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Hi Gordon,

How did your trial of cholestyramine go?

I have a friend in California who is on the RVK methylation protocol. She says

she has seen significant improvement.

Tim

Hi All ....I tend to come here to share experiences and ideas for those looking

for a treatment in to their cause of CFS/ME symptoms.

Has anyone tried the Rich Van Konynenburge treatment plan out for methylation

cycle block?

http://aboutmecfs.org.violet.arvixe.com/Trt/TrtGSHMethISimple.aspx

http://www.drmyhill.co.uk/wiki/CFS_-_The_Methylation_Cycle

It would be useful to share experiences from those who have tried this or hear

from those keeping a log when trying this protocol.

Regards

Gordon

Leeds

U.K.

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Hi I didn't do very well on Questran (cholestyramine) I tried one sachet a day

for a month and it just seemed to clog up my system (not bowel wise as I took

plenty of vit C) but I just felt very toxic and nauseas. Iv been off it for

2weeks and trying to build up my stamina levels again. I will try very low doses

of the methylation protocol i.e. ActiFolate and Intrinsic B12/Folate which

appear to be the key supplements then add the rest as I go along given that I

don't suffer too much from the first two supplements.

Regards

Gordon

U.K.

(a bit wind blown today from hurricane Collete you sent over from the states)

methylation treatment

Hi Gordon,

How did your trial of cholestyramine go?

I have a friend in California who is on the RVK methylation protocol. She says

she has seen significant improvement.

Tim

Hi All ....I tend to come here to share experiences and ideas for those

looking for a treatment in to their cause of CFS/ME symptoms.

Has anyone tried the Rich Van Konynenburge treatment plan out for methylation

cycle block?

http://aboutmecfs.org.violet.arvixe.com/Trt/TrtGSHMethISimple.aspx

http://www.drmyhill.co.uk/wiki/CFS_-_The_Methylation_Cycle

It would be useful to share experiences from those who have tried this or hear

from those keeping a log when trying this protocol.

Regards

Gordon

Leeds

U.K.

------------------------------------------------------------------------------

No virus found in this message.

Checked by AVG - www.avg.com

Version: 10.0.1392 / Virus Database: 1520/3878 - Release Date: 09/05/11

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Hi, Gordon.

The simplified methylation protocol has been revised. The formulation of

Intrinsi B12/folate was changed by Metametrix, and it no longer contains folinic

acid. Other changes were made to minimize folic acid in the protocol, to make

it more convenient by using drops instead of splitting capsules, and adding

lecithin as an option for those with low cortisol. The most recent version is

pasted below.

Best regards,

Rich

March 30. 2011

SIMPLIFIED TREATMENT APPROACH

FOR LIFTING THE METHYLATION CYCLE BLOCK

IN CHRONIC FATIGUE SYNDROME—March 30, 2011 Revision

Rich Van Konynenburg. Ph.D.

(Based on the full treatment program

developed by Amy Yasko, Ph.D., N.D.

which is used primarily in treating autism [1])

SUPPLEMENTS

1. General Vitamin Neurological Health Formula [2]: Start with one-quarter

tablet and increase dosage as tolerated to 2 tablets daily

2. Hydroxy B12 Mega Drops [3]: 2 drops under the tongue daily

3. MethylMate B [4]: 3 drops under the tongue daily

4. Folinic acid [5]: ¼ capsule daily

5. Phosphatidyl Serine Complex [6]: 1 softgel capsule daily (or lecithin, see

below)

All these supplements can be obtained from http://www.holisticheal.com.

The fourth supplement comes in capsules that contain 800 mcg. It will be

necessary to open the capsules, dump the powder onto a flat surface, and

separate it into quarters using a knife to obtain the daily dose. The powder can

be taken orally with water, with or without food.

These supplements can make some patients sleepy, so in those cases they

take them at bedtime. In general, they can be taken at any time of day, with or

without food.

Phosphatidyl serine can lower cortisol levels. Patients who already have

low evening cortisol levels may wish to substitute lecithin [7] (at one softgel

daily) for supplement number 5 above. Lecithin is also available from

http://www.holisticheal.com.

For those allergic to soy, lecithin from other sources is available.

GO SLOWLY. As the methylation cycle block is lifted, toxins are mobilized

and processed by the body, and this can lead to an exacerbation of symptoms. IF

THIS HAPPENS, try smaller doses, every other day. SLOWLY work up to the full

dosages.

Although this treatment approach consists only of nonprescription

nutritional supplements, a few patients have reported adverse effects while on

it. Therefore, it is necessary that patients be supervised by physicians while

receiving this treatment.

[1] Yasko, Amy, Autism, Pathways to Recovery, Neurological Research Institute,

2009, available from http://www.holisticheal.com or Amazon.

[2] General Vitamin Neurological Health Formula is formulated and supplied by

Holistic Health Consultants LLC.

[3] Hydroxy B12 Mega Drops is a liquid form of hydroxocobalamin (B12), supplied

by Holistic Health Consultants. 2 drops is a dosage of 2,000 mcg.

[4] MethylMate B is a liquid form of (6s)-methyltetrahydrofolate supplied by

Holistic Health Consultants, based on Extrafolate S, a trademark of Gnosis

S.P.A. 3 drops is a dosage of 210 mcg.

[5] Folinic acid is 5-formyltetrahydrofolate. ¼ capsule is a dosage of 200 mcg.

[5] Phosphatidyl Serine Complex is a product of Vitamin Discount Center. 1

softgel is a dosage of 500 mg.

[7] Lecithin is a combination of phospholipids without phosphatidylserine. One

softgel is a dosage of 1,200 mg.

>

> Hi I didn't do very well on Questran (cholestyramine) I tried one sachet a day

for a month and it just seemed to clog up my system (not bowel wise as I took

plenty of vit C) but I just felt very toxic and nauseas. Iv been off it for

2weeks and trying to build up my stamina levels again. I will try very low doses

of the methylation protocol i.e. ActiFolate and Intrinsic B12/Folate which

appear to be the key supplements then add the rest as I go along given that I

don't suffer too much from the first two supplements.

>

> Regards

> Gordon

> U.K.

>

> (a bit wind blown today from hurricane Collete you sent over from the states)

> methylation treatment

>

>

>

> Hi Gordon,

>

> How did your trial of cholestyramine go?

>

> I have a friend in California who is on the RVK methylation protocol. She

says she has seen significant improvement.

>

> Tim

>

> Hi All ....I tend to come here to share experiences and ideas for those

looking for a treatment in to their cause of CFS/ME symptoms.

>

> Has anyone tried the Rich Van Konynenburge treatment plan out for

methylation cycle block?

>

> http://aboutmecfs.org.violet.arvixe.com/Trt/TrtGSHMethISimple.aspx

>

> http://www.drmyhill.co.uk/wiki/CFS_-_The_Methylation_Cycle

>

> It would be useful to share experiences from those who have tried this or

hear from those keeping a log when trying this protocol.

>

> Regards

> Gordon

> Leeds

> U.K.

>

>

>

>

> ------------------------------------------------------------------------------

>

> No virus found in this message.

> Checked by AVG - www.avg.com

> Version: 10.0.1392 / Virus Database: 1520/3878 - Release Date: 09/05/11

>

>

>

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I'm also in the UK and just trying this protocol. You can get all Holisticheal

supplements here in the UK from http://www.vitaminsuk.com/. They do not have

them on their website but they can supply if you ring them. Also if you say

that you are a member of Action for ME (no proof required) then you get 10%

discount.

> >

> > Hi I didn't do very well on Questran (cholestyramine) I tried one sachet a

day for a month and it just seemed to clog up my system (not bowel wise as I

took plenty of vit C) but I just felt very toxic and nauseas. Iv been off it for

2weeks and trying to build up my stamina levels again. I will try very low doses

of the methylation protocol i.e. ActiFolate and Intrinsic B12/Folate which

appear to be the key supplements then add the rest as I go along given that I

don't suffer too much from the first two supplements.

> >

> > Regards

> > Gordon

> > U.K.

> >

> > (a bit wind blown today from hurricane Collete you sent over from the

states)

> > methylation treatment

> >

> >

> >

> > Hi Gordon,

> >

> > How did your trial of cholestyramine go?

> >

> > I have a friend in California who is on the RVK methylation protocol. She

says she has seen significant improvement.

> >

> > Tim

> >

> > Hi All ....I tend to come here to share experiences and ideas for those

looking for a treatment in to their cause of CFS/ME symptoms.

> >

> > Has anyone tried the Rich Van Konynenburge treatment plan out for

methylation cycle block?

> >

> > http://aboutmecfs.org.violet.arvixe.com/Trt/TrtGSHMethISimple.aspx

> >

> > http://www.drmyhill.co.uk/wiki/CFS_-_The_Methylation_Cycle

> >

> > It would be useful to share experiences from those who have tried this or

hear from those keeping a log when trying this protocol.

> >

> > Regards

> > Gordon

> > Leeds

> > U.K.

> >

> >

> >

> >

> >

------------------------------------------------------------------------------

> >

> > No virus found in this message.

> > Checked by AVG - www.avg.com

> > Version: 10.0.1392 / Virus Database: 1520/3878 - Release Date: 09/05/11

> >

> >

> >

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  • 2 weeks later...

Reposted for reference:

Latest Simplified protocol:

HTH,

Marti

> >

> > Hi I didn't do very well on Questran (cholestyramine) I tried one sachet a

day for a month and it just seemed to clog up my system (not bowel wise as I

took plenty of vit C) but I just felt very toxic and nauseas. Iv been off it for

2weeks and trying to build up my stamina levels again. I will try very low doses

of the methylation protocol i.e. ActiFolate and Intrinsic B12/Folate which

appear to be the key supplements then add the rest as I go along given that I

don't suffer too much from the first two supplements.

> >

> > Regards

> > Gordon

> > U.K.

> >

> > (a bit wind blown today from hurricane Collete you sent over from the

states)

> > methylation treatment

> >

> >

> >

> > Hi Gordon,

> >

> > How did your trial of cholestyramine go?

> >

> > I have a friend in California who is on the RVK methylation protocol. She

says she has seen significant improvement.

> >

> > Tim

> >

> > Hi All ....I tend to come here to share experiences and ideas for those

looking for a treatment in to their cause of CFS/ME symptoms.

> >

> > Has anyone tried the Rich Van Konynenburge treatment plan out for

methylation cycle block?

> >

> > http://aboutmecfs.org.violet.arvixe.com/Trt/TrtGSHMethISimple.aspx

> >

> > http://www.drmyhill.co.uk/wiki/CFS_-_The_Methylation_Cycle

> >

> > It would be useful to share experiences from those who have tried this or

hear from those keeping a log when trying this protocol.

> >

> > Regards

> > Gordon

> > Leeds

> > U.K.

> >

> >

> >

> >

> >

------------------------------------------------------------------------------

> >

> > No virus found in this message.

> > Checked by AVG - www.avg.com

> > Version: 10.0.1392 / Virus Database: 1520/3878 - Release Date: 09/05/11

> >

> >

> >

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Thanks - do you know why methylmate a is avoided? Is it covered via other supps?

Or is it the cost think a bottle is about 100 dollars...

Sent using BlackBerry® from Orange

Re: methylation treatment

Reposted for reference:

Latest Simplified protocol:

HTH,

Marti

> >

> > Hi I didn't do very well on Questran (cholestyramine) I tried one sachet a

day for a month and it just seemed to clog up my system (not bowel wise as I

took plenty of vit C) but I just felt very toxic and nauseas. Iv been off it for

2weeks and trying to build up my stamina levels again. I will try very low doses

of the methylation protocol i.e. ActiFolate and Intrinsic B12/Folate which

appear to be the key supplements then add the rest as I go along given that I

don't suffer too much from the first two supplements.

> >

> > Regards

> > Gordon

> > U.K.

> >

> > (a bit wind blown today from hurricane Collete you sent over from the

states)

> > methylation treatment

> >

> >

> >

> > Hi Gordon,

> >

> > How did your trial of cholestyramine go?

> >

> > I have a friend in California who is on the RVK methylation protocol. She

says she has seen significant improvement.

> >

> > Tim

> >

> > Hi All ....I tend to come here to share experiences and ideas for those

looking for a treatment in to their cause of CFS/ME symptoms.

> >

> > Has anyone tried the Rich Van Konynenburge treatment plan out for

methylation cycle block?

> >

> > http://aboutmecfs.org.violet.arvixe.com/Trt/TrtGSHMethISimple.aspx

> >

> > http://www.drmyhill.co.uk/wiki/CFS_-_The_Methylation_Cycle

> >

> > It would be useful to share experiences from those who have tried this or

hear from those keeping a log when trying this protocol.

> >

> > Regards

> > Gordon

> > Leeds

> > U.K.

> >

> >

> >

> >

> >

------------------------------------------------------------------------------

> >

> > No virus found in this message.

> > Checked by AVG - www.avg.com

> > Version: 10.0.1392 / Virus Database: 1520/3878 - Release Date: 09/05/11

> >

> >

> >

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thanks for that info...if I order these again I will check the site out...

I am taking what i believe to be the most potent supplements first of the 5. I

have found that the Folapro is pretty potent even taking a 1/4 of the tablet was

giving me some mild headaches and has interfered with my sleeping patterns also

strong smell from body wastes... I am now taking about 1/8th of the Folapro

tablet I'm probably ok with the Intrinsi b12/folate and sublingual b12 I just

got the Phosphatidyl Serine this morning and waiting for the multi

mineral/vitamin from Holisticheal to come through.

I am taking these in stages as I find it useful to know which is effecting me

and in what ways.

Let me know how you get on

Regards

Gordon

methylation treatment

> >

> >

> >

> > Hi Gordon,

> >

> > How did your trial of cholestyramine go?

> >

> > I have a friend in California who is on the RVK methylation protocol. She

says she has seen significant improvement.

> >

> > Tim

> >

> > Hi All ....I tend to come here to share experiences and ideas for those

looking for a treatment in to their cause of CFS/ME symptoms.

> >

> > Has anyone tried the Rich Van Konynenburge treatment plan out for

methylation cycle block?

> >

> > http://aboutmecfs.org.violet.arvixe.com/Trt/TrtGSHMethISimple.aspx

> >

> > http://www.drmyhill.co.uk/wiki/CFS_-_The_Methylation_Cycle

> >

> > It would be useful to share experiences from those who have tried this or

hear from those keeping a log when trying this protocol.

> >

> > Regards

> > Gordon

> > Leeds

> > U.K.

> >

> >

> >

> >

> > ----------------------------------------------------------

> >

> > No virus found in this message.

> > Checked by AVG - www.avg.com

> > Version: 10.0.1392 / Virus Database: 1520/3878 - Release Date: 09/05/11

> >

> >

> >

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  • 4 months later...

Hi All

I think I am benefiting from the methylation treatment after starting it last

September and building up the number of supplements slowly particularly the

Phosphatidyl Serine Complex which I had to take a 1/4 of a tablet alternate

days. I can now take a full tablet.

I am about to order the Phosphatidyl Serine Complex again and have noted big

differences in cost between the 500mg gel type that contain 100mg of

Phosphatidyl Serine and essential fatty acids.

http://www.vitamindiscountcenter.net/servlet/the-3243/787500053438/Detail

The tablet version also contains 100mg of Phosphatidyl Serine but at a third of

the cost.

Phosphatidyl Serine 100mg (20%), Ginkgo Biloba Extract 8mg (50:1) equivalent to

400mg, Korean Ginseng 8mg (25:1) equivalent to 200mg, Dicalcium Phosphate,

Microcrystalline Cellulose, Magnesium Stearate.

Is there any advantage to buying the gel complex version over the tablet version

of Phosphatidyl Serine???

Your replies would be very welcome.

Gordon

Leeds

UK

methylation treatment

> >

> >

> >

> > Hi Gordon,

> >

> > How did your trial of cholestyramine go?

> >

> > I have a friend in California who is on the RVK methylation protocol. She

says she has seen significant improvement.

> >

> > Tim

> >

> > Hi All ....I tend to come here to share experiences and ideas for those

looking for a treatment in to their cause of CFS/ME symptoms.

> >

> > Has anyone tried the Rich Van Konynenburge treatment plan out for

methylation cycle block?

> >

> > http://aboutmecfs.org.violet.arvixe.com/Trt/TrtGSHMethISimple.aspx

> >

> > http://www.drmyhill.co.uk/wiki/CFS_-_The_Methylation_Cycle

> >

> > It would be useful to share experiences from those who have tried this or

hear from those keeping a log when trying this protocol.

> >

> > Regards

> > Gordon

> > Leeds

> > U.K.

> >

> >

> >

> >

> > ----------------------------------------------------------

> >

> > No virus found in this message.

> > Checked by AVG - www.avg.com

> > Version: 10.0.1392 / Virus Database: 1520/3878 - Release Date: 09/05/11

> >

> >

> >

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