S.'s case, was: Re: Rich, Kathy: Glutathione buiding and Phase 2 Detox

[Guest guest]

Thanks Rich, having answers is a good thing.

I just started using soy less than a week ago, after Vrchota pushed

the Meta Clear protocol. Prior to that I had been eating a lot of

meat and eggs, which I thought contained a lot of sulfur. I've

continued the renew pro all along and will switch from soy to whey.

The soy protein I'm using I got at my co-op and is certified IPP non-

GMO, what ever that means. Until I got diagnosed with lyme I was

also supplementing pretty generously with MSM, maybe that's

something I should go back to?

I appreciate your other suggestions. It would be great to get my

body fucntioning better before I take on the mercury, wasn't sure I

would be able to if mercury was the problem. Kind of a chicken and

egg situation. - I'm making a concerted effort to eat those

cruciferous vegetables . . . topping them with butter and some well

aged cheese helps a lot!!

S.

> >

> > Hi Rich,

> >

> > Thanks for your response, it was very helpful. I don't think my

> > problem is lack of protein or digestion issues. I've been on a

> high

> > protein diet, with no GI problems at all.

>

> ***I'm glad to hear that you have no G.I. problems. That can be a

> big issue for many PWCs.

>

> (Total protein is 6.3,

> > albumin 3.8)

>

> ***Those blood protein numbers are within the normal ranges, but

on

> the low end. The (relatively tight) normal ranges I use, based on

> Frances Fischbach, A Manual of Laboratory & Diagnostic Tests,

Sixth

> Edition, p. 620, are 6.0 to 8.0 g/dl for total protein, and 3.8 to

> 5.0 g/dl for albumin. So this suggests that you are in fact low

in

> protein.

>

> My guess is it's the kidneys wasting sulfate secondary

> > to mercury. I'll talk to Vrchota about a 24-hour sulfate test.

>

> ***Good. I think that would be a helpful test to run. It's

> possible that the mercury is doing this, but see below about the

> protein situation.

>

> I'm

> > starting to work on getting my amalgams replaced; it's going to

> take

> > a while, probably a year. The MD that's going to detox the

> mercury

> > wants me to come in for a vitamin C flush (35 grams) immediately

> > following my dental appointments.

>

> ***I would suggest holding off on that until your sulfur

metabolism

> is in better shape and your glutathione level has been restored.

> Otherwise, the mercury that is released as vapor and inhaled when

> the amalgams are heated by the drilling will not be bound and

> carried out of your body by glutathione, and this could make you

> much sicker. I have heard many stories from PWCs who have been

> through this, and suffered setbacks that took them months to years

> to get over. Even when a dentist uses precautions such as a high

> volume vacuum line, a dam, and lots of water cooling, it seems

that

> enough mercury is still inhaled to raise the mercury toxicity in

> many PWCs, and the brain seems to receive enough of it to give

them

> neurological symptoms.

> >

> > I am addressing the detox issues by trying to (1) avoid

> > environmental toxic sources and (2) decreasing my total load.

> > Vrchota thought Ultra- Clear would help with that. After

studying

> > the protocol I've decided to adapt some of the principals but

not

> > institute it fully. It's really structured as an elimination

diet

> > for food allergies, which I don't think are an issue for me.

>

> ***Avoiding environmental toxins is very important in your case,

in

> my opinion. I agree on not doing the Ultra-Clear. I think the

> focus needs to be on getting your sulfur metabolism back up to

par.

> >

> > I'm using a powdered soy protein as my main source of protein

> > (eliminating beef, which is easy for me to do, still eating a

> little

> > turkey, chicken, salmon) - total protein intake is about 30

grams

> a

> > day.

>

> ***I'm guessing that you have chosen soy protein to eliminate

toxins

> that may be found in beef. However, soy protein carries some

other

> problems. One is that (unless it's fermented, as the Asians

learned

> to do a long time ago, probably mainly to prevent spoilage, but it

> turns out to have an important other benefit) it contains

substances

> that block the enzyme trypsin in the human digestive tract, and

> thereby interfere with the absorption of amino acids from the

> protein. Another is that soy contains considerable phytate, and

> that binds minerals and prevents their absorption as well. One

> theory for why the Japanese people are smaller in Japan than their

> kids are when they move to the U.S. is that their diets are lower

in

> soy here, so that they are able to absorb more protein and more

> minerals.

>

> ***Another issue with soy protein in the current context is that

it,

> like plant-based protein in general, is not very high in the

sulfur-

> containing amino acids methionine and cysteine. Since you are

able

> to tolerate whey protein well, I would suggest that you switch to

> whey protein instead of soy protein. It doesn't have to be the

more

> expensive types of whey protein isolates or concentrates for use

as

> a bulk protein source for the diet, although including some

RenewPro

> would be a good idea, because that is especially high in cysteine,

> which will help to build glutathione in the liver.

>

> ***The Cecil Textbook of Medicine, 22nd Edition (2004), p. 1308,

> says, " Recommended protein intake is 0.8 g per kg of body weight

per

> day for healthy adults, with essential amino acids contributing a

> relatively small proportion of this total amount. " I don't know

> what your body weight is, but unless you weigh less than 83

pounds,

> I would say that you could use some more protein.

>

> > I've also cut back on my dairy intake which comes mostly in the

> form

> > of cheese

>

> ***Cheese is made from butterfat and casein, and it isn't very

high

> in sulfur-containing amino acids, which are mainly in the whey

> fraction of the milk.

>

> , am increasing veggies (I'm not a big fan of cruciferous

> > vegetables which seems to be recommended to help with each of

> these

> > SNP's)

>

> ***I think that's unfortunate, because the cruciferous vegetables

> are high in sulfur-containing compounds, and you appear to be low

in

> sulfur.

>

> , am going to start DIM (diinodoylmethane),

>

> ***I think that should be helpful.

>

> and have cut out

> > my daily cup of decaf coffee.

>

> ***O.K. That's probably a good idea, though a sacrifice!

>

> > I'm just on oral ceftin 500 mg BID now for antibiotics so I'm

> hoping

> > that helps also

>

> ***I think it will. I don't think ceftin requires CYP450 enzymes

> for its detox.

>

> and am using my sauna almost nightly to induce a

> > good sweat.

>

> ***O.K. Make sure that you supplement minerals, because you can

> lose quite a bit of magnesium, zinc and selenium in the sauna.

When

> you combine that with the phytate in soy, you could go low in

> several minerals unless you supplement them.

>

> > I've increased CSM to 3X daily using a scoop of Renew Life Fiber

> > Smart with each dose (it also contains probiotics).

>

> ***O.K. That should help to get rid of the anionic (negatively

> charged) toxins in your enterohepatic circulation. It will pull

> down your cholesterol, too.

>

> >

> > I don't understand the mechanism of action of the B6 and why it

> made

> > me feel so bad. Did it mobilize toxins that I then could not

> > effectively detox?

>

> ***I suspect that it further depleted the sulfur metabolites in

your

> methylation cycle by speeding up your transsulfuration pathway.

> Sorry about that. I didn't realize that your homocysteine was low

> when I suggested that. I should have waited for that information.

>

> >

> > Genovations should be sending you my full report.

>

> ***Thanks very much.

>

> It's mostly pages

> > of medications I need to avoid. It'll be best if I avoid the OR

> at

> > all costs!!

>

> ***Yes, I hope you can avoid it, too. Based on your

Detoxigenomics

> Profile, you really aren't genetically equipped to do a lot of

heavy

> detoxing of anesthetics or other pharmaceuticals.

>

> ***In view of the above discussion, I do think that you may not be

> getting enough of the sulfur-containing amino acids in your diet,

> and that may be responsible for at least part of the depletion of

> sulfur metabolites in your body. It's also possible that mercury

is

> contributing by blocking the sulfate transporters in your

kidneys.

> It might be interesting to maintain your current diet until you

are

> able to do a 24-hour urine collection to measure sulfate, if Dr.

> Vrchota agrees. That way, we can have a consistent picture to

> analyze. If you switch protein intake now, a sulfate analysis

done

> later would not correspond to the other measurements you already

> have. I would recommend doing the urine sulfate analysis soon,

> though, so that you will not have to delay raising your intake of

> sulfur-containing amino acids.

> >

> > Thanks much,

> >

>

> ***Again, I hope this turns out to be helpful, though I realize

that

> some of it might be kind of chagrining.

>

> Rich

>