Re: High Copper - Pangborn/Baker

[Guest guest]

Hi,

Glutathione, cysteine, zinc, B6 and other biochemicals are needed for MT

synthesis. As a group people with CFS do not have excess copper levels, although

some individuals do. The relevance of copper to CFS is unclear.

Blake

High Copper - Pangborn/Baker

There was a recent post on high copper,

and it arising along with adrenal fatigue.

There is mention of high copper in the Pangborn/Baker

book on Autism.

I have had high copper for a long time, and

the most relevant explaination to me seems

to be the one Pangborn/Baker are putting forward,

i.e. the metallothionein MT-IV binds copper in the

intestinal muscosa, preventing excessive uptake.

This copper is eventually shed and excreted.

MT-IV also protects DPPIV from " attack " . In

other words, deficient MT-IV leaves DPPIV exposed

and vunerable. p.205

[And deficient DPPIV in the intestinal

mucosa leads to poor protein digestion, which

could lead to leaky gut/dysbiosis, which could

then eventually lead to immune dysregulation

and adrenal compromise. So, the adrenal compromise/

high copper burdens, could likely be the end point,

of MT-IV deficiency.]

This my speculation.

I do not see the causes for deficiency of MR-IV.

Perhaps someone else will fill this in? (Genes +

modern toxic burdens again?)

I wonder if Dr. Shoemaker's mold/MSH deficiency

could fit in here? (deficiency of MSH leading to

damage of mucosal tissues).

Best,

Zippy

22 years PWC

Cheney patient