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Lymes and Igenex

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I did the Quest Western Blot, and they checked for 10 bands for IgG and 3

bands for IgM. All negative.

Does anyone sense if it would be worthwhile doing Igenex? What would make

them find it when Quest did not? I'd have to pay out-of-pocket and I've not had

some of the Lyme symptoms, so not sure it's worth it in my case.

Jim

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Barbara, I am sorry for what you are going through. There is nothing

worse than having our children suffer.

The tests done at the regular labs are usually not worth doing, as

they do not look at enough bands on the wetern blot and many people

with Lyme get a negative test when they are infected.

If you can afford to use IgeneX get the IgG, IgM and the urine test

with the reverse western blot. Call IgeneX. They have a website, and

ask them for a doctor in Ontario or New York state who is using

their lab.

I hope you can find someone. There is a good doctor in Vancouver, BC

but he is not on the government medical system so can be expensive.

a

> >

> > There are various Igenex tests. Some are relatively use

standard

> blood

> > drawing but in our opinion are more sensative than the

standard

> lab Eliza or

> > Western Blot. These are antibody tests. Other tests are serum

PCR

> which track the

> > Borellia spirochete, the bacteria which causes Lymes Disease.

> > A provocative variation of this is the Igenex LUAT and a newer

> Igenex method.

> > The LUAT (Lymes Urine Antigen Test) requires the patient to

take

> an

> > antibiotic prior to the test to provoke the borellia to die

and

> pass out in the urine.

> > So the order of testing would be the straight serum tests and

if

> negative the

> > provocative test.

> >

> > regards

> > Enlander MD

> > New York

> >

> >

> >

> > In a message dated 2/6/2006 10:43:16 AM Eastern Standard Time,

> > brfifield@ writes:

> > Hi:

> >

> > I just booked an Igenex Lyme test for my son for next week.

They

> didn't

> > mention anything about being on antibiotics first. Should I

> question this? He has

> > been very ill for many years.

> >

> > Thanks,

> > bf

> >

> >

> >

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Rich,

I had a Lyme Dot Blot test, but I don't recall that it was provoked with

antibiotics. Has the procedure changed, or was my test done incorrectly?

Tim

Rich wrote,

" Just a small point concerning the LUAT test: Igenex now offers the

Lyme Dot Blot urine test, which is an upgraded version of the LUAT

test. The LUAT test was impugned by a study sponsored by the

National Institute for Allergy and Infectious Diseases some time

back, and it is no longer offered.

Rich "

>

> There are various Igenex tests. Some are relatively use standard

blood

> drawing but in our opinion are more sensative than the standard

lab Eliza or

> Western Blot. These are antibody tests. Other tests are serum PCR

which track the

> Borellia spirochete, the bacteria which causes Lymes Disease.

> A provocative variation of this is the Igenex LUAT and a newer

Igenex method.

> The LUAT (Lymes Urine Antigen Test) requires the patient to take

an

> antibiotic prior to the test to provoke the borellia to die and

pass out in the urine.

> So the order of testing would be the straight serum tests and if

negative the

> provocative test.

>

> regards

> Enlander MD

> New York

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Hi, Tim.

Here's what it says about that on the Igenex site now:

" What Test(s) to Order

Based on our tracking, as well as input from our client physicians

and our clinical consultant, the initial tests to order for Lyme

disease are the IGeneX IgM and IgG Western Blot and PCRs. The

Western Blots are used to determine if the patient is making

antibodies. Since some patients do not make antibodies, the Lyme

Serum PCR for DNA (# 453) or the Lyme Whole Blood PCR for DNA (#

456) is included in the initial panel.

Thus, the Initial Lyme Panel includes both Western Blots and your

choice of PCR:

Panel 5000:

#s 188, 189 & 453 (PCR—serum)

Panel 5010:

#s188, 189 & 456 (PCR—whole blood)

If the above panel is negative, the follow-up test for Lyme disease

is the Lyme Dot Blot / PCR Panel # 875. This panel looks for pieces

of the bacteria in urine as well as the DNA of Lyme in the urine.

Most physicians use an antibiotic challenge to make the test more

sensitive. The antibiotic protocol, as well as the general

instructions, can be found in the urine testing kit available from

the laboratory. You may also call IGeneX for a copy.

The combination of all of the above tests provides higher than 90%

sensitivity and better than 95% specificity. Remember that Lyme

disease is a clinical diagnosis and testing can support your

clinical presentation.

We also offer tests for the common co-infections of Babesia,

Ehrlichia, and Bartonella. These co-infections are seen in

approximately 20% of the patients with Lyme disease. The usual first

tests to order for the co-infections are IFA antibody tests: # 200

Babesia microti; # 203 or 206 Ehrlichia; and # 285 Bartonella. In

Northern California, Oregon and Washington State, # 710 (Babesia WA-

1) is substituted for # 200 for Babesia antibodies. Panels have been

established for the Midwest/Eastern Region (Panel 5020), the Western

Region (Panel 5040), and the Southern Region (Panel 5050). The FISH

test (# 640) is also used because it is a sensitive indicator of

Babesia infection, even in the absence of antibodies.

Test kits are available with shipping materials at no charge from

IGeneX, Inc. Call 800.832.3200 or e-mail us at

customerservice@...

Dr. Nick S. and J. , MD

June 2005 "

Rich

>

> Rich,

>

> I had a Lyme Dot Blot test, but I don't recall that it was

provoked with

> antibiotics. Has the procedure changed, or was my test done

incorrectly?

>

> Tim

>

> Rich wrote,

>

> " Just a small point concerning the LUAT test: Igenex now offers

the

> Lyme Dot Blot urine test, which is an upgraded version of the LUAT

> test. The LUAT test was impugned by a study sponsored by the

> National Institute for Allergy and Infectious Diseases some time

> back, and it is no longer offered.

>

> Rich "

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On Feb 7, 2006, at 4:51 PM, pjeanneus wrote:

>

> I hope you can find someone. There is a good doctor in Vancouver, BC

> but he is not on the government medical system so can be expensive.

Name, please? I'm looking...

Sara

(in Vancouver)

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Tim, was your test positive? It cannot possibly have been done right

without the antibiotic challenge. Also, it is much more accurate,

about as accurate as you are going to get if they do a reverse

western blot on any positive samples.

a

>

> Rich,

>

> I had a Lyme Dot Blot test, but I don't recall that it was

provoked with

> antibiotics. Has the procedure changed, or was my test done

incorrectly?

>

> Tim

>

> Rich wrote,

>

> " Just a small point concerning the LUAT test: Igenex now offers

the

> Lyme Dot Blot urine test, which is an upgraded version of the LUAT

> test. The LUAT test was impugned by a study sponsored by the

> National Institute for Allergy and Infectious Diseases some time

> back, and it is no longer offered.

>

> Rich "

>

>

> >

> > There are various Igenex tests. Some are relatively use

standard

> blood

> > drawing but in our opinion are more sensative than the standard

> lab Eliza or

> > Western Blot. These are antibody tests. Other tests are serum

PCR

> which track the

> > Borellia spirochete, the bacteria which causes Lymes Disease.

> > A provocative variation of this is the Igenex LUAT and a newer

> Igenex method.

> > The LUAT (Lymes Urine Antigen Test) requires the patient to take

> an

> > antibiotic prior to the test to provoke the borellia to die and

> pass out in the urine.

> > So the order of testing would be the straight serum tests and if

> negative the

> > provocative test.

> >

> > regards

> > Enlander MD

> > New York

>

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Write me off list at pj7@...

We will be in Vancouver in a week - visiting son.

a

>

>

> On Feb 7, 2006, at 4:51 PM, pjeanneus wrote:

>

> >

> > I hope you can find someone. There is a good doctor in Vancouver,

BC

> > but he is not on the government medical system so can be expensive.

>

> Name, please? I'm looking...

>

> Sara

> (in Vancouver)

>

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