Guest guest Posted August 20, 2004 Report Share Posted August 20, 2004 Hi Rich I wonder if you could give me your thoughts on my recent live blood analysis with a private doctor here in the UK. My red blood cells and the plasma looked extremely healthy so much so the doctor said it was very unusual to see such healthy looking blood on the first visit and thought it was due to all the work/supplements I have done. There were a few rbc which were too large and he said I was borderline in suffering with low B12 and therefore gave me a shot of B12. This had been confired previously by a urine analysis I did last year. With regard to the white blood cells he mentioned that the neutrophils were extremely lazy and not moving around as they should. He felt this could be a big problem in my having borrelia and possibly co-infections and has asked me to take a supplement containing both taurine and glutamine. He thinks the taurine will help to make the neutrophils more active. There was no sign of Candida and definitely no hypercoagulation whatsoever but there were several parasites and he said this was sign of a leaky gut, hence the glutamine. He also felt the mercury poisoning I have had contributed to the lazy neutrophils and weak immune system. He also believes that my weak adrenals going back 30 years have weakened me considerably (after loosing 4 pints of blood immediately after childbirth) and wants me to go back up to 5mg Deltacortril for the next 6 months. Also I am to continue with the Armour 2 1/2 grains - 3 grains daily. Already I can feel my muscles in my legs benefiting from the extra Prednisolone (extra 2.5mg). All in all he said it was all very encourging and he feels that with this extra supplement which is also designed to boost glutathione levels plus the 300mg Doxycycline every other day the borrelia should be dealt with in 6 months. He is of the opinion that if one has a strong immune system and good nutrition then bugs like borrelia shouldn't be too much of a problem to be dealt with with 6 months of Doxy (time will tell on that one). I am also taking Cats Claw tea 3 times daily and will continue with this regime plus the Doxy because it has helped me a lot. I do herx badly from time to time so it proves there are bacteria to be killed off but inbetween I can feel very well with lots of energy. I would be very grateful of your opinion especially with regard to " lazy " neutrophils. Best Wishes Pam Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 22, 2004 Report Share Posted August 22, 2004 Hi, Pam. It's really amazing how much can be learned when an experienced person looks at a live blood sample! It's nice to hear that your blood generally looked very good. The large red cells indicating B12 deficiency makes sense, and it sounds as though that agrees with other test results. The parasites, leaky gut and glutamine also make sense. As I recall, you have gotten considerable benefit before from low dose steroid treatment. It sounds as though you may need it, alright. I think you are well aware of the importance of keeping the dose as low as you can while getting the benefit, and trying to get back off it after a while to see if your adrenals might be able to pick up the load by themselves. The Armour thyroid sounds O.K., too. You can probably tell by armpit temperature readings as well as how you feel, how much is enough. Adrenal and thyroid deficiencies tend to occur together. I don't know if the long-term doxy will be able to knock out the Lyme or not. You are probably aware of the Marshall protocol. I don't know whether you have had your vitamin D metabolites measured, but I've read that it's difficult to get that done in the U.K. If the doxy doesn't seem to knock it out, you might want to consider looking into the Marshall protocol, and in particular, maybe the vitamin D metabolite tests will become more readily available in the U.K., so that you could get them and then be able to tell if this protocol would have a good chance of benefiting you. Concerning the " lazy " neutrophils, I think it's impressive that your doctor has looked at enough neutrophils to distinguish " lazy " ones from more agressive ones! In regard to the effect of taurine on neutrophils (also known as polymorphonuclear leukocytes), I have a copy of a recent review paper on taurine (Schuller-Levis, G.B., and Park, E., FEMS Microbiology Letters 226 (2003) 195-202), and it discusses some interesting work in cats. As you may know, cats are not able to make their own taurine, and must get it from their food if they are to be healthy. Consequently, taurine deficiency can be studied relatively easily in cats (not a terribly kind thing to do to the cats, but anyway, that's the story). Here's what it says: " A lack of taurine in the diet of cats resulted in a significant leukopenia, a shift in the percentage of polymorphonuclear and mononuclear leukocytes, an increase in the absolute counts of mononuclear leukocytes, and a change in the sedimentation characteristics of white cells. Functional studies of polymorphonuclear cells isolated from cats fed taurine-free diets demonstrated a significant decrease in the respiratory burst as measured by chemiluminescence as well as a decrease in phagocytosis of Staphyloccus epidermidis compared to cats fet the same diet containing taurine. " Well, it doesn't exactly talk about the neutrophils being " lazy, " but since producing respiratory bursts and swallowing (phagocytosing) bacteria are big parts of their job description, it might be fair to say that they were " lazy. " I suppose that your doctor has experience indicating that adding taurine will help to invigorate the neutrophils. This sounds at least plausible. There may be other things that can make them " lazy, " but this sounds as though it's worth a try. Since taurine is a sulfur-containing amino acid, and since a person with low glutathione will thus tend to be low in taurine as well, and since you've had mercury issues, which tend to be associated with low glutathione, this story seems to fit together. I'll be interested to hear whether you develop Olympic-class neutrophils from this treatment! Rich > Hi Rich > > I wonder if you could give me your thoughts on my recent live blood > analysis with a private doctor here in the UK. > > My red blood cells and the plasma looked extremely healthy so much > so the doctor said it was very unusual to see such healthy looking > blood on the first visit and thought it was due to all the > work/supplements I have done. There were a few rbc which were too > large and he said I was borderline in suffering with low B12 and > therefore gave me a shot of B12. This had been confired previously > by a urine analysis I did last year. > > With regard to the white blood cells he mentioned that the > neutrophils were extremely lazy and not moving around as they > should. He felt this could be a big problem in my having borrelia > and possibly co-infections and has asked me to take a supplement > containing both taurine and glutamine. He thinks the taurine will > help to make the neutrophils more active. > > There was no sign of Candida and definitely no hypercoagulation > whatsoever but there were several parasites and he said this was > sign of a leaky gut, hence the glutamine. > > He also felt the mercury poisoning I have had contributed to the > lazy neutrophils and weak immune system. He also believes that my > weak adrenals going back 30 years have weakened me considerably > (after loosing 4 pints of blood immediately after childbirth) and > wants me to go back up to 5mg Deltacortril for the next 6 months. > Also I am to continue with the Armour 2 1/2 grains - 3 grains daily. > > Already I can feel my muscles in my legs benefiting from the extra > Prednisolone (extra 2.5mg). > > All in all he said it was all very encourging and he feels that with > this extra supplement which is also designed to boost glutathione > levels plus the 300mg Doxycycline every other day the borrelia > should be dealt with in 6 months. He is of the opinion that if one > has a strong immune system and good nutrition then bugs like > borrelia shouldn't be too much of a problem to be dealt with with 6 > months of Doxy (time will tell on that one). > > I am also taking Cats Claw tea 3 times daily and will continue with > this regime plus the Doxy because it has helped me a lot. I do herx > badly from time to time so it proves there are bacteria to be killed > off but inbetween I can feel very well with lots of energy. > > I would be very grateful of your opinion especially with regard > to " lazy " neutrophils. > > Best Wishes > > Pam Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2004 Report Share Posted August 23, 2004 > Hi, Pam. > > It's really amazing how much can be learned when an experienced > person looks at a live blood sample! > > It's nice to hear that your blood generally looked very good. The > large red cells indicating B12 deficiency makes sense, and it sounds > as though that agrees with other test results. > > The parasites, leaky gut and glutamine also make sense. > > As I recall, you have gotten considerable benefit before from low > dose steroid treatment. It sounds as though you may need it, > alright. I think you are well aware of the importance of keeping > the dose as low as you can while getting the benefit, and trying to > get back off it after a while to see if your adrenals might be able > to pick up the load by themselves. The Armour thyroid sounds O.K., > too. You can probably tell by armpit temperature readings as well > as how you feel, how much is enough. Adrenal and thyroid > deficiencies tend to occur together. > > I don't know if the long-term doxy will be able to knock out the > Lyme or not. You are probably aware of the Marshall protocol. I > don't know whether you have had your vitamin D metabolites measured, > but I've read that it's difficult to get that done in the U.K. If > the doxy doesn't seem to knock it out, you might want to consider > looking into the Marshall protocol, and in particular, maybe the > vitamin D metabolite tests will become more readily available in the > U.K., so that you could get them and then be able to tell if this > protocol would have a good chance of benefiting you. > > Concerning the " lazy " neutrophils, I think it's impressive that your > doctor has looked at enough neutrophils to distinguish " lazy " ones > from more agressive ones! In regard to the effect of taurine on > neutrophils (also known as polymorphonuclear leukocytes), I have a > copy of a recent review paper on taurine (Schuller-Levis, G.B., and > Park, E., FEMS Microbiology Letters 226 (2003) 195-202), and it > discusses some interesting work in cats. As you may know, cats are > not able to make their own taurine, and must get it from their food > if they are to be healthy. Consequently, taurine deficiency can be > studied relatively easily in cats (not a terribly kind thing to do > to the cats, but anyway, that's the story). Here's what it says: > > " A lack of taurine in the diet of cats resulted in a significant > leukopenia, a shift in the percentage of polymorphonuclear and > mononuclear leukocytes, an increase in the absolute counts of > mononuclear leukocytes, and a change in the sedimentation > characteristics of white cells. Functional studies of > polymorphonuclear cells isolated from cats fed taurine-free diets > demonstrated a significant decrease in the respiratory burst as > measured by chemiluminescence as well as a decrease in phagocytosis > of Staphyloccus epidermidis compared to cats fet the same diet > containing taurine. " > > Well, it doesn't exactly talk about the neutrophils being " lazy, " > but since producing respiratory bursts and swallowing > (phagocytosing) bacteria are big parts of their job description, it > might be fair to say that they were " lazy. " > > I suppose that your doctor has experience indicating that adding > taurine will help to invigorate the neutrophils. This sounds at > least plausible. There may be other things that can make > them " lazy, " but this sounds as though it's worth a try. Since > taurine is a sulfur-containing amino acid, and since a person with > low glutathione will thus tend to be low in taurine as well, and > since you've had mercury issues, which tend to be associated with > low glutathione, this story seems to fit together. I'll be > interested to hear whether you develop Olympic-class neutrophils > from this treatment! > > Rich > Hi Rich Thanks so much for your reply and the info re taurine. I am not sure if I mentioned it previously but the doctor also thought the fact I had been mercury poisoned would have affected the neurophils and that mercury might still be causing a bit of a problem. He suggested that it would be a good idea to do more chelation and I will try alpha lipoic acid in rounds again. I have been on the Doxy/Cats Claw for nearly 6 weeks now and my body seems to be getting very used to them. There seems to be the occasional day when I ache like mad and I develop a sore throat for a while but in general I seem to be feeling very well and my muscles are the best they have been in a very long time. Even after my evening walk my legs feel relatively normal which is so unusal for me. I rather guess this is to do with the increased steroid. This is since seeing my doctor last week and I wonder if it could also be a result of the B12 injection, I'm not sure about that though. What I have been doing is taking my usual 2.5 mg Deltacortril dose one day and the next day taking double the dose. It does make me feel rather cross to think that my inability to walk for the last 6 years was a result of my untreated adrenals/thyroid, still I do consider my fortunate to at least found it out at last. Thanks for all your help Rich and I am following the MP info but feel that in general time will tell whether it helps people with CFS. I still cannot see how it can help with heavy metal problems and I feel sure I am not the only one who has been poisoned by their dental amalgams. Best Wishes Pam Quote Link to comment Share on other sites More sharing options...
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