Re: Re: Cortisol and DHEA Testing--NIL

[Guest guest]

Hi Sue

Dhea sulfate is blood test.

Yes, cortisol is best measured by saliva test but you will probably need to find

a naturopath to interpret the results.AFAIK many endocrinologists do not accept

saliva test.

Saliva test will check your cortisol levels at four different times of a day.24

hour urinary free cortisol test is accepted by endos but It measures your total

urinary free cortisol for 24 hour time period.Variations in cortisol levels will

not be observable there.For example if you have high cortisol in the morning and

noon and low in the afternoon and evening your total urinary free cortisol test

may come up normal.24 hour urinary free cortisol test will be meaningful for CFS

patient if person is low in cortisol whole day.

best wishes

nil

Re: Cortisol and DHEA Testing--NIL

Nil,

You wrote " DHEA So4 test gives good picture of DHEA status. " Is this a blood

test or a saliva test?

I have lot of cognitive trouble. Does the information mean that Cortisol is

best measured through saliva then?

Thanks again!

Sue

[Guest guest]

Hi Sue

If you decide to take the saliva test I may be able to tell you if you have

adrenal exhaustion or not.But I can not tell you which supplements to take and

how much. For that you need to find a naturopath or an endocrinologist who

accepts saliva tests.

For saliva testing check site of Diagnos techs.

http://www.diagnostechs.com/Home.aspx

you may also wish to join group 's disease

s_Disease/

There may be some US citizen PWC's there who were diagnosed by an

endocrinologist.They might be able to give you some helpful info.

Best wishes

nil

Re: Cortisol and DHEA Testing--NIL

Nil,

You wrote " DHEA So4 test gives good picture of DHEA status. " Is this a blood

test or a saliva test?

I have lot of cognitive trouble. Does the information mean that Cortisol is

best measured through saliva then?

Thanks again!

Sue

>

> Thanks to all who have answered my burning feet Inquiry.

>

> Cortisol is in two forms in the body.Free cortisol plus bound cortisol.Some

cortisol is bound by cortisol binding globulins and is not available for use.

> It has been observed that CBG levels of PWC's are higher than normal

population.

> " The SST relies on serum total cortisol responses. A

>

> large proportion of serum total cortisol is bound to

>

> CBG (80-90%). Thus, serum total cortisol levels are

>

> affected by variation in CBG. It has been shown that

>

> the changes in serum total cortisol levels do not correlate

>

> with cortisol production rates unless differences in

>

> CBG are corrected for (4). However, CBG is not routinely

>

> considered in the interpretation of total cortisol

>

> measurements. Our data suggest that CBG is important

>

> for the correct interpretation of dynamic tests of the

>

> HPA axis. "

>

> http://www.eje-online.org/content/146/2/231.full.pdf+html

>

> There was another article which stated that PWC's had higher CBG levels but

I could not find it at the moment.

> Serum cortisol test measures total cortisol level which is free plus

bounded.Therefore it does not give correct picture of available cortisol. Saliva

test gives directly free cortisol which is preferable but than there is problem

of finding and MD who will interpret and use it. You may need to see naturopath

for that.

>

> 24 hour urinary free cortisol test may also give better picture than serum

cortisol test.

>

> DHEA So4 test gives good picture of DHEA status.

> Best wishes

> nil

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