Guest guest Posted April 20, 2005 Report Share Posted April 20, 2005 I know what you mean about the increased NO helping to fight infection. I think Cheney believes an unfortunate consequence of this NO is ultimately peroxynitrite production and damage to the mitochondria in the heart cells. So while NO is attempting to fight the infection that is infecting the cells it is also damaging them! You just cant win for losing. Of course the immune system can do a tremendous amount of damage if it is upregulated or misdirected for a period of time. Cheney's theories - and most CFS theories - are logical but based on little evidence - no one has examined heart cell mitochondria that I know of., Dr. Lerner has some, but not alot of evidence of heart infection, no one knows about heavy metal contamination of the heart cells - the theory consists of a long string of logical but unproven inferences. Of course thats all he has to go on given the state of CFS research. Pall's theory makes sense - there is evidence for it - but almost no work has been down actually studying it. Its a shame kdrbrill <kdrbrill@...> wrote: > > L-Arginine always seems to get a bad rap when it comes to > CFIDS, because it is a precursor to nitric oxide, and some > research has shown elevated NO levels in some patients with > CFIDS, plus, it also competes with l-lysine, which is purported to > have anti-viral properties. > > After the recent discussion re Dr. Cheney's heart disease > hypothesis however, I'm wondering if the elevated NO levels are > the body's natural attempt to address the heart disease or > bolster the immune function? > > After all, NO is essential for killing off bugs, germs, bacteria, etc., > plus, NO is essential for proper cardiovascular function. This > review of studies from 1966-2000 seems to support the use of > l-arginine in those with cardiovascular disease: > > http://www.theannals.com/cgi/content/abstract/35/6/755 > > L-arginine in the management of cardiovascular diseases > JW Cheng, SN Baldwin, and SN Balwin > > > OBJECTIVE: To examine the role of L-arginine in the > management of cardiovascular diseases. DATA SOURCES: A > MEDLINE search (1966-April 2000) of review articles, using the > search terms arginine, nitric oxide, and cardiovascular diseases, > was conducted. After reviewing these articles, primary studies > using the search terms arginine, hypercholesterolemia, > hypertension, diabetes, smoking, ischemic heart disease, and > heart failure were reviewed. STUDY SELECTION: > English-language human studies were selected and evaluated > based on quality of review. DATA SYNTHESIS: Small-scale > studies have demonstrated that intravenous L-arginine > augments endothelial function by enhancing vasodilation and > reducing monocyte adhesion. Oral supplementation > demonstrated similar effects as well as improvement of exercise > ability in patients with cardiovascular diseases. CONCLUSIONS: > L-arginine improves the management of multiple cardiovascular > diseases. However, most published human studies are small. > Before therapy can be routinely recommended, larger, > well-designed studies are required to confirm its effect. " > > Personally, I took l-arginine/l-orthinine back in early 2001 for > about 2 months. I felt much better for about 6-7 months after > that. (I was also taking SAM-e, and a few other things, but the > supplement I haven't taken in years is l-arginine.) > > Just putting this out there for discussion. > > Dan > > > > > > This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. > > > > --------------------------------- > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 20, 2005 Report Share Posted April 20, 2005 This is interesting. I just read that Candida holds on to heavy metals, and when it is killed off suddenly, such as with treatments, the heavy metals are released suddenly and can cause damage to organs. Does anyone know if a candida infection would cause increased NO levels? Re: Cheney, Heart Disease, CFIDS and...ARGININE? I believe it is. Cheney said he believes the 'nexus' of this disease has to do with infections and heavy metals and damage to the heart. The increased NO levels come from iNOS responding to infection. SInce the infection is never completely resolved increased NO becomes chronic. You wouldnt think taking arginine would help since it increases NO levels. There are different kinds of NO though - perhaps it assisted endothelial NO and helped microcirculatory blood flows by opening the blood vessels??? Who knows? Maybe we are NO increased in one area and NO decreased - wouldn't that be great. NO is just going to remain a big mystery until we get some extensive studies on it in CFS. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 20, 2005 Report Share Posted April 20, 2005 Does > anyone know if a candida infection would cause increased NO levels? Hi Kurt, I don't KNOW, but I would assume it might. But would that be a bad thing or a good thing -- the body's natural attempt to fight the candida overgrowth? I remember a message posted by a woman who had had CFIDS and fibro for 23 years. She said the treatment that gave her the most benefit, especially energy-wise, was food-grade hydrogen peroxide (starting with one drop in a glass of water 3 times a day, and working up to 9 drops) along with some antioxidants. What does hydrogen peroxide do? It releases a LOT of nitric oxide... d. > > Re: Cheney, Heart Disease, CFIDS > and...ARGININE? > > I believe it is. Cheney said he believes the 'nexus' of this disease > has to do with infections and heavy metals and damage to the heart. The > increased NO levels come from iNOS responding to infection. SInce the > infection is never completely resolved increased NO becomes chronic. > > You wouldnt think taking arginine would help since it increases NO > levels. There are different kinds of NO though - perhaps it assisted > endothelial NO and helped microcirculatory blood flows by opening the > blood vessels??? Who knows? Maybe we are NO increased in one area and > NO decreased - wouldn't that be great. NO is just going to remain a big > mystery until we get some extensive studies on it in CFS. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 20, 2005 Report Share Posted April 20, 2005 Interesting. I have a relative who was a patient of Cheney and had a very bad case of CFIDS. She went through years of Cheney treatment and improved marginally enough to be functional again, but not well. Then she met up with an alt med practitioner who insisted that his patients were getting well from H2O2. So she took the peroxide as IV for a few months, I believe a week or two apart. It was a miserable experience, she was very glad to finish the regimen. But she got completely well. She has a life now. I don't know if it will last, but so far so good (this was over a year ago). I don't think she knows why it worked, but she was classic CFIDS per Cheney, with DI, etc. Might be interesting to find out what H2O2 does - is it the NO? Or maybe does it kill a blood-borne infection, maybe candida or something like that? --Kurt Re: Cheney, Heart Disease, CFIDS > and...ARGININE? > > I believe it is. Cheney said he believes the 'nexus' of this disease > has to do with infections and heavy metals and damage to the heart. The > increased NO levels come from iNOS responding to infection. SInce the > infection is never completely resolved increased NO becomes chronic. > > You wouldnt think taking arginine would help since it increases NO > levels. There are different kinds of NO though - perhaps it assisted > endothelial NO and helped microcirculatory blood flows by opening the > blood vessels??? Who knows? Maybe we are NO increased in one area and > NO decreased - wouldn't that be great. NO is just going to remain a big > mystery until we get some extensive studies on it in CFS. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 20, 2005 Report Share Posted April 20, 2005 I was interested in this H2O2 treatment until I googled it and came across a story about someone who died after having intravenous H2O2. Helen > Does > > anyone know if a candida infection would cause increased NO > levels? > > Hi Kurt, > > I don't KNOW, but I would assume it might. But would that be a > bad thing or a good thing -- the body's natural attempt to fight the > candida overgrowth? > > I remember a message posted by a woman who had had CFIDS > and fibro for 23 years. She said the treatment that gave her the > most benefit, especially energy-wise, was food-grade hydrogen > peroxide (starting with one drop in a glass of water 3 times a > day, and working up to 9 drops) along with some antioxidants. > > What does hydrogen peroxide do? It releases a LOT of nitric > oxide... > > d. > > > > > > Re: Cheney, Heart Disease, > CFIDS > > and...ARGININE? > > > > I believe it is. Cheney said he believes the 'nexus' of this > disease > > has to do with infections and heavy metals and damage to the > heart. The > > increased NO levels come from iNOS responding to infection. > SInce the > > infection is never completely resolved increased NO becomes > chronic. > > > > You wouldnt think taking arginine would help since it increases > NO > > levels. There are different kinds of NO though - perhaps it > assisted > > endothelial NO and helped microcirculatory blood flows by > opening the > > blood vessels??? Who knows? Maybe we are NO increased > in one area and > > NO decreased - wouldn't that be great. NO is just going to > remain a big > > mystery until we get some extensive studies on it in CFS. > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 20, 2005 Report Share Posted April 20, 2005 > > I was interested in this H2O2 treatment until I googled it and came > across a story about someone who died after having intravenous H2O2. > > Helen Helen, Once again.............what is good for one person may be rotten for another. A friend of mine who has cfs also had H202 IV treatments and it actually made her worse. I am glad it worked for Kurts' relative but we all must tread with caution. Tammy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 20, 2005 Report Share Posted April 20, 2005 I believe it kills pathogens. I took it early on - about 20 years ago. My doctor did it as a last resort. It didnt do anything positive or negative then. When I saw Dr. Rea - who treats MS, one of his assistants said I was lucky it didnt kill me. Obviously its very controversial . As I remember H202 is a mild oxidant; as it devolves, however, I think it can create alot of free radicals. Maybe thats how it kills the pathogens. helen9jora <helen9jora@...> wrote: I was interested in this H2O2 treatment until I googled it and came across a story about someone who died after having intravenous H2O2. Helen > Does > > anyone know if a candida infection would cause increased NO > levels? > > Hi Kurt, > > I don't KNOW, but I would assume it might. But would that be a > bad thing or a good thing -- the body's natural attempt to fight the > candida overgrowth? > > I remember a message posted by a woman who had had CFIDS > and fibro for 23 years. She said the treatment that gave her the > most benefit, especially energy-wise, was food-grade hydrogen > peroxide (starting with one drop in a glass of water 3 times a > day, and working up to 9 drops) along with some antioxidants. > > What does hydrogen peroxide do? It releases a LOT of nitric > oxide... > > d. > > > > > > Re: Cheney, Heart Disease, > CFIDS > > and...ARGININE? > > > > I believe it is. Cheney said he believes the 'nexus' of this > disease > > has to do with infections and heavy metals and damage to the > heart. The > > increased NO levels come from iNOS responding to infection. > SInce the > > infection is never completely resolved increased NO becomes > chronic. > > > > You wouldnt think taking arginine would help since it increases > NO > > levels. There are different kinds of NO though - perhaps it > assisted > > endothelial NO and helped microcirculatory blood flows by > opening the > > blood vessels??? Who knows? Maybe we are NO increased > in one area and > > NO decreased - wouldn't that be great. NO is just going to > remain a big > > mystery until we get some extensive studies on it in CFS. > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 21, 2005 Report Share Posted April 21, 2005 I think there probably have been MANY unreported cases of death from H2O2. Even though I have one relative who got well from H2O2, it was a very difficult experience for her. But there is another story, also in my extended family (the step-father of one of my brothers-in-law to be precise) of a probable death from H2O2. He was being treated with IV H2O2, and was not improving. He was in his late 50s or early 60s I believe. The practitioner insisted that he was about to 'turn the corner' and just needed more. So he relented, he was really 'into' alternative medicine, and the practitioner increased the dose. He died that week of a strange and unknown cause. Impossible to pin down what really happened, but the correlation with the H2O2 treatment is undeniable. My brother-in-law believes the H2O2 was the cause. He will never know for sure of course. The problem is that many deaths like this, from many treatments, not just H2O2, are not properly classified. I think you practically have to die in your doctor's office minutes after a treatment to get these things properly classified. Even then they will find ways to attribute the death to other causes, or 'pre-existing' conditions. And this happens throughout all health-care, probably even more common in 'mainstream' medicine. And many drug trials result in test subject deaths, and almost always the deaths are attributed to other causes. But the drug certainly helped them out the door. Anyway, there are lots of cases of death on both sides of this aisle. I don't really want to get too morbid, we all will die sooner or later, we are just trying to make that later, right? :-) There are always risks, and in my opinion a simple rule is the stronger the therapy, the greater the risk. H2O2 can be either strong or weak, depends on how you approach the therapy. I like gentle and gradual therapies. We can only 'evolve' our own body so fast towards better health. --Kurt Re: Re: Cheney, Heart Disease, CFIDS and...ARGININE? IV H2O2 is perfectly safe as along as it is properly adminerstered. There has been one case of death, this was not due to to the h2o2 but other causes relating to his medications. Mainstream medicine has jumped on this ONE case, when thousdands of people die annually from 'properly' prescribed medications. Blake cort johnson wrote: .. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 21, 2005 Report Share Posted April 21, 2005 IV H2O2 is perfectly safe as along as it is properly adminerstered. There has been one case of death, this was not due to to the h2o2 but other causes relating to his medications. Mainstream medicine has jumped on this ONE case, when thousdands of people die annually from 'properly' prescribed medications. Blake cort johnson wrote: > I believe it kills pathogens. I took it early on - about 20 years > ago. My doctor did it as a last resort. It didnt do anything > positive or negative then. When I saw Dr. Rea - who treats MS, one of > his assistants said I was lucky it didnt kill me. Obviously its very > controversial . As I remember H202 is a mild oxidant; as it devolves, > however, I think it can create alot of free radicals. Maybe thats how > it kills the pathogens. > > helen9jora <helen9jora@...> wrote: > I was interested in this H2O2 treatment until I googled it and came > across a story about someone who died after having intravenous H2O2. > > Helen > > > > > Does > > > anyone know if a candida infection would cause increased NO > > levels? > > > > Hi Kurt, > > > > I don't KNOW, but I would assume it might. But would that be a > > bad thing or a good thing -- the body's natural attempt to fight > the > > candida overgrowth? > > > > I remember a message posted by a woman who had had CFIDS > > and fibro for 23 years. She said the treatment that gave her the > > most benefit, especially energy-wise, was food-grade hydrogen > > peroxide (starting with one drop in a glass of water 3 times a > > day, and working up to 9 drops) along with some antioxidants. > > > > What does hydrogen peroxide do? It releases a LOT of nitric > > oxide... > > > > d. > > > > > > > > > > Re: Cheney, Heart Disease, > > CFIDS > > > and...ARGININE? > > > > > > I believe it is. Cheney said he believes the 'nexus' of this > > disease > > > has to do with infections and heavy metals and damage to the > > heart. The > > > increased NO levels come from iNOS responding to infection. > > SInce the > > > infection is never completely resolved increased NO becomes > > chronic. > > > > > > You wouldnt think taking arginine would help since it increases > > NO > > > levels. There are different kinds of NO though - perhaps it > > assisted > > > endothelial NO and helped microcirculatory blood flows by > > opening the > > > blood vessels??? Who knows? Maybe we are NO increased > > in one area and > > > NO decreased - wouldn't that be great. NO is just going to > > remain a big > > > mystery until we get some extensive studies on it in CFS. > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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