200 IU of Vitamin D3 can cause major change

[Guest guest]

I respectfully disagree, I've seen first hand 100 IU provoke a rise of

body temperature of 4 degrees for two hours in one individual that was

deficient (by lab results), and that pattern repeated for several weeks

and then lessened. In this case, it was actually Calcium and Vitamin D.

I have also read similar results reported by other people.

Mark, the human body rarely behaves along a straight linear line but

through state changes or thresholds (Markovian process). If you are

critically deficient, a small amount may provoke a state change that

would never been seen with people that are not as deficient. The intake

of vitamin D3 may not impact long term circulating levels, however it

may cause a ***short term*** spike which can trigger the body's systems

to kick off for a short term -- like the 4 degree rise in body

temperature.

Over long term, the circulating levels increased, and with it the

typical sub-normal temperatures seen in CFIDS moved towards the normal

(with an decrease of temperature intolerance).

To me, the poster's need to have food with it means that there is a

need to moderate this peak (despite being a low dosage) so that the

amount of immune system 'kickoff' is tolerable seem very appropriate.

IMHO

>

> Vitamin D by itself has basically no effect on any receptor. Oral

> vitamin D must first be converted to 25(OH)D (mainly by the liver),

> and then is converted to 1,25(OH)2D (at various sites), at which

> point it can activate VDRs. One 400IU pill by itself is pretty much

> unlikely to significantly raise circulating 25(OH)D levels. So any

> effects from the supplement might more likely be due to to the some

> other ingredient in the pill.