Deth DVD; AWESOME

[Guest guest]

I have watched Deth's presentation twice and will need to view

certain parts of it several more times. It will be hard for me to

summarize. It was a far more complex presentation than others. He is

AWESOME. Rich I assume you know his work but I wish I could make a

copy of this particular DVD for you. There is nothing quite like

watching someone summarize their work with powerpoint etc.

He is *the* methylation guy. He believes methionine synthase, an

enzyme, is at the center of all the methylation issues and of course

in autism. He explains in great detail how this pathway works, how

when you have inflammation/oxidation, your body shifts the pathway to

make glutathione, which actually then deprives the methylation

pathway. How the body turns b12 into methylb12 and how that can be

blocked, especially by mercury. Even small amounts of mercury can

totally block the activity of methionine synthase, but that blockade

can be restored by administering methylb12. How MTHFR mutations do

seem elevated in subsets of autism and can render one even more

vulnerable. Stuff we know but the other researchers give you the tip

of the iceberg and he delves into the entire pathway(s) and how they

work, step by step.

Interestingly, very interestingly, dopamine is involved. I already

knew the research that extra repeats of the dopamine allele tended to

increase risk of ADHD etc. But anyway, methylation is necessary for

dopamine, and both dopamine and IGF1 can stimulate methylation. Proper

methylation actually keeps the phospholipid membrane fluid, and that

allows proper protein folding.

I found THAT particularly interesting and RICH I NEED YOUR THINKING

CAP here. Why? Because its very clear the lipopolysacharides on

borrelia as well as other bacteria, hijack and corrupt and screw up

the phospholipid membrane of the cell. And we know that

Kane's method of treating neurological disorders like Parkinson's (oh

yes, he talked about Parkinson's, gamma frequency oscillations of

nerves, and how meditators can instantly shift into gamma

oscillations, and how autistics are lower in this, and others who are

developmentally disabled also are...this seems related to dopamine

too...) anyway, her method is lipostabil and glutathione. She restores

the lipid membrane with IV phosopholipids. And so, I saw a connection

here. She is manually restoring the membrane, by giving the end

product of methylation required under high oxidative

stress/inflammation (glutathione), and the phospholipid that composes

60% of the cell membrane...but this is the first time I really saw the

connection, that proper methylation actually would allow the

phospholipid membrane to remain intact...

He also talked about other stuff that hasn't sunk in yet because as

far as I know, nobody else is talking about it. So I will watch it 2

more times tomorrow (the parts that my brain couldn't hold on to).

He is superb. I really hope I get a chance to talk to him. Also, his

presentation used simple illustrative tools...he must be a good

teacher, and he has no apparent ego at all. He has the demeanor of a

true scientist. Still, a lot of it has not entered my head yet enough

to stay there. Much of it was unfamiliar territory for me and not ever

discussed on this list.