Guest guest Posted July 26, 2006 Report Share Posted July 26, 2006 In teeny tiny doses, yes. You can't really know unless you try again. It certainly could've kicked your immune system into action against some infection and made you feel so bad. But no reason to do it so drastically. But really, Rich is the glutathione expert. Adrienne Crash on Glutathione then increased energy I wrote earlier about my attempt to take liposomal glutathione. I crashed harder than I have in a long time. For a couple of weeks I thought I had taken a major step backward. Here's the weird part: Now that I've recovered for a few days, I feel more energy than usual. I've been a lurker on this list for 7-8 years with few posts of my own because I usually don't have the energy to join in on the conversation. I have so much energ that this is probably my 5th post in two days. I'm typing like a mad woman. Does anybody think that it could be a longer term effect of the glutathione? I'm wondering if I should start taking it again? Lynn This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 26, 2006 Report Share Posted July 26, 2006 Question: Is trying new therapies and/or processes comparable to macrobiotics in that when switching over to a " good " , supportive behavior that it's possible you'll get sick in the short-term as you are either detoxing and/or the toxins are being pushed out of your body? Would that be a possible scenario of the below? I've been wondering this as I start to integrate some suggestion in to my life. And wondering if I need to prepare for some added " down time " ? Thanks, Laurel Re: Crash on Glutathione then increased energy In teeny tiny doses, yes. You can't really know unless you try again. It certainly could've kicked your immune system into action against some infection and made you feel so bad. But no reason to do it so drastically. But really, Rich is the glutathione expert. Adrienne Crash on Glutathione then increased energy I wrote earlier about my attempt to take liposomal glutathione. I crashed harder than I have in a long time. For a couple of weeks I thought I had taken a major step backward. Here's the weird part: Now that I've recovered for a few days, I feel more energy than usual. I've been a lurker on this list for 7-8 years with few posts of my own because I usually don't have the energy to join in on the conversation. I have so much energ that this is probably my 5th post in two days. I'm typing like a mad woman. Does anybody think that it could be a longer term effect of the glutathione? I'm wondering if I should start taking it again? Lynn This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 26, 2006 Report Share Posted July 26, 2006 On Jul 26, 2006, at 8:30 PM, tloyd61275 wrote: > I wrote earlier about my attempt to take liposomal glutathione. I > crashed harder than I have in a long time. For a couple of weeks I > thought I had taken a major step backward. > > Here's the weird part: Now that I've recovered for a few days, I feel > more energy than usual. I've been a lurker on this list for 7-8 years > with few posts of my own because I usually don't have the energy to > join in on the conversation. I have so much energ that this is > probably my 5th post in two days. I'm typing like a mad woman. > > Does anybody think that it could be a longer term effect of the > glutathione? I'm wondering if I should start taking it again? I had similar experiences when I went on lipo. You probably just took more than your body could handle. If you've been sick a long time, and have a high tox load to clear, it can be really awful when it all starts to come down. The fact that you feel significantly better now suggests that it was probably doing a good job of it, though. But you need to start a lot smaller, and work into it. Sara Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 26, 2006 Report Share Posted July 26, 2006 On Jul 26, 2006, at 9:35 PM, Laurel Ley wrote: > Question: Is trying new therapies and/or processes comparable to > macrobiotics in that when switching over to a " good " , supportive > behavior > that it's possible you'll get sick in the short-term as you are either > detoxing and/or the toxins are being pushed out of your body? > Would that > be a possible scenario of the below? My experience is that yes, with some things, this does happen. Glutathione, being the body's number one detoxer, is particularly likely to create this in people with high tox loads. Likewise, I have medical proof that I carry a large heavy metal burden, so a recent FIR sauna (which is known to move metal) also wiped me out for several days. (GSH actually helped speed healing in that case.) But in both those cases, it was pretty clear on reflection that my symptoms were because these treatments were creating known reactions against known toxins. Importantly: when I stopped, the symptoms ended in a few days. But, also in my experience, I don't think this " herx " happens nearly as often as other people seem to think it does. I've seen it used to justify treatments that later turned out to be genuinely harmful, or at least highly inappropriate. Apart from the two examples above, when something new makes me feel wretched, it's almost always because it's a Bad Thing and I need to not do it. Recent abortive experiments along this line include Cortef (which I learned the hard way that I don't have the enzymes to clear), testosterone (ditto), and SAMe (ditto ditto). Fortunately, I learned something important from these events, though. Rich was able to piece it together that these three, along with several other problematic drugs, are all cleared by the same enzyme. Obviously, I'm not making that enzyme. Which means that from now on, I'll know to avoid the whole damn family and spare myself future grief. So even wrong turns can be educational, if you're paying attention for the lesson. Then there was salt/c, for which my bad reaction prompted quite a debate here about whether I was in a natural cleansing cycle or unnatural congestive heart failure. (It is a difference worth noting, yes.) I'm still not sure, but you bet I'm gonna be damn careful with this stuff in the future. Moral of the long story: Yes, herxing happens. But I'd tend to assume that most bad reactions are NOT herxes, unless 1) you know for sure that you've got the relevant toxins on board and 2) you know for sure that the new treatment does tend to move those exact toxins. Mostly, pain is still the body's way of saying, " Don't DO that! " Ignoring or enduring it, in the absence of a sound medical reason to do so, has on occasion created massive setbacks that took me weeks or months to heal my way back out of. Sara Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 26, 2006 Report Share Posted July 26, 2006 I personally don't think a whole lot has to be that way. Perhaps with the exception of just the situation you may be in w. the lipo glut. An awful lot seems to be dose-related. For example, the physical therapy I have recently begun. At first it wiped me out profoundly. The wipe out only lasted a few hrs., so I risked going forward. It has been a process of learning not to reach for more than a tiny bit of accomplishment, while at the same time increasing, in tiny increments my ability to accomplish. Voila; after a month, one day I was already in a low place when my p.t. arrived, but I made a tiny effort to do it anyhow- and to my surprise, the d*** exercise energized me. I didn't accomplish much, but I didn't crash big-time either, just a droop about 1/2 hr later. The neat thing is that the prescription my doc wrote is for a whole year, so I don't have to hurry! (I observe a great deal of inclination to hurry and get well on this forum, and I don't think that works with this disease. But I am older than most of the people here, I believe. I still really want a life, but so much has already been consumed by this disease it is not as urgent and I have less time ahead to have great hopes for, so I can afford to be laid back.) At this point I take a whole slew of things for energy, strength and cognition. When I recently added some new things, my response to all the old things started changing. and not in simple ways, because the effects of some of the stuff is cumulative, so that I may find myself in trouble a few days after I quit something altogether and then have to figure out how often to take that thing, not just how much. Right now I am trying to figure out how to get through the evening without either crashing into withdrawals of some sort or another, nor being too energized to sleep. This does not answer your question so directly, I guess, but unless I think the risk is manageable, as with the p.t. or unless I have a good idea of what I am doing, I don't keep up with treatments or processes that make me feel worse. Adrienne Crash on Glutathione then increased energy I wrote earlier about my attempt to take liposomal glutathione. I crashed harder than I have in a long time. For a couple of weeks I thought I had taken a major step backward. Here's the weird part: Now that I've recovered for a few days, I feel more energy than usual. I've been a lurker on this list for 7-8 years with few posts of my own because I usually don't have the energy to join in on the conversation. I have so much energ that this is probably my 5th post in two days. I'm typing like a mad woman. Does anybody think that it could be a longer term effect of the glutathione? I'm wondering if I should start taking it again? Lynn This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2006 Report Share Posted July 27, 2006 Thank you Mercuria. for the answer below TO THOSE IN THE KNOW: Okay, I am struggling over putting what glutathione is, in " english " . I start reading the links and Wikipedia and my eyes glaze over. So here's my shot at " english " -- glutathione is a naturally occurring antioxidant. As an antioxidant, the purpose of glutathione is to help protect and/or rid the body of toxins, such as free radicals. For example, glutathione is needed for the detoxification of <http://en.wikipedia.org/wiki/Methylglyoxal> methylglyoxal, a toxin produced as a by-product of metabolism. When the body has low levels of glutathione, it means that your body's ability to fend off toxins is decreased and as a result, your body's various systems may become overly toxic, thus reducing your natural healing process. Also, when you begin to increase your body's glutathione levels, it may result in a high level of detoxification quickly and you may find your energy and immune system lowered in teh short-term. ???? Am I remotely in the ballpark at a layman's definition? THANK YOU, Laurel Re: Crash on Glutathione then increased energy On Jul 26, 2006, at 9:35 PM, Laurel Ley wrote: > Question: Is trying new therapies and/or processes comparable to > macrobiotics in that when switching over to a " good " , supportive > behavior > that it's possible you'll get sick in the short-term as you are either > detoxing and/or the toxins are being pushed out of your body? > Would that > be a possible scenario of the below? My experience is that yes, with some things, this does happen. Glutathione, being the body's number one detoxer, is particularly likely to create this in people with high tox loads. Likewise, I have medical proof that I carry a large heavy metal burden, so a recent FIR sauna (which is known to move metal) also wiped me out for several days. (GSH actually helped speed healing in that case.) But in both those cases, it was pretty clear on reflection that my symptoms were because these treatments were creating known reactions against known toxins. Importantly: when I stopped, the symptoms ended in a few days. But, also in my experience, I don't think this " herx " happens nearly as often as other people seem to think it does. I've seen it used to justify treatments that later turned out to be genuinely harmful, or at least highly inappropriate. Apart from the two examples above, when something new makes me feel wretched, it's almost always because it's a Bad Thing and I need to not do it. Recent abortive experiments along this line include Cortef (which I learned the hard way that I don't have the enzymes to clear), testosterone (ditto), and SAMe (ditto ditto). Fortunately, I learned something important from these events, though. Rich was able to piece it together that these three, along with several other problematic drugs, are all cleared by the same enzyme. Obviously, I'm not making that enzyme. Which means that from now on, I'll know to avoid the whole damn family and spare myself future grief. So even wrong turns can be educational, if you're paying attention for the lesson. Then there was salt/c, for which my bad reaction prompted quite a debate here about whether I was in a natural cleansing cycle or unnatural congestive heart failure. (It is a difference worth noting, yes.) I'm still not sure, but you bet I'm gonna be damn careful with this stuff in the future. Moral of the long story: Yes, herxing happens. But I'd tend to assume that most bad reactions are NOT herxes, unless 1) you know for sure that you've got the relevant toxins on board and 2) you know for sure that the new treatment does tend to move those exact toxins. Mostly, pain is still the body's way of saying, " Don't DO that! " Ignoring or enduring it, in the absence of a sound medical reason to do so, has on occasion created massive setbacks that took me weeks or months to heal my way back out of. Sara Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2006 Report Share Posted July 27, 2006 Dear Mad Woman, (:-) I think that's possible. The raised glutathione could have helped your detox system and/or your immune system to clear out some things. That may have produced a Herxheimer reaction, which made you feel badly and took some time to clear. As you probably know, historically we have had a difficult time on this list interpreting people's responses to glutathione. Was it a herx? or was it a toxic reaction from too much sulfite or cysteine or mobilization of a toxin, or what? It's difficult to know. But your experiment may be telling you that it did you some good. Rich > > I wrote earlier about my attempt to take liposomal glutathione. I > crashed harder than I have in a long time. For a couple of weeks I > thought I had taken a major step backward. > > Here's the weird part: Now that I've recovered for a few days, I feel > more energy than usual. I've been a lurker on this list for 7-8 years > with few posts of my own because I usually don't have the energy to > join in on the conversation. I have so much energ that this is > probably my 5th post in two days. I'm typing like a mad woman. > > Does anybody think that it could be a longer term effect of the > glutathione? I'm wondering if I should start taking it again? > > Lynn > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2006 Report Share Posted July 27, 2006 Hi, Laurel. I do think that's a possibility in this case, and yes, it does happen. The herxheimer reaction seems to be a real phenomenon. It's not always easy to tell whether that's what's going on when you feel crummy, though. Rich > > Question: Is trying new therapies and/or processes comparable to > macrobiotics in that when switching over to a " good " , supportive behavior > that it's possible you'll get sick in the short-term as you are either > detoxing and/or the toxins are being pushed out of your body? Would that > be a possible scenario of the below? > > I've been wondering this as I start to integrate some suggestion in to my > life. And wondering if I need to prepare for some added " down time " ? > > Thanks, > Laurel > > > Re: Crash on Glutathione then increased energy > > > > In teeny tiny doses, yes. You can't really know unless you try again. It > certainly could've kicked your immune system into action against some > infection and made you feel so bad. But no reason to do it so drastically. > But really, Rich is the glutathione expert. > Adrienne > Crash on Glutathione then increased energy > > I wrote earlier about my attempt to take liposomal glutathione. I > crashed harder than I have in a long time. For a couple of weeks I > thought I had taken a major step backward. > > Here's the weird part: Now that I've recovered for a few days, I feel > more energy than usual. I've been a lurker on this list for 7-8 years > with few posts of my own because I usually don't have the energy to > join in on the conversation. I have so much energ that this is > probably my 5th post in two days. I'm typing like a mad woman. > > Does anybody think that it could be a longer term effect of the > glutathione? I'm wondering if I should start taking it again? > > Lynn > > This list is intended for patients to share personal experiences with each > other, not to give medical advice. If you are interested in any treatment > discussed here, please consult your doctor. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2006 Report Share Posted July 27, 2006 Hi, Laurel. I'd say that's not too bad. I think you've captured the essence of it. If you want to read my attempt at it, it can be found at this website: http://www.cfsresearch.org/cfs/research/treatment/15.htm Pages 2 through 4 describe glutathione, what it does, and how it's made in the body. Rich > > > Question: Is trying new therapies and/or processes comparable to > > macrobiotics in that when switching over to a " good " , supportive > > behavior > > that it's possible you'll get sick in the short-term as you are either > > detoxing and/or the toxins are being pushed out of your body? > > Would that > > be a possible scenario of the below? > > My experience is that yes, with some things, this does happen. > Glutathione, being the body's number one detoxer, is particularly > likely to create this in people with high tox loads. Likewise, I have > medical proof that I carry a large heavy metal burden, so a recent > FIR sauna (which is known to move metal) also wiped me out for > several days. (GSH actually helped speed healing in that case.) But > in both those cases, it was pretty clear on reflection that my > symptoms were because these treatments were creating known reactions > against known toxins. Importantly: when I stopped, the symptoms ended > in a few days. > > But, also in my experience, I don't think this " herx " happens nearly > as often as other people seem to think it does. I've seen it used to > justify treatments that later turned out to be genuinely harmful, or > at least highly inappropriate. Apart from the two examples above, > when something new makes me feel wretched, it's almost always because > it's a Bad Thing and I need to not do it. Recent abortive experiments > along this line include Cortef (which I learned the hard way that I > don't have the enzymes to clear), testosterone (ditto), and SAMe > (ditto ditto). Fortunately, I learned something important from these > events, though. Rich was able to piece it together that these three, > along with several other problematic drugs, are all cleared by the > same enzyme. Obviously, I'm not making that enzyme. Which means that > from now on, I'll know to avoid the whole damn family and spare > myself future grief. So even wrong turns can be educational, if > you're paying attention for the lesson. > > Then there was salt/c, for which my bad reaction prompted quite a > debate here about whether I was in a natural cleansing cycle or > unnatural congestive heart failure. (It is a difference worth noting, > yes.) I'm still not sure, but you bet I'm gonna be damn careful with > this stuff in the future. > > Moral of the long story: Yes, herxing happens. But I'd tend to assume > that most bad reactions are NOT herxes, unless 1) you know for sure > that you've got the relevant toxins on board and 2) you know for sure > that the new treatment does tend to move those exact toxins. Mostly, > pain is still the body's way of saying, " Don't DO that! " Ignoring or > enduring it, in the absence of a sound medical reason to do so, has > on occasion created massive setbacks that took me weeks or months to > heal my way back out of. > > Sara > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2006 Report Share Posted July 27, 2006 Thanks Rich. I'm beaming that it was pretty close. On the link below, it leads to a one-page site that I know i just accessed the other day and the person who ran the site has become too ill to keep it up. I think had given the URL below. And if i recall, it was a bit too technical. i'll keep working my way towards the more comprehending the more complex descriptions. But one thing I've noted about comprehension and memory (probably for people in general but specifically for my illness) -- I have to comprehend something in order to put it in the right place in the file cabinet of my head. So I distill most everything in to layman's terms. Then can start to add different levels of comprehension. Probably speaks to the discussion on IQ and brain power. Laurel Re: Crash on Glutathione then increased energy Hi, Laurel. I'd say that's not too bad. I think you've captured the essence of it. If you want to read my attempt at it, it can be found at this website: http://www.cfsresea <http://www.cfsresearch.org/cfs/research/treatment/15.htm> rch.org/cfs/research/treatment/15.htm Pages 2 through 4 describe glutathione, what it does, and how it's made in the body. Rich > > > Question: Is trying new therapies and/or processes comparable to > > macrobiotics in that when switching over to a " good " , supportive > > behavior > > that it's possible you'll get sick in the short-term as you are either > > detoxing and/or the toxins are being pushed out of your body? > > Would that > > be a possible scenario of the below? > > My experience is that yes, with some things, this does happen. > Glutathione, being the body's number one detoxer, is particularly > likely to create this in people with high tox loads. Likewise, I have > medical proof that I carry a large heavy metal burden, so a recent > FIR sauna (which is known to move metal) also wiped me out for > several days. (GSH actually helped speed healing in that case.) But > in both those cases, it was pretty clear on reflection that my > symptoms were because these treatments were creating known reactions > against known toxins. Importantly: when I stopped, the symptoms ended > in a few days. > > But, also in my experience, I don't think this " herx " happens nearly > as often as other people seem to think it does. I've seen it used to > justify treatments that later turned out to be genuinely harmful, or > at least highly inappropriate. Apart from the two examples above, > when something new makes me feel wretched, it's almost always because > it's a Bad Thing and I need to not do it. Recent abortive experiments > along this line include Cortef (which I learned the hard way that I > don't have the enzymes to clear), testosterone (ditto), and SAMe > (ditto ditto). Fortunately, I learned something important from these > events, though. Rich was able to piece it together that these three, > along with several other problematic drugs, are all cleared by the > same enzyme. Obviously, I'm not making that enzyme. Which means that > from now on, I'll know to avoid the whole damn family and spare > myself future grief. So even wrong turns can be educational, if > you're paying attention for the lesson. > > Then there was salt/c, for which my bad reaction prompted quite a > debate here about whether I was in a natural cleansing cycle or > unnatural congestive heart failure. (It is a difference worth noting, > yes.) I'm still not sure, but you bet I'm gonna be damn careful with > this stuff in the future. > > Moral of the long story: Yes, herxing happens. But I'd tend to assume > that most bad reactions are NOT herxes, unless 1) you know for sure > that you've got the relevant toxins on board and 2) you know for sure > that the new treatment does tend to move those exact toxins. Mostly, > pain is still the body's way of saying, " Don't DO that! " Ignoring or > enduring it, in the absence of a sound medical reason to do so, has > on occasion created massive setbacks that took me weeks or months to > heal my way back out of. > > Sara > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2006 Report Share Posted July 27, 2006 Hi I have tried liposomal glutathione from Wellness during the last couple months. I get very tired from it. I am only taking like 1/3 of a teaspoon. A full teaspoon seems to give me some sort of crash. I am not taking it regularly now, only occasionally and careful with the dose. I dont know, but I think it is important to take alot of Vit. C with it. I started increasing to about 3 grams or more a day and have noticed some improvements, etc I sweat more now. Its summer now ofcourse but I used to never sweat, not even in summer if I remember correctly > I wrote earlier about my attempt to take liposomal glutathione. I > crashed harder than I have in a long time. For a couple of weeks I > thought I had taken a major step backward. > > Here's the weird part: Now that I've recovered for a few days, I feel > more energy than usual. I've been a lurker on this list for 7-8 years > with few posts of my own because I usually don't have the energy to > join in on the conversation. I have so much energ that this is > probably my 5th post in two days. I'm typing like a mad woman. > > Does anybody think that it could be a longer term effect of the > glutathione? I'm wondering if I should start taking it again? > > Lynn > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2006 Report Share Posted July 27, 2006 Rich, You should take any and all info you made available via the website noted below and make it available some other way. (And if you've got an email address for the guy, see if you can get him to repost the old info or send it to someone else for reposting - I have several places where I can put it.) The owner of that ste not only has stopped updating it, he has apparently taken down *ALL* the old content. In addition, he previously had the site blocked for indexing by the http://archive.org people, so the " wayback machine " will not bring it up - anything on that site is lost to us. - Bob Niederman On 7/27/06, rvankonynen <richvank@...> wrote: > > Hi, Laurel. > > I'd say that's not too bad. I think you've captured the essence of > it. If you want to read my attempt at it, it can be found at this > website: > > http://www.cfsresearch.org/cfs/research/treatment/15.htm > > Pages 2 through 4 describe glutathione, what it does, and how it's > made in the body. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2006 Report Share Posted July 27, 2006 On Jul 26, 2006, at 11:25 PM, Laurel Ley wrote: > Thank you Mercuria. for the answer below > > TO THOSE IN THE KNOW: Okay, I am struggling over putting what > glutathione > is, in " english " . I start reading the links and Wikipedia and my > eyes glaze > over. > > So here's my shot at " english " -- glutathione is a naturally occurring > antioxidant. As an antioxidant, the purpose of glutathione is to > help > protect and/or rid the body of toxins, such as free radicals. For > example, > glutathione is needed for the detoxification of > <http://en.wikipedia.org/wiki/Methylglyoxal> methylglyoxal, a toxin > produced > as a by-product of metabolism. When the body has low levels of > glutathione, it means that your body's ability to fend off toxins is > decreased and as a result, your body's various systems may become > overly > toxic, thus reducing your natural healing process. Also, when > you begin > to increase your body's glutathione levels, it may result in a high > level of > detoxification quickly and you may find your energy and immune system > lowered in teh short-term. > > ???? Am I remotely in the ballpark at a layman's definition? You're not only in the ballpark -- you just hit a triple. The only thing missing here is a sense of GSH's truly primary role in detoxification and as an anti-oxidant. There's really nothing else like it. And it doesn't point out how extremely dependent both our energy manufacture (Krebs cycle) and and our immune function are on having adequate quantities around. Other than that, yeah, you're there. We've been known to discuss CFS as " gluthathione deficiency syndrome. " It's a joke, but not too far off the mark. Weird that our doctors know so little about it, isn't it? Sara Quote Link to comment Share on other sites More sharing options...
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