLAIN water increasing blood pressure vs

Saline. Interesting as increased water and increased salt are treatments for

hypovolemia.

http://www.mc.vanderbilt.edu/reporter/index.html?ID=9047

" Although water does not significantly raise blood pressure in healthy young

subjects with intact baroreflexes, the investigators found that it does increase

sympathetic nervous system activity and constrict blood vessels (which prevents

pooling of blood in the extremities).

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The investigators ultimately determined that water dilutes the plasma in the

blood vessels leading away from the duodenum and that this short-lived reduction

in salt concentration (hypo-osmolality) is responsible for water's blood

pressure-raising (pressor) effect. They implicated a protein called Trpv4 in the

mechanism: mice lacking the Trpv4 gene did not have a pressor response to

water. "

Marti