Yet another vaccine for a disease caused by vaccines

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Crohn's disease vaccine breakthrough announced

KURT BAYER

SCIENTISTS have successfully tested a vaccine against Crohn's disease,

the debilitating digestive illness.

Scotland has the world's worst rates of the crippling condition, and the

number of Scots under 30 with Crohn's has tripled in 20 years.

Britain's leading expert on Crohn's disease has long blamed a six-fold

increase in the condition since the 1950s on milk products and

contaminated water.

Now Hermon-, professor of surgery at St 's Hospital in

London, believes he has made the breakthrough that could spell the end

of the incapacitating disease.

Prof Hermon- has conducted pre-clinical vaccine tests on mice and

says preliminary results returned no signs of side-effects or adverse

reactions.

He said: " The vaccine proved highly successful in both treatment and

prevention in pre-clinical trials.

" It was statistically highly significant both as an attenuation of

pre-existing infection and protection against subsequent infection. Such

a double-dip effect would be very, very useful in humans. "

Crohn's is a severe inflammation of the small intestine and the colon

that can require surgery. It is caused by the bug MAP (Mycobacterium

avium subspecies paratuberculosis), which is widely carried and

contracted by farm animals.

Prof Hermon- discovered MAP is being transmitted to humans in milk

products and from exposure to environmental sources, such as

contaminated water.

He and his team are now staging a fundraising drive to take the vaccine

to clinical trials.

This article: http://news.scotsman.com/health.cfm?id=1695232006