Re: New Spanish Treatment patented for CFIDS-elastase inhibitors

[Guest guest]

I have not been following this, but is elastase related to

Ehlers-Danlos syndrome (type 3)?

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===

Bigotry against people with serious diseases is still bigotry.

[Guest guest]

{Noderator: Based on group feedback on the rule against product links, the

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Hi,

I've actually been taking something similar for about 5 years. It's supposed to

reduce your chances of breast cancer. And it reduces inflammation particularly

noticeable in my breast tissue. I have dense tissue with a lot of inflammation,

and it can get pretty painful. Plus all that inflammation raises my risks of

cancer.

I use one by Pure Encapsulations called DIM-PRO 100

https://accutrition.com/shop/product_info.php?products_id=651

I used to use one called BioResponse Dim

http://www.bioresponse.com/Home.asp

I may switch back to this one as I think it works a little better. Also they

have a good write up about their product on that page

They don't mention anything about elastase in their write up.

I will mention I have hyper-mobility. I think it has caused premature

osteoarthritis. Possibly a mild version of ED

best,

ra

>

> I saw a new treatment has been patented for CFIDS/ME

>

> http://www.faqs.org/patents/app/20100331261

>

> If you just google alpha 1 antitrypsin and CFS you get some info on it.

> The inventors are Quintana, Alegra .

> It's on the NCF webpage as well.

>

> I don't understand much about it.

> I understand that something called RNase L in the bodies of people w/CFS is

abnormal. This alpha 1 trypsin is supposed to make it normal...I think (?)

>

> What I do understand is that this alpha-1 trypsin is prepared from human

plasma. The FDA has approved of 3 alpha-1 trypsin products. They are given by

infusion and treatment costs $100,000 a year.

>

> I was wondering if it were possible to get some cheaper substance that could

do the same job. I read that alpha-1 trypsin is an elastase inhibitor and

that raised elastase activity is what is causing the abnormal RNase L in the

body of PWCFS. So I did my own google search for " natural elastase inhibitors "

and got a lot of results with " indole-3-carbinol " in them. Here's just one:

> http://www.pnas.org/content/105/50/19750.full

>

> Indole 3 carbinol is available as a food supplement and supposed to be found

naturally in brocolli and cabbage.

> Now I have too many severe digestive problems to buy and try this this

supplement. If things were better I would have a go. This is just a suggestion

but I wonder if it worthwhile for a PWCFS who can tolerate food supplements to

try this and let us know how / if it helps. It does not look harmful - but I am

just thinking aloud, I don't want to be resposible if someone takes it and finds

they can't tolerate it. I was just wondering about it.

>

> What do others here think of this Spanish research?

>

[Guest guest]

Have you noticed any other improvements in symptoms, like fatigue, from taking

these?

Thanks,

Ellen

>Hi,

I've actually been taking something similar for about 5 years. It's supposed to

reduce your chances of breast cancer. And it reduces inflammation particularly

noticeable in my breast tissue. I have dense tissue with a lot of inflammation,

and it can get pretty painful. Plus all that inflammation raises my risks of

cancer.

I use one by Pure Encapsulations called DIM-PRO 100

https://accutrition.com/shop/product_info.php?products_id=651

I used to use one called BioResponse Dim

http://www.bioresponse.com/Home.asp

I may switch back to this one as I think it works a little better. Also they

have a good write up about their product on that page

They don't mention anything about elastase in their write up.

I will mention I have hyper-mobility. I think it has caused premature

osteoarthritis. Possibly a mild version of ED

best,

ra

[Guest guest]

Yes, a quick google search shows that elastase is related to ED in some way, I

don't know how.

According to a google search elastase inhibitors are used to treat something

called Chronic obstructive pulmonary disease DOPD. This is

a lung desease that makes it is hard to breath.

I think I might have also seen a type of heart desease treated by elsatase

inhibitors somewhere but I am less sure about that (?).

This Spanish study is the first time I have seen elastase inhibitors used for

CFS treatment.

I like your blog by the way.

>

> I have not been following this, but is elastase related to

> Ehlers-Danlos syndrome (type 3)?

>

> --

> The Kafka Pandemic: http://thekafkapandemic.blogspot.com

> I support the Whittemore- Institute (WPI)

> ===

> Bigotry against people with serious diseases is still bigotry.

>

[Guest guest]

EDS and POTS (Postural Orthostatic Tachychardia Syndrome seem to go hand in

hand. You can have POTS and not EDS and vice versa but there seems to be a

correlation.

I have been on the group NCS_F (Neuro Cardiogenic Syncope-Fainting).

NCS_F/?yguid=275214264

Unfortunately, I haven't had made much progress but addressing triggers has been

helpful.

Marti

POTS but no EDS.

> > Yes, a quick google search shows that elastase is related to ED in some way,

> > I don't know how.

>

> I know little about EDS. If it's supposed to be related to one of the

> diseases in question, and supposed to be genetically inherited by some

> mode, I wonder if that means it's a marker for susceptibility, or if

> we're talking about something like gene expression instead. Any

> existing informal wisdom on the list on these possibly very naive

> questions?

>

> > According to a google search elastase inhibitors are used to treat something

> > called Chronic obstructive pulmonary disease DOPD. This is

> > a lung desease that makes it is hard to breath.

> >

> > I think I might have also seen a type of heart desease treated by elsatase

> > inhibitors somewhere but I am less sure about that (?).

>

> Interesting.

>

> > I like your blog by the way.

>

> Thanks!

>

>

>

> --

> The Kafka Pandemic: http://thekafkapandemic.blogspot.com

> I support the Whittemore- Institute (WPI)

> ===

> Bigotry against people with serious diseases is still bigotry.

>