Guest guest Posted January 24, 2000 Report Share Posted January 24, 2000 Bren, LEF has an article about carnitine at this URL: http://www.lef.org/prod_desc/item00051.html Personally I doubt that it is very useful for weight loss, at least in comparison to other things. I lost a ton of weight in a very short time period of about five months merely by restricting carbohydrates. I never went hungry and I never counted calories. I ate lots of meat including the fat, and eggs and cheese and some vegetables. I eliminated bread and milk and potatoes and cereal and sugar, and reduced fruit to one piece per day. My weight dropped dramatically. I went from about 225 to about 170. I then eliminated cheese and dropped as low as 160, which is too low for me. Now I am eating a lot of sweet fruits and vegetables and trying very hard to put weight back on without indulging in hi-glycemic and starchy foods. I really would like to gain about 10 lbs but I'm finding it very difficult to gain weight without recourse to unhealthy crap like white bread and candy and ice cream. It's a nice problem to have! -gts Carnitine > I read an article about carnitine and its benefits for health and weight > control. Could someone tell me about its benefits in a weight loss > program. As part of my longevity plan, I need to lose 20 pounds. > Bren > > ------------------------------------------------------------------------ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2000 Report Share Posted January 24, 2000 Bren Below is a link to Life Extension Foundation magazine's book review of the book 'The Carnitine Miracle' by Crayhon. It is quiet long and has a lot of info but i'd recommend picking up a copy at any book store or order it over the internet. Also a search of past LEF magazines turned up 40 pages with info about carnitine and its health benefits. http://www.lef.org/prod_desc/item33390.html Good luck Sisson > I read an article about carnitine and its benefits for health and weight > control. Could someone tell me about its benefits in a weight loss > program. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2000 Report Share Posted January 24, 2000 gts, Probably no one is going to feel sorry for you for not being able to gain weight. The majority of us would like to be in your shoes and we're going " cry me a river " . lol Jan >Bren, > >LEF has an article about carnitine at this URL: >http://www.lef.org/prod_desc/item00051.html > >Personally I doubt that it is very useful for weight loss, at least in >comparison to other things. > >I lost a ton of weight in a very short time period of about five months >merely by restricting carbohydrates. I never went hungry and I never counted >calories. I ate lots of meat including the fat, and eggs and cheese and some >vegetables. I eliminated bread and milk and potatoes and cereal and sugar, >and reduced fruit to one piece per day. My weight dropped dramatically. I >went from about 225 to about 170. I then eliminated cheese and dropped as >low as 160, which is too low for me. Now I am eating a lot of sweet fruits >and vegetables and trying very hard to put weight back on without indulging >in hi-glycemic and starchy foods. > >I really would like to gain about 10 lbs but I'm finding it very difficult >to gain weight without recourse to unhealthy crap like white bread and candy >and ice cream. It's a nice problem to have! > >-gts > > Carnitine > > >> I read an article about carnitine and its benefits for health and weight >> control. Could someone tell me about its benefits in a weight loss >> program. As part of my longevity plan, I need to lose 20 pounds. >> Bren >> >> ------------------------------------------------------------------------ >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 25, 2000 Report Share Posted January 25, 2000 I would like to advocate a diet that has a safer balance of nutrients. I tell my patients to follow a " mediterrean " diet. Still 40% protein, 30% fat, and 30% carb. Protein, vegetable is best, then fish, all other seafood, game, white meat foul, other foul, pork, and beef (in descending order or preferrence). Fats need to be " healthy " fats. Fish oil, flax seed oil, and borage oil are rich in essential fats. Olive oil is rich in mono unsaturated fat, along with other anti-oxidants. In descending order, the rest of the fats; vegetable oil, animal (other than fish) fat, and trans-fats (hydrogenated vegetable oils (avoid these as much as possible). Carbs need to be of the complex variety. NO sugar! Anything that is easily converted to sugar should also be limited (high glycemic index), simple starches such as pasta, bread, white rice, and potatoes are high in these. Legumes are an excellent source of protein and complex carbs. All dark green vegetables are good for you. You can have fruits and high glycemic vegetables (carrots and corn) just watch the quanity. Obviously I could wirte a book on this if I had the time, but these are the basics. Live long and well, and keep on learning. R , MD Medical Director, Hilton Head Longevity Center Medical Director, Physician's Longevity Products Inc Director R & D, The Anti-Aging Institute www.anti-agingcenter.com 888-412-4452 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 25, 2000 Report Share Posted January 25, 2000 Hi Gordon, Since you brought up the subject of high protein low carb--which I know works for weight loss, I have a hard time believing that this diet (especially the "don't worry about the fat" part) can be good for ones long term or maybe even short term health. My wife has just started on the Atkins diet to lose a few pounds and I am concerned about what she is not getting in the way of nutrients, although she is taking supplements. I love veggies and fruit, and really feel there is great nutritional value in them (esp raw). I can see the benefits of cutting down on carbs and especially processed foods and sugar of any kinds, but not veggies and fruit. I feel that one could still lose weight, maybe over a longer period of time, without going to the extreme of eliminating so many healthy foods and without putting such a load on the kidneys. We are always in such a hurry to get the job done, and with rapid weight loss being soooo appealing it might cause people to ignore more prudent action. I can already hear your answer, but I thought I would throw that out. Also what do you think this does for IGF-1 and overall energy levels. Thanks and I will pass your post on to her. Dale gts wrote: Bren, LEF has an article about carnitine at this URL: http://www.lef.org/prod_desc/item00051.html Personally I doubt that it is very useful for weight loss, at least in comparison to other things. I lost a ton of weight in a very short time period of about five months merely by restricting carbohydrates. I never went hungry and I never counted calories. I ate lots of meat including the fat, and eggs and cheese and some vegetables. I eliminated bread and milk and potatoes and cereal and sugar, and reduced fruit to one piece per day. My weight dropped dramatically. I went from about 225 to about 170. I then eliminated cheese and dropped as low as 160, which is too low for me. Now I am eating a lot of sweet fruits and vegetables and trying very hard to put weight back on without indulging in hi-glycemic and starchy foods. I really would like to gain about 10 lbs but I'm finding it very difficult to gain weight without recourse to unhealthy crap like white bread and candy and ice cream. It's a nice problem to have! -gts Carnitine > I read an article about carnitine and its benefits for health and weight > control. Could someone tell me about its benefits in a weight loss > program. As part of my longevity plan, I need to lose 20 pounds. > Bren > > ------------------------------------------------------------------------ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 25, 2000 Report Share Posted January 25, 2000 Hi Dale and All, Here is a post from Greg W. that also addresses this idea. Dale, I totally agree with what you said. Gordon, I wish I had that weight gain problem of yours; have you tried weight lifting with all that carlorie loading? Tom From: Greg <gowatson@...>Hi All,Here is an interesting paper showing that GH not only drives lipolysis(Fatty Acid release from fat cells) but also puts our mitochondrias intoburn Fatty Acid mode.This basically means that GH controls the gateways moving energy fromfat cells into muscles to be burnt.From this it should be clear how important GH is to fat loss and musclemass increase.I have a concern that Glucagon driven Ketogenic diets and theirresulting high Fatty Acid Levels will inhibit natural and / or aminoboosted GH release.Comments??========================TITLE: Stimulation of mitochondrial fatty acid oxidation by growth hormone inhuman fibroblasts.AUTHORS:Leung KC; Ho KKAUTHOR AFFILIATION: Garvan Institute of Medical Research, St. 's Hospital, Sydney,New South Wales, Australia.SOURCE: J Clin Endocrinol Metab 1997 Dec;82(12):4208-13ABSTRACT: In vivo administration of GH induces lipolysis and lipid oxidation. However, it is not clear whether the stimulation of lipid oxidation is adirect effect of GH or is driven by increased substrate supply secondaryto lipolysis. An in vitro bioassay has been established for assessing beta-oxidationof fatty acids in mitochondria, based on the measurement of conversionof tritiated palmitic acid to 5H2O by fibroblasts in culture. We have modified this assay to investigate whether GH stimulates fattyacid oxidation. GH stimulated oxidation of palmitic acid maximally by26.7 +/- 2.5% (mean +/- SEM; P < 0.0001). The stimulation was biphasic, with the oxidation rate increasing withincreasing GH concentration to a peak response at 1.5 nmol/L anddeclining to a level not significantly different from controlthereafter. Insulin-like growth factor-I at concentrations of up to 250 nmol/L hadno significant effect on fatty acid oxidation. GH-binding protein attenuated the effect of GH. An anti-GH receptor (GHR) antibody (MAb263), which dimerizes thereceptor and induces GH-like biological actions, significantlystimulated fatty acid oxidation. Another anti- GHR antibody (MAb5), which prevents receptor dimerization,suppressed GH action. In summary, GH directly stimulated fatty acid oxidation, an action notmediated by insulin-like growth factor-I. Dimerization of GHRs was necessary for this effect. This bioassay is a practical tool for studying the regulatory effects ofGH on lipid oxidation.========================-- Good Health & Long Life, Greg , http://www.ozemail.com.au/~gowatson Re: Carnitine Hi Gordon, Since you brought up the subject of high protein low carb--which I know works for weight loss, I have a hard time believing that this diet (especially the "don't worry about the fat" part) can be good for ones long term or maybe even short term health. My wife has just started on the Atkins diet to lose a few pounds and I am concerned about what she is not getting in the way of nutrients, although she is taking supplements. I love veggies and fruit, and really feel there is great nutritional value in them (esp raw). I can see the benefits of cutting down on carbs and especially processed foods and sugar of any kinds, but not veggies and fruit. I feel that one could still lose weight, maybe over a longer period of time, without going to the extreme of eliminating so many healthy foods and without putting such a load on the kidneys. We are always in such a hurry to get the job done, and with rapid weight loss being soooo appealing it might cause people to ignore more prudent action. I can already hear your answer, but I thought I would throw that out. Also what do you think this does for IGF-1 and overall energy levels. Thanks and I will pass your post on to her. Dale gts wrote: Bren, LEF has an article about carnitine at this URL: http://www.lef.org/prod_desc/item00051.html Personally I doubt that it is very useful for weight loss, at least in comparison to other things. I lost a ton of weight in a very short time period of about five months merely by restricting carbohydrates. I never went hungry and I never counted calories. I ate lots of meat including the fat, and eggs and cheese and some vegetables. I eliminated bread and milk and potatoes and cereal and sugar, and reduced fruit to one piece per day. My weight dropped dramatically. I went from about 225 to about 170. I then eliminated cheese and dropped as low as 160, which is too low for me. Now I am eating a lot of sweet fruits and vegetables and trying very hard to put weight back on without indulging in hi-glycemic and starchy foods. I really would like to gain about 10 lbs but I'm finding it very difficult to gain weight without recourse to unhealthy crap like white bread and candy and ice cream. It's a nice problem to have! -gts Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 25, 2000 Report Share Posted January 25, 2000 THANK YOU DR. HUGHES!!!!!!!!! RITE-ON! Re: Carnitine > I would like to advocate a diet that has a safer balance of nutrients. I > tell my patients to follow a " mediterrean " diet. Still 40% protein, 30% fat, > and 30% carb. Protein, vegetable is best, then fish, all other seafood, > game, white meat foul, other foul, pork, and beef (in descending order or > preferrence). Fats need to be " healthy " fats. Fish oil, flax seed oil, and > borage oil are rich in essential fats. Olive oil is rich in mono unsaturated > fat, along with other anti-oxidants. In descending order, the rest of the > fats; vegetable oil, animal (other than fish) fat, and trans-fats > (hydrogenated vegetable oils (avoid these as much as possible). Carbs need > to be of the complex variety. NO sugar! Anything that is easily converted > to sugar should also be limited (high glycemic index), simple starches such > as pasta, bread, white rice, and potatoes are high in these. Legumes are an > excellent source of protein and complex carbs. All dark green vegetables are > good for you. You can have fruits and high glycemic vegetables (carrots and > corn) just watch the quanity. Obviously I could wirte a book on this if I > had the time, but these are the basics. > > Live long and well, and keep on learning. > > R , MD > Medical Director, Hilton Head Longevity Center > Medical Director, Physician's Longevity Products Inc > Director R & D, The Anti-Aging Institute > www.anti-agingcenter.com > 888-412-4452 > > ------------------------------------------------------------------------ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 25, 2000 Report Share Posted January 25, 2000 Tom, this post from Greg is exactly what I was saying in a post here awhile back -- when I remarked that taking IGF-1 tests while in ketosis is probably not a good idea because fatty acids inhibit GH release. There is nothing wrong with being in ketosis while trying to lose weight, however. The body shifts into fat burning mode (ketosis) when carbohydrates (sugar) is in short supply. -gts Re: Carnitine Hi Gordon, Since you brought up the subject of high protein low carb--which I know works for weight loss, I have a hard time believing that this diet (especially the " don't worry about the fat " part) can be good for ones long term or maybe even short term health. My wife has just started on the Atkins diet to lose a few pounds and I am concerned about what she is not getting in the way of nutrients, although she is taking supplements. I love veggies and fruit, and really feel there is great nutritional value in them (esp raw). I can see the benefits of cutting down on carbs and especially processed foods and sugar of any kinds, but not veggies and fruit. I feel that one could still lose weight, maybe over a longer period of time, without going to the extreme of eliminating so many healthy foods and without putting such a load on the kidneys. We are always in such a hurry to get the job done, and with rapid weight loss being soooo appealing it might cause people to ignore more prudent action. I can already hear your answer, but I thought I would throw that out. Also what do you think this does for IGF-1 and overall energy levels. Thanks and I will pass your post on to her. Dale gts wrote: Bren, LEF has an article about carnitine at this URL: http://www.lef.org/prod_desc/item00051.html Personally I doubt that it is very useful for weight loss, at least in comparison to other things. I lost a ton of weight in a very short time period of about five months merely by restricting carbohydrates. I never went hungry and I never counted calories. I ate lots of meat including the fat, and eggs and cheese and some vegetables. I eliminated bread and milk and potatoes and cereal and sugar, and reduced fruit to one piece per day. My weight dropped dramatically. I went from about 225 to about 170. I then eliminated cheese and dropped as low as 160, which is too low for me. Now I am eating a lot of sweet fruits and vegetables and trying very hard to put weight back on without indulging in hi-glycemic and starchy foods. I really would like to gain about 10 lbs but I'm finding it very difficult to gain weight without recourse to unhealthy crap like white bread and candy and ice cream. It's a nice problem to have! -gts ------------------------------------------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 26, 2000 Report Share Posted January 26, 2000 Dear Gordon, I thought ketosis was bad and that diabetics have severe trouble because of it. Something to do with free radicals perhaps? And ketone bodies? Could you clear this up for me? --Glenn gts wrote: Tom, this post from Greg is exactly what I was saying in a post here awhile back -- when I remarked that taking IGF-1 tests while in ketosis is probably not a good idea because fatty acids inhibit GH release. There is nothing wrong with being in ketosis while trying to lose weight, however. The body shifts into fat burning mode (ketosis) when carbohydrates (sugar) is in short supply. -gts Re: Carnitine Hi Gordon, Since you brought up the subject of high protein low carb--which I know works for weight loss, I have a hard time believing that this diet (especially the "don't worry about the fat" part) can be good for ones long term or maybe even short term health. My wife has just started on the Atkins diet to lose a few pounds and I am concerned about what she is not getting in the way of nutrients, although she is taking supplements. I love veggies and fruit, and really feel there is great nutritional value in them (esp raw). I can see the benefits of cutting down on carbs and especially processed foods and sugar of any kinds, but not veggies and fruit. I feel that one could still lose weight, maybe over a longer period of time, without going to the extreme of eliminating so many healthy foods and without putting such a load on the kidneys. We are always in such a hurry to get the job done, and with rapid weight loss being soooo appealing it might cause people to ignore more prudent action. I can already hear your answer, but I thought I would throw that out. Also what do you think this does for IGF-1 and overall energy levels. Thanks and I will pass your post on to her. Dale gts wrote: Bren, LEF has an article about carnitine at this URL: http://www.lef.org/prod_desc/item00051.html Personally I doubt that it is very useful for weight loss, at least in comparison to other things. I lost a ton of weight in a very short time period of about five months merely by restricting carbohydrates. I never went hungry and I never counted calories. I ate lots of meat including the fat, and eggs and cheese and some vegetables. I eliminated bread and milk and potatoes and cereal and sugar, and reduced fruit to one piece per day. My weight dropped dramatically. I went from about 225 to about 170. I then eliminated cheese and dropped as low as 160, which is too low for me. Now I am eating a lot of sweet fruits and vegetables and trying very hard to put weight back on without indulging in hi-glycemic and starchy foods. I really would like to gain about 10 lbs but I'm finding it very difficult to gain weight without recourse to unhealthy crap like white bread and candy and ice cream. It's a nice problem to have! -gts ------------------------------------------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 21, 2000 Report Share Posted August 21, 2000 I looked up some of my papers from the Pediatric Neurology Dept. of Children's Hospital Oakland, Ca to answer your question. Brook's neurologist has always prescribed Carnitor with Depakote. WHAT IS CARNITINE? Carnitine is a naturally occurring substance required for energy metabolism. Carnitine is produced by the body and is also available in the diet (particularly in red meat and cow's milk). WHY IS CARNITINE IMPORTANT? Without an adequate amount of Carnitine the utilization of fatty acids as an energy source for all tissues, particularly the heart and skeletal muscle tissue is impaired. Symptoms of Carnitine deficiency are muscle weakness, heart failure, low blood sugar, and possibly liver deficiency. Severe chronic Carnitine deficiency may be associated with lethargy, slow development, failure to thrive and frequent infections. WHAT CAUSES CARNITINE DEFICIENCY? Carnitine deficiency can occur when the diet lacks Carnitine or if conditions exist that cause abnormal loss or overutilization of Carnitine. Administration of Valporic Acid (Depakote or Depakene) has been associated with Carnitine deficiency, and often a supplement of Carnitine is necessary. This is the basic info, but I also have several articles on Carnitine deficiency associated with anticonvulsant therapy. Marisa Mom to Miles 13 Brook 10 and Gennie 3 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2008 Report Share Posted December 15, 2008 Okay, that is a lot of big phases below, but, I think I get it, and just wanted to say, I started a regime of adding Carnitine and Selenium to my daily diet, and truly finding more energy, after two years of endless fatigue, I am playing music and dancing again. last month I had a jump to 147000 viral load and drop to 350 tcells, from the flu, but, still, I started these new supplements and seem to be recovering to a level above when I had the flu. I would never have been able or interested in emailing back, but, that has changed. larryOn Dec 12, 2008, at 4:42 AM, wrote:...the other issue is that, as with many micronutrients, carnitine levels are often seen to decline in HIV disease. M. ** Ann N Y Acad Sci. 2004 Nov;1033:132-8.Click here to read Links Carnitines and its congeners: a metabolic pathway to the regulation of immune response and inflammation. Famularo G, De Simone C, Trinchieri V, Mosca L. Department of Internal Medicine, San Camillo Hospital, Circonvallazione Gianicolense, 00152 Rome, Italy. gfamularoscamilloforlanini (DOT) rm.it Carnitine and its congeners may regulate the immune networks, and their influence on functions of immune cells predominantly or exclusively relies on carnitine-dependent energy production from fatty acids. A reduced pool of carnitines has been demonstrated in either serum or tissues, or both, from patients with a wide spectrum of disorders characterized by unregulated or impaired immune responses ranging from sepsis syndrome to systemic sclerosis, infection with human immunodeficiency virus, and chronic fatigue syndrome. Furthermore, experimental studies have consistently reported that the deranged immune responses and the less efficient inflammation towards infectious organisms associated with aging may be enhanced or modulated by treatment with carnitines. There is also evidence that carnitine deprivation could adversely affect the course of the sepsis syndrome, at least in experimental models, and preliminary studies suggest that carnitine deficiency is ultimately implicated in the pathophysiology of endotoxin-mediated multiple organ failure. Several data indicate that carnitine deficiency is a contributing factor to the progression of infection with human immunodeficiency virus, and carnitine therapy in those patients could counteract the unregulated process of lymphocyte apoptosis and improve CD4 counts. Some case reports have suggested the use of carnitine for the treatment of the severe lactic acidosis that complicates in some patients the use of reverse transcriptase inhibitors. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2008 Report Share Posted December 15, 2008 I have the same experience with 2000 mg of Carnitine a day.  It gives me energy and my mind works better.  I have taken it for 18 years now.  My LDL and triglycerides have always been great, except for HDL, which is a struggle to bring it over 40 without getting lots of niacin flush.  SAMe plus Carnitine are amazing together for fatigue and mood.  Those of you suffering from "blue times" without energy and motivation should not only get your hormones checked, but give SAMe a try, specially with other supplements like Carnitine.  But there is little to no data to substantiate my personal anecdote, however. SAMe has kept me sane through 5 months of being in bed with back problems, for sure. AZT can decrease carnitine.  There is no data on other HIV medications. Hopefully we will learn more from this study (I wish I could join it) http://clinicaltrials.gov/ct2/show/NCT00386971?term=carnitine+HIV & rank=1 and this one http://clinicaltrials.gov/ct2/show/NCT00572429?term=carnitine+HIV & rank=2 Vergel powerusa.org Re: carnitine Okay, that is a lot of big phases below, but, I think I get it, and just wanted to say, I started a regime of adding Carnitine and Selenium to my daily diet, and truly finding more energy, after two years of endless fatigue, I am playing music and dancing again.  last month I had a jump to 147000 viral load and drop to 350 tcells, from the flu, but, still, I started these new supplements and seem to be recovering to a level above when I had the flu.  I would never have been able or interested in emailing back, but, that has changed.  larry On Dec 12, 2008, at 4:42 AM, wrote: ....the other issue is that, as with many micronutrients, carnitine levels are often seen to decline in HIV disease. Ge orge M. **  Ann N Y Acad Sci. 2004 Nov;1033:132-8.Click here to read Links    Carnitines and its congeners: a metabolic pathway to the regulation of immune response and inflammation.    Famularo G, De Simone C, Trinchieri V, Mosca L.    Department of Internal Medicine, San Camillo Hospital, Circonvallazione Gianicolense, 00152 Rome, Italy. gfamularo@s camilloforlanini.rm.it    Carnitine and its congeners may regulate the immune networks, and their influence on functions of immune cells predominantly or exclusively relies on carnitine-dependent energy production from fatty acids. A reduced pool of carnitines has been demonstrated in either serum or tissues, or both, from patients with a wide spectrum of disorders characterized by unregulated or impaired immune responses ranging from sepsis syndrome to systemic sclerosis, infection with human immunodeficiency virus, and chronic fatigue syndrome. Furthermore, experimental studies have consistently reported that the deranged immune responses and the less efficient inflammation towards infectious organisms associated with aging may be enhanced or modulated by treatment with carnitines. There is also evidence that carnitine deprivation could adversely affect the course o f the sepsis syndrome, at least in experimental models, and preliminary studies suggest that carnitine deficiency is ultimately implicated in the pathophysiology of endotoxin-mediated multiple organ failure. Several data indicate that carnitine deficiency is a contributing factor to the progression of infection with human immunodeficiency virus, and carnitine therapy in those patients could counteract the unregulated process of lymphocyte apoptosis and i mprove CD4 counts. Some case reports have suggested the use of carnitine for the treatment of the severe lactic acidosis that complicates in some patients the use of reverse transcriptase inhibitors. Listen to 350+ music, sports, news radio stations including songs for the holidays FREE while you browse. Start Listening Now! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2008 Report Share Posted December 15, 2008 As for my HIV doctor intructions, he never lets me do a blood test after a cold or a flufor a least 2 weeks  for that very reason, you are not going to get real numbers.That said I have been surprised few times in the past when people on this list with neurophaty were not on Carnitor, their doctors did not know that the first thing to do with neurophaty is to check Carnitine levelswith a simple blood test, taken in time Carnitine can reverse neurophaty or as in my case allows me to take my medications with out worsening my neurophaty condition (from prior medications).I wish I had know about Carnitine few years ago when I got neurophaty for the first time, sigh!From: livingthelava <livingthelava@...> <fiar@...>Cc: < >Sent: Monday, December 15, 2008 6:23:31 PMSubject: Re: carnitine Okay, that is a lot of big phases below, but, I think I get it, and just wanted to say, I started a regime of adding Carnitine and Selenium to my daily diet, and truly finding more energy, after two years of endless fatigue, I am playing music and dancing again.  last month I had a jump to 147000 viral load and drop to 350 tcells, from the flu, but, still, I started these new supplements and seem to be recovering to a level above when I had the flu.  I would never have been able or interested in emailing back, but, that has changed.  larryOn Dec 12, 2008, at 4:42 AM, wrote:...the other issue is that, as with many micronutrients, carnitine levels are often seen to decline in HIV disease. M. ** Ann N Y Acad Sci. 2004 Nov;1033:132- 8.Click here to read Links   Carnitines and its congeners: a metabolic pathway to the regulation of immune response and inflammation.   Famularo G, De Simone C, Trinchieri V, Mosca L.   Department of Internal Medicine, San Camillo Hospital, Circonvallazione Gianicolense, 00152 Rome, Italy. gfamularo@scamillof orlanini. rm.it   Carnitine and its congeners may regulate the immune networks, and their influence on functions of immune cells predominantly or exclusively relies on carnitine-dependent energy production from fatty acids. A reduced pool of carnitines has been demonstrated in either serum or tissues, or both, from patients with a wide spectrum of disorders characterized by unregulated or impaired immune responses ranging from sepsis syndrome to systemic sclerosis, infection with human immunodeficiency virus, and chronic fatigue syndrome. Furthermore, experimental studies have consistently reported that the deranged immune responses and the less efficient inflammation towards infectious organisms associated with aging may be enhanced or modulated by treatment with carnitines. There is also evidence that carnitine deprivation could adversely affect the course of the sepsis syndrome, at least in experimental models, and preliminary studies suggest that carnitine deficiency is ultimately implicated in the pathophysiology of endotoxin-mediated multiple organ failure. Several data indicate that carnitine deficiency is a contributing factor to the progression of infection with human immunodeficiency virus, and carnitine therapy in those patients could counteract the unregulated process of lymphocyte apoptosis and improve CD4 counts. Some case reports have suggested the use of carnitine for the treatment of the severe lactic acidosis that complicates in some patients the use of reverse transcriptase inhibitors. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 16, 2008 Report Share Posted December 16, 2008 "I have the same experience with 2000 mg of Carnitine a day. Â It gives me energy and my mind works better. Â I have taken it for 18 years now. "Some of the things we have talked about for mitochondrial toxicity may be helpful with fatigue. I have been in on discussions of trials for Coenzyme Q and creatine. They could be worth a shot.JB Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 22, 2009 Report Share Posted November 22, 2009 Does anyone supplement with Carnitine? My levels were low on Metametrix test. Thank you! -- Margaret www.margaretburns.net/blog www.wpinstitute.org Quote Link to comment Share on other sites More sharing options...
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