Guest guest Posted September 10, 2007 Report Share Posted September 10, 2007 warning re: artemisinins (aka wormwood) _______ Are currently deployed artemisinins neurotoxic? Toovey, 2006 Toxicology Letters () 166(2): 95-104 In vitro, animal, and human clinical studies suggest currently deployed artemisinins possess neurotoxic potential. A specific and consistent pattern of brainstem injuries that includes auditory processing centers has been reported from all laboratory animals studied. Hearing loss, ataxia, and tremor are reported from humans. Neurotoxicity appears mediated in part through artemisinin induced oxidative stress in exposed brainstems. In vitro studies suggest that artemisinin neurotoxicity does not manifest immediately upon exposure, but that once commenced it is inevitable and irreversible; extrapolation from in vitro data suggests that 14 days may possibly be required for full development, casting doubt upon some animal safety studies and human necropsy studies. Uncertainty remains over the neurotoxicity of currently deployed artemisinins, and their safety profile should be reviewed, especially in pediatric use. The development of non-neurotoxic artemisinins is possible and should be encouraged. © 2006 Elsevier Ireland Ltd. All rights reserved. above info found at http://trophort.com/011/776/011776864.html Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2007 Report Share Posted September 12, 2007 There's a surprise I have been taking wormwood in dried herb form for the last 12years i.e. 3/4 of a teaspoon which lasts 2days. I have found this really good for the gut. Wormwood has been found to benefit patients who suffer from gut parasites and other related problems. Thank you for bringing this to my attention. I will have to look into it further to find what amounts of wormwood are damaging e.g extract of wormwood and other type supplements under modern day production methods could mean that patients could much more easily overdose without knowing it. It would be useful to get some more background information on the tests made on humans and animals. Wormwood of course has been used for thousands of years but it would be useful to know what damage this could cause over a period of time and of course what amounts would be needed to cause this damage. Thanks again. Regards.Adam warning re: artemisinins (aka wormwood) warning re: artemisinins (aka wormwood) _______ Are currently deployed artemisinins neurotoxic? Toovey, 2006 Toxicology Letters () 166(2): 95-104 In vitro, animal, and human clinical studies suggest currently deployed artemisinins possess neurotoxic potential. A specific and consistent pattern of brainstem injuries that includes auditory processing centers has been reported from all laboratory animals studied. Hearing loss, ataxia, and tremor are reported from humans. Neurotoxicity appears mediated in part through artemisinin induced oxidative stress in exposed brainstems. In vitro studies suggest that artemisinin neurotoxicity does not manifest immediately upon exposure, but that once commenced it is inevitable and irreversible; extrapolation from in vitro data suggests that 14 days may possibly be required for full development, casting doubt upon some animal safety studies and human necropsy studies. Uncertainty remains over the neurotoxicity of currently deployed artemisinins, and their safety profile should be reviewed, especially in pediatric use. The development of non-neurotoxic artemisinins is possible and should be encouraged. © 2006 Elsevier Ireland Ltd. All rights reserved. above info found at http://trophort.com/011/776/011776864.html Quote Link to comment Share on other sites More sharing options...
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