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RE : arginine: Re: Brain Ammonia

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Hi Tea,

This is great to hear. I'm so glad you have gotten relief. So, the difference is

to investigate things and know what needs to be taken with them.

( I did know about Lysine, but not regarding HHV6 patients specifically.)

My diagnosing CFIDS Dr. put as my official full blown onset date, the moment I

ended up at the ER with severe HHV flare-up, which was after taking a strong

Arginine product...so I'm really aware and cautious of the connection.

( I already had CFIDS...he just used that as a tangible event for the date for

paperwork).

In those days I was just casting for straws, trying multiple things, having no

idea what was wrong with me.

Was testing or other sources how you decided on the ratio between Lysine and

Arginine?

I thought of a few questions, if that's all right. Was the ammonia a result of

poor kidney function? WHat was the kidney disorder, and what were the symptoms

of the two?

By the way, things were moving so fast, I did not have a chance to tell you

welcome back, and that your previous posts were really super...allot of helpful

suggestions, from personal experience.

Thanks,

Katrina

> >

> > I have been interested in this topic for a while to. In summary L-Ornithine,

L-arginine, tryptophan and certain antibiotics that lower ammonia producing gut

bacteria (see below) it's a bit old there are probably newer articles

> >

> > Nelly

> >

> > Indian J Med Res. 1992 Oct;96:292-6. Related Articles, Links

> >

> >

> > Effect of three antibacterial drugs in lowering blood & stool ammonia

production in hepatic encephalopathy.

> >

> > T, K, Cherian AM, Kanakasabapathy.

> >

> > Department of Medicine, Christian Medical College, Vellore.

> >

> > Neomycin (700 mg/8 h), ampicillin (500/6 h) and metronidazole (400 mg/8 h),

were compared for their effect, on oral administration for 4 days, in reducing

blood ammonia in 27 patients with stable chronic liver disease. It was found

that there was 38.2, 38.5 and 8.7 m mol/litre mean reduction in blood ammonia in

the neomycin, ampicillin and metronidazole treated groups respectively. The

difference in blood ammonia was statistically significant for both neomycin (P =

0.01) and ampicillin (P = 0.03) but there was no significant change after

metronidazole treatment (P = 0.6). The total stool enzyme activity at optimum pH

was maximally reduced by ampicillin and minimally with metronidazole. The

reduction was noted to be 3.51 m mol/1 (P = 0.01), 3.87 m mol/1 (P = 0.08) and

2.8 m mol/1 (P = 0.02) of NH3/g dry weight of stool for neomycin, ampicillin and

metronidazole respectively. The main bacterial gut enzymes responsible for

ammonia production, urease and protease, were found to be very sensitive to

stool pH. At pH 6 their activity was around 20 per cent of what was found in

optimum pH of 7.4 and at pH 5 it is only about 8 per cent of optimum activity.

None of the three antibacterial agents changed the stool pH significantly. It

can be concluded that oral neomycin and ampicillin are superior to oral

metronidazole in lowering blood ammonia.

> >

> > PMID: 1459672 [PubMed - indexed for MEDLINE]

> > Brain Ammonia

> >

> >

> >

> > There are a number of causes of Ammonia in the Brain. There's Excessive

> > exercise, Liver disease, Hepatic Encephalopathy, Radiation exposure,

> > brain Infections, messed up Neurotransmitters, etc, etc,

> >

> > I thought these pages might interest listmembers.

> >

> > Katrina

> >

> > ----------

> >

> > http://www.google.com/search?hl=en & ie=ISO-8859-1 & q=Brain+ammonia

> >

> >

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