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warning re: artemisinins (aka wormwood)

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warning re: artemisinins (aka wormwood)

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Are currently deployed artemisinins neurotoxic?

Toovey, 2006

Toxicology Letters () 166(2): 95-104

In vitro, animal, and human clinical studies suggest currently

deployed artemisinins possess neurotoxic potential. A specific and

consistent pattern of brainstem injuries that includes auditory

processing centers has been reported from all laboratory animals

studied. Hearing loss, ataxia, and tremor are reported from humans.

Neurotoxicity appears mediated in part through artemisinin induced

oxidative stress in exposed brainstems. In vitro studies suggest that

artemisinin neurotoxicity does not manifest immediately upon

exposure, but that once commenced it is inevitable and irreversible;

extrapolation from in vitro data suggests that 14 days may possibly

be required for full development, casting doubt upon some animal

safety studies and human necropsy studies. Uncertainty remains over

the neurotoxicity of currently deployed artemisinins, and their

safety profile should be reviewed, especially in pediatric use. The

development of non-neurotoxic artemisinins is possible and should be

encouraged. © 2006 Elsevier Ireland Ltd. All rights reserved.

above info found at

http://trophort.com/011/776/011776864.html

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There's a surprise I have been taking wormwood in dried herb form for the last

12years i.e. 3/4 of a teaspoon which lasts 2days. I have found this really good

for the gut. Wormwood has been found to benefit patients who suffer from gut

parasites and other related problems.

Thank you for bringing this to my attention.

I will have to look into it further to find what amounts of wormwood are

damaging e.g extract of wormwood and other type supplements under modern day

production methods could mean that patients could much more easily overdose

without knowing it.

It would be useful to get some more background information on the tests made on

humans and animals.

Wormwood of course has been used for thousands of years but it would be useful

to know what damage this could cause over a period of time and of course what

amounts would be needed to cause this damage. Thanks again. Regards.Adam

warning re: artemisinins (aka wormwood)

warning re: artemisinins (aka wormwood)

_______

Are currently deployed artemisinins neurotoxic?

Toovey, 2006

Toxicology Letters () 166(2): 95-104

In vitro, animal, and human clinical studies suggest currently

deployed artemisinins possess neurotoxic potential. A specific and

consistent pattern of brainstem injuries that includes auditory

processing centers has been reported from all laboratory animals

studied. Hearing loss, ataxia, and tremor are reported from humans.

Neurotoxicity appears mediated in part through artemisinin induced

oxidative stress in exposed brainstems. In vitro studies suggest that

artemisinin neurotoxicity does not manifest immediately upon

exposure, but that once commenced it is inevitable and irreversible;

extrapolation from in vitro data suggests that 14 days may possibly

be required for full development, casting doubt upon some animal

safety studies and human necropsy studies. Uncertainty remains over

the neurotoxicity of currently deployed artemisinins, and their

safety profile should be reviewed, especially in pediatric use. The

development of non-neurotoxic artemisinins is possible and should be

encouraged. © 2006 Elsevier Ireland Ltd. All rights reserved.

above info found at

http://trophort.com/011/776/011776864.html

Link to comment
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