Re: Estradiol levels in CFS and Autism?

[Guest guest]

In a message dated 02/01/2007 22:36:25 GMT Standard Time,

david-hall@... writes:

Hi, all.

I know most PWCs are women while I'm not of course, but am currently

wondering if low

estradiol status as I've tested for might be an important common nexus or

connection

between male autistic kids, adult female PWCs and adult male PWCs? In

looking at some

pubmed literature and a basic description of estradiol's function in the

brain, it seems

those who become low in it might have or be more susceptible to cognitive

problems as

happens in autism and CFS.

_http://en.wikipediahttp://en.http://en_

(http://en.wikipedia.org/wiki/Estradiol)

Estradiol is the most important of the estrogens and it actually has

testosterone as an

important precursor to our bodies making it whether male or female. This is

interesting in

that autism has for a while now been suspected of being testosterone

mediated and

neurodegenerative, but since testosterone in normal healthy individuals

becomes estradiol

in the brain why isn't estradiol status or lack of it also a central focus

in what might be

causing autism and CFS?

What if the mechanism for transforming testosterone to estradiol starts off

or later

becomes faulty, inhibited or not so robust for autistics and PWCs?

Your comments are welcomed.

********The inability to hold onto fat may be why estradiol levels are so

low.

Estradiol is made via aromatse enzymein fatty tissue.

Regards

Cs

[Guest guest]

I wonder whether this has any bearing.

I am Female have CFS (20yrs - well diagnosed) , severe

PMS, and high testosterone. I wonder if theer is

something missing is the testosterone - estradiol

pathway? I can not tolerate any form of the pill/mini

pill, I always get worse bloating and additional

jaundice. CFS literate doc never been able to work it

out.

Jill

--- bhammanuk@... wrote:

>

> In a message dated 02/01/2007 22:36:25 GMT Standard

> Time,

> david-hall@... writes:

>

>

>

>

> Hi, all.

>

> I know most PWCs are women while I'm not of course,

> but am currently

> wondering if low

> estradiol status as I've tested for might be an

> important common nexus or

> connection

> between male autistic kids, adult female PWCs and

> adult male PWCs? In

> looking at some

> pubmed literature and a basic description of

> estradiol's function in the

> brain, it seems

> those who become low in it might have or be more

> susceptible to cognitive

> problems as

> happens in autism and CFS.

>

> _http://en.wikipediahttp://en.http://en_

> (http://en.wikipedia.org/wiki/Estradiol)

>

> Estradiol is the most important of the estrogens

> and it actually has

> testosterone as an

> important precursor to our bodies making it whether

> male or female. This is

> interesting in

> that autism has for a while now been suspected of

> being testosterone

> mediated and

> neurodegenerative, but since testosterone in normal

> healthy individuals

> becomes estradiol

> in the brain why isn't estradiol status or lack of

> it also a central focus

> in what might be

> causing autism and CFS?

>

> What if the mechanism for transforming testosterone

> to estradiol starts off

> or later

> becomes faulty, inhibited or not so robust for

> autistics and PWCs?

>

> Your comments are welcomed.

>

>

>

>

>

>

>

> ********The inability to hold onto fat may be why

> estradiol levels are so

> low.

> Estradiol is made via aromatse enzymein fatty

> tissue.

>

> Regards

> Cs

>

>

> [Non-text portions of this message have been

> removed]

>

>

__________________________________________________

[Guest guest]

Hi, Jill.

Severe symptoms of PMS could correlated to lowered gluathione levels as has been

hypothesized may be happening in woman with CFS. And high testosterone could

reflect

lowered estradiol in a woman(Have you had your estradiol levels checked?).

Estradiol is made by testostorone being aromatized. So, for some reason you may

have

suppression of aromatase or just don't make a healthy enough level of aromatase

to

produce the estradiol you need to have good brain function.

jilldiprose@...> wrote:

>

> I wonder whether this has any bearing.

> I am Female have CFS (20yrs - well diagnosed) , severe

> PMS, and high testosterone. I wonder if theer is

> something missing is the testosterone - estradiol

> pathway? I can not tolerate any form of the pill/mini

> pill, I always get worse bloating and additional

> jaundice. CFS literate doc never been able to work it

> out.

> Jill

>

> --- bhammanuk@... wrote:

>

> > david-hall@... writes:

> > _http://en.wikipediahttp://en.http://en_

> > (http://en.wikipedia.org/wiki/Estradiol)

> >

> > Estradiol is the most important of the estrogens

> > and it actually has

> > testosterone as an

> > important precursor to our bodies making it whether

> > male or female. This is

> > interesting in

> > that autism has for a while now been suspected of

> > being testosterone

> > mediated and

> > neurodegenerative, but since testosterone in normal

> > healthy individuals

> > becomes estradiol

> > in the brain why isn't estradiol status or lack of

> > it also a central focus

> > in what might be

> > causing autism and CFS?

> >

> > What if the mechanism for transforming testosterone

> > to estradiol starts off

> > or later

> > becomes faulty, inhibited or not so robust for

> > autistics and PWCs?

> >

> > Your comments are welcomed.

> >

> >

> >

> >

> >

> >

> >

> > ********The inability to hold onto fat may be why

> > estradiol levels are so

> > low.

> > Estradiol is made via aromatse enzymein fatty

> > tissue.

> >

> > Regards

> > Cs

> >

> >

> > [Non-text portions of this message have been

> > removed]

> >

> >

>

>

> __________________________________________________

>

[Guest guest]

Many thanx for your thoughts . No I have not had

estradiol levels checked - like everything with CFS it

seems " other " things are too hard for the drs too.

I've come to realise that everything (incl PMS (mg,

cortisol, thyroid) probably comes back to

glutathione!! After watching Cheney- I thank god he

was given a new heart. I find it really interesting

that Cheney is now speaker at the after dinner talk at

the IACFS meeting and now also on the name change

committee. I have never consulted with him, but have

been at some american conferences and seen him cruise

in and out. The person I know best is Bell and I

think he respects still. Do you know any more.

Klimas came to NZ and was so good - really stood

up to some rhematalogists re: the graded exercise

bullshit. She was good fun.

Who is this guy??

best Jill

--- davidhall2020 <david-hall@...> wrote:

> Hi, Jill.

>

>

>

> Severe symptoms of PMS could correlated to lowered

> gluathione levels as has been

> hypothesized may be happening in woman with CFS.

> And high testosterone could reflect

> lowered estradiol in a woman(Have you had your

> estradiol levels checked?).

>

>

>

> Estradiol is made by testostorone being aromatized.

> So, for some reason you may have

> suppression of aromatase or just don't make a

> healthy enough level of aromatase to

> produce the estradiol you need to have good brain

> function.

>

>

>

>

>

>

>

> jilldiprose@...> wrote:

> >

> > I wonder whether this has any bearing.

> > I am Female have CFS (20yrs - well diagnosed) ,

> severe

> > PMS, and high testosterone. I wonder if theer is

> > something missing is the testosterone - estradiol

> > pathway? I can not tolerate any form of the

> pill/mini

> > pill, I always get worse bloating and additional

> > jaundice. CFS literate doc never been able to

> work it

> > out.

> > Jill

> >

> > --- bhammanuk@... wrote:

> >

>

> > > david-hall@... writes:

> > > _http://en.wikipediahttp://en.http://en_

> > > (http://en.wikipedia.org/wiki/Estradiol)

> > >

> > > Estradiol is the most important of the

> estrogens

> > > and it actually has

> > > testosterone as an

> > > important precursor to our bodies making it

> whether

> > > male or female. This is

> > > interesting in

> > > that autism has for a while now been suspected

> of

> > > being testosterone

> > > mediated and

> > > neurodegenerative, but since testosterone in

> normal

> > > healthy individuals

> > > becomes estradiol

> > > in the brain why isn't estradiol status or lack

> of

> > > it also a central focus

> > > in what might be

> > > causing autism and CFS?

> > >

> > > What if the mechanism for transforming

> testosterone

> > > to estradiol starts off

> > > or later

> > > becomes faulty, inhibited or not so robust for

> > > autistics and PWCs?

> > >

> > > Your comments are welcomed.

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > > ********The inability to hold onto fat may be

> why

> > > estradiol levels are so

> > > low.

> > > Estradiol is made via aromatse enzymein fatty

> > > tissue.

> > >

> > > Regards

> > > Cs

> > >

> > >

> > > [Non-text portions of this message have been

> > > removed]

> > >

> > >

> >

> >

> > __________________________________________________

> >

[Guest guest]

Hi, Jill.

<jilldiprose@...> wrote:

>

> Many thanx for your thoughts . No I have not had

> estradiol levels checked - like everything with CFS it

> seems " other " things are too hard for the drs too.

> I've come to realise that everything (incl PMS (mg,

> cortisol, thyroid) probably comes back to

> glutathione!!

***I can personally vouch for that glutathione levels directly impact

function of thyroid, cortisol and even hypothalamic function in terms

of antidiurectic hormone production that when low leads to diabetes

insipidus in PWCs.

After watching Cheney- I thank god he

> was given a new heart. I find it really interesting

> that Cheney is now speaker at the after dinner talk at

> the IACFS meeting and now also on the name change

> committee. I have never consulted with him, but have

> been at some american conferences and seen him cruise

> in and out. The person I know best is Bell and I

> think he respects still. Do you know any more.

***No, I think your take is correct. Both are respectable and respect

each other in terms of CFS.

> Klimas came to NZ and was so good - really stood

> up to some rhematalogists re: the graded exercise

> bullshit. She was good fun.

> Who is this guy??

***He is the PWC we put in charge of sending " warm fuzzies " , ie, the

PWC community public relations communications, to the

psychopathologizer-CBT/GET treatment cure proponents for ME/CFS!

<david-hall@...> wrote:

>

> > Hi, Jill.

> >

> >

> >

> > Severe symptoms of PMS could correlated to lowered

> > gluathione levels as has been

> > hypothesized may be happening in woman with CFS.

> > And high testosterone could reflect

> > lowered estradiol in a woman(Have you had your

> > estradiol levels checked?).

> >

> >

> >

> > Estradiol is made by testostorone being aromatized.

> > So, for some reason you may have

> > suppression of aromatase or just don't make a

> > healthy enough level of aromatase to

> > produce the estradiol you need to have good brain

> > function.

> >

> >

> >

> >

[Guest guest]

Jill Diprose wrote:

> Klimas came to NZ and was so good - really stood

> up to some rhematalogists re: the graded exercise

> bullshit. She was good fun.

> Who is this guy??

> best Jill

Hi Jill,

did anyone finally tell you who this guy is?

- guy

[Guest guest]

Is this still the belief, that more women than men have CFS? I thought

that was debunked as menopausal symptoms being mistaken as 'CFS'.

>

> > Klimas came to NZ and was so good - really stood

> > up to some rhematalogists re: the graded exercise

> > bullshit. She was good fun.

> > Who is this guy??

> > best Jill

>

>

> Hi Jill,

> did anyone finally tell you who this guy is?

> - guy

>