Why I am stopping Taurine - A Warning.

[Guest guest]

Well, I gave it a good try. For me it created the following

problems.

1.- Felt anxious. Had idea fixation (like picked a poblem, and

would just try to solve it, over and over again). It had an anxious

life or death urgency to (under Taurine). I almost made a major

decision while being like that. Stopped the Taurine. It stopped

whithin two days Re-started Taurine, and my brain pickeed another

current life stress, and there we went again! Very unpleasant.

Tried 3 times, it was the Taurine.

So you get the idea about what I mean about fixation. I would like

to purchase a car with side impact airbags for my family. They

reduce mortality by 70% in side crashes. It was a nice thought, but

not a necessity. With Taurine, it became central, I was risking by

family's life by not doing that. What could happen on the next trip?

So went looking for Volvo's (expensive) and almost get in more debt

than was reasonable. I was constantly trying to figure out how to

afford it. Stopped the Taurine, my normal self came back. Of course

we all take risks, and having a payment I could not afford was a

greater risk to my family than not having side impac airgbags. Of

course! That is merely logical. The trap stopped when Taurine

stopped. I tried it 3 times, so I KNOW it is the Taurine.

2.- I have to eat almost endlessly when on it. If I do not eat

every two hours or so, I feel very sick. Had this urgency to eat

food or die! As soon as eat, like 3 minutes, it would go away.

3.- Depression. Life felt a lot worse than usual. Normally I am

not depressed. But this thing put me down. The funny thing is that

sometimes it put me in top of a mountain. Then below it. Like a

bipolar thing.

4.- Inability to sleep. Usually I sleep very well. But with the

anxiety caused by the Taurine, I could not. So fixed on trying to

sleep, thus not.

What a mess, all of the above stopped upon discontinuing it. Slowly

stopped.

I am concerned about it affecting others and causing people to make

a rush decision or worse. Think about it. It caused anxiety,

sadness, life looked very gloomy. Get the picture?

Just became unable to deal with little stresses. So be careful. If

you feel unsually sad, or besieged. Try to see if the Taurine is

doing it.

[Guest guest]

I have never taken Taurine, but I might add this thought. I have had

the same reactions when herxing. It is especially a problem when

taking Diflucan. I have to stop because my brain gets so scrambled.

I believe that my brain is one of the last strongholds and when

something manages to cross the bllod brain barrier or even if it is

just toxins from dieoff I got numerous symptoms. Anxiety, poor

judgement, irritability, emotional, etc.

So before you say no Taurine for sure, you might want to try taking

a very small amount, really small. Can you cut it, or open it and

take just a tiny bit. Often treatments are nixed because when we

start herxing people see it as a problem or even allergy with

whatever you are trying. Then very often people find that if they

start really slow and ramp up, they are able to control all of the

negative problems, IF they are actually a herx.

I actually had a lot of these negative affects with Magnesium. I

could have scraped the Mag, but then I found out it was a herx.

Ramped up and sure enough I am doing just fine one it. Just a

thought.

>

> Well, I gave it a good try. For me it created the following

> problems.

>

> 1.- Felt anxious. Had idea fixation (like picked a poblem, and

> would just try to solve it, over and over again). It had an

anxious

> life or death urgency to (under Taurine). I almost made a major

> decision while being like that. Stopped the Taurine. It stopped

> whithin two days Re-started Taurine, and my brain pickeed another

> current life stress, and there we went again! Very unpleasant.

> Tried 3 times, it was the Taurine.

>

> So you get the idea about what I mean about fixation. I would

like

> to purchase a car with side impact airbags for my family. They

> reduce mortality by 70% in side crashes. It was a nice thought,

but

> not a necessity. With Taurine, it became central, I was risking by

> family's life by not doing that. What could happen on the next

trip?

> So went looking for Volvo's (expensive) and almost get in more debt

> than was reasonable. I was constantly trying to figure out how to

> afford it. Stopped the Taurine, my normal self came back. Of

course

> we all take risks, and having a payment I could not afford was a

> greater risk to my family than not having side impac airgbags. Of

> course! That is merely logical. The trap stopped when Taurine

> stopped. I tried it 3 times, so I KNOW it is the Taurine.

>

> 2.- I have to eat almost endlessly when on it. If I do not eat

> every two hours or so, I feel very sick. Had this urgency to eat

> food or die! As soon as eat, like 3 minutes, it would go away.

>

> 3.- Depression. Life felt a lot worse than usual. Normally I am

> not depressed. But this thing put me down. The funny thing is

that

> sometimes it put me in top of a mountain. Then below it. Like a

> bipolar thing.

>

> 4.- Inability to sleep. Usually I sleep very well. But with the

> anxiety caused by the Taurine, I could not. So fixed on trying to

> sleep, thus not.

>

> What a mess, all of the above stopped upon discontinuing it.

Slowly

> stopped.

>

> I am concerned about it affecting others and causing people to

make

> a rush decision or worse. Think about it. It caused anxiety,

> sadness, life looked very gloomy. Get the picture?

>

> Just became unable to deal with little stresses. So be careful.

If

> you feel unsually sad, or besieged. Try to see if the Taurine is

> doing it.

>

[Guest guest]

What form were you taking it in and for what purpose?

I am injecting 1cc a day, with Magnesium.

Has ayone else had this result?

THanks,

Katrina

>

> Well, I gave it a good try. For me it created the following

> problems.

>

> 1.- Felt anxious. Had idea fixation (like picked a poblem, and

> would just try to solve it, over and over again). It had an anxious

> life or death urgency to (under Taurine). I almost made a major

> decision while being like that. Stopped the Taurine. It stopped

> whithin two days Re-started Taurine, and my brain pickeed another

> current life stress, and there we went again! Very unpleasant.

> Tried 3 times, it was the Taurine.

>

> So you get the idea about what I mean about fixation. I would like

> to purchase a car with side impact airbags for my family. They

> reduce mortality by 70% in side crashes. It was a nice thought, but

> not a necessity. With Taurine, it became central, I was risking by

> family's life by not doing that. What could happen on the next trip?

> So went looking for Volvo's (expensive) and almost get in more debt

> than was reasonable. I was constantly trying to figure out how to

> afford it. Stopped the Taurine, my normal self came back. Of course

> we all take risks, and having a payment I could not afford was a

> greater risk to my family than not having side impac airgbags. Of

> course! That is merely logical. The trap stopped when Taurine

> stopped. I tried it 3 times, so I KNOW it is the Taurine.

>

> 2.- I have to eat almost endlessly when on it. If I do not eat

> every two hours or so, I feel very sick. Had this urgency to eat

> food or die! As soon as eat, like 3 minutes, it would go away.

>

> 3.- Depression. Life felt a lot worse than usual. Normally I am

> not depressed. But this thing put me down. The funny thing is that

> sometimes it put me in top of a mountain. Then below it. Like a

> bipolar thing.

>

> 4.- Inability to sleep. Usually I sleep very well. But with the

> anxiety caused by the Taurine, I could not. So fixed on trying to

> sleep, thus not.

>

> What a mess, all of the above stopped upon discontinuing it. Slowly

> stopped.

>

> I am concerned about it affecting others and causing people to make

> a rush decision or worse. Think about it. It caused anxiety,

> sadness, life looked very gloomy. Get the picture?

>

> Just became unable to deal with little stresses. So be careful. If

> you feel unsually sad, or besieged. Try to see if the Taurine is

> doing it.

>

[Guest guest]

Hi Katrina,

> I am injecting 1cc [of taurine] a day, with Magnesium.

I know you've told us this before, but do the taurine and magnesium

come mixed together in a vial or do they come in separate vials? You

say you are injecting 1 cc of taurine each day. Are you also injecting

1 cc of magnesium? Seven days a week?

Did you tell us once that your doctor's rationale for prescribing it

was that the taurine relieved the pain of the magnesium? (Dr. Cheney?)

Do you know of any other doctor who prescribes this? Did you ever try

the magnesium alone so that you could compare?

The reason for all the questions is that my daughter's P.A. has talked

to a local compounding pharmacist about doing taurine and magnesium

together. She told us she'll prescribe it, but would like more

information as it's not something they have done before.

Sue ,

Upstate NY

[Guest guest]

Sue, I am taking magnesium combined with taurine in a pill. Would

that be a problem or is it the shot combo that is the concern?

a

>

> Hi Katrina,

>

> > I am injecting 1cc [of taurine] a day, with Magnesium.

>

> I know you've told us this before, but do the taurine and magnesium

> come mixed together in a vial or do they come in separate vials?

You

> say you are injecting 1 cc of taurine each day. Are you also

injecting

> 1 cc of magnesium? Seven days a week?

>

> Did you tell us once that your doctor's rationale for prescribing

it

> was that the taurine relieved the pain of the magnesium? (Dr.

Cheney?)

> Do you know of any other doctor who prescribes this? Did you ever

try

> the magnesium alone so that you could compare?

>

> The reason for all the questions is that my daughter's P.A. has

talked

> to a local compounding pharmacist about doing taurine and magnesium

> together. She told us she'll prescribe it, but would like more

> information as it's not something they have done before.

>

> Sue ,

> Upstate NY

>

[Guest guest]

a -- I've tried magnesium taurate several times, including the last month or

so. I " m

now convince that it gives me heart palpitations. Happens about 2 hours later,

almost

without fail. If I don't take it -- no palpitations or skipped beats.

Same seems to happen sometimes with magnesium glycinate. Perhaps I've got

enough

magnesium. I have read the if one has a slow, weak heartbeat, then calcium will

help, or

at least a higher ratio than 1/1 cal/mag -- sometimes 3/1 or even 5/1.

We're of course all different, so some will have different results...

Dan

>

> Sue, I am taking magnesium combined with taurine in a pill. Would

> that be a problem or is it the shot combo that is the concern?

>

> a

>

>

> >

> > Hi Katrina,

> >

> > > I am injecting 1cc [of taurine] a day, with Magnesium.

> >

> > I know you've told us this before, but do the taurine and magnesium

> > come mixed together in a vial or do they come in separate vials?

> You

> > say you are injecting 1 cc of taurine each day. Are you also

> injecting

> > 1 cc of magnesium? Seven days a week?

> >

> > Did you tell us once that your doctor's rationale for prescribing

> it

> > was that the taurine relieved the pain of the magnesium? (Dr.

> Cheney?)

> > Do you know of any other doctor who prescribes this? Did you ever

> try

> > the magnesium alone so that you could compare?

> >

> > The reason for all the questions is that my daughter's P.A. has

> talked

> > to a local compounding pharmacist about doing taurine and magnesium

> > together. She told us she'll prescribe it, but would like more

> > information as it's not something they have done before.

> >

> > Sue ,

> > Upstate NY

> >

>

[Guest guest]

Hi a,

>

> Sue, I am taking magnesium combined with taurine in a pill. Would

> that be a problem or is it the shot combo that is the concern?

The doctor just wants a good rationale for injecting (as Katrina does)

the magnesium/taurine as opposed to oral (as you do). IF the taurine

relieves the pain of the magnesium injection and would eliminate the

need for lidocaine, that might be one rationale.

Sue ,

Upstate NY

[Guest guest]

Dan,

Thanks, I will keep this in mind. I have had a few heart palps and

will try to note if they relate to when I take the mag. taurinate. I

am taking Zithromax, Recuperation and mag. taurinate. I also have to

take thyroid meds, so not easy or impossible to sort out what is

helping. I am definitely much better than I have been in about six

years. Now to figure out why.

a

> a -- I've tried magnesium taurate several times, including the

last month or so. I " m

> now convince that it gives me heart palpitations. Happens about 2

hours later, almost

> without fail. If I don't take it -- no palpitations or skipped

beats.

>

> Same seems to happen sometimes with magnesium glycinate. Perhaps

I've got enough

> magnesium. I have read the if one has a slow, weak heartbeat, then

calcium will help, or

> at least a higher ratio than 1/1 cal/mag -- sometimes 3/1 or even

5/1.

>

> We're of course all different, so some will have different results...

>

> Dan

[Guest guest]

Sue:

I will hop in and answer this, because Cheney has me on these

injections. I get three vials from the pharmacy, magnesium, taurine

and lidocaine or some painkiller like that, and I pull them

successively into the needle, mixing them myself. I am supposed to do

the injections 3 x a week or nightly.

Why is more complicated. I think the DFW site goes into that a bit.

Plus in my case he felt the injections would help me with klonopin

w/d and protect me as much is possible from my adrenaline overdrive.

So I try to do them nightly.

Helen

>

> Hi Katrina,

>

> > I am injecting 1cc [of taurine] a day, with Magnesium.

>

> I know you've told us this before, but do the taurine and magnesium

> come mixed together in a vial or do they come in separate vials?

You

> say you are injecting 1 cc of taurine each day. Are you also

injecting

> 1 cc of magnesium? Seven days a week?

>

> Did you tell us once that your doctor's rationale for prescribing

it

> was that the taurine relieved the pain of the magnesium? (Dr.

Cheney?)

> Do you know of any other doctor who prescribes this? Did you ever

try

> the magnesium alone so that you could compare?

>

> The reason for all the questions is that my daughter's P.A. has

talked

> to a local compounding pharmacist about doing taurine and magnesium

> together. She told us she'll prescribe it, but would like more

> information as it's not something they have done before.

>

> Sue ,

> Upstate NY

>

[Guest guest]

Hi Helen,

Are you saying the Klonopin caused the adrenal overdrive? Is that what is

happening when we wake up at 2:30 to 3:00am and can't get back to sleep for till

around 6:00am?

Thanks and Blessings,

Sue T

This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

[Guest guest]

Sue,

In the book " The Canary and Chronic Fatigue Syndrome, " Dr. Majid Ali

says that the oral combination of taurine, potassium and magnesium

is his favorite treatment, because he gets some of his best clinical

results with it.

Rich

>

> Hi Katrina,

>

> > I am injecting 1cc [of taurine] a day, with Magnesium.

>

> I know you've told us this before, but do the taurine and

magnesium

> come mixed together in a vial or do they come in separate vials?

You

> say you are injecting 1 cc of taurine each day. Are you also

injecting

> 1 cc of magnesium? Seven days a week?

>

> Did you tell us once that your doctor's rationale for prescribing

it

> was that the taurine relieved the pain of the magnesium? (Dr.

Cheney?)

> Do you know of any other doctor who prescribes this? Did you ever

try

> the magnesium alone so that you could compare?

>

> The reason for all the questions is that my daughter's P.A. has

talked

> to a local compounding pharmacist about doing taurine and

magnesium

> together. She told us she'll prescribe it, but would like more

> information as it's not something they have done before.

>

> Sue ,

> Upstate NY

>

[Guest guest]

" rvankonynen " wrote:

> In the book " The Canary and Chronic Fatigue Syndrome, " Dr. Majid

Ali says that the oral combination of taurine, potassium and

magnesium is his favorite treatment, because he gets some of his

best clinical results with it.

> Rich

Great efforts have been made to imprint the canary concept upon

CFS, but it's like trying to force a square peg into a round hole.

It doesn't fit the facts.

If a large group of people succumb to CFS simultaneously in a way

that transcends the canary conceptual model, it simply doesn't apply.

Thats like having all the canaries die that are being held in

reserve OUTSIDE the coal mine and saying that the canary concept

still is in effect BECAUSE THEY ARE CANARIES.

The conditions for the " sentinel " nature of the canary concept have

been violated and it doesn't apply.

While some of those who succumbed certainly must have had some

individual susceptibility, if the illness transcends that model and

proves that it strikes indiscriminately, it's like saying that the

illness targets those with a susceptibility except for when it

doesn't - which may be most of the time.

The evidence that the manner of spread is not limited to canaries

shows that the canary concept is the wrong model.

-

[Guest guest]

Hi, .

I hope you have a wonderful day today. Somehow I just don't feel

like getting into it over the canary model today! (:-)

Rich

>

> > In the book " The Canary and Chronic Fatigue Syndrome, " Dr. Majid

> Ali says that the oral combination of taurine, potassium and

> magnesium is his favorite treatment, because he gets some of his

> best clinical results with it.

> > Rich

>

> Great efforts have been made to imprint the canary concept upon

> CFS, but it's like trying to force a square peg into a round hole.

> It doesn't fit the facts.

> If a large group of people succumb to CFS simultaneously in a way

> that transcends the canary conceptual model, it simply doesn't

apply.

> Thats like having all the canaries die that are being held in

> reserve OUTSIDE the coal mine and saying that the canary concept

> still is in effect BECAUSE THEY ARE CANARIES.

> The conditions for the " sentinel " nature of the canary concept

have

> been violated and it doesn't apply.

> While some of those who succumbed certainly must have had some

> individual susceptibility, if the illness transcends that model

and

> proves that it strikes indiscriminately, it's like saying that the

> illness targets those with a susceptibility except for when it

> doesn't - which may be most of the time.

> The evidence that the manner of spread is not limited to canaries

> shows that the canary concept is the wrong model.

> -

>

[Guest guest]

Hi Sue:

Interesting question. Cheney wouldn't say so, but a bunch of people

on the benzo list report adrenaline hyperdrive symptoms. Cheney said

I run on adrenaline to maintain my circulation. The magnesium/taurine

offsets something or other, I don't begin to understand all the

chemical interactions he goes on about, get the video! And since I

discussed the klonopin from hell experience with him at length he did

mention it was particularly important for me to do those injections.

Helen

>

> Hi Helen,

>

> Are you saying the Klonopin caused the adrenal overdrive? Is that

what is happening when we wake up at 2:30 to 3:00am and can't get

back to sleep for till around 6:00am?

>

> Thanks and Blessings,

> Sue T

>

>

>

>

>

>

> This list is intended for patients to share personal experiences

with each other, not to give medical advice. If you are interested

in any treatment discussed here, please consult your doctor.

>

>

>

>

>

[Guest guest]

I want to add some more to this. When I saw Cheney we talked a lot.

The conversation about klonopin and the conversation about adrenaline

occurred at different points in that day. I really don't know what he

would say about the two things. Just that I know a lot of people

going through benzo w/d talk about adrenaline surges and I've had my

share. But I've been running on it for years and before my go-round

with klonopin.

I am remembering Cheney said I have POTS, another heart problem. I

think that has something to do with the adrenaline situation. When I

stand up my body sends out a surge of adrenaline and my heart rate

jumps up immediately by thirty points. I had always thought my pulse

was fast, every time someone takes it, it is up in the 90s. Well, to

my surprise if I'm sitting quietly or better yet lying down,

sometimes it is below 70. It's just from trundling into the doctor's

office that it shoots up.

Helen

> >

> > Hi Helen,

> >

> > Are you saying the Klonopin caused the adrenal overdrive? Is

that

> what is happening when we wake up at 2:30 to 3:00am and can't get

> back to sleep for till around 6:00am?

> >

> > Thanks and Blessings,

> > Sue T

> >

> >

> >

> >

> >

> >

> > This list is intended for patients to share personal experiences

> with each other, not to give medical advice. If you are interested

> in any treatment discussed here, please consult your doctor.

> >

> >

> >

> >

> >

[Guest guest]

I've been taking l-Taurine, 500 nmg 2x/day for two years with NONE of the

reactions you've described below.

How much were you taking and why were you taking it?

Were you also taking it's cofactor, bitamin B6?

Hope this helps

mjh

In a message dated 12/24/2005 3:41:31 PM Eastern Standard Time,

mrraba@... writes:

Well, I gave it a good try. For me it created the following

problems.

1.- Felt anxious. Had idea fixation (like picked a poblem, and

would just try to solve it, over and over again). It had an anxious

life or death urgency to (under Taurine). I almost made a major

decision while being like that. Stopped the Taurine. It stopped

whithin two days Re-started Taurine, and my brain pickeed another

current life stress, and there we went again! Very unpleasant.

Tried 3 times, it was the Taurine.

So you get the idea about what I mean about fixation. I would like

to purchase a car with side impact airbags for my family. They

reduce mortality by 70% in side crashes. It was a nice thought, but

not a necessity. With Taurine, it became central, I was risking by

family's life by not doing that. What could happen on the next trip?

So went looking for Volvo's (expensive) and almost get in more debt

than was reasonable. I was constantly trying to figure out how to

afford it. Stopped the Taurine, my normal self came back. Of course

we all take risks, and having a payment I could not afford was a

greater risk to my family than not having side impac airgbags. Of

course! That is merely logical. The trap stopped when Taurine

stopped. I tried it 3 times, so I KNOW it is the Taurine.

2.- I have to eat almost endlessly when on it. If I do not eat

every two hours or so, I feel very sick. Had this urgency to eat

food or die! As soon as eat, like 3 minutes, it would go away.

3.- Depression. Life felt a lot worse than usual. Normally I am

not depressed. But this thing put me down. The funny thing is that

sometimes it put me in top of a mountain. Then below it. Like a

bipolar thing.

4.- Inability to sleep. Usually I sleep very well. But with the

anxiety caused by the Taurine, I could not. So fixed on trying to

sleep, thus not.

What a mess, all of the above stopped upon discontinuing it. Slowly

stopped.

I am concerned about it affecting others and causing people to make

a rush decision or worse. Think about it. It caused anxiety,

sadness, life looked very gloomy. Get the picture?

Just became unable to deal with little stresses. So be careful. If

you feel unsually sad, or besieged. Try to see if the Taurine is

doing it.

mjh

" The Basil Book "

http://foxhillfarm.us/FireBasil/

[Guest guest]

MarkM

THanks for continuing posting l-Taurine information here, too.

mjh

" The Basil Book "

http://foxhillfarm.us/FireBasil/

[Guest guest]

Hi, mrraba.

This is very puzzling. Your experience would be good to post on

Sulfurstories. My experiences with taurine have been quite the

opposite. I would be a nervous wreck with symptoms much like you

described if I did NOT take taurine. If I have feelings of anxiety

(increased adrenalin), I can take taurine and within 15 minutes or so

they are gone or much improved. I've put an abstract that might

suggest why this is the case.

It also greatly helps me sleep. If I don't take it, I have insomnia.

If I have insomnia and I take it, I have no problem getting to sleep.

This may be due to the fact that taurine may increase the

availability of serotonin and melatonin by stimulating the activity of

n-acetyltransferace (abstract below), but I suspect it has more to do

with reducing the release of adrenalin from the adrenal gland.

There are several studies that discuss taurine's calming effects which

may also be due to its regulatory role in the GABAergic system. I've

put a few abstracts below. I have read in several places that because

it has this calming effect, that it can cause some depressive

symptoms. I haven't experienced this problem.

Are you dealing with any other health issues? It seems like at one

time you mentioned diabetes. What other supplements/medications are

you taking? Maybe they are interacting in some way. How much taurine

were you taking and how often?

I'm slowing putting together some collections of abstracts related to

taurine that will be interesting and hopefully will help us find some

answers. Please don't read my post as doubting your experiences.

It's just that mine have been so positive and most people report a

decrease in anxiety and an increased ability to sleep. Maybe together

we can figure out why you had the negative reaction.

MarkM

Brain Res. 1979 Apr 20;166(1):65-74.

Taurine: stimulation of pineal N-acetyltransferase activity and

melatonin production via a beta-adrenergic mechanism.

Wheler GH, Weller JL, Klein DC.

Pineal glands convert [3H]tryptophan to [3H]N-acetylserotonin and

[3H]melatonin in organ culture. Taurine treatment increases the rate

of production of these compounds 40- and 25-fold respectively by

stimulating the activity of N-acetyltransferase. This stimulation is

blocked stereospecifically by L-propranolol, indicating that taurine

is probably acting via beta-adrenergic receptors. Taurine is active in

stimulating N-acetyltransferase activity in denervated glands,

suggesting that it might interact directly with the beta-adrenergic

receptor, and not by causing the release of norepinephrine from nerve

terminals.

PMID: 217502 [PubMed - indexed for MEDLINE]

Jpn J Pharmacol. 1975 Dec;25(6):737-46.

Effect of taurine on alteration in adrenal functions induced by stress.

Nakagawa K, Kuriyama K.

When rats were exposed to immobilized cold stress, adrenaline

content in the adrenal gland as well as noradrenaline content in the

brain stem were reduced drastically, while noradrenaline content in

the atria was not altered by the application of stress. Oral

administrations of taurine (4-7 g/kg/day, for 3 days) prevented the

stress-induced decline of adrenaline in the adrenal gland and this

preventive effect could not be duplicated by the administration of

L-isoleucine or DL-methionine. In hypophysectomized rats, the stress

also induced a significant fall in adrenaline content of the adrenal

gland, however taurine administration did not show significant

preventive effects on the decline in adrenal catecholamines. The

immobilized cold stress induced a significant increase in blood sugar

and this increase was antagonized by pretreatment with taurine.

Taurine had no significant effects on the stress-induced increase in

the activity of adrenal tyrosine hydroxylase and the turnover rate of

adrenaline in the adrenal gland measured by the rate of decline of

this amine following alpha-methyl-tyrosine administration. The

administration of taurine, in both in vivo and in vitro, inhibited the

release of adrenaline from adrenal medullary granules, but that of

dopamine-beta-hydroxylase was not significantly affected. The

stress-induced elevation of the blood level of corticosterone was not

affected by taurine administration. These findings indicate that

taurine antagonizes the stress-induced elevation of blood sugar by

reducing adrenaline output from the adrenal gland. The regulatory

mechanism most likly involves the inhibition of adrenaline release

from adrenal medullary granules, possibly by stabilizing the membrane

of the granules.

PMID: 6814 [PubMed - indexed for MEDLINE]

FASEB J. 2004 Mar;18(3):511-8.

Taurine prevents the neurotoxicity of beta-amyloid and glutamate

receptor agonists: activation of GABA receptors and possible

implications for Alzheimer's disease and other neurological disorders.

Louzada PR, Lima AC, Mendonca-Silva DL, Noel F, De Mello FG,

Ferreira ST.

Departamento de Bioquimica Medica, Instituto de Ciencias

Biomedicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ

21941-590, Brasil.

Alzheimer's disease (AD) and several other neurological disorders

have been linked to the overactivation of glutamatergic transmission

and excitotoxicity as a common pathway of neuronal injury. The

beta-amyloid peptide (Abeta) is centrally related to the pathogenesis

of AD, and previous reports have demonstrated that the blockade of

glutamate receptors prevents Abeta-induced neuronal death. We show

that taurine, a beta-amino acid found at high concentrations in the

brain, protects chick retinal neurons in culture against the

neurotoxicity of Abeta and glutamate receptor agonists. The protective

effect of taurine is not mediated by interaction with glutamate

receptors, as demonstrated by binding studies using radiolabeled

glutamate receptor ligands. The neuroprotective action of taurine is

blocked by picrotoxin, an antagonist of GABA(A) receptors. GABA and

the GABA(A) receptor agonists phenobarbital and melatonin also protect

neurons against Abeta-induced neurotoxicity. These results suggest

that activation of GABA receptors decreases neuronal vulnerability to

excitotoxic damage and that pharmacological manipulation of the

excitatory and inhibitory neurotransmitter tonus may protect neurons

against a variety of insults. GABAergic transmission may represent a

promising target for the treatment of AD and other neurological

disorders in which excitotoxicity plays a relevant role.

PMID: 15003996 [PubMed - indexed for MEDLINE]

Neurochem Res. 2005 Dec;30(12):1615-21.

Taurine Interaction with Neurotransmitter Receptors in the CNS: An Update.

Albrecht J, Schousboe A.

Department of Neurotoxicology, Medical Research Centre, Polish

Academy of Sciences, Pawinskiego St. 5, 02-106, Warsaw, Poland,

jalb@....

Taurine appears to have multiple functions in the brain

participating both in volume regulation and neurotransmission. In the

latter context it may exert its actions by serving as an agonist at

receptors of the GABAergic and glycinergic neurotransmitter systems.

Its interaction with GABA(A) and GABA( receptors as well as with

glycine receptors is reviewed and the physiological relevance of such

interactions is evaluated. The question as to whether local

extracellular concentrations of taurine are likely to reach the

threshold level for the pertinent receptor populations cannot

presently be answered satisfactorily. Hence more sophisticated

analytical methods are warranted in order to obtain a definite answer

to this important question.

PMID: 16362781 [PubMed - in process]

>

> Well, I gave it a good try. For me it created the following

> problems.

>

> 1.- Felt anxious. Had idea fixation (like picked a poblem, and

> would just try to solve it, over and over again). It had an anxious

> life or death urgency to (under Taurine). I almost made a major

> decision while being like that. Stopped the Taurine. It stopped

> whithin two days Re-started Taurine, and my brain pickeed another

> current life stress, and there we went again! Very unpleasant.

> Tried 3 times, it was the Taurine.

>

> So you get the idea about what I mean about fixation. I would like

> to purchase a car with side impact airbags for my family. They

> reduce mortality by 70% in side crashes. It was a nice thought, but

> not a necessity. With Taurine, it became central, I was risking by

> family's life by not doing that. What could happen on the next trip?

> So went looking for Volvo's (expensive) and almost get in more debt

> than was reasonable. I was constantly trying to figure out how to

> afford it. Stopped the Taurine, my normal self came back. Of course

> we all take risks, and having a payment I could not afford was a

> greater risk to my family than not having side impac airgbags. Of

> course! That is merely logical. The trap stopped when Taurine

> stopped. I tried it 3 times, so I KNOW it is the Taurine.

>

> 2.- I have to eat almost endlessly when on it. If I do not eat

> every two hours or so, I feel very sick. Had this urgency to eat

> food or die! As soon as eat, like 3 minutes, it would go away.

>

> 3.- Depression. Life felt a lot worse than usual. Normally I am

> not depressed. But this thing put me down. The funny thing is that

> sometimes it put me in top of a mountain. Then below it. Like a

> bipolar thing.

>

> 4.- Inability to sleep. Usually I sleep very well. But with the

> anxiety caused by the Taurine, I could not. So fixed on trying to

> sleep, thus not.

>

> What a mess, all of the above stopped upon discontinuing it. Slowly

> stopped.

>

> I am concerned about it affecting others and causing people to make

> a rush decision or worse. Think about it. It caused anxiety,

> sadness, life looked very gloomy. Get the picture?

>

> Just became unable to deal with little stresses. So be careful. If

> you feel unsually sad, or besieged. Try to see if the Taurine is

> doing it.

>

[Guest guest]

Good idea, thanks for suggesting that, I might need to reduce dose.

> >

> > Well, I gave it a good try. For me it created the following

> > problems.

> >

> > 1.- Felt anxious. Had idea fixation (like picked a poblem, and

> > would just try to solve it, over and over again). It had an

> anxious

> > life or death urgency to (under Taurine). I almost made a major

> > decision while being like that. Stopped the Taurine. It

stopped

> > whithin two days Re-started Taurine, and my brain pickeed

another

> > current life stress, and there we went again! Very unpleasant.

> > Tried 3 times, it was the Taurine.

> >

> > So you get the idea about what I mean about fixation. I would

> like

> > to purchase a car with side impact airbags for my family. They

> > reduce mortality by 70% in side crashes. It was a nice thought,

> but

> > not a necessity. With Taurine, it became central, I was risking

by

> > family's life by not doing that. What could happen on the next

> trip?

> > So went looking for Volvo's (expensive) and almost get in more

debt

> > than was reasonable. I was constantly trying to figure out how

to

> > afford it. Stopped the Taurine, my normal self came back. Of

> course

> > we all take risks, and having a payment I could not afford was a

> > greater risk to my family than not having side impac airgbags.

Of

> > course! That is merely logical. The trap stopped when Taurine

> > stopped. I tried it 3 times, so I KNOW it is the Taurine.

> >

> > 2.- I have to eat almost endlessly when on it. If I do not eat

> > every two hours or so, I feel very sick. Had this urgency to

eat

> > food or die! As soon as eat, like 3 minutes, it would go away.

> >

> > 3.- Depression. Life felt a lot worse than usual. Normally I

am

> > not depressed. But this thing put me down. The funny thing is

> that

> > sometimes it put me in top of a mountain. Then below it. Like

a

> > bipolar thing.

> >

> > 4.- Inability to sleep. Usually I sleep very well. But with the

> > anxiety caused by the Taurine, I could not. So fixed on trying

to

> > sleep, thus not.

> >

> > What a mess, all of the above stopped upon discontinuing it.

> Slowly

> > stopped.

> >

> > I am concerned about it affecting others and causing people to

> make

> > a rush decision or worse. Think about it. It caused anxiety,

> > sadness, life looked very gloomy. Get the picture?

> >

> > Just became unable to deal with little stresses. So be

careful.

> If

> > you feel unsually sad, or besieged. Try to see if the Taurine

is

> > doing it.

> >

>

[Guest guest]

I have been taking 1000 mg 2 to 3 times a day. I take recup. It

accentuates the response.

I have had lots of colds lately or allergy reactions not sure which.

It is interesting that you have the opposite reaction. I have been

wondering if my reaction is due to withdrawl, meaning, I should take

more. But I am not trying that since, more makes it worse so far.

It is odd. When I get sick I must eat protein a lot. So the only

thing I can think is different is having a sore throat for 2 weeks

now. Doctor says it is pharyngitis. It gets worse with more

IMUPLUS. That I discovered, means allergy. Since I can really fuel

allergic responses with glutathione. So I reduce the dose of

IMUPLUS when this happens.

I stopped recup for a couple of days. Not permanently, and that

seems to help with the allergy/throat problem.

> >

> > Well, I gave it a good try. For me it created the following

> > problems.

> >

> > 1.- Felt anxious. Had idea fixation (like picked a poblem, and

> > would just try to solve it, over and over again). It had an

anxious

> > life or death urgency to (under Taurine). I almost made a major

> > decision while being like that. Stopped the Taurine. It

stopped

> > whithin two days Re-started Taurine, and my brain pickeed

another

> > current life stress, and there we went again! Very unpleasant.

> > Tried 3 times, it was the Taurine.

> >

> > So you get the idea about what I mean about fixation. I would

like

> > to purchase a car with side impact airbags for my family. They

> > reduce mortality by 70% in side crashes. It was a nice thought,

but

> > not a necessity. With Taurine, it became central, I was risking

by

> > family's life by not doing that. What could happen on the next

trip?

> > So went looking for Volvo's (expensive) and almost get in more

debt

> > than was reasonable. I was constantly trying to figure out how

to

> > afford it. Stopped the Taurine, my normal self came back. Of

course

> > we all take risks, and having a payment I could not afford was a

> > greater risk to my family than not having side impac airgbags.

Of

> > course! That is merely logical. The trap stopped when Taurine

> > stopped. I tried it 3 times, so I KNOW it is the Taurine.

> >

> > 2.- I have to eat almost endlessly when on it. If I do not eat

> > every two hours or so, I feel very sick. Had this urgency to

eat

> > food or die! As soon as eat, like 3 minutes, it would go away.

> >

> > 3.- Depression. Life felt a lot worse than usual. Normally I

am

> > not depressed. But this thing put me down. The funny thing is

that

> > sometimes it put me in top of a mountain. Then below it. Like

a

> > bipolar thing.

> >

> > 4.- Inability to sleep. Usually I sleep very well. But with the

> > anxiety caused by the Taurine, I could not. So fixed on trying

to

> > sleep, thus not.

> >

> > What a mess, all of the above stopped upon discontinuing it.

Slowly

> > stopped.

> >

> > I am concerned about it affecting others and causing people to

make

> > a rush decision or worse. Think about it. It caused anxiety,

> > sadness, life looked very gloomy. Get the picture?

> >

> > Just became unable to deal with little stresses. So be

careful. If

> > you feel unsually sad, or besieged. Try to see if the Taurine

is

> > doing it.

> >

>

[Guest guest]

Except you are missing the whole concept of subgroups. Does anybody really

believe that everyone with CFS has the same illness?

Doris

----- Original Message -----

From: erikmoldwarrior

> In the book " The Canary and Chronic Fatigue Syndrome, " Dr. Majid

Ali says that the oral combination of taurine, potassium and

magnesium is his favorite treatment, because he gets some of his

best clinical results with it.

> Rich

Great efforts have been made to imprint the canary concept upon

CFS, but it's like trying to force a square peg into a round hole.

It doesn't fit the facts.

If a large group of people succumb to CFS simultaneously in a way

that transcends the canary conceptual model, it simply doesn't apply.

Thats like having all the canaries die that are being held in

reserve OUTSIDE the coal mine and saying that the canary concept

still is in effect BECAUSE THEY ARE CANARIES.

The conditions for the " sentinel " nature of the canary concept have

been violated and it doesn't apply.

While some of those who succumbed certainly must have had some

individual susceptibility, if the illness transcends that model and

proves that it strikes indiscriminately, it's like saying that the

illness targets those with a susceptibility except for when it

doesn't - which may be most of the time.

The evidence that the manner of spread is not limited to canaries

shows that the canary concept is the wrong model.

-

[Guest guest]

Hi

I think there are so many variations...

I remember people getting well on Inteferon from so many years ago -

something that I tried and it did not work

Others have high immune systems, other have low. Some have mercury, some

have viral loads

The only common denominator is Glutathione gets whacked and the RnaseL

indicator

justin

Re: Re: Why I am stopping Taurine - A Warning.

Except you are missing the whole concept of subgroups. Does anybody really

believe that everyone with CFS has the same illness?

Doris

----- Original Message -----

From: erikmoldwarrior

> In the book " The Canary and Chronic Fatigue Syndrome, " Dr. Majid

Ali says that the oral combination of taurine, potassium and

magnesium is his favorite treatment, because he gets some of his

best clinical results with it.

> Rich

Great efforts have been made to imprint the canary concept upon

CFS, but it's like trying to force a square peg into a round hole.

It doesn't fit the facts.

If a large group of people succumb to CFS simultaneously in a way

that transcends the canary conceptual model, it simply doesn't apply.

Thats like having all the canaries die that are being held in

reserve OUTSIDE the coal mine and saying that the canary concept

still is in effect BECAUSE THEY ARE CANARIES.

The conditions for the " sentinel " nature of the canary concept have

been violated and it doesn't apply.

While some of those who succumbed certainly must have had some

individual susceptibility, if the illness transcends that model and

proves that it strikes indiscriminately, it's like saying that the

illness targets those with a susceptibility except for when it

doesn't - which may be most of the time.

The evidence that the manner of spread is not limited to canaries

shows that the canary concept is the wrong model.

-

[Guest guest]

I dont' beleive so, too many variations, too many different responses to

treatments, too many different symptoms. I have always believed there are

subgroups.

Marcia

Re: Re: Why I am stopping Taurine - A Warning.

Except you are missing the whole concept of subgroups. Does anybody really

believe that everyone with CFS has the same illness?

Doris

----- Original Message -----

From: erikmoldwarrior

> In the book " The Canary and Chronic Fatigue Syndrome, " Dr. Majid

Ali says that the oral combination of taurine, potassium and

magnesium is his favorite treatment, because he gets some of his

best clinical results with it.

> Rich

Great efforts have been made to imprint the canary concept upon

CFS, but it's like trying to force a square peg into a round hole.

It doesn't fit the facts.

If a large group of people succumb to CFS simultaneously in a way

that transcends the canary conceptual model, it simply doesn't apply.

Thats like having all the canaries die that are being held in

reserve OUTSIDE the coal mine and saying that the canary concept

still is in effect BECAUSE THEY ARE CANARIES.

The conditions for the " sentinel " nature of the canary concept have

been violated and it doesn't apply.

While some of those who succumbed certainly must have had some

individual susceptibility, if the illness transcends that model and

proves that it strikes indiscriminately, it's like saying that the

illness targets those with a susceptibility except for when it

doesn't - which may be most of the time.

The evidence that the manner of spread is not limited to canaries

shows that the canary concept is the wrong model.

-