Guest guest Posted January 2, 2007 Report Share Posted January 2, 2007 Hi, all. I know most PWCs are women while I'm not of course, but am currently wondering if low estradiol status as I've tested for might be an important common nexus or connection between male autistic kids, adult female PWCs and adult male PWCs? In looking at some pubmed literature and a basic description of estradiol's function in the brain, it seems those who become low in it might have or be more susceptible to cognitive problems as happens in autism and CFS. http://en.wikipedia.org/wiki/Estradiol Estradiol is the most important of the estrogens and it actually has testosterone as an important precursor to our bodies making it whether male or female. This is interesting in that autism has for a while now been suspected of being testosterone mediated and neurodegenerative, but since testosterone in normal healthy individuals becomes estradiol in the brain why isn't estradiol status or lack of it also a central focus in what might be causing autism and CFS? What if the mechanism for transforming testosterone to estradiol starts off or later becomes faulty, inhibited or not so robust for autistics and PWCs? Your comments are welcomed. Quote Link to comment Share on other sites More sharing options...
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