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Whooping Cough Vaccine

http://www.healthcentral.com/PrintFormat/PrintFullText2.cfm?id=8009296

Ivanhoe Broadcast News

NASHVILLE, Tenn. (Ivanhoe Broadcast News) -- Pertussis or whooping cough has

been called the hundred-day cough because it can last that long. After a

vaccine was developed in the 1940s, the number of cases dropped, but now it's

rising with as many as 8,000 cases a year. In infants, it can be fatal. Here's

what's being done to protect more babies from the disease.

Four-month-old Hamp visits the doctor today, but his appointment is

special. Hamp is part of a clinical trial that's changing his vaccine schedule.

Normally, a baby starts their series of three whooping cough vaccines at two

months. Hamp got his first dose when he was born.

" We are glad to be in this study, " says Hamp's mother, Anne Marie. " We are

glad to be helping and glad that we can be part of something that might help

children, especially later down the line. "

Pediatrician Natasha Halasa, M.D., says whooping cough is highly contagious.

If infants catch it from an adult, it can turn deadly. That's why the earlier

they start to be protected, the better.

" Kids could actually mount an immune response and get their second vaccine by

two months of age, protecting them earlier, instead of waiting until four

months, where they get the second shot, " Dr. Halasa, of Vanderbilt Children's

Hospital in Nashville, Tenn., tells Ivanhoe.

It happened to 9-month-old Blayne Sands. When he was 5 weeks old, he got

whooping cough and stopped breathing for 21 seconds.

Blayne's mom, Starla, says, " You just cannot explain the fear, the emotion

you go through, the helplessness. " She says, while it's hard to talk about what

happened to her son, she feels it's important to tell parents to take this

disease seriously. " If it is an adult-sounding cough, and they are gasping for

air, they need to be checked out, " she says.

Like many babies, Hamp is not happy about his vaccines. What he doesn't

realize is that the study he's involved in could save babies in the future from

a

dangerous disease.

There are two other options being considered to decrease the number of

whooping cough cases. Researchers are looking at vaccinating women while they

are

pregnant or to add another vaccination during the adolescent years.

This article was reported by Ivanhoe.com, who offers Medical Alerts by e-mail

every day of the week. To subscribe, go to: http://www.ivanhoe.com/newsalert/

..

If you would like more information, please contact:

> Carole Bartoo

> Public Relations Manager

> Vanderbilt Children's Hospital

> 2200 Children's Way, Suite 2515

> Nashville, TN 37232

> (615) 322-4747

> http://www.vanderbilt.edu

>

>

Last Updated: August 16, 2004

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omg, the earlier they give it, the more likely to say that any neuro/health

problems were congenital. Then htey are really out of the liability

because parents will never know what " normal " was to be for their child.

the sheer fact that she's happy to allow her son to be a guinea pig is

enough to make me want to vomit (as does much of the vaccine crap)

in IL

Whooping Cough Vaccine

> Whooping Cough Vaccine

>

> http://www.healthcentral.com/PrintFormat/PrintFullText2.cfm?id=8009296

>

>

> Ivanhoe Broadcast News

>

>

>

> NASHVILLE, Tenn. (Ivanhoe Broadcast News) -- Pertussis or whooping cough

has

> been called the hundred-day cough because it can last that long. After a

> vaccine was developed in the 1940s, the number of cases dropped, but now

it's

> rising with as many as 8,000 cases a year. In infants, it can be fatal.

Here's

> what's being done to protect more babies from the disease.

>

> Four-month-old Hamp visits the doctor today, but his appointment is

> special. Hamp is part of a clinical trial that's changing his vaccine

schedule.

> Normally, a baby starts their series of three whooping cough vaccines at

two

> months. Hamp got his first dose when he was born.

>

> " We are glad to be in this study, " says Hamp's mother, Anne Marie. " We are

> glad to be helping and glad that we can be part of something that might

help

> children, especially later down the line. "

>

> Pediatrician Natasha Halasa, M.D., says whooping cough is highly

contagious.

> If infants catch it from an adult, it can turn deadly. That's why the

earlier

> they start to be protected, the better.

>

> " Kids could actually mount an immune response and get their second vaccine

by

> two months of age, protecting them earlier, instead of waiting until four

> months, where they get the second shot, " Dr. Halasa, of Vanderbilt

Children's

> Hospital in Nashville, Tenn., tells Ivanhoe.

>

> It happened to 9-month-old Blayne Sands. When he was 5 weeks old, he got

> whooping cough and stopped breathing for 21 seconds.

>

> Blayne's mom, Starla, says, " You just cannot explain the fear, the emotion

> you go through, the helplessness. " She says, while it's hard to talk about

what

> happened to her son, she feels it's important to tell parents to take this

> disease seriously. " If it is an adult-sounding cough, and they are gasping

for

> air, they need to be checked out, " she says.

>

> Like many babies, Hamp is not happy about his vaccines. What he doesn't

> realize is that the study he's involved in could save babies in the future

from a

> dangerous disease.

>

> There are two other options being considered to decrease the number of

> whooping cough cases. Researchers are looking at vaccinating women while

they are

> pregnant or to add another vaccination during the adolescent years.

>

> This article was reported by Ivanhoe.com, who offers Medical Alerts by

e-mail

> every day of the week. To subscribe, go to:

http://www.ivanhoe.com/newsalert/

> .

>

> If you would like more information, please contact:

>

>

> > Carole Bartoo

> > Public Relations Manager

> > Vanderbilt Children's Hospital

> > 2200 Children's Way, Suite 2515

> > Nashville, TN 37232

> > (615) 322-4747

> > http://www.vanderbilt.edu

> >

> >

>

>

>

> Last Updated: August 16, 2004

>

>

>

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Hi all, I sent this article to Dr. Sherri, and she asked me to look into the

study more. Thought you may be interested.

http://www.mc.vanderbilt.edu/reporter/?ID=3023

Deadly pertussis focus of VCH study

“I think several strategies would be good to try,†said Halasa. “Pregnant

mothers given the vaccine may pass some protection on to babies, adolescent

boosters would reduce the chances of adolescents or adults giving it to babies,

but we’re about to study how effective it would be to give a baby’s first

pertussis vaccination earlier in life… at birth.â€

Right now Halasa is looking to enroll 50 women who are preparing to deliver

full term babies or healthy infants between the ages 2-14 days who have not yet

received their Hepatitis B vaccination. In this pilot study, 25 newborns will

get the normal Hepatitis B vaccine at birth, while the other 25 will get a

diphtheria, tetanus and acellular pertussis (DTaP) vaccination along with their

Hepatitis B vaccine, that’s two months before the normal schedule to begin

vaccination for pertussis.

The main purpose of this study is to determine if it is safe to administer an

additional dose of the pertussis vaccine in the first days of life and also

to see if babies can mount an adequate immune response. If it is successful,

Halasa hopes an eventual change in the immunization schedule might save

babies’

lives.

For more information on the study email NPVstudy@... or Call Alice

O’Shea at 343-8518.

http://www.vanderbiltchildrens.com/uploads/documents/fall-winter02-03.pdf

“We’re working to design a very careful

pilot trial to look at pertussis immunization

at birth,†says , “to see if we

can speed up the protection we can afford

to children.â€

Another area of concern for the vaccine

research group is how well vaccines protect

children in the community from disease.

For the past three years or so, the

CDC has funded and Dr. Marie

, professor of Preventive Medicine,

to conduct surveillance studies looking at

the incidence of vaccine-preventable diseases,

checking especially to see whether

vaccine protection is long-lived.

The CDC has also funded Vanderbilt to

look at adverse effects associated with

vaccines. These studies are possible

through liaisons with the State

Department of Health and through collaborations

with community pediatricians

who are members of the

Cumberland Pediatric Foundation, a network

of 300 primary care and academic

pediatricians in the Middle Tennessee

area.

“Vanderbilt has had a major role in

evaluating many vaccines for the past

two decades, a role that has been

enhanced by recent CDC and NIH funding

“So this is an exceedingly important

place to look at vaccines,†she says, “to

test the vaccines from the beginning, to

make sure they are safe and effective, to

participate in vaccine licensing and policy

decisions at the FDA and CDC, and

then to follow their safety and their effectiveness

(over the long term).â€

says the work done at

Vanderbilt in disease prevention in children

is remarkable and a strength that

should be applauded.

Dr. Natasha B. Halasa same Dr. in the study

http://www.journals.uchicago.edu/cgi-bin/embpcgi.pl/cgi-bin/res-page.epl?objid=4\

21033

Prevalence of Pertussis Antibodies in Maternal Delivery, Cord, and Infant

Serum

Author(s) C. Healy, Flor M. Munoz, Marcia A. Rench, Natasha B. Halasa,

M. , and Carol J. Baker

Identifiers The Journal of Infectious Diseases, volume 190 (2004), page 335

DOI: 10.1086/421033

PubMed ID: 15216470

Availability This site:   PS  |  HTML  |  PDF (129.0k)  [subscription

required]

Copyright © 2004, the Infectious Diseases Society of America.

Abstract Background.     Passively acquired maternal antibodies protect

infants from many pathogens. With increasing reports of infant pertussis, we

evaluated pertussis antibodies in maternal-infant paired sera from 1999

2000.Methods.     Antibodies to pertussis toxin (PT), filamentous

hemagglutinin (FHA), and

fimbrial proteins (FIM) were measured by validated IgG-specific enzyme-linked

immunosorbant assay (ELISA) in 64 maternalumbilical cord serum pairs and in 61

of 64 infant sera. Geometric mean concentrations (GMCs) of pertussis

antibodies and cord : maternal GMC ratios were

calculated.Results.     Mean maternal

age and gestation were 29.7 years (range, 1942) and 39.3 weeks (range, 35.6

40.9), and 81% of mothers were white. GMCs of maternal antibodies at delivery

(ELISA units/mL) were 2.4 for PT, 6.9 for FHA, and 13 for FIM. Cord GMCs were

169%, 178%, and 157% of maternal delivery values for PT, FHA, and FIM,

respectively, demonstrating active placental transfer (P<.001).

Pertussis-specific IgG

values for each antigen decayed to below the threshold of detection by age 2

months.Conclusions.     Despite efficient placental transfer, low maternal

pertussis antibody levels and their rapid decay in infant sera leave infants

with

little humoral protection against pertussis. These data support the rationale

for maternal or neonatal immunization, with acellular pertussis vaccines, to

prevent life-threatening pertussis in early infancy.

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At Birth???? Those poor poor babies!

--

Aimee, Mom to Marah-Jade Born 09/17/03 vaccine free since 12/03

" Half of the modern drugs could well be thrown out of the window, except that

the birds might eat them. Dr. Henry Fischer "

-------------- Original message --------------

Whooping Cough Vaccine

http://www.healthcentral.com/PrintFormat/PrintFullText2.cfm?id=8009296

Ivanhoe Broadcast News

NASHVILLE, Tenn. (Ivanhoe Broadcast News) -- Pertussis or whooping cough has

been called the hundred-day cough because it can last that long. After a

vaccine was developed in the 1940s, the number of cases dropped, but now it's

rising with as many as 8,000 cases a year. In infants, it can be fatal. Here's

what's being done to protect more babies from the disease.

Four-month-old Hamp visits the doctor today, but his appointment is

special. Hamp is part of a clinical trial that's changing his vaccine schedule.

Normally, a baby starts their series of three whooping cough vaccines at two

months. Hamp got his first dose when he was born.

" We are glad to be in this study, " says Hamp's mother, Anne Marie. " We are

glad to be helping and glad that we can be part of something that might help

children, especially later down the line. "

Pediatrician Natasha Halasa, M.D., says whooping cough is highly contagious.

If infants catch it from an adult, it can turn deadly. That's why the earlier

they start to be protected, the better.

" Kids could actually mount an immune response and get their second vaccine by

two months of age, protecting them earlier, instead of waiting until four

months, where they get the second shot, " Dr. Halasa, of Vanderbilt Children's

Hospital in Nashville, Tenn., tells Ivanhoe.

It happened to 9-month-old Blayne Sands. When he was 5 weeks old, he got

whooping cough and stopped breathing for 21 seconds.

Blayne's mom, Starla, says, " You just cannot explain the fear, the emotion

you go through, the helplessness. " She says, while it's hard to talk about what

happened to her son, she feels it's important to tell parents to take this

disease seriously. " If it is an adult-sounding cough, and they are gasping for

air, they need to be checked out, " she says.

Like many babies, Hamp is not happy about his vaccines. What he doesn't

realize is that the study he's involved in could save babies in the future from

a

dangerous disease.

There are two other options being considered to decrease the number of

whooping cough cases. Researchers are looking at vaccinating women while they

are

pregnant or to add another vaccination during the adolescent years.

This article was reported by Ivanhoe.com, who offers Medical Alerts by e-mail

every day of the week. To subscribe, go to: http://www.ivanhoe.com/newsalert/

..

If you would like more information, please contact:

> Carole Bartoo

> Public Relations Manager

> Vanderbilt Children's Hospital

> 2200 Children's Way, Suite 2515

> Nashville, TN 37232

> (615) 322-4747

> http://www.vanderbilt.edu

>

>

Last Updated: August 16, 2004

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This woman should be charged with child abuse. She handed over her new baby to

be a guinea pig. hhmmm I wonder how she would feel if her baby died from this.

I can hear her interview comments now " I am so proud that my baby could give

his life to test this theory so that other babies might not die from this

terrible disease "

lets all contact this carole bartoo and tell her what a dope she is

Whooping Cough Vaccine

http://www.healthcentral.com/PrintFormat/PrintFullText2.cfm?id=8009296

Four-month-old Hamp visits the doctor today, but his appointment is

special. Hamp is part of a clinical trial that's changing his vaccine schedule.

Normally, a baby starts their series of three whooping cough vaccines at two

months. Hamp got his first dose when he was born.

" We are glad to be in this study, " says Hamp's mother, Anne Marie. " We are

glad to be helping and glad that we can be part of something that might help

children, especially later down the line. "

If you would like more information, please contact:

> Carole Bartoo

> Public Relations Manager

> Vanderbilt Children's Hospital

> 2200 Children's Way, Suite 2515

> Nashville, TN 37232

> (615) 322-4747

> http://www.vanderbilt.edu

>

>

Last Updated: August 16, 2004

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