Rich/Methionine plus Taurine

[Guest guest]

Hi Rich

Rich

I was taking Taurine 3 times 500 mg a day. Than I added l-methionine 375 mg

a day for the last 3 or 4 days. I had very strange effect. I was almost

totally bed ridden. Felt extremely exhausted. I am actually not sure if this

is something good for me or bad. I thought I crashed. Symptoms were similar

to crash symptoms.But I had no reason for that other than taking this extra

methionine.I also had increased pulse rate. When I was taking l-methionine

alone I had no problems. It had helped me with mood problems and general

wellbeing.Do you have any idea on what could have happened?I am wondering

what could be the reason for this .I am also taking B12,magnesium and b6.

Thanks.

Nil

[Guest guest]

Hi, Nil.

Perhaps you overloaded your sulfite oxidase enzyme, so that it was

not able to process all the sulfite that was being produced from

breakdown of the taurine and the methionine together. I think this

suggests that you might have a polymorphism in your CBS (cystathione

beta synthase) enzyme, so that too much homocysteine is converted to

cystathionine and goes on down to taurine and sulfite. This seems

to be becoming a more widely observed phenomenon in CFS as people

have started to get the Yasko panel to examine the polymorphisms in

genes for enzymes that impact the methylation cycle.

I would suggest that you cut back on these supplements.

I don't know if it's possible for you to get the Complete Basic SNP

Panel I from http://www.testing4health.com. If not, you might try a

trial and error approach. See message number 102146 that I recently

sent to Rosie.

Rich

>

> Hi Rich

> Rich

> I was taking Taurine 3 times 500 mg a day. Than I added l-

methionine 375 mg

> a day for the last 3 or 4 days. I had very strange effect. I was

almost

> totally bed ridden. Felt extremely exhausted. I am actually not

sure if this

> is something good for me or bad. I thought I crashed. Symptoms

were similar

> to crash symptoms.But I had no reason for that other than taking

this extra

> methionine.I also had increased pulse rate. When I was taking l-

methionine

> alone I had no problems. It had helped me with mood problems and

general

> wellbeing.Do you have any idea on what could have happened?I am

wondering

> what could be the reason for this .I am also taking B12,magnesium

and b6.

> Thanks.

> Nil

>

[Guest guest]

HI Rich,

Maybe the answers to CFS are glutathione and also fingering out how to get it

into the body when the CBS gene is present. Without it we are all suffering

oxidative stress.

Janet

in San Diego

rvankonynen <richvank@...> wrote:

Hi, Nil.

Perhaps you overloaded your sulfite oxidase enzyme, so that it was

not able to process all the sulfite that was being produced from

breakdown of the taurine and the methionine together. I think this

suggests that you might have a polymorphism in your CBS (cystathione

beta synthase) enzyme, so that too much homocysteine is converted to

cystathionine and goes on down to taurine and sulfite. This seems

to be becoming a more widely observed phenomenon in CFS as people

have started to get the Yasko panel to examine the polymorphisms in

genes for enzymes that impact the methylation cycle.

I would suggest that you cut back on these supplements.

I don't know if it's possible for you to get the Complete Basic SNP

Panel I from http://www.testing4health.com. If not, you might try a

trial and error approach. See message number 102146 that I recently

sent to Rosie.

Rich

>

> Hi Rich

> Rich

> I was taking Taurine 3 times 500 mg a day. Than I added l-

methionine 375 mg

> a day for the last 3 or 4 days. I had very strange effect. I was

almost

> totally bed ridden. Felt extremely exhausted. I am actually not

sure if this

> is something good for me or bad. I thought I crashed. Symptoms

were similar

> to crash symptoms.But I had no reason for that other than taking

this extra

> methionine.I also had increased pulse rate. When I was taking l-

methionine

> alone I had no problems. It had helped me with mood problems and

general

> wellbeing.Do you have any idea on what could have happened?I am

wondering

> what could be the reason for this .I am also taking B12,magnesium

and b6.

> Thanks.

> Nil

>

[Guest guest]

Hi, Janet.

I think you're right about that, and in fact, that's the approach Dr.

Yasko is using in CFS. Her emphasis is on dealing with the CBS SNP

first, if present, because otherwise it looks as though the

glutathione might not really come up, and some approaches to raising

it directly can raise cysteine, which is already too high in people

wiwith this SNP. For several years, my emphasis was on getting the

glutathione in in various ways, but that didn't work for everybody.

It's beginning to look as though the CBS SNP may have been at least

one of the reasons. So now that I've heard about that, I've shifted

my focus to be more in line with what Dr. Yasko is doing. It makes

sense to me that a problem higher up in the sulfur metabolism would

cause difficulties with glutathione.

Rich

>

> HI Rich,

>

> Maybe the answers to CFS are glutathione and also fingering out

how to get it into the body when the CBS gene is present. Without it

we are all suffering oxidative stress.

>

> Janet

> in San Diego