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Hi all

Its only one week since I started doing this because my ATP test

showed that I was low in it despite supplementing about 500mg daily

for about 5 years (my RBC magnesium looked ok however when my doctor

tested it in the summer). I don't fully understand why it is that I

tested low for the ATP test but ok on a rbc test maybe Rich might

know how this can happen.

Anyway I am extremely encouraged by my progress, for the past 4 days

I have had energy in my legs I haven't had for years. It doesn't

run out the way it did when walking, I get some uncomfortable pains

in my leg muscles when walking which show they are still having

problems recycling the ATP but they soon recover when I drink the D

Ribose plus Myhill Magic Minerals (soluble solution) (4 times

daily). Also shopping is nothing like the problem it used to be for

me.

I wonder how many others with CFS don't get the amount of magnesium

necessary for their ATP supply by supplements alone? Dr Cheney

writes about this and said that because the blood level of magnesium

is normal the body shunts out any extra magnesium taken in

supplement form before it can be usefully absorbed and therefore is

unavailable for the production of ATP. Certainly this was the case

with me and the difference is amazing.

I should know next week whether heavy metals are adding to or

causing this problem.

Pam

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Hi, Pam.

Thanks for posting this. This is great to hear! I hope things

continue to improve.

It has been found in the past that the level of magnesium in the red

blood cells does not correlate well with the level in tissues.

(Magnesium measured in the blood serum correlates even less well.)

When I wrote the nutrition chapter for the Handbook of CFS that came

out in 2003, I looked into this in some detail. At that time, the

only really reliable way to directly evaluate tissue magnesium

levels was the one offered by one lab in City, California,

which uses cells swabbed from inside the mouth, and analyzes them by

energy dispersive x-ray fluorescence analysis in an electron

microscope. They are called Intracellular Diagnostics, Inc., and

their website is at http://www.exatest.com

It sounds to me as though Dr. 's test, which is a functional

test, rather than a direct test of magnesium, may give them some

competition!

Rich

>

> Hi all

>

> Its only one week since I started doing this because my ATP test

> showed that I was low in it despite supplementing about 500mg

daily

> for about 5 years (my RBC magnesium looked ok however when my

doctor

> tested it in the summer). I don't fully understand why it is that

I

> tested low for the ATP test but ok on a rbc test maybe Rich might

> know how this can happen.

>

> Anyway I am extremely encouraged by my progress, for the past 4

days

> I have had energy in my legs I haven't had for years. It doesn't

> run out the way it did when walking, I get some uncomfortable

pains

> in my leg muscles when walking which show they are still having

> problems recycling the ATP but they soon recover when I drink the

D

> Ribose plus Myhill Magic Minerals (soluble solution) (4 times

> daily). Also shopping is nothing like the problem it used to be

for

> me.

>

> I wonder how many others with CFS don't get the amount of

magnesium

> necessary for their ATP supply by supplements alone? Dr Cheney

> writes about this and said that because the blood level of

magnesium

> is normal the body shunts out any extra magnesium taken in

> supplement form before it can be usefully absorbed and therefore

is

> unavailable for the production of ATP. Certainly this was the

case

> with me and the difference is amazing.

>

> I should know next week whether heavy metals are adding to or

> causing this problem.

>

> Pam

>

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Date: Sat, 12 Nov 2005 16:22:04 -0000

From: " rvankonynen " <richvank@...>

Subject: Re: Nebulising magnesium

Hi, Pam.

Thanks for posting this. This is great to hear! I hope things

continue to improve.

It has been found in the past that the level of magnesium in the red

blood cells does not correlate well with the level in tissues.

(Magnesium measured in the blood serum correlates even less well.)

When I wrote the nutrition chapter for the Handbook of CFS that came

out in 2003, I looked into this in some detail. At that time, the

only really reliable way to directly evaluate tissue magnesium

levels was the one offered by one lab in City, California,

which uses cells swabbed from inside the mouth, and analyzes them by

energy dispersive x-ray fluorescence analysis in an electron

microscope. They are called Intracellular Diagnostics, Inc., and

their website is at http://www.exatest.com

It sounds to me as though Dr. 's test, which is a functional

test, rather than a direct test of magnesium, may give them some

competition!

Rich

..

..

>>> Rich

Is this the same test Carolyn Dean, MD, discusses in her book, The Miracle

of Magnesium, that was developed by a couple of docs in a New York City Med

School?

mjh

" The Basil Book "

http://foxhillfarm.us/FireBasil/

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>

> Hi, Pam.

>

> Thanks for posting this. This is great to hear! I hope things

> continue to improve.

>

> It has been found in the past that the level of magnesium in the

red

> blood cells does not correlate well with the level in tissues.

> (Magnesium measured in the blood serum correlates even less

well.)

> When I wrote the nutrition chapter for the Handbook of CFS that

came

> out in 2003, I looked into this in some detail. At that time, the

> only really reliable way to directly evaluate tissue magnesium

> levels was the one offered by one lab in City, California,

> which uses cells swabbed from inside the mouth, and analyzes them

by

> energy dispersive x-ray fluorescence analysis in an electron

> microscope. They are called Intracellular Diagnostics, Inc., and

> their website is at http://www.exatest.com

>

> It sounds to me as though Dr. 's test, which is a functional

> test, rather than a direct test of magnesium, may give them some

> competition!

>

> Rich

>

Thanks for the explanation Rich regarding blood levels of magnesium

not being consistant with what's in the cells, I wonder how many

doctors know that? (Not many I bet).

I suppose its just like the situation with cortisol where blood

levels might look ok but the saliva tests can show a different story

because they are measuring what is actually at cellular level. Is

it strange that I should have problems with both, ie blood levels

look ok but neither cortisol or magnesium are available to the cells

in sufficient quantity to do their job properly so I need to take

low dose Prednisolone and to get the magnesium by nebulising it? I

wonder if mercury could be the culprit in both cases?

Best Wishes

Pam

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Hi Pam,

Is nebulizing magnesium something we might be able to try without having to

struggle to get a prescription from a doctor? I'm in the US, so I suspect

no one here has even heard of it. Is the purer form of mag sulfate available

through mail order?

Thanks,

Ellen

>>With regard to nebulising the magnesium I just put 1/4 teaspoon of

magnesium sulphate in the nebuliser with 1 teaspoon of water. It

takes about 15 minutes to breath this is through the mouthpiece of the

nebuliser. I just breathe through my mouth to do this and there is

nothing unpleasant about it.

When I first got the nebuliser I didn't have the magnesium sulphate

powder from Dr Myhill so I used Epsom Salts instead but this tended to

make me cough and wouldn't nebulise so well, it took ages and didn't

all get used up. The one Dr Myhill supplies is a purer product I

believe and therefore nebulises much more easily.<<

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>

> Hi Pam,

>

> Is nebulizing magnesium something we might be able to try without

having to

> struggle to get a prescription from a doctor? I'm in the US, so I

suspect

> no one here has even heard of it. Is the purer form of mag sulfate

available

> through mail order?

>

> Thanks,

> Ellen

Hi Ellen

You could try faxing or telephone Dr Myhill's office on the

following numbers-

Tel: 01547 550 331

Fax: 01437 550 339

Of course you will need to put the code in for UK numbers first.

Alternatively you could just use Epsom Salts but it isn't quite so

good at disolving but I am sure it would still get magnesium into

the lungs.

Pam

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Thanks, Pam. Is the problem with epsom salts simply that they don't dissolve

well? Is that what made you cough or are there impurities?

Ellen

> Alternatively you could just use Epsom Salts but it isn't quite so

> good at disolving but I am sure it would still get magnesium into

> the lungs.

>

> Pam

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>

> Thanks, Pam. Is the problem with epsom salts simply that they don't

dissolve

> well? Is that what made you cough or are there impurities?

>

> Ellen

>

Hi Ellen

It was a much firmer powder that didn't seem to disolve quite so well,

I gather the one from Dr Myhill is a purer form but I am sure the

Epsom Salts would work, you might cough a lot more though! They are

both magnesium sulphate.

Pam

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Hi, Ellen and Pam.

I don't know what the impurity situation was in the Epsom salts that

Pam tried, but I would like to emphasize that it's important to make

sure that you use high purity substances when you nebulize into the

lungs.

The reason is that a nebulized puts in droplets that are of

respirable size. That is, they are in the size range that will be

carried down into the alveoli or air sacs in the lungs. The

mucociliary escalator, which clears extraneous matter from the

lungs, does not operate that deeply in the lungs.

So if you put an impurity in the alveoli, it must be dealt with by

the alveolar macrophages, which use their chemicals to try to

dissolve it and carry it away in the blood, to be disposed of by the

detox sytem.

The problem is that some impurities, such as silicon dioxide

(basically, sand) cannot be dissolved by the macrophages. If there

is very much of this, it can end up producing interstitial pulmonary

fibrosis.

What happens there is that the fibroblasts come in and build

a " cocoon " around the impurity particle to wall it off from the

body, since it can't be removed. The problem is that it does this in

the interstitial space, between the wall of the alveolus and the

blood capillaries, which is where you are trying to move oxygen in

and carbon dioxide out. If too much of this occurs, the person

cannot get enough oxygen into their blood.

The bottom line is that I would suggest getting high purity

magnesium sulfate for nebulizing. I haven't looked into sources,

but I'm sure there are some.

Rich

> >

> > Thanks, Pam. Is the problem with epsom salts simply that they

don't

> dissolve

> > well? Is that what made you cough or are there impurities?

> >

> > Ellen

> >

> Hi Ellen

>

> It was a much firmer powder that didn't seem to disolve quite so

well,

> I gather the one from Dr Myhill is a purer form but I am sure the

> Epsom Salts would work, you might cough a lot more though! They

are

> both magnesium sulphate.

>

> Pam

>

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Ellen, Pam and the group,

One more thing. You also don't want to produce bacterial infections

in the lungs by nebulizing. Therefore, boiling the solution before

using it would be a good idea, unless it is sold as a sterile

solution.

Rich

> >

> > Thanks, Pam. Is the problem with epsom salts simply that they

don't

> dissolve

> > well? Is that what made you cough or are there impurities?

> >

> > Ellen

> >

> Hi Ellen

>

> It was a much firmer powder that didn't seem to disolve quite so

well,

> I gather the one from Dr Myhill is a purer form but I am sure the

> Epsom Salts would work, you might cough a lot more though! They

are

> both magnesium sulphate.

>

> Pam

>

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