a doctor is paying attention

[Guest guest]

Hi all,

A young doctor we know at Yale found the following interesting enough to

forward it to us. He wrote with his forward: " Enterovirus causes a variety

of illnesses, including diarrhea, polio, and according to a virology

textbook I have, 'postviral fatigue syndrome.' "

I find it encouraging that a doctor in an unrelated field is paying

attention, consulting his virology textbook.

Sue B.

Upstate New York

=================================

From the AARP Bulletin, March 2004:

NEW CLUES TO CHRONIC FATIGUE

Researchers in France have found a probable cause for two painful

conditions that have long puzzled medical science.

They discovered traces of a virus in skeletal muscles of people with

chronic fatigue syndrome and fibromyalgia--but none in healthy volunteers.

The virus, known as entero-virus, also turned up in people with

inflammatory muscle diseases, says Fatima douche-Aourik of the medical

school at the University Hospital Center in Saint-Etienne.

The researchers believe a persistent infection caused by the virus may

explain these conditions, according to their report in vol. 71, Issue 4 of

the Journal of Medical Virology.

[Guest guest]

At 07:16 -0500 3/16/04, Ron wrote about a

doctor is paying attention:

|>From the AARP Bulletin, March 2004:

|

|NEW CLUES TO CHRONIC FATIGUE

|

| Researchers in France have found a probable cause for two painful

|conditions that have long puzzled medical science.

You can download the complete report in .pdf format from

http://www.cfids-cab.org/cfs-inform/Virus/douche-aourik.etal03.pdf

Makes an interesting read.

--

Tink

France

[Guest guest]

I've reviewed this work, but I think the interpretation of it might

need modification.

First, Enterovirus may be partially involved with the pathogenesis

of CFS/FMS, but in this study not all CFS/FMS patients have

enterovirus in the muscle.

IMO, it's likely that the immune dysfunction in CFS/FMS likely

allows opportunistic pathogens to invade & reside, such as

mycoplasma, enterovirus, staph...etc. If this happens, then they can

contribute to disease.

So IMO, enteroviruses are generally not primary pathogens, rather an

opportunistic one found in immuno-compromized individuals.

However, once a enterovirus is established in an immuno-compromised

individual, viruses can trigger a TLR response as does LPS & BLPs of

bacteria and in this way can contribute to pathogenicity.

> Hi all,

>

> A young doctor we know at Yale found the following interesting

enough to

> forward it to us. He wrote with his forward: " Enterovirus causes

a variety

> of illnesses, including diarrhea, polio, and according to a

virology

> textbook I have, 'postviral fatigue syndrome.' "

>

> I find it encouraging that a doctor in an unrelated field is paying

> attention, consulting his virology textbook.

>

> Sue B.

> Upstate New York

> =================================

>

> From the AARP Bulletin, March 2004:

>

> NEW CLUES TO CHRONIC FATIGUE

>

> Researchers in France have found a probable cause for two

painful

> conditions that have long puzzled medical science.

>

> They discovered traces of a virus in skeletal muscles of

people with

> chronic fatigue syndrome and fibromyalgia--but none in healthy

volunteers.

>

> The virus, known as entero-virus, also turned up in people

with

> inflammatory muscle diseases, says Fatima douche-Aourik of the

medical

> school at the University Hospital Center in Saint-Etienne.

>

> The researchers believe a persistent infection caused by the

virus may

> explain these conditions, according to their report in vol. 71,

Issue 4 of

> the Journal of Medical Virology.