simplified protocol

[Guest guest]

Hi Rich,

Is it fair to say that the full Yasko program has a better chance of yielding

results than your simplified protocol? If so, how much better than 2/3?

Tim

P.S. I recently tested strongly positive on Dr. Chia's Immunoperoxidase

enteroviral stain test, providing the first evidence in a quarter century that I

have a chronic viral infection.

Hi, Joy.

Yes, the full Yasko testing and treatment program is pretty complicated. That

motivated me to try to come up with a simplified protocol. With the help of

Trina, who posts to the cfs_yasko group, I suggested one in early 2007. It has

since been revised three times, but the core of it is still essentially the

same. There are also several other methylation protocol variants recommended by

others. The key aspect of all of them is that they combine high-dose B12 (either

sublingual or by injection) and folate, usually taken orally. There are other

supporting nutrients as well. They differ in the particular forms of B12 and

folate used. The protocol I've suggested includes mostly hydroxocobalamin and

mostly 5L-methyltetrahydrofolate and folinic acid, respectively.

The supplements are all available without a prescription, and I suspect that

quite a few people are just ordering them and trying them. However, my

recommendation is first to take the methylation pathways panel offered by Health

Diagnostics and Research Institute in New Jersey, to see if there is a partial

methylation cycle block and glutathione depletion, and to get baseline data to

use in gauging the progress of treatment later. I also recommend that a person

be monitored by a physician while on this type of treatment, because a small

number of people have reported experiencing serious adverse effects while on it,

even though it consists only of nutritional supplements.

If you want to know more about the panel and the protocol, the information is in

the files section of the cfs_yasko group's website:

CFS_Yasko/

I believe that this type of treatment addresses the core mechanism in ME/CFS,

and that lifting the partial methylation cycle block and restoring glutathione

are essential to recovery. Experience over the past four years has shown that

while this treatment helps most PWCs significantly, it is not the whole story

for treatment that leads to recovery. We have found that some of the factors

that caused the depletion of glutathione initially need to be dealt with

specifically, too. These include toxic mold exposure, Lyme disease and its

coinfections, entrenched viral infections, and large body burdens of toxic heavy

metals. Some of these issues can also develop after the onset of ME/CFS, and may

need to be dealt with directly in that case, also.

We have seen a small number of what are reported to be complete recoveries, at

least to the point that the person is able to work full time and handle exercise

and stress. In these cases, it appears that other issues, such as those I've

listed, were also treated specifically in addition to doing the methylation

treatment.

So that's where things currently stand with the methylation approach, from my

point of view. I had of course hoped that it would be the silver bullet, and

that hasn't turned out to be the case, but it does seem to be one of them!(:-)

Best regards,

Rich

> > > >

> > > > Hi everyone,

> > > >

> > > > Is anyone on the IMMM supplement trial for fatigue?

> > > >

> > > > Curious how it's going. I seemed to have felt a slight relief of fatigue

in the first week. Definitely not placebo as I sank like a rock during a high

stress event (neighbor's pit bull).

> > > >

> > > > I feel like cleaning, have started exercise (okay, shouldn't really be

called that - some leg lifts, some light weights)

> > > >

> > > > Marti

> > > >

> > >

> >

>