[NVIC] Drug resistant HIV strain detected

[Guest guest]

And again, I say, that there is NO proof HIV causes AIDS and this is

another lie.

And I just posted the info on the Hep C lie.

See my webpage http://www.nccn.net/~wwithin/AIDS.htm

Sheri

E-NEWS FROM THE NATIONAL VACCINE INFORMATION CENTER

Vienna, Virginia http://www.nvic.org

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UNITED WAY/COMBINED FEDERAL CAMPAIGN

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" Protecting the health and informed consent rights of children since 1982. "

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BL Fisher Note:

HIV and most blood-transmitted diseases, like hepatitis B, occur in high

risk adult populations. However, when vaccines are created for these

primarily adult diseases, government vaccine policymakers target innocent

children and make the vaccines mandatory. HIV vaccine will be no different.

It will be the children, whose brains and immune systems are still

developing and who have no voice and have no choice, who will bear the

burden and take the vaccine risk for the risk-taking adults.

http://www.nytimes.com/2005/03/30/nyregion/30aids.html

The New York Times

March 30, 2005

Tests Pending in Cases Tied to Fierce H.I.V.

By MARC SANTORA

Investigators looking into the possible spread of a virulent strain of

H.I.V. detected in a New York City man have identified several patients who

may have a related strain of the virus, but the investigators have cautioned

that they cannot yet say if the cases are connected, health officials said

yesterday.

Because of the complexity of the lab testing involved in matching strains of

the virus, it could be months before health officials will be able to

determine if others have indeed been infected with the dangerous strain, the

officials said.

" The extent to which this strain has spread remains under investigation, "

said the city's Department of Health and Mental Hygiene in its first public

statement since issuing a public warning last month about the man's case.

That warning, on Feb. 11, was provoked by the case of a gay man in his late

40's who engaged in unsafe sex with many partners while he was using crystal

methamphetamine, and whose strain of the virus was at once quickly advancing

and resistant to many drugs. The announcement brought an immediate backlash

from some prominent AIDS researchers who believed that too much was being

made of a single case.

Since that time, investigators have been able to trace all of the sexual

partners the man could remember by name and have now closed that part of the

investigation, said Dr. R. Frieden, the city's health commissioner.

The effort involved more than half a dozen investigators going door to door,

but Dr. Frieden would not go into detail about how many people were

contacted, citing patient confidentiality concerns. One person briefed on

the investigation said that more than a dozen men were tracked down.

However, because the patient told investigators that he had sex with more

than a hundred people over several months and could not remember many of

their names, the contact tracing is of limited help.

Of those the department has contacted, many were previously infected with

H.I.V., officials said.

" Obtaining blood samples for resistance testing, and testing of these

samples to determine the genetic relatedness of strains is continuing and

may take weeks to months to complete, " the department said.

Because the investigation is continuing, Dr. Frieden would not say precisely

how the strains that might be related to the New York City case were found.

Some may have been discovered as a result of identifying men with whom the

New York man had sex, but it is just as likely that they were detected in

the department's canvassing of laboratories that do H.I.V. research and

testing.

In all, one health official said, investigators have identified " fewer than

10 " patients whose strains may be related to the New York City man.

Work has already begun, with the help of the Centers for Disease Control in

Atlanta and the Diamond AIDS Research Center in Manhattan, to sequence

the genome of the possibly related cases, Dr. Frieden said.

The source of the New York man's infection remains unknown, officials said.

Health officials said that his case was particularly troubling because it

was the first in which they had seen a strain of the virus that was both

resistant to nearly all drug treatments and highly aggressive, leading

rapidly from H.I.V. infection to AIDS.

The health department's handling of the case, including the public warning,

came under criticism from some prominent AIDS researchers, who suggested

that the rapid progression of the disease might have more to do with the

man's immune system than the aggressiveness of the virus.

Given the heated reaction and the complexity of the scientific questions

involved, it is not surprising that the department has been cautious in

releasing details about the inquiry.

Still, yesterday's update by the department failed to answer a central

question regarding the case: Did the man transmit this new strain to his

sexual partners?

" As of today, no other cases of multi-drug-class resistant, rapidly

progressive H.I.V. have been identified, " health officials said. But that

does not mean that no other cases exist.

The case that set off the alarm involves a man who tested positive for

H.I.V. in December and developed AIDS by January. Investigators say they

believe that he has been infected for as long as 20 months or as little as 4

months. On average, it takes 10 years to develop AIDS after infection, but

the curve is wide, with some people developing AIDS after about 20 years

while others have it progress within a year or so.

The man's virus also showed signs of being resistant to nearly all of the

roughly 20 licensed drug treatments.

Health officials, however, said yesterday that they were encouraged that the

patient seemed to be responding to treatment that includes two licensed

drugs.

" It is probably the most encouraging thing there is about this

investigation, " Dr. Frieden said. Still, the man remains seriously ill.

The update by the department comes after researchers at the Diamond

Center, which alerted the city to the man's case, published a genetic study

of the strain that they said showed it to be unusually aggressive.

But it is the ongoing investigation by the health department in conjunction

with the work being done in laboratories that will ultimately reveal the

strain's significance. It could be months before any definitive conclusions

can be reached, officials said.

In an interview, Dr. Frieden said he remained convinced that the department

made the right decision in issuing an alert.

" It is certainly the case that because we did go public we are more likely

to find future cases as they occur, " he said. He also pointed to some

disturbing behavior patterns the investigation revealed.

" The social network surrounding this case indicates that unsafe, anonymous

sex, along with the use of illicit drugs including crystal methamphetamine,

remains common, " the department said in its stateme

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