Re: To much of a good thing?

[Guest guest]

Yes, lots of things can go wrong, and much more than histamine levels need to be

tested for. I'm just beginning to learn about this stuff myself. I did the

simplified protocol under the guidance of a an MD and just that caused major

detox dumping, but the CFS had a very slight improvement (which is good for me,

as most things don't do anything or make me worse). So now I've decided to have

my genetics tested by Amy Yasko

(http://www.holisticheal.com/health-tests/nutrigenomic-testing) for very

specific genetic problems related to the methylation cycle and enlisted the help

of an MD experienced in these things.

Reading about the Yasko protocol will give you all the answers to your

questions, but it takes time to wrap your brain around it. Like getting a PHD

in chemistry. That's why I'm enlisted help from professionals.

>

> When adding in all this methylaion support - does there come a time when you

can be overdoing it?

>

> For example can you go from poor methylation, then add support, to to much

methylation. I know one issue with to much methylation is low histamine that can

lead to low stomach acid and thus issues like candida/bacteria/zinc deficiency.

>

> So how can you test if you are overdoing it? Is it by monitoring histamine

levels ? Or more detailed testing?

>

[Guest guest]

I've been doing the Yasko Protocol for over a year now. I believe it's the best

science out there, but it's definitely slow going.

> >

> > When adding in all this methylaion support - does there come a time when you

can be overdoing it?

> >

> > For example can you go from poor methylation, then add support, to to much

methylation. I know one issue with to much methylation is low histamine that can

lead to low stomach acid and thus issues like candida/bacteria/zinc deficiency.

> >

> > So how can you test if you are overdoing it? Is it by monitoring histamine

levels ? Or more detailed testing?

> >

>

[Guest guest]

To whoever might be interested,

I did the full Yasko protocol for about 2 1/2 years. I improved

perhaps 20% over that time. I discontinued it because I just couldn't

face taking 80 different pills and/or supplements a day anymore, and

for me the cost was prohibitive. The 20% improvement was not worth the

cost in time, money, and aggravation in taking all those pills.

However, I do believe that Dr Yasko is truly on to something, and that

there's good scientific rationale behind her program. I wish that some

larger institution would take on her protocol and do the studies and

investigations necessary to validate and fine-tune it.

For me, I felt the Yasko protocol didn't hurt me, and probably did

help a little bit, but wasn't zeroing in on whatever the central

problem was in my own illness.

I've been seeing Dr Klimas in Miami for the last year or so, and

she has been treating me with an immune modulator. My body's reaction

to that drug is similar to my reactions to the several things in the

Yasko protocol that seemed to have an effect on me, i.e., flu-like

symptoms. That tells me my illness is somehow connected to the immune

system. Could be autoimmune, could be " stealth " pathogens hanging

around my body, could be a problem with chronic disregulation of one

or more of the body's system, i.e., a problem with homeostasis.

I don't know what the answer is yet. However, even with the

disappointment of XMRV not turning out to be " the " answer, I think

there are several very good large studies just getting underway that

will shed more light on the subject, not to mention the interesting

news out of Norway about Rituximab

(http://esme-eu.com/treatment/a-drug-for-me-cfs-the-rituximab-story-article468-1\

10.html

).

I do think I am a little better than I was five years ago, as I had a

busy day yesterday with holiday-related activities (a concert, then a

holiday party a friend's house) and was able to get through it okay. I

made a point of staying hydrated with an electrolyte drink during the

day, and I'm having a day-after " recovery day " at home where all I'm

doing is sleeping and eating. But I'm nowhere as near crashed as I

would have been several years ago, and I really appreciate that. As

long as I pace myself, I can enjoy life a bit more.

Well, okay, I thought I was going to be able to water the houseplants

today, and that's right out, but still and all, progress is being made.

Best wishes to all of my fellow travelers,

Marcia on

in Salem, Massachusetts

On Dec 4, 2011, at 3:05 PM, valkitty1 wrote:

> I've been doing the Yasko Protocol for over a year now. I believe

> it's the best science out there, but it's definitely slow going.

>

>

>

> > >

> > > When adding in all this methylaion support - does there come a

> time when you can be overdoing it?

> > >

> > > For example can you go from poor methylation, then add support,

> to to much methylation. I know one issue with to much methylation is

> low histamine that can lead to low stomach acid and thus issues like

> candida/bacteria/zinc deficiency.

> > >

> > > So how can you test if you are overdoing it? Is it by monitoring

> histamine levels ? Or more detailed testing?

> > >

> >

>

>

[Guest guest]

marcia,

what immune modulator are u on?

thanks.

[Guest guest]

I'm on Immunovir. Dr Klimas has been approved to Rx it for U.S.

patients, who then order it from Canada, since it's not generally

available in the U.S.

The regimen is 3 months on, then 3 months off, repeat as the doctor

sees fit. Within the 3 months when taking it, I alternate weeks

between 3 pills a day and 6 pills a day, with weekends off.

Dr Klimas said my blood test immune markers looked much better after

the first round, although I can't say I was feeling much different.

I'll have another round of blood tests in about 6 months and probably

a follow-up office visit at that time.

Marcia on

in Salem, Massachusetts

On Dec 4, 2011, at 9:59 PM, Jim wrote:

> marcia,

>

> what immune modulator are u on?

>

> thanks.

>

[Guest guest]

marcia,

thanks for the reply. tried imunovir which may have helped for a while, but

then stopped. hope u have better success.

jim