Creatine, homocysteine, TMG, was Re: for Rich: glutathione/mercury

[Guest guest]

Hi, CS.

The PDR (Physician's Desk Reference) for Nutritional Supplements

says that nausea, diarrhea, indigestion and muscle cramping are

typical or common adverse effects of supplemental creatine. Jon

Pangborn writes that creatine supplementation has been found to help

only about 10% of autistic kids. I guess I would suggest not taking

it if it bothers you.

Pangborn writes that some sources of creatine (such as those used by

bodybuilders) have excessive impurities for autistic kids who do not

detox well [i think this might also apply to PWCs]. He also writes

that if mercury is being mobilized at the time creatine is taken,

the mercury can interfere with the normal phosphorylation of

creatine by the enzymes creatine kinase. He also suggests measuring

the blood level of creatine before supplementing it, because in some

cases it is already too high, perhaps because of a problem with the

creatine transporter system.

Concerning homocysteine, I think that difficulty in remethylating

homocysteine to methionine could be something that is very important

in CFS, and as far as I know, its significance in CFS has not been

fully appreciated by many in the CFS community until now.

Concerning TMG, I suggest that you read what I wrote in an earlier

message this evening, quoting Pangborn.

Rich

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>

> Hi Rich

>

> I recently tried creatine - do you know how to reduce the stomach

cramps

> associated with this ?

>

> Do you think that Homocystein could be the missing link to the CFS

puzzle ?

>

> How important is TMG - ie can you just take high quantities of B

vits or is

> the TMG very important?

>

>

> Regards

> CS

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