Cpn, Biofilms and antibiotic therapy

[Guest guest]

Hi All,

As I mentioned in an earlier message my physician and I discussed our next step

and decided try to eliminate my ridiculous high bacterial infections.

Besides all my active viral infections I also have a high load of bacterial

infections. The most active one is at the moment Cpn or Chlamydia Pneumoniae. It

seems obvious to me that if we started this protocol the others(

MAC(Mycobacterium avium complex), Candida, Giardia, Mycoplasma) would also

suffer or so I hope.

The therapy is developed my dr Stratton who had to stop his research because his

funds dried up and he transferred all his files to the Cpnhelp.org web site.

Although he is not available for consult anymore there is still a wealth of

information there. There are 2 protocols the Wheldon named after dr. Wheldon

from the UK and the Stratton.

The web site says: Work at Vanderbilt University by Stratton et al, extended by

British physician Wheldoni has formulated Combination Antibiotic

Protocolsi (CAPi's) to treat the multiple life phases of Cpn and fully eradicate

this persistent infection.

Dr Wheldon uses Doxycycline, Azithromycin orRoxithromycin, Metronidazolei pulse,

also called Flagyl, an alternative is Tinidazole

dr. Stratton uses: Rifampin, Azithromycin, Metronidazole, Sodium or Calcium

Pyruvate

A description of the protocols can be found here

http://www.cpnhelp.org/treatment_protocols plus a Handbook about Cpn and

treatment.

The Cpn has 3 life stages in one of it's last stages is builds a little factory

in your cells where it can reproduce and closes this off with a biofilm so not

antibiotic can get to it. The outside of the biofilm will harden because other

bacteria and viruses adhere to it and release waste and toxin that harden the

surface.

To be able to kill the Cpn bacteria we need to brake open the biofilm. We do

this by taking a newly developed enzyme called Interfase. It is developed by

Klaire labs* and sold as a supplement up till now. The follow up product to use

after Interfase is Interfase Plus and that contains

EDTA(ethylenediaminetetraaceticacid) http://en.wikipedia.org/wiki/EDTA

On February 26, 2009, Dr. Olmstead, Chief Science Officer for ProThera®

and Klaire Labs™, gave a lecture to the Physicians’ Roundtable meeting in

Greenville, North Carolina on gastrointestinal biofilm. The presentation was

entitled:

Life on the Edge: The Clinical Implications of Gastrointestinal Biofilm. and can

be found here:

http://www.thefreelibrary.com/Life+on+the+edge:+the+clinical+implications+of+gas\

trointestinal+...-a0211561662

He talks a bit about CFS and I'll quote it below. (Marti if you think it's too

much just remove it and it can be read in the article listed above.)

[-start]

Chronic Fatigue Syndrome

Chronic fatigue syndrome (CFS) consists of debilitating fatigue often associated

with arthralgias, myalgias, chills, feverishness, and lymphadenopathy. (36) CFS

clinically overlaps with other illnesses such as fibromyalgia. (37) The normal

gastrointestinal microbiota are frequently disrupted in people with CFS and

fibromyalgia. These disorders are associated with a gut microflora low in

Bifidobacterium and high in Enterococcus species. (38) Higher enterococcal

counts correlate with more severe neurological and cognitive symptoms.

While its etiology is unknown, one long-standing, albeit controversial,

hypothesis is that chronic fatigue syndrome is caused by an immune response to

intestinal colonization by C. albicans. (39), (40) Increased fecal counts of C.

albicans have been described during the early phase of the syndrome. (41)

Treatment with antifungal agents, together with a special diet, has been

described as improving the symptomatology of patients with CFS. (42)

Improvements are often transient, and the role of C. albicans in CFS and related

disorders remains contentious, in part because there is no definite test and

yeast overgrowth as documented by fungal cultures is uncommon in these patients.

A refinement of the C. albicans hypothesis is that CFS symptoms are caused by an

immune response to Candida species residing within biofilm in the

gastrointestinal tract. Candida species ubiquitously form biofilm communities,

and most manifestations of candidiasis are associated with biofilm formation.

(17), (43) Genes coding for multidrug efflux pumps are upregulated in Candida

biofilms, contributing to treatment resistance. (17) The biofilm characteristics

of slow growth and presence of persister microorganisms would explain the

tendency for patients to relapse following a beneficial symptomatic response to

therapy. (44)

The combination of antifungals with agents designed to disrupt biofilm, along

with pre- and probiotics to reestablish balanced gastrointestinal microbiota,

may offer an innovative approach to treating patients with CFS, fibromyalgia,

and other chronic disorders associated with gastrointestinal dysbiosis and

Candida biofilms.

[-end]

I won't bore you too much with data, the cpnhelp.org web site is full with stuff

to discover so now over to me ;-)

I did not do my homework, I usually take nothing dr's tell me for granted and

when they leave I'll check everything and make up my mind on how to handle or

implement it.

This time the InterfasePlus sounded innocent. My dr. said take these enzymes for

about 3 - 4 weeks they help to brake open the biofilm, we will than start the

abx and kill them all. Sounded doable. I did not worry about the enzymes, I had

been taken very high doses of enzymes for 3 years, serrapeptase, nattokinase,

Wobenzym etc. I should have checked.

I ordered the InterfasePlus and out of precaution I broke open the caps and took

half on an empty stomach as directed. For an hour I felt fine and than it hit me

like a hammer. I started sweating, became very warm, shooting pains through my

right arm, and the dreadful arrhythmia. Chest pain like an elephant sitting on

my chest and I could not regulate my heartbeat. After some rest and acupressure

I started to feel reasonable again until stupid me took the second dose. Now I

was certain it was caused by the InterfasePlus. For 'just enzymes' they had

delivered a powerful punch.

Someone of the cpnhelp web site was so kind to direct me to the file mentioned

above and in that file Dr. Olmstead speaks of going slow and low. Start

with the regular Interfase and not with InterfasePlus. That is what you get if

you do not check your stuff.

Apparently the Cpn is most active in my heart and causes inflammation and

elevated CPR's and I have cardiomyopathy. The arrhythmia scare me so much, I'm

anxious that I will end up in a cardiac arrest if I'm not careful. But if I want

to see any improvement in my condition and not stay in bed until I vegetate and

die, I need to get a handle on this.

So it was back to the drawing board, ordered the Interfase caps without the Plus

and also ordered a product from WTSmeds called Cardiac Px. It helps in

regulating and help maintain cardiac rate and rhythm. There is also another

homeopathic product I liked but my dr. need to order that for me Pekana:

Cardinorma, Coro-calm.

I know I need to take some stuff to 'mop' up the toxins and waste. Activated

Charcoal probably although I have no idea when I should take it. Before sleep it

might interfere with my sleep meds?

Is there anything else that someone can recommend that will aid in this?

Thanks for reading all the way through ;-)

--

Portland, OR

* Klaire labs http://www.klaire.com/