Acambis starts Clostridium vaccine trial

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http://www.sharecast.com/cgi-bin/sharecast/story.cgi?story_id=579571

Acambis starts Clostridium vaccine trial

Mon 28 Nov 2005

ACM - Acambis

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LONDON (SHARECAST) - Acambis moved ahead today after it said it has started

a Phase I clinical trial of its investigational vaccine against Clostridium

difficile in healthy elderly subjects.

This follows an initial Phase I safety and immunogenicity trial in healthy

young adults that began in July and is the next step in the group’s

clinical development plan for this vaccine candidate, it said.

Acambis is the only company with a vaccine against Clostridium difficile,

which is characterised by diarrhoea and colitis, in clinical development.

Chief scientific officer of Acambis Dr Monath said, “The emerging

hyper-toxigenic C. difficile strain has become a growing problem in

hospitals around the world.”

“We believe that a preventative vaccine could be a particularly effective

approach in the fight against CDAD (C. difficile-associated disease) and

are pleased to be progressing our vaccine candidate into clinical testing

in one of the main target populations.”

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Sheri Nakken, R.N., MA, Classical Homeopath

Vaccination Information & Choice Network, Nevada City CA & Wales UK

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