Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 Can methylcobalamin be injected? I have, regretably, developed an apparent allergy to my hydroxocobalamin injections after using them successfully for over a year. My allergist is unwilling to take a chance on letting me inject cyanocobalamin again, considering the literature indicating that, although allergic response to B12 is very rare, it causes anaphlaxis. Anybody have any idea what I can do instead of an injection every fourth night? Thanks. LaRue B12 Injections > > > Hi all > > I have just started to receive B12 injections from my GP in the UK to > which at this stage he has suggested that I have it once a month. > > I would be insterested to know if there are any papers or information > stating to how many one should receive (within a month), that I could > pass onto him for the guidance management > > My GP is not a ME consultant yet does have a huge interest in the > field of CFS/ME and is happy for me to search for information that > may be relevant to correct dosage. > > Thanks in advance > > e > > dx 3 years > > > > This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 There are sublingual forms of methyl and hydroxycobalamin. Thanks Nil B12 Injections > > > > > > Hi all > > > > I have just started to receive B12 injections from my GP in the UK to > > which at this stage he has suggested that I have it once a month. > > > > I would be insterested to know if there are any papers or information > > stating to how many one should receive (within a month), that I could > > pass onto him for the guidance management > > > > My GP is not a ME consultant yet does have a huge interest in the > > field of CFS/ME and is happy for me to search for information that > > may be relevant to correct dosage. > > > > Thanks in advance > > > > e > > > > dx 3 years > > > > > > > > This list is intended for patients to share personal experiences with > each other, not to give medical advice. If you are interested in any > treatment discussed here, please consult your doctor. > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 Yes, methylc can be injected. You might be reacting to the preservative rather than to the b12 itself? Is the reaction local or all over, or systemic? If it is the b12 itself you are allergic to, what diference would it make how you took it? I believe I read b12 can be transported thru the skin by means of DMSO. Adrienne B12 Injections > > > Hi all > > I have just started to receive B12 injections from my GP in the UK to > which at this stage he has suggested that I have it once a month. > > I would be insterested to know if there are any papers or information > stating to how many one should receive (within a month), that I could > pass onto him for the guidance management > > My GP is not a ME consultant yet does have a huge interest in the > field of CFS/ME and is happy for me to search for information that > may be relevant to correct dosage. > > Thanks in advance > > e > > dx 3 years > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 I had a reaction to the preservative in my hydroxycobalamin after taking it for several years. I'm taking preservative free now, with no problems. Don't know what your reaction was, I had hives from the alcohol preservative. You also could try a different pharmacy. Laurie On Wednesday, January 7, 2004, at 03:06 PM, SloanLL wrote: > Can methylcobalamin be injected? I have, regretably, developed an > apparent > allergy to my hydroxocobalamin injections after using them > successfully for > over a year. My allergist is unwilling to take a chance on letting me > inject > cyanocobalamin again, considering the literature indicating that, > although > allergic response to B12 is very rare, it causes anaphlaxis. Anybody > have > any idea what I can do instead of an injection every fourth night? > Thanks. > LaRue > B12 Injections >> >> >> Hi all >> >> I have just started to receive B12 injections from my GP in the UK >> to >> which at this stage he has suggested that I have it once a month. >> >> I would be insterested to know if there are any papers or >> information >> stating to how many one should receive (within a month), that I >> could >> pass onto him for the guidance management >> >> My GP is not a ME consultant yet does have a huge interest in the >> field of CFS/ME and is happy for me to search for information that >> may be relevant to correct dosage. >> >> Thanks in advance >> >> e >> >> dx 3 years >> >> >> >> This list is intended for patients to share personal experiences >> with > each other, not to give medical advice. If you are interested in any > treatment discussed here, please consult your doctor. >> >> >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 My hydroxycobalamin contains 10 mg Benzyl alcohol 2 mg sodium tartarate 0,3 mg tartaric acid 10 mg Lidocain hcl 3 mg Propil Gallat Do you think these amounts are significant enough to effect me adversely? Thanks. Nil Re: B12 Injections Help, please > I had a reaction to the preservative in my hydroxycobalamin after > taking it for several years. I'm taking preservative free now, with no > problems. > > Don't know what your reaction was, I had hives from the alcohol Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 Methylcobalamin is also available in sublingual form. Supposedly sublingual has been found to be as effective as IM injections at raising B12 levels, but those studies that found this were for individuals who had B12 deficiencies, and does not mean that therapeutic levels could be reached sublingually. However, I have done both IM injections and sublingual hydroxycobalamin, and found that while the sublingual only lasted half as long as the effects from the IM injected, the effects I experienced from it seemed to be twice as strong. In other words, more was absorbed much quicker, but it was probably excreted more quickly than the IM injection. My own personal balance seemed to be for me to use half as much sublingually, but take it twice as often to get the same results. So if you were doing twice weekly injections, you might want to take half as much four times per week. My experiments were using the same stuff that I was using for IM injections, and just using it sublingually by squirting it into my mouth, rather than injecting it into the muscle, and holding it in my mouth and under my tongue as much as possible for several minutes. I try to do it sublingually after eating a meal, so that any that I swallowed might possibly still get absorbed intestinally if possible. I've tried methylcobalamin that was specifically designed to be taken sublingually, and didn't see any benefits from it. I don't know if the ingredients inhibited it's absorption, or if it was the form that wasn't of benefit to me. But I did have some concerns about using the methylcobalamin form, and especially sublingually. There has been some discussion on other lists that I'm on that the methyl form could react with mercury in the mouth from amalgam fillings, forming methyl mercury, which is tons more toxic than mercury alone. So taking methylmercury sublingually might pose a problem for individuals that still have amalgam fillings. lindaj@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 Nil; Do you feel an adverse reaction or a benefit from your injections? Adrienne From: Nil Subject: Re: B12 Injections Help, please My hydroxycobalamin contains 10 mg Benzyl alcohol 2 mg sodium tartarate 0,3 mg tartaric acid 10 mg Lidocain hcl 3 mg Propil Gallat Do you think these amounts are significant enough to effect me adversely? Thanks. Nil Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 I seem to be getting worse lately but there are so many other factors which could be the cause,so I can not understand what the problem is. I have some cold and/or allergic reactions. I have some fungus problem. My exhaustion ad brain problems getting worse. I am more at home so I am exposed more to home pollutants. So,I am not sure if B12 injections had any positive or negative effect in this picture? I am trying to find out that. Thanks Nil Re: B12 Injections Help, please > Nil; Do you feel an adverse reaction or a benefit from your injections? > Adrienne > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 8, 2004 Report Share Posted January 8, 2004 Nil, treat the b12 as a suspect food: Stay off it for awhile. See if anything gets better. Take another shot. See how you react to the shot. This is not guaranteed to work, but you might learn something. So sorry you are feeling worse. Adrienne Re: B12 Injections Help, please > Nil; Do you feel an adverse reaction or a benefit from your injections? > Adrienne > This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. ------------------------------------------------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 8, 2004 Report Share Posted January 8, 2004 I would stop the B12 for a short time and see if you get better or worse. I have been getting worse too for several months. I remember a few people saying they are worse in winter. I don't know if it is mold, lack of sun, or just random. Cindi ----- Original Message ----- From: Nil I seem to be getting worse lately but there are so many other factors which could be the cause,so I can not understand what the problem is. I have some cold and/or allergic reactions. I have some fungus problem. My exhaustion ad brain problems getting worse. Quote Link to comment Share on other sites More sharing options...
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