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Re: Glutathione: Lipoceutical vs Whey

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--- In , Hi, Al,

Good point. In terms of symptom relief and quantitative data showing

glutathione repletion, I also would love to know the difference between

lipoceutical glutathione and a nondenatured whey such as Renewpro recently

suggested by Rich. In particular for the lipoceutical glutathione, I would be

willing to go in with a group of patients as sort of an informal experimental

study if you will where we pay the at cost rate for say 90 days of Wellness

Health's expensive brand of this if they would be willing to strike such a deal.

I know Rich has stated that he submitted his AACFS 2004 Conference paper on

glutathione depletion in CFS to this manufacturer along a similar line of

thought in suggesting they consider testing it with PWCs, but I have not seen

any mention of them responding.

I am interested in drilling down and thoroughly escavating the possibilities for

glutathione repletion given Rich's compelling argument that glutathione

depletion is a central defect in CFS pathophysiology in a substantial fraction

of this patient population.

If not the whole solution, I think its important to get this glutathione

depletion to glutathione repletion task effectively accomplished somehow before

jumping around in trying to handle too many already brow beaten tangental

issues. Accomplishing this may yield huge benefits towards us getting well and

even failure in the attempt to do this could yield new superior insight into CFS

pathophysiology beyond what is currently possible.

Superior treatment follows superior pathophysiologic insight.

I've seen Lipoceutical Glutathione mentioned on this list, but has anyone tried

it and compared it to whey protein in elevating Glutathione levels ?

>

> Which is better ?

>

> Dr. Cheney only liked Whey, but that was based on his old lectures. I wonder

if he knows about the Lipoceutical Glutathione.

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,

So far I have recieved a brief response from Wellness Health, saying

that the person I wrote to had been out of town for a while, but was

now back, and still plans to respond.

Rich

>

> --- In , Hi, Al,

>

>

>

> Good point. In terms of symptom relief and quantitative data

showing glutathione repletion, I also would love to know the

difference between lipoceutical glutathione and a nondenatured whey

such as Renewpro recently suggested by Rich. In particular for the

lipoceutical glutathione, I would be willing to go in with a group

of patients as sort of an informal experimental study if you will

where we pay the at cost rate for say 90 days of Wellness Health's

expensive brand of this if they would be willing to strike such a

deal.

>

>

>

> I know Rich has stated that he submitted his AACFS 2004 Conference

paper on glutathione depletion in CFS to this manufacturer along a

similar line of thought in suggesting they consider testing it with

PWCs, but I have not seen any mention of them responding.

> I am interested in drilling down and thoroughly escavating the

possibilities for glutathione repletion given Rich's compelling

argument that glutathione depletion is a central defect in CFS

pathophysiology in a substantial fraction of this patient population.

>

>

>

> If not the whole solution, I think its important to get this

glutathione depletion to glutathione repletion task effectively

accomplished somehow before jumping around in trying to handle too

many already brow beaten tangental issues. Accomplishing this may

yield huge benefits towards us getting well and even failure in the

attempt to do this could yield new superior insight into CFS

pathophysiology beyond what is currently possible.

>

>

>

> Superior treatment follows superior pathophysiologic insight.

>

>

>

>

>

>

>

>

> I've seen Lipoceutical Glutathione mentioned on this list, but has

anyone tried it and compared it to whey protein in elevating

Glutathione levels ?

> >

> > Which is better ?

> >

> > Dr. Cheney only liked Whey, but that was based on his old

lectures. I wonder if he knows about the Lipoceutical Glutathione.

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Hi Rich, Al and list:

I'm trying the lipoceutical glutathione at the dose they recommended. I

started on Wednesday, Feb. 9. So far, no relief from symptoms. But I'll keep

the list informed.

Naomi

Glutathione: Lipoceutical vs Whey

>

> Hi all,

>

> I've seen Lipoceutical Glutathione mentioned on this list, but has

anyone tried it and compared it to whey protein in elevating Glutathione

levels ?

>

> Which is better ?

>

> Dr. Cheney only liked Whey, but that was based on his old lectures. I

wonder if he knows about the Lipoceutical Glutathione.

>

>

> Thanks,

> Al

>

>

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I started using the LipoCeutical glutathione a few days ago, slowly

working up to the recommended dosage. I'm noticing a heavy sulfur,

rotten egg type odor now when I open the bottle. The product

literature says that it has a shelf life of 2 years and does not need

refrigeration, so I'm guessing the odor is normal??

Sandy

> Hi Rich, Al and list:

>

> I'm trying the lipoceutical glutathione at the dose they

recommended. I

> started on Wednesday, Feb. 9. So far, no relief from symptoms. But

I'll keep

> the list informed.

>

> Naomi

> Glutathione: Lipoceutical vs Whey

>

>

> >

> > Hi all,

> >

> > I've seen Lipoceutical Glutathione mentioned on this list,

but has

> anyone tried it and compared it to whey protein in elevating

Glutathione

> levels ?

> >

> > Which is better ?

> >

> > Dr. Cheney only liked Whey, but that was based on his old

lectures. I

> wonder if he knows about the Lipoceutical Glutathione.

> >

> >

> > Thanks,

> > Al

> >

> >

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>

> I started using the LipoCeutical glutathione a few days ago,

slowly

> working up to the recommended dosage. I'm noticing a heavy

sulfur,

> rotten egg type odor now when I open the bottle. The product

> literature says that it has a shelf life of 2 years and does not

need

> refrigeration, so I'm guessing the odor is normal??

>

> Sandy > > >

Sandy,

I once ordered some amino acids that smelled like rotten

eggs............I thought I had purchased a batch that went bad

until I called the company I bought it from and they said the smell

was normal........because of the sulfur compounds.''

Let us know how you get on with the Lipo-Glutathione.

Tammy

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Naomi,

O.K., I'll be interested to hear what your experience is.

Rich

> Hi Rich, Al and list:

>

> I'm trying the lipoceutical glutathione at the dose they

recommended. I

> started on Wednesday, Feb. 9. So far, no relief from symptoms. But

I'll keep

> the list informed.

>

> Naomi

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Hi, Sandy.

Glutathione is chemically reactive, and I think it's difficult to

prevent some reaction from taking place, even though it is protected

by phospholipid membranes in this product. I think the smell

results from hydrogen sulfide gas, but other sulfur compounds may be

involved, too.

Rich

> > Hi Rich, Al and list:

> >

> > I'm trying the lipoceutical glutathione at the dose they

> recommended. I

> > started on Wednesday, Feb. 9. So far, no relief from symptoms.

But

> I'll keep

> > the list informed.

> >

> > Naomi

> > Glutathione: Lipoceutical vs Whey

> >

> >

> > >

> > > Hi all,

> > >

> > > I've seen Lipoceutical Glutathione mentioned on this list,

> but has

> > anyone tried it and compared it to whey protein in elevating

> Glutathione

> > levels ?

> > >

> > > Which is better ?

> > >

> > > Dr. Cheney only liked Whey, but that was based on his old

> lectures. I

> > wonder if he knows about the Lipoceutical Glutathione.

> > >

> > >

> > > Thanks,

> > > Al

> > >

> > >

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Hi, Sandy.

I did some homework, and now I can give you a better answer.

In the paper Marrades, R.M. et al., Nebulized Glutathione Induces

Bronchoconstriction in Patients with Mild Asthma, " Am J Respir Care

Med 156, 435-430 (1997), it says the following: " ...glutathione is a

highly hydrophilic substance containing cysteine, an amino acid with

a sulfhydryl group. When either sulfur species dissolves in aqueous

solutions, a pH-dependent equilibrium is established among different

sulfites (sulfur dioxide [sO2], metabisulfite [sO5--], bisulfite

[sO3-], sulfite [sO3--]). These sulfites produce the

characteristic 'rotten eggs' smell of glutathione solution... "

So it sounds as though they're saying that whenever glutathione is

dissolved in water, this smell is produced, and it is apparently due

to other sulfur compounds than hydrogen sulfide.

Rich

> > > Hi Rich, Al and list:

> > >

> > > I'm trying the lipoceutical glutathione at the dose they

> > recommended. I

> > > started on Wednesday, Feb. 9. So far, no relief from symptoms.

> But

> > I'll keep

> > > the list informed.

> > >

> > > Naomi

> > > Glutathione: Lipoceutical vs Whey

> > >

> > >

> > > >

> > > > Hi all,

> > > >

> > > > I've seen Lipoceutical Glutathione mentioned on this

list,

> > but has

> > > anyone tried it and compared it to whey protein in elevating

> > Glutathione

> > > levels ?

> > > >

> > > > Which is better ?

> > > >

> > > > Dr. Cheney only liked Whey, but that was based on his old

> > lectures. I

> > > wonder if he knows about the Lipoceutical Glutathione.

> > > >

> > > >

> > > > Thanks,

> > > > Al

> > > >

> > > >

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Hi Rich,

Thanks very much for the explanation and for taking the time to

research.

Sandy

>

> Hi, Sandy.

>

> I did some homework, and now I can give you a better answer.

>

> In the paper Marrades, R.M. et al., Nebulized Glutathione Induces

> Bronchoconstriction in Patients with Mild Asthma, " Am J Respir Care

> Med 156, 435-430 (1997), it says the following: " ...glutathione is

a

> highly hydrophilic substance containing cysteine, an amino acid

with

> a sulfhydryl group. When either sulfur species dissolves in

aqueous

> solutions, a pH-dependent equilibrium is established among

different

> sulfites (sulfur dioxide [sO2], metabisulfite [sO5--], bisulfite

> [sO3-], sulfite [sO3--]). These sulfites produce the

> characteristic 'rotten eggs' smell of glutathione solution... "

>

> So it sounds as though they're saying that whenever glutathione is

> dissolved in water, this smell is produced, and it is apparently

due

> to other sulfur compounds than hydrogen sulfide.

>

> Rich

>

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