Guest guest Posted February 11, 2010 Report Share Posted February 11, 2010 It affects the quality of the gene's passed on.... Marcia sagefox wrote: > Sorry everyone. My parents were 22. I feel that CFIDS absolutely must be related to Autism, as I had experience with a close friend with two sibs who had Autism and my cousin has Asperger's, and I always felt that this felt like " acquired autism. " I think the causes may be different though- at least they hit at different ages- and I don't think it has much to do with parents' ages. If CFIDS is caused by XMRV, why would a virus care how old the host's parents are? > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 11, 2010 Report Share Posted February 11, 2010 HI a According Rich's hypothesis If you have the genetic predisposition anything that depletes glutathione can trigger CFS That could be disease or environmental toxins or emotional trauma or a combination of theses I know many people that went through hell in their childlhood and they don't have CFS your Dad is a good example of that I also know people that had fairly healthy childhoods and they do have CFS in their case it was some other stressor or combination of stressors In my case the stressors were child abuse/ neglect poor nutrition and possibly sickness early on So for me it was the combination of bad genetics and other stressors Now there is a possibility that my stressors caused other reactions in my body and that lead to CFS But I have little doubt that for me those early events contributed to my sickness Steve On Feb 11, 2010, at 7:29 PM, paula wrote: > Hi Steve, > We don't know what causes cfs yet. I think we are getting close. But > one thing that doesn't cause it is childhood trauma. My dad lived to > age 96, healthy as a horse into his old age. His father was an > abusive alcoholic who tried to kill him with a shotgun when he was > about ten. The disease, whatever it is, has to be there before the > trauma can trigger it. I am sure you get this, but I just couldn't > keep from writing it once again. > > a Carnes > > > > > Hi > > > > My Father was 38 and my Mother was 27 when I was born > > While that may have predisposed me it was childhood trauma neglect > and > > or sickness that triggered it for me > > > > It has been a lifelong illness > > > > Thanks > > > > Steve > > > " Great spirits have always found violent opposition from mediocrities. The latter cannot understand it when a man does not thoughtlessly submit to hereditary prejudices but honestly and courageously uses his intelligence. " Albert Einstein Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 12, 2010 Report Share Posted February 12, 2010 My parents were around 20,30 at my birth date but my mother had lived a stressful life and my father had adrenal problems.I was also partially breast fed. My grandmother from my fathers side had thyroid,allergy and kidney problems.I developed CFS after a traumatic event. I am thinking I had some genetic predisposition to this illness but not sure if it was due to inability to detoxify or hormonal problems or what. best wishes cindi Re: parents ages Hi a, If we don't know what causes it, how can we say " something " doesn't cause it. I think it is inappropriate to state that Steve didn't get CFS due to trauma. You cannot speak for him or his life based on your father's experience. Trauma, physical or emotional, does create imbalance in the cortisol response which is a possible trigger and may in fact cause the cascade that is know to begin the illness process. This harkens back to the terrain/trigger which is a very fruitless argument. It is most likely a combination of both. Marti > > Hi Steve, > We don't know what causes cfs yet. I think we are getting close. But one thing that doesn't cause it is childhood trauma. My dad lived to age 96, healthy as a horse into his old age. His father was an abusive alcoholic who tried to kill him with a shotgun when he was about ten. The disease, whatever it is, has to be there before the trauma can trigger it. I am sure you get this, but I just couldn't keep from writing it once again. > > a Carnes > > > > > Hi > > > > My Father was 38 and my Mother was 27 when I was born > > While that may have predisposed me it was childhood trauma neglect and > > or sickness that triggered it for me > > > > It has been a lifelong illness > > > > Thanks > > > > Steve > ------------------------------------ This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 12, 2010 Report Share Posted February 12, 2010 yes All that makes sense Far a survivor of early childhood trauma there is a two prong battle One is the deal with the emotional damage done Another is to address the physical damage It is almost a full time job steve On Feb 12, 2010, at 9:56 AM, whoopandado wrote: > FWIW: > > http://www.ncbi.nlm.nih.gov/pubmed/19124690? > > Arch Gen Psychiatry. 2009 Jan;66(1):72-80. > > Childhood trauma and risk for chronic fatigue syndrome: association > with neuroendocrine dysfunction. > > " Our results confirm childhood trauma as an important risk factor of > CFS. In addition, neuroendocrine dysfunction manifested by decreased > salivary cortisol awakening response was associated with childhood > trauma in CFS, likely reflecting a biological correlate of > vulnerability due to early developmental insults. The associations > observed in this study are particularly important because we > evaluated persons with CFS and well control subjects identified from > the Georgia population rather than clinical settings. Thus, the > results can be generalized to the population of persons with CFS. " > > And from their previous 2006 study: > > http://www.ncbi.nlm.nih.gov/pubmed/17088506? > > " stress early in life, during critical periods of heightened brain > plasticity, permanently affects brain regions involved in cognitive- > emotional processing and control of regulatory outflow systems (eg, > the endocrine, autonomic, and immune systems). Behavioral and > physiological effects of early stress in animal models are similar > to symptoms of CFS. For example, adverse rearing conditions in > nonhuman primates induce decreased basal cortisol secretion. Such > hypocortisolism has also been described for patients with CFS other > functional somatic syndromes, and PTSD. Low cortisol levels might > lead to disinhibition of immune mediators and central-autonomic > stress responses that in turn could evolve into fatigue, pain, > cognitive impairment, and emotional symptoms. Mild adrenal > dysfunction and increased circulating cytokines have been reported > for adult women with histories of childhood abuse. In sum, childhood > adversity appears to alter the same regulatory systems that convey > vulnerability to stress and that have been implicated in the > pathophysiology of CFS. " > > " However, early-life stress does not always lead to CFS, and > resiliency factors must be considered. It is likely that certain > dispositional factors, ie, genes and sex, moderate the relationship > between early-life stress and CFS, possibly by influencing the > brain's response to stress. " > > > " Great spirits have always found violent opposition from mediocrities. The latter cannot understand it when a man does not thoughtlessly submit to hereditary prejudices but honestly and courageously uses his intelligence. " Albert Einstein Quote Link to comment Share on other sites More sharing options...
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